Food biomacromolecules.,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 11, 2024
Abstract
In
the
recent
years,
various
strains
of
gut
microbiota
have
been
discovered
to
possess
significant
therapeutic
potential,
they
are
defined
as
next‐generation
probiotics
(NGPs).
Akkermansia
,
Faecalibacterium
Bacteriodes
Eubacterium,
and
Bifidobacteria
among
typical
NGP
which
exhibit
several
interesting
bioactivities
live
biotherapeutics.
However,
some
extremely
sensitive
oxygen,
such
prausnitzii
.
This
hinders
their
cultivation
large‐scale
production.
Therefore,
it
is
essential
develop
a
strategy
protect
them
during
production,
storage,
colonic
administration.
review,
highlights
key
developed
in
alongside
encapsulation
strategies
used
them.
The
primary
criterion
for
selecting
encapsulating
techniques
feasibility
be
performed
under
strictly
anaerobic
conditions.
Various
processes
selected
according
physical
forms
products,
including
liquid,
gel,
solid
forms,
well
final
shaping
product.
critical
factors
materials
include
biocompatibility,
safety,
effective
oxygen
barrier
properties,
an
optimal
release
profile
gastrointestinal
tract.
review
discusses
protection
aimed
at
improving
survival
thereby
effectiveness
NGPs.
MicrobiologyOpen,
Journal Year:
2024,
Volume and Issue:
13(2)
Published: March 31, 2024
Abstract
Microbial
products
are
essential
for
developing
various
therapeutic
agents,
including
antibiotics,
anticancer
drugs,
vaccines,
and
enzymes.
Genetic
engineering
techniques,
functional
genomics,
synthetic
biology
unlock
previously
uncharacterized
natural
products.
This
review
highlights
major
advances
in
microbial
biotechnology,
focusing
on
gene‐based
technologies
medical
applications.
Open Life Sciences,
Journal Year:
2024,
Volume and Issue:
19(1)
Published: Jan. 1, 2024
Abstract
Inflammatory
bowel
disease
(IBD)
refers
to
chronic
inflammatory
disorders
of
the
gut.
Ulcerative
colitis
(UC)
and
Crohn’s
(CD)
are
two
subtypes
IBD.
Evidence
suggests
that
intestinal
microbiota
plays
a
role
in
pathogenesis
IBD,
so
probiotics
have
garnered
lot
interest
as
potential
treatment
or
prevention
for
However,
clinical
evidence
efficacy
is
still
debatable.
We
performed
literature
review.
An
advanced
search
considered
studies
on
probiotic
IBD
from
inception
2023
PubMed,
Embase,
Cochrane
Library,
Web
Science.
In
UC
with
probiotics,
only
Escherichia
coli
Nissle
1917
maintenance
remission,
Bifidobacterium
VSL#3
induction
remission
patients
mild
moderately
active
shown
strong
evidence.
Currently,
there
no
definitive
conclusions
regarding
effectiveness
CD.
The
mechanism
may
be
related
reducing
oxidative
stress,
repairing
barrier,
regulating
flora
balance,
modulating
immune
response.
Differences
benefits
between
CD
attributable
different
lesion
extent
immune-mediated
pathophysiology.
More
robust
randomized
trials
required
validate
safety
diverse
strains
Microorganisms,
Journal Year:
2024,
Volume and Issue:
12(2), P. 323 - 323
Published: Feb. 4, 2024
The
gut
microbiota
has
been
implicated
in
the
context
of
sexual
maturation
during
puberty,
with
discernible
differences
its
composition
before
and
after
this
critical
developmental
stage.
Notably,
there
a
global
rise
prevalence
precocious
puberty
recent
years,
particularly
among
girls,
where
approximately
90%
central
cases
lack
clearly
identifiable
cause.
While
link
between
observed,
precise
causality
underlying
mechanisms
remain
elusive.
This
narrative
review
aims
to
systematically
elucidate
potential
that
underlie
intricate
relationship
puberty.
