Exploring the Relationship between Acute Coronary Syndrome, Lower Respiratory Tract Infections, and Atmospheric Pollution DOI Open Access
Paweł Muszyński, Elżbieta Pawluczuk,

T Januszko

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(17), P. 5037 - 5037

Published: Aug. 25, 2024

: Respiratory infections were found to be connected with the incidence of acute coronary syndrome (ACS). The proposed pathway this connection includes inflammation, oxidative stress, pro-coagulation, and atherosclerotic plaque destabilization. This can cause rapture thrombus formation, leading ACS. Our study aimed assess risk factors for artery thrombosis as a manifestation ACS lower respiratory tract (LRTIs) in patients

Language: Английский

Air quality and the risk of acute atrial fibrillation (EP-PARTICLES study): A nationwide study in Poland DOI Creative Commons
Anna Kurasz,

Gregory Lip,

Michał Święczkowski

et al.

European Journal of Preventive Cardiology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 15, 2025

Abstract Aim Air pollution remains the single largest environmental health risk factor, while atrial fibrillation (AF) is most prevalent arrhythmia globally. The study aimed to investigate relationship between short-term exposure air and acute AF admissions. Methods Individual data on hospitalization in years 2011-2020 were collected from National Health Fund Poland (ICD-10: I48.XX). To obtain high-resolution we applied a modelling method using GEM-AQ model. Associations admissions estimated generalized additive models with Poisson regression. Results Over analysed period, recorded 252,566 due AF. Each 10 µg/m3 increment of PM2.5 NO2 concentration, 1 SO2 ng/m3 benzo(a)pyrene (BaP) concentration day resulted 1.13% (0.70%−1.55%), 1.65% (1.05%−2.26%), 0.11% (0.01%−0.21%), 0.3% (0.04%−0.55%) increases admissions, respectively. estimates are larger for women older people. Stronger associations BaP concentrations poorly urbanized areas noted. Areas high gross domestic product levels more affected by increase concentrations, resulting 0.2% (1.001-1.003) Exposure-response functions show steeper slopes pollutant-outcome lower ranges exposures, far below World Organization (WHO) quality guideline norms. For zero-emission scenario, estimate avoidable - 5,873 (95% CI 3,679 8,047) 3,295 (2,108-4,477). Conclusions acts as triggering factor can be associated hospitalisations. have an impact even at WHO

Language: Английский

Citations

1
Environmental Exposome and Atrial Fibrillation: Emerging Evidence and Future Directions DOI Creative Commons
Sojin Y. Wass, Omar Hahad, Zain Ul Abideen Asad

et al.

Circulation Research, Journal Year: 2024, Volume and Issue: 134(8), P. 1029 - 1045

Published: April 11, 2024

There has been increased awareness of the linkage between environmental exposures and cardiovascular health disease. Atrial fibrillation is most common sustained cardiac arrhythmia, affecting millions people worldwide contributing to substantial morbidity mortality. Although numerous studies have explored role genetic lifestyle factors in development progression atrial fibrillation, potential impact determinants on this prevalent condition received comparatively less attention. This review aims provide a comprehensive overview current evidence encompassing such as air pollution, temperature, humidity, other meteorologic conditions, noise greenspace, social environment. We discuss existing from epidemiological mechanistic studies, critically evaluating strengths limitations these investigations underlying biological mechanisms through which may affect risk. Furthermore, we address implications findings for public clinical practice identify knowledge gaps future research directions emerging field.

Language: Английский

Citations

6
Impact of air pollution on cardiovascular aging DOI Creative Commons
Marin Kuntić, Ivana Kuntić, Omar Hahad

et al.

Mechanisms of Ageing and Development, Journal Year: 2023, Volume and Issue: 214, P. 111857 - 111857

Published: Aug. 21, 2023

The world population is aging rapidly, and by some estimates, the number of people older than 60 will double in next 30 years. With increase life expectancy, adverse effects environmental exposures start playing a more prominent role human health. Air pollution now widely considered most detrimental all risk factors, with studies estimating that almost 20% deaths globally could be attributed to poor air quality. Cardiovascular diseases are leading cause death worldwide continue account for significant percentage non-communicable disease burden. defined pathomechanisms major trigger cardiovascular old age. Effects factors on should health span reduce burden populations. In this review, we explore aging, from molecular mechanisms manifestations and, finally, age-related outcomes. We also distinction between healthy progression. Future efforts focus extending rather lifespan.

Language: Английский

Citations

15
Lower risk of atrial fibrillation associated with visible greenness within community life circle: Findings from a population-based study DOI Creative Commons

Yunchong Yao,

Tingting Dai, Xu Wang

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2025, Volume and Issue: 294, P. 118106 - 118106

Published: March 30, 2025

Language: Английский

Citations

0
The mediation effect of lipids, blood pressure and BMI between air pollutant mixture and atherosclerotic cardiovascular disease: The CHCN-BTH cohort study DOI Creative Commons
Bingxiao Li, Fuyuan Wen, Kuo Liu

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2023, Volume and Issue: 264, P. 115491 - 115491

