Anthocyanin-rich edible flowers, current understanding of a potential new trend in dietary patterns.

Trends in Food Science & Technology, Journal Year: 2023, Volume and Issue: 138, P. 708 - 725

Published: July 20, 2023

Language: Английский

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Effect of Natural Antioxidants from Marigolds (Tagetes erecta L.) on the Oxidative Stability of Soybean Oil

Molecules, Journal Year: 2022, Volume and Issue: 27(9), P. 2865 - 2865

Published: April 30, 2022

In recent years, synthetic antioxidants that are widely used in foods have been shown to cause detrimental health effects, and there has growing interest realised from natural plant extracts. this study, we investigate the potential effects of antioxidant components extracted forage marigold on oxidative stability soybean oil. First, HPLC-Q-TOF-MS/MS was with 1,1-diphenyl-2-picrylhydrazyl (DPPH) screen identify marigold. Four main were identified, including quercetagetin-7-O-glucoside (1), quercetagetin (2), quercetin (3) patuletin (4). Among them, (QG) exhibited highest content strongest DPPH radical scavenging activity effectively inhibited production oxidation products oil during accelerated oxidation, as indicated by reductions peroxide value (PV) acid (AV). Then, fatty acids volatile compounds determined gas chromatography-mass spectrometry (GC-MS) headspace solid-phase microextraction-gas (HS-SPME-GC-MS). A total 108 components, 16 alcohols, 23 aldehydes, 25 ketones, 4 acids, 15 esters, 18 hydrocarbons, 7 other compounds, identified. QG significantly reduced number aldehydes whereas formation hydrocarbons completely prevented. addition, analysis demonstrated unsaturated acids. Consequently, identified a potential, new is believed be safe, effective economical, it may for use extracts feed additives.

Language: Английский

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Extract of Tagetes erecta L., a medicinal plant rich in lutein, promotes gastric healing and reduces ulcer recurrence in rodents

Journal of Ethnopharmacology, Journal Year: 2022, Volume and Issue: 293, P. 115258 - 115258

Published: April 1, 2022

Language: Английский

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Nephroprotective plant species used in traditional Mayan Medicine for renal-associated diseases

Journal of Ethnopharmacology, Journal Year: 2022, Volume and Issue: 301, P. 115755 - 115755

Published: Sept. 29, 2022

Language: Английский

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Protective Role of Rosmarinic Acid in Experimental Urolithiasis: Understanding Its Impact on Renal Parameters

Pharmaceuticals, Journal Year: 2024, Volume and Issue: 17(6), P. 702 - 702

Published: May 29, 2024

This study aimed to assess the ability of rosmarinic acid (RA) prevent kidney stone formation in an ethylene glycol and ammonium chloride (EG/AC) model. There was increase diuresis normotensive (NTRs) hypertensive rats (SHRs) