High-performance and multifunctional organic field-effect transistors

Chinese Chemical Letters, Journal Year: 2022, Volume and Issue: 34(9), P. 108094 - 108094

Published: Dec. 27, 2022

Language: Английский

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Suprasomes Based on Host–Guest Molecular Recognition: An Excellent Alternative to Liposomes in Cancer Theranostics

Angewandte Chemie International Edition, Journal Year: 2022, Volume and Issue: 61(52)

Published: Oct. 20, 2022

Abstract Liposomes and polymersomes, typical vesicular drug delivery systems (DDSs), have faced some limitations in cancer theranostics. Suprasomes, supramolecular vesicles assembled from amphiphiles linked by noncovalent interactions, show potential as new generation of DDSs. We construct suprasomes based on host–guest recognition, which the desired functions can be integrated into carriers without tedious synthesis. Photothermally active complex is formed between a functional guest pillar[5]arene, further self‐assembles hollow suprasomes. A nanomedicine developed encapsulating cisplatin The obtained cisplatin@Suprasomes achieve excellent anticancer efficacy anti‐metastasis combining chemotherapy photothermal therapy, ablate tumors relapse metastasis. This work demonstrates facile functionalization suprasomes, holding promise alternatives to liposomes polymersomes.

Language: Английский

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Multifunctional nanoparticles precisely reprogram the tumor microenvironment and potentiate antitumor immunotherapy after near-infrared-II light-mediated photothermal therapy

Acta Biomaterialia, Journal Year: 2023, Volume and Issue: 167, P. 551 - 563

Published: June 10, 2023

Language: Английский

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Key progresses of MOE key laboratory of macromolecular synthesis and functionalization in 2023

Chinese Chemical Letters, Journal Year: 2024, Volume and Issue: 35(11), P. 109893 - 109893

Published: April 17, 2024

Language: Английский

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Photo-steered rapid and multimodal locomotion of 3D-printed tough hydrogel robots

Materials Horizons, Journal Year: 2024, Volume and Issue: 11(9), P. 2143 - 2152

Published: Jan. 1, 2024

Hydrogels are an ideal material to develop soft robots. However, it remains a grand challenge miniaturized hydrogel robots with mechanical robustness, rapid actuation, and multi-gait motions. Reported here is facile strategy fabricate hydrogel-based by three-dimensional (3D) printing of responsive nonresponsive tough gels for programmed morphing locomotion upon stimulations. Highly viscoelastic poly(acrylic acid-co-acrylamide) acid-co-N-isopropyl acrylamide) aqueous solutions, as well their mixtures, printed multiple nozzles into 3D constructs followed incubation in solution zirconium ions form robust carboxyl-Zr4+ coordination complexes, produce metallo-supramolecular fibers. Gold nanorods incorporated ink afford response light. Owing the excellence small diameter gel fibers, exhibit high fast response, agile motions when remotely steered dynamic The design steering spatiotemporal light allow multimodal programmable trajectories can walk, turn, flip, transport cargos Such hydrogels good performances, may open opportunities biomedical engineering fields.

Language: Английский

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Recent Progress in 3D Printing of Polymer Materials as Soft Actuators and Robots

Chem & Bio Engineering, Journal Year: 2024, Volume and Issue: 1(4), P. 312 - 329

Published: April 18, 2024

With inspiration from natural systems, various soft actuators and robots have been explored in recent years with versatile applications biomedical engineering fields. Soft active materials rich stimulus-responsive characteristics an ideal candidate to devise these machines by using different manufacturing technologies. Among technologies, three-dimensional (3D) printing shows advantages fabricating constructs multiple sophisticated architectures. In this Review, we aim provide overview of progress on 3D materials, robotics performances, representative applications. Typical techniques are briefly introduced, followed state-of-the-art advances hydrogels, shape memory polymers, liquid crystalline elastomers, their hybrids as robots. From the perspective material properties, commonly used action-generation principles for typical printed discussed. Actuation locomotive behaviors, summarized. The relationship between structures action performances is also Finally, limitations each compared, remaining challenges future directions field prospected.

Language: Английский

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Multi-level encryption of information in morphing hydrogels with patterned fluorescence

Soft Matter, Journal Year: 2022, Volume and Issue: 18(11), P. 2149 - 2156

Published: Jan. 1, 2022

Fluorescent hydrogels have attracted tremendous attention recently in the field of information security due to booming development technology. Along this line, it is highly desired improve level concealed by advancements materials and encryption technologies. Here we report multi-level a bilayer hydrogel with shape-morphing ability patterned fluorescence. This composed fluorescence layer containing chromophore units poly(acrylic acid) network an active UV-absorption agents poly(N-isopropylacrylamide-co-acrylic network. The former exhibits tunable tailored UV light irradiation induce unimer-to-dimer transformation chromophores, facilitating write-in through photolithography. latter responsive temperature, enabling morphing hydrogel. Therefore, encoded fluorescent patterns can deform into three-dimensional configurations at room temperature conceal information, which readable only after successive procedures shape recovery appropriate under from right direction. combination as new avenue should merit design other smart integrated functions for specific applications.

Language: Английский

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Exploring Possible Ways to Enhance the Potential and Use of Natural Products through Nanotechnology in the Battle against Biofilms of Foodborne Bacterial Pathogens

Pathogens, Journal Year: 2023, Volume and Issue: 12(2), P. 270 - 270

Published: Feb. 7, 2023

Biofilms enable pathogenic bacteria to survive in unfavorable environments. As biofilm-forming pathogens can cause rapid food spoilage and recurrent infections humans, especially their presence the industry is problematic. Using chemical disinfectants prevent biofilm formation raises serious health concerns. Further, ability of bacterial tolerate disinfection procedures questions traditional treatment methods. Thus, there a dire need for alternative options targeting pathogens, biofilms. clean-label products without carcinogenic hazardous potential, natural compounds with growth biofilm-inhibiting biofilm-eradicating potentials have gained popularity as preservatives industry. However, use these restricted by poor availability, stability during processing storage. Also lack standardization, unattractive organoleptic qualities. Nanotechnology one way get around limitations well underutilized bioactives. The nanotechnology has several advantages including traversing matrix, targeted drug delivery, controlled release, enhanced bioavailability, bioactivity, stability. nanoparticles used fabricating or encapsulating are considered an appealing antibiofilm strategy since enhance activity against biofilms foodborne pathogens. Hence, this literature review intended provide comprehensive analysis current methods delivery (biofabrication, encapsulation, nanoemulsion) also discuss different promising strategies employed recent past inhibition eradication

Language: Английский

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Chemical and Enzyme‐Mediated Chemical Reactions for Studying Nucleic Acids and Their Modifications

ChemBioChem, Journal Year: 2024, Volume and Issue: 25(15)

Published: May 14, 2024

Nucleic acids are genetic information-carrying molecules inside cells. Apart from basic nucleotide building blocks, there exist various naturally occurring chemical modifications on nucleobase and ribose moieties, which greatly increase the encoding complexity of nuclei acids, contribute to alteration nucleic acid structures, play versatile regulation roles in gene expression. To study functions certain biological contexts, robust tools specifically label identify these macromolecules their modifications, illuminate structures highly necessary. In this review, we summarize recent technique advances using enzyme-mediated reactions structures. By highlighting principles techniques, aim present a perspective advancement field as well offer insights into developing specific precise enzyme catalysis utilized for modifications.

Language: Английский

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Crystallization from a Droplet: Single-Crystalline Arrays and Heterojunctions for Organic Electronics

Accounts of Chemical Research, Journal Year: 2021, Volume and Issue: 54(24), P. 4498 - 4507

Published: Dec. 6, 2021

ConspectusSingle crystals of organic semiconductors (OSCs) are believed to have both high mobility and intrinsic flexibility, making them promising candidates for flexible electronic/optoelectronic applications being consistently pursued by researchers. The van der Waals force in OSC enables low-temperature solution processing single crystals, but the relatively weak binding energy brings challenges forming large, uniform, defect-free crystals. To promote study on a generalized method that grows high-quality an easy-to-handle, time/resource-saving, repeatable manner is apparently necessary. In 2012, Li et al. developed droplet-pinned crystallization (DPC) uses rather simple strategy create steadily receding contact line growth Instead setting up expensive equipment, controlling strict deposition parameters, or waiting days weeks countable crystal seeds, DPC offers time- cost-effective way obtain further tendency crystallization, single-crystal mobility, molecular packing information. primarily powerful tool studying charge-transport mechanisms pioneering work, high-mobility p-type 6,13-bis(triisopropylsilylethynyl) pentacene (TIPS-PEN) n-type C60 materials were obtained. Driven demands from practical applications, we then focused general lagging electron materials. ambipolar property TIPS-PEN was studied, strong correlation between polar species (polar solvent residuals surface hydroxyl groups) observed. latter guided harvest series Undoubtfully, facile accelerated these studies providing time-efficient, reliable, testing platform. Additionally, flexibility solvents, where not only one-component also binary systems allowed, another critical integrity method. m-xylene/carbon tetrachloride proven be efficient growing ribbon-like than needle-like typical solvents. Afterward, variety (including p-type, n-type, ones) solvents aromatic, aliphatic, studied. found at either top liquid-air interface bottom solid-liquid interface. interactions molecules substrate surfaces deduced as qualitative determining factor. By utilizing two-step sequential single-crystalline heterojunctions enabled. Moreover, selecting appropriate pairs crystallize separate interfaces, one-step formation achieved. horizontal, vertical, bulk heterojunctions) thereof exhibit potentials circuits, photovoltaics, photodiodes would probably provide new insights future development electronics.

Language: Английский

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