Self-perception of cognitive sequels in post-COVID-19 individuals DOI Creative Commons
Emily Viega Alves, Bárbara Costa Beber

Dementia & Neuropsychologia, Journal Year: 2023, Volume and Issue: 17

Published: Jan. 1, 2023

COVID-19 is an infection, primarily respiratory, caused by the SARS-CoV-2, which can also affect central nervous system, causing neuropsychological damage. There are studies describing post-COVID-19 cognitive deficits, but it important to know this outcome in populations with different social, biological, and cultural characteristics.The aim of study was assess self-perception sequelae individuals identify whether there a possible relationship between participants' sociodemographic clinical data.This cross-sectional study, carried out through online questionnaire on Google Forms platform, data, general health manifestations COVID-19, domains memory, attention, language, executive functions were collected.The final sample consisted 137 participants, that memory attention highest impression worsening post-COVID-19, followed language. In addition, identified being female may be related worse all having depression or other psychiatric diseases obesity significantly at least half evaluated.This pointed participants.A é uma infecção, primariamente respiratória, causada pelo vírus mas que também pode atingir o sistema nervoso central, ocasionando danos neuropsicológicos. Há estudos descrevem os déficits cognitivos pós-COVID-19, importante conhecer esse desfecho em populações com diferentes características sociais, biológicas e culturais.Avaliar autopercepção de sequelas cognitivas indivíduos pós-COVID-19 identificar se há possível relação entre da dos participantes dados sociodemográficos clínicos.Trata-se um estudo transversal, realizado uso questionário na plataforma Forms, no qual foram identificados sociodemográficos, saúde geral, manifestações clínicas domínios memória, atenção, linguagem funções executivas pós-COVID-19.A amostra foi composta participantes, pôde-se observar memória atenção maior impressão piora seguidos por linguagem. Além disso, constatou-se ser do gênero feminino estar relacionado pior todas as ter depressão ou outras doenças psiquiátricas obesidade afetar significativamente menos metade avaliados.Este trabalho apontou para cognitiva participantes.

Global Prevalence of Post-Coronavirus Disease 2019 (COVID-19) Condition or Long COVID: A Meta-Analysis and Systematic Review DOI Open Access
Chen Chen, Spencer R. Haupert, Lauren Zimmermann

et al.

The Journal of Infectious Diseases, Journal Year: 2022, Volume and Issue: 226(9), P. 1593 - 1607

Published: April 14, 2022

Abstract Background This study aims to examine the worldwide prevalence of post-coronavirus disease 2019 (COVID-19) condition, through a systematic review and meta-analysis. Methods PubMed, Embase, iSearch were searched on July 5, 2021 with verification extending March 13, 2022. Using random-effects framework DerSimonian-Laird estimator, we meta-analyzed post-COVID-19 condition at 28+ days from infection. Results Fifty studies included, 41 meta-analyzed. Global estimated pooled was 0.43 (95% confidence interval [CI], .39–.46). Hospitalized nonhospitalized patients had estimates 0.54 CI, .44–.63) 0.34 .25–.46), respectively. Regional Asia (0.51; 95% .37–.65), Europe (0.44; .32–.56), United States America (0.31; .21–.43). for 30, 60, 90, 120 after infection be 0.37 .26–.49), 0.25 .15–.38), 0.32 .14–.57), 0.49 .40–.59), Fatigue most common symptom reported 0.23 .17–.30), followed by memory problems (0.14; .10–.19). Conclusions finds is substantial; health effects COVID-19 seem prolonged can exert stress healthcare system.

Language: Английский

Citations

1031
Neuropsychiatric aspects of long COVID: A comprehensive review DOI Creative Commons
Takafumi Kubota, Naoto Kuroda, Daichi Sone

et al.

Psychiatry and Clinical Neurosciences, Journal Year: 2022, Volume and Issue: 77(2), P. 84 - 93

Published: Nov. 17, 2022

Although some patients have persistent symptoms or develop new following coronavirus disease 2019 (COVID-19) infection, neuropsychiatric aspects of long COVID are not well known. This review summarizes and provides an update on the dimensions COVID. Its manifestations commonly include fatigue, cognitive impairment, sleep disorders, depression, anxiety, post-traumatic stress disorder. There no specific tests for COVID, but characteristic findings such as hypometabolism positron emission tomography been reported. The possible mechanisms inflammation, ischemic effects, direct viral invasion, social environmental changes. Some patient characteristics severity complications acute COVID-19 infection may be associated with increased risk symptoms. Long resolve spontaneously persist, depending type established treatments lacking, various psychological pharmacological attempted. Vaccination against plays a key role in prevention disease. With differences among SARS-CoV-2 variants, including omicron variant, likely to change future. Further studies clarifying effective warranted.