Potential
avenues
exploration
include
investigating
impact
on
endocrine
function,
regulation
hormones,
such
as
gonadotropin-releasing
hormone
(GnRH),
luteinizing
(LH),
follicle-stimulating
(FSH).
Additionally,
will
delve
into
interplay
microbiome,
metabolism,
obesity,
considering
known
association
obesity
also
explore
how
microbiome's
involvement
nutrient
metabolism
could
Finally,
attention
is
given
microbiota's
ability
produce
neurotransmitters
neuroactive
compounds,
potentially
influencing
nervous
system
components
involved
regulating
By
exploring
these
mechanisms,
seeks
identify
unexplored
targets
emerging
directions
understanding
role
microbiome
relation
ultimate
goal
provide
valuable
insights
for
development
non-invasive
diagnostic
methods
innovative
therapeutic
strategies
future,
specific
probiotic
therapy.
Comprehensive Reviews in Food Science and Food Safety,
Journal Year:
2024,
Volume and Issue:
23(3)
Published: April 10, 2024
Abstract
Adequate
intake
of
live
probiotics
is
beneficial
to
human
health
and
wellbeing
because
they
can
help
treat
or
prevent
a
variety
conditions.
However,
the
viability
reduced
by
harsh
environments
experience
during
passage
through
gastrointestinal
tract
(GIT).
Consequently,
oral
delivery
viable
significant
challenge.
Probiotic
encapsulation
provides
potential
solution
this
problem.
production
methods
used
create
conventional
technologies
often
damage
probiotics.
Moreover,
systems
produced
do
not
have
required
physicochemical
attributes
robustness
for
food
applications.
Single‐cell
based
on
forming
protective
coating
around
single
probiotic
cell.
These
coatings
may
be
biofilms
biopolymer
layers
designed
protect
from
environment,
enhance
their
colonization,
introduce
additional
functions.
This
article
reviews
factors
affecting
probiotics,
analyses
shortcomings
existing
technologies,
highlights
advantages
single‐cell
encapsulation.
It
also
various
approaches
available
including
implementation
characteristics
produce.
In
addition,
mechanisms
which
improve
bioavailability
benefits
are
described.
benefits,
limitations,
safety
issues
technology
applications
in
beverages
analyzed.
Finally,
future
directions
challenges
widespread
adoption
highlighted.
Foods,
Journal Year:
2024,
Volume and Issue:
13(5), P. 721 - 721
Published: Feb. 27, 2024
The
daylily
(Hemerocallis
citrina
Baroni)
flower
is
a
traditional
raw
food
material
that
rich
in
variety
of
nutrients.
In
particular,
the
content
polysaccharides
abundant
and
has
been
widely
used
as
functional
component
food,
cosmetics,
medicine,
other
industries.
However,
studies
on
structure-effective
relationship
are
still
lacking.
view
this,
were
isolated
purified,
their
physical
chemical
properties,
structure,
antioxidant
activity,
adhesion-promoting
effect
probiotics
evaluated.
results
showed
novel
water-soluble
polysaccharide
(DPW)
with
an
average
molecular
weight
(Mw)
2.224
kDa
could
be
successfully
using
column
chromatography.
Monosaccharide
composition
analysis
DPW
only
comprised
glucose
fructose,
molar
ratio
0.242:0.758.
Through
methylation
nuclear
magnetic
resonance
(NMR)
analysis,
it
was
inferred
belonged
to
fructans
group
structure
α-D-Glcp-1→2-β-D-Fruf-1→(2-β-D-Fruf-1)n→.
Antioxidant
strong
2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-Oxide
(PTIO-scavenging
activity
IC50
1.54
mg/mL.
1.25
5
mg/mL
significantly
increase
adhesion
rate
Lactobacillus
acidophilu,
casei,
Bifidobacterium
adolescentis,
plantarum
Caco-2
cells.
Considering
above
results,
present
study
provides
theoretical
basis
practical
support
for
development
application
active
ingredient.