Published: Sept. 18, 2023

The combine effect of air pollutant mixture on atherosclerotic cardiovascular disease (ASCVD) remain undefined. This study aims to explore the association between long-term exposure pollutants and ASCVD, focusing mediating role lipids, blood pressure BMI.This was based CHCN-BTH cohort study. annual concentrations PM2.5 constituents were sourced from in Tracking Air Pollution China (TAP) ChinaHighAirPollutants (CHAP) datasets 2014 2019. A Cox mixed-effects model used investigate associations ASCVD. combined impact assessed using Quantile g-Computation. Stratified, sensitivity, mediation analyses conducted.A total 27,134 participants aged 18-80 recruited present We found that each IQR increase PM2.5, PM1, NO2, O3, BC, SO42-, OM significantly associated with incidence hazard ratios (HRs) 95 % confidence interval (CI) 1.55 (1.35, 1.78), 1.46 (1.27, 1.67), 1.30 (1.21, 1.39), 1.66 (1.41,1.95), 2.14 (1.63, 2.83), 1.65 (1.25, 2.17) 1.92(1.52, 2.45), respectively. ASCVD 1.79 (1.46, 2.20), contributed 83.3 this effect. Mediation models suggested might be mediated through SBP, DBP, HDL-C, LDL-C, hsCRP BMI (mediation proportion range 1.3 26.1 %), Notably, HDL-C played roles 11.3 (7.0 %, 18.4), (17.7 38.1 %) 25.4 (15.4, 47.7 effects PM1 respectively.Long-term, high-level significantly an elevated risk particularly for PM2.5. Blood pressure, lipids BMI, especially may mediate

Language: Английский

Citations

9
Effect modification of dietary diversity on the association of air pollution with incidence, complications, and mortality of type 2 diabetes: Results from a large prospective cohort study DOI

Guzhengyue Zheng,

Hui Xia, Hui Shi

et al.

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 908, P. 168314 - 168314

Published: Nov. 4, 2023

Language: Английский

Citations

8
Impact of particulate matter on the incidence of atrial fibrillation and the risk of adverse clinical outcomes: A review DOI Creative Commons
Darío Mandaglio‐Collados, Raquel López‐Gálvez, Antonio J. Ruiz‐Alcaraz

et al.

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 880, P. 163352 - 163352

Published: April 4, 2023

Atrial fibrillation (AF) is common and increases the risk of stroke mortality. Previous studies have suggested that air pollution an important factor for new-onset AF. Herein, we review evidence regarding: 1) association between exposure to particulate matter (PM) AF, 2) worse clinical outcomes in patients with pre-existent AF their relation PM exposure. A selection 2000 2023 linking was performed through searches PubMed, Scopus, Web Science, Google Scholar. 17 from different geographical areas demonstrated associated increased although results were heterogeneous regarding temporal pattern (short- or long-term) ultimately related Most concluded 2 %–18 % per 10 μg/m3 increment PM2.5 PM10 concentrations, whereas incidence (percentage change incidence) 0.29 %–2.95 PM10. Evidence about adverse events scarce but 4 showed a higher mortality (between 8 %–64 terms hazard ratio) when higher. Exposure (both PM10) who already suffer Since relationship independent region world, should be considered as global both patients. Specific measures prevent need adopted.

Language: Английский

Citations

7
Associations of ambient air pollution with incidence and dynamic progression of atrial fibrillation DOI
Junguo Zhang,

Linna Luo,

Ge Chen

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 951, P. 175710 - 175710

Published: Aug. 23, 2024

Language: Английский

Citations

2
个体臭氧短期暴露与慢性阻塞性肺疾病患者睡眠期间心率的关联及影响因素 DOI Creative Commons

Wenlou Zhang,

Boqi Chen,

Zhaoyong Chen

et al.

Chinese Science Bulletin (Chinese Version), Journal Year: 2024, Volume and Issue: unknown

Published: March 1, 2024

臭氧(Ozone, O3)污染是当前威胁全球人群心血管健康的重要环境因素,然而,O3暴露的早期心血管效应仍不清楚. 人的一生中约1/3的时间在睡眠中度过,研究表明,睡眠期间心率增加是心血管疾病和死亡的关键危险因素. 本研究采用重复测量研究设计,对46名稳定期慢性阻塞性肺疾病(简称慢阻肺)患者开展定期随访,每次随访期间对研究对象的24 h个体O3暴露以及睡眠期间心率进行实时监测,同时收集研究对象的肺功能、呼吸道症状、合并症和睡眠质量信息.采用线性混合效应模型分析个体O3短期暴露与睡眠期间心率的关联,采用交互作用模型探讨潜在的易感因素. 分析结果显示,数分钟的个体O3暴露即与患者睡眠期间心率升高显著相关,在滞后0~8 h效应达到最强,O3浓度每升高19.6 μg/m3,睡眠期间心率增加3.28 (95%CI: 3.12~3.44)次/min. 暴露—反应关系显示,O3浓度超过33 μg/m3时,睡眠期间心率呈现明显的增加趋势. 具有较差的健康状态(包括肺功能更低、呼吸道症状更重、活动受限、不良心理精神状态、合并心血管疾病以及睡眠质量较差)的患者睡眠期间心率更容易受到O3的影响. 上述结果表明O3短期暴露是慢阻肺患者睡眠期间心率加快的重要危险因素,即使在明显低于我国现行空气质量标准的浓度下,仍可观察到O3的不良心血管影响. 本研究可为易感人群心血管疾病的早期防控提供重要科学依据.

Citations

1
Do Antioxidant and Anti-Inflammatory Diets Modify the Association between Air Pollutant Mixture and Cardiometabolic Multimorbidity? DOI

Guzhengyue Zheng,

Aaron M. Qian,

Hui Shi

et al.

Published: Jan. 1, 2024

Language: Английский

Citations

0