Prevalence and risk factors for ototoxicity after cisplatin-based chemotherapy DOI
Victoria A. Sanchez, Paul C. Dinh,

Jennessa Rooker

et al.

Journal of Cancer Survivorship, Journal Year: 2023, Volume and Issue: 17(1), P. 27 - 39

Published: Jan. 13, 2023

Language: Английский

Estimating the global costs of hearing loss DOI Creative Commons
David McDaid, A‐La Park, Shelly Chadha

et al.

International Journal of Audiology, Journal Year: 2021, Volume and Issue: 60(3), P. 162 - 170

Published: Feb. 16, 2021

Objective To estimate the global costs of hearing loss in 2019.Design Prevalence-based costing model.Study sample Hearing data from 2019 Global Burden Disease study. Additional non-hearing related health care costs, educational support, exclusion labour force countries with full employment and societal posed by lost quality life were determined. All reported purchasing power parity (PPP) adjusted international dollars.Results Total economic exceeded $981 billion. 47% to losses, 32% due additional poor people loss. 57% outside high-income countries. 6.5% for children aged 0–14. In scenario analysis a 5% reduction prevalence would reduce $49 billion.Conclusion This highlights major consequences not taking action address worldwide. Small reductions and/or severity could avert substantial society. These cost estimates can also be used help modelling effectiveness interventions prevent/tackle strengthen case investment.

Language: Английский

Citations

129

The Quest for Ecological Validity in Hearing Science: What It Is, Why It Matters, and How to Advance It DOI Creative Commons

Gitte Keidser,

Graham Naylor, Douglas S. Brungart

et al.

Ear and Hearing, Journal Year: 2020, Volume and Issue: 41(Supplement 1), P. 5S - 19S

Published: Oct. 23, 2020

Ecological validity is a relatively new concept in hearing science. It has been cited as relevant with increasing frequency publications over the past 20 years, but without any formal conceptual basis or clear motive. The sixth Eriksholm Workshop was convened to develop deeper understanding of for purpose applying it research consistent and productive manner. Inspired by debate within field psychology, taking into account World Health Organization's International Classification Functioning, Disability, framework, attendees at workshop reached consensus on following definition: "In science, ecological refers degree which findings reflect real-life hearing-related function, activity, participation." Four broad purposes striving greater were determined: A (Understanding) better role everyday life; B (Development) supporting development improved procedures interventions; C (Assessment) facilitating methods assessing predicting ability accomplish real-world tasks; D (Integration Individualization) enabling more integrated individualized care. Discussions considered effects variables phenomena commonly present level outcomes, supported examples from few selected outcome domains different types studies. Illustrated examples, potential strategies offered promoting high study how evaluate study. Areas particular that could benefit advance science include: (1) processes communication listening situations, specifically factors make difficult situations; (2) developing test paradigms include than one person (e.g., encompass interactive nature communication) are integrative other interact function; (3) integrating emerging technologies virtual reality) established methods; (4) identifying key affecting verifiable ways increase derive set benchmarks strive for.

Language: Английский

Citations

126

Can Hearing Aids Delay Time to Diagnosis of Dementia, Depression, or Falls in Older Adults? DOI
Elham Mahmoudi,

Tanima Basu,

Kenneth M. Langa

et al.

Journal of the American Geriatrics Society, Journal Year: 2019, Volume and Issue: 67(11), P. 2362 - 2369

Published: Sept. 4, 2019

OBJECTIVE To examine the association between hearing aids (HAs) and time to diagnosis of Alzheimer disease (AD) or dementia, anxiety depression, injurious falls among adults, aged 66 years older, within 3 loss (HL) diagnosis. DESIGN Retrospective cohort study. SETTING We used 2008 2016 national longitudinal claims data (based on office visit, inpatient, outpatient healthcare encounters) from a large private payer. Kaplan‐Meier curves unadjusted disease‐free survival crude adjusted Cox regression models associations HAs three age‐related/HL‐associated conditions HL All were for age, sex, race/ethnicity, census divisions, prior cardiovascular conditions, hypertension, hypercholesterolemia, obesity, diabetes. PARTICIPANTS The participants included 114 862 diagnosed with HL. MEASUREMENT Diagnosis (1) AD dementia; (2) depression anxiety; (3) falls. INTERVENTION Use HAs. RESULTS Large sex racial/ethnic differences exist in HA use. Approximately 11.3% women vs 13.3% men (95% confidence interval [CI] difference = −0.024 −0.016). 13.6% whites CI 0.13‐0.14) 9.8% blacks 0.09‐0.11) 6.5% Hispanics 0.06‐0.07) risk‐adjusted hazard ratios being AD/dementia, anxiety/depression, after diagnosis, those who did not, 0.82 0.76‐0.89), 0.89 0.86‐0.93), 0.87 0.80‐0.95), respectively. CONCLUSIONS is associated delayed AD, anxiety, older adults Although we have shown an use reduced risk physical mental decline, randomized trials are needed determine whether, what extent, relationship causal. J Am Geriatr Soc 67:2362–2369, 2019

Language: Английский

Citations

102

Age-Related Hearing Loss: The Link between Inflammaging, Immunosenescence, and Gut Dysbiosis DOI Open Access
Dagmara Kociszewska, Srdjan M. Vlajkovic

International Journal of Molecular Sciences, Journal Year: 2022, Volume and Issue: 23(13), P. 7348 - 7348

Published: July 1, 2022

This article provides a theoretical overview of the association between age-related hearing loss (ARHL), immune system ageing (immunosenescence), and chronic inflammation. ARHL, or presbyacusis, is most common sensory disability that significantly reduces quality life has high economic impact. disorder linked to genetic risk factors but also influenced by lifelong cumulative effect environmental stressors, such as noise, otological diseases, ototoxic drugs. Age-related other disorders share mechanisms which often converge on low-grade inflammation known "inflammaging". Various stimuli can sustain inflammaging, including pathogens, cell debris, nutrients, gut microbiota. As result ageing, become defective, leading accumulation unresolved inflammatory processes in body. Gut microbiota plays central role inflammaging because it release mediators crosstalk with organ systems. A proinflammatory environment associated could leaky translocation bacterial metabolites distant organs via systemic circulation. Here, we postulate immunosenescence dysbiosis, accelerates cochlear degeneration, contributing development ARHL. Age-dependent dysbiosis was included hypothetical link should receive more attention future studies.

Language: Английский

Citations

41

Hearing loss and quality of life DOI
Jerry L. Punch,

Rose Hitt,

Sandi W. Smith

et al.

Journal of Communication Disorders, Journal Year: 2019, Volume and Issue: 78, P. 33 - 45

Published: Jan. 6, 2019

Language: Английский

Citations

67

Prevalence and impact of combined vision and hearing (dual sensory) impairment: A scoping review DOI Creative Commons
Tess Bright, Jacqueline Ramke, Justine Zhang

et al.

PLOS Global Public Health, Journal Year: 2023, Volume and Issue: 3(5), P. e0001905 - e0001905

Published: May 16, 2023

Hearing and vision impairments are common globally. They often considered separately in research, planning delivering services. However, they can occur concurrently, termed dual sensory impairment (DSI). The prevalence impact of hearing have been well-examined, but there has much less consideration DSI. aim this scoping review was to determine the nature extent evidence on Three databases were searched: MEDLINE, Embase Global Health (April 2022). We included primary studies systematic reviews reporting or No limits placed age, publication dates, country. Only where full text available English included. Two reviewers independently screened titles, abstract, texts. Data charted by two using a pre-piloted form. identified 183 reports 153 unique 14 articles. Most came from high-income countries (86% reports). Prevalence varied across reports, as did age groups participants definitions used. DSI increased with age. Impact examined three broad outcomes-psychosocial, participation, physical health. There strong trend towards poorer outcomes for people all categories compared one neither impairment, including activities daily living (worse 78% reports) depression (68%). This highlights that is relatively condition substantial impact, particularly among older adults. gap low middle-income countries. pressing need consensus position definition(s) standardisation enable reliable estimates be ascertained responsive services developed.

Language: Английский

Citations

22

Comprehensive Audiologic Analyses After Cisplatin-Based Chemotherapy DOI
Victoria A. Sanchez, Paul C. Dinh, Patrick O. Monahan

et al.

JAMA Oncology, Journal Year: 2024, Volume and Issue: 10(7), P. 912 - 912

Published: June 6, 2024

Cisplatin is highly ototoxic but widely used. Evidence lacking regarding cisplatin-related hearing loss (CRHL) in adult-onset cancer survivors with comprehensive audiologic assessments (eg, Words-in-Noise [WIN] tests, full-spectrum audiometry, and additional otologic measures), as well the progression of CRHL considering comorbidities, modifiable factors associated risk, cumulative cisplatin dose.

Language: Английский

Citations

6

Hearing Impairment Increases Economic Inequality DOI Creative Commons
So Young Kim, Chanyang Min, Dae Myoung Yoo

et al.

Clinical and Experimental Otorhinolaryngology, Journal Year: 2021, Volume and Issue: 14(3), P. 278 - 286

Published: March 30, 2021

Objectives. We evaluated changes in income levels a hearing-impaired population.Methods. The study subjects were selected from the Korean National Health Insurance Service-Health Screening Cohort data 2002 to 2015 of Koreans ≥40 years old. In total, 5,857 matched with 23,428 comparison participants. Differences between initial level and at 1, 2, 3, 4, 5 post-enrollment compared groups. interaction time hearing impairment/comparison was estimated.Results. Both group showed increased over time. group, 4 higher than (each P<0.001). all participants after 1–5 impairment statistically significant (P=0.021).Conclusion. increase relatively lower adult population; therefore, gap widened this population normal-hearing population.

Language: Английский

Citations

38

Hearing as an Independent Predictor of Postural Balance in 1075 Patients Evaluated for Dizziness DOI
Jan Erik Berge, Stein Helge Glad Nordahl, Hans Jørgen Aarstad

et al.

Otolaryngology, Journal Year: 2019, Volume and Issue: 161(3), P. 478 - 484

Published: April 23, 2019

To evaluate the association between hearing and postural balance.Retrospective cross-sectional study.Tertiary care otolaryngology clinic.Patients examined for suspected vestibular disorder were included in this study. The outcome variable was sway measured by static posturography during quiet standing with eyes closed. predictor pure-tone average threshold on best ear at 0.5, 1, 2, 3 kHz. Covariates age, sex, disease or asymmetry assessed bithermal caloric irrigation.In total, 1075 patients included. Increased a strong of increased (path length) after correcting age sex. A 10-dB increase loss predicted mean 6.0% path length (confidence interval, 2.9%-9.3%, P < .001). Of covariates, increasing (P .001) male sex = .009) significant predictors sway. effect also adjusting disease.Increased an independent instability, strongest ear. Unilateral did not seem to explain balance. Reduced is associated impaired balance, interventions prevent falls should be considered risk.

Language: Английский

Citations

36

The global hearing therapeutic pipeline: 2021 DOI
Beverley Isherwood, Ana Cláudia Gonçalves,

Rick Cousins

et al.

Drug Discovery Today, Journal Year: 2021, Volume and Issue: 27(3), P. 912 - 922

Published: Nov. 11, 2021

Language: Английский

Citations

32