Language: Английский

Citations

85
Sequelae of COVID-19 among previously hospitalized patients up to 1 year after discharge: a systematic review and meta-analysis DOI Open Access
Tianqi Yang, Zhipeng Yan, Xingyi Li

et al.

Infection, Journal Year: 2022, Volume and Issue: 50(5), P. 1067 - 1109

Published: June 24, 2022

Language: Английский

Citations

69
The global prevalence of depression, anxiety, and sleep disorder among patients coping with Post COVID-19 syndrome (long COVID): a systematic review and meta-analysis DOI Creative Commons
Niloofar Seighali, Abolfazl Abdollahi, Arman Shafiee

et al.

BMC Psychiatry, Journal Year: 2024, Volume and Issue: 24(1)

Published: Feb. 6, 2024

Post COVID-19 syndrome, also known as "Long COVID," is a complex and multifaceted condition that affects individuals who have recovered from SARS-CoV-2 infection. This systematic review meta-analysis aim to comprehensively assess the global prevalence of depression, anxiety, sleep disorder in coping with syndrome.

Language: Английский

Citations

50
Post-viral fatigue in COVID-19: A review of symptom assessment methods, mental, cognitive, and physical impairment DOI
Maria Cristine Campos, Tatyana Nery,

Ana Carolina Starke

et al.

Neuroscience & Biobehavioral Reviews, Journal Year: 2022, Volume and Issue: 142, P. 104902 - 104902

Published: Oct. 3, 2022

Language: Английский

Citations

40
Post-acute sequelae of SARS-CoV-2 associates with physical inactivity in a cohort of COVID-19 survivors DOI Creative Commons
Saulo Gil, Bruno Gualano, Adriana Ladeira de Araújo

et al.

Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)

Published: Jan. 5, 2023

The aim of this study was to determine whether Post-acute Sequelae SARS-CoV-2 Infection (PASC) are associated with physical inactivity in COVID-19 survivors. This is a cohort survivors discharged from tertiary hospital Sao Paulo, Brazil. Patients admitted as inpatients due laboratory-confirmed between March and August 2020 were consecutively invited for follow-up in-person visit 6 11 months after hospitalization. Ten symptoms PASC assessed using standardized scales. Physical activity by questionnaire participants classified according WHO Guidelines. 614 patients analyzed (age: 56 ± 13 years; 53% male). Frequency exhibiting none, at least 1, 1-4, 5 or more 51%, 62%, 58%, 71%, respectively. Adjusted models showed that one persistent have greater odds being physically inactive than those without any (OR: 1.57 [95% CI 1.04-2.39], P = 0.032). Dyspnea 2.22 [1.50-3.33], < 0.001), fatigue 2.01 [1.40-2.90], insomnia 1.69 [1.16-2.49], 0.007), post-traumatic stress 1.53 [1.05-2.23], 0.028), severe muscle/joint pain 1.08-2.17], 0.011) inactive. suggests inactivity, which itself may be considered symptom among help the early identification who could benefit additional interventions tailored combat (even treatment PASC), potential beneficial impacts on overall morbidity/mortality health systems worldwide.

Language: Английский

Citations

30
Cognitive impairment in long-COVID and its association with persistent dysregulation in inflammatory markers DOI Creative Commons
Rodolfo Furlan Damiano, Cristiana Castanho de Almeida Rocca, Antônio de Pádua Serafim

et al.

Frontiers in Immunology, Journal Year: 2023, Volume and Issue: 14

Published: May 23, 2023

To analyze the potential impact of sociodemographic, clinical and biological factors on long-term cognitive outcome patients who survived moderate severe forms COVID-19.We assessed 710 adult participants (Mean age = 55 ± 14; 48.3% were female) 6 to 11 months after hospital discharge with a complete battery, as well psychiatric, laboratory evaluation. A large set inferential statistical methods was used predict variables associated any impairment, focus panel 28 cytokines other blood inflammatory disease severity markers.Concerning subjective assessment performance, 36.1% reported slightly poorer overall 14.6% being severely impacted, compared their pre-COVID-19 status. Multivariate analysis found sex, age, ethnicity, education, comorbidity, frailty physical activity general cognition. bivariate that G-CSF, IFN-alfa2, IL13, IL15, IL1.RA, EL1.alfa, IL45, IL5, IL6, IL7, TNF-Beta, VEGF, Follow-up C-Reactive Protein, D-Dimer significantly (p<.05) However, LASSO regression included all follow-up variables, markers did not support these findings.Though we identified several sociodemographic characteristics might protect against impairment following SARS-CoV-2 infection, our data do prominent role for status (both during acute long-stage COVID-19) or background (also explain deficits can follow COVID-19 infection.

Language: Английский

Citations

25
Cognitive domains affected post‐COVID‐19; a systematic review and meta‐analysis DOI Creative Commons
Jack B. Fanshawe, Brendan Sargent, James Badenoch

et al.

European Journal of Neurology, Journal Year: 2024, Volume and Issue: unknown

Published: Feb. 20, 2024

Abstract Background and purpose This review aims to characterize the pattern of post‐COVID‐19 cognitive impairment, allowing better prediction impact on daily function inform clinical management rehabilitation. Methods A systematic meta‐analysis neurocognitive sequelae following COVID‐19 was conducted, PRISMA‐S guidelines. Studies were included if they reported domain‐specific assessment in patients with at >4 weeks post‐infection. deemed high‐quality had >40 participants, utilized healthy controls, low attrition rates mitigated for confounders. Results Five seven primary Diagnostic Statistical Manual Mental Disorders (DSM‐5) domains assessed by enough studies facilitate meta‐analysis. Medium effect sizes indicating impairment versus controls seen across executive (standardised mean difference (SMD) −0.45), learning memory (SMD −0.55), complex attention −0.54) language −0.54), perceptual motor appearing be impacted a greater degree −0.70). narrative synthesis 56 low‐quality also suggested no obvious impairment. Conclusions found moderate impairments multiple cognition post‐COVID‐19, specific pattern. The literature significantly heterogeneous, wide variety tasks, small sample disparate initial disease severities limiting interpretability. finding consistent range tasks suggests broad, as opposed domain‐specific, brain dysfunction. Future should utilize harmonized test battery inter‐study comparisons, whilst accounting interactions between COVID‐19, neurological mental health, interplay which might explain

Language: Английский

Citations

8
A systematic analysis of the literature on the post-COVID-19 condition in Latin America focusing on epidemiology, clinical characteristics, and risk of bias DOI Creative Commons
Vivienne C. Bachelet, Belén Carroza, Bruno Morgado

et al.

Medwave, Journal Year: 2025, Volume and Issue: 25(01), P. e3014 - e3014

Published: Jan. 16, 2025

This analysis article aimed to identify and analyze all articles published on the post-COVID-19 condition in Latin America Caribbean, focusing epidemiology, clinical characteristics, risk of bias. We did a systematic survey literature with broad inclusion criteria. The only exclusion criteria were referring post-acute COVID-19 sequelae after an intensive care unit stay, which we distinguish from condition. searched MEDLINE/PubMed, LILACS, SciELO, Scopus, Web Science, Epistemonikos. included 55 records, 48 original (44 observational research, 29 had comparison group; four reviews). Various definitions for long COVID reported, or none, few used World Health Organization None studies reported prevalence rates region. extracted signs symptoms our Using Johanna Briggs Institute critical appraisal tools analytic found that most prone limitations biases. conclude more research should be done using rigorous study designs inform public health strategies.

Language: Английский

Citations

1
Neurocognitive Impairment in Long COVID: A Systematic Review DOI Creative Commons

Ευγενία Παναγέα,

Lambros Messinis,

Maria Christina Petri

et al.

Archives of Clinical Neuropsychology, Journal Year: 2024, Volume and Issue: unknown

Published: June 8, 2024

Abstract Objective Although Coronavirus disease 2019 (COVID-19) is primarily a respiratory infectious disease, it has also been associated with wide range of other clinical manifestations. It widely accepted in the scientific community that many patients after recovery continue to experience COVID-19-related symptoms, including cognitive impairment. The aim this systematic review was investigate profile long-COVID syndrome. Methods A search empirical studies conducted through PubMed/Medline and Scopus electronic databases. Cross-sectional longitudinal published between 2020 2023 were included. Results Of 516 assessed for eligibility, 36 met inclusion criteria. All included support presence persistent changes COVID-19 disease. Executive function, memory, attention, processing speed appear be domains are predominantly syndrome, whereas language an area not sufficiently investigated. Conclusions In review, high frequency impairment evident. If we consider functioning affects our ability live independently key determinant quality life, imperative precisely define those factors may induce survivors, ultimate goal early diagnosis and, consequently, development targeted rehabilitation interventions address them.

Language: Английский

Citations

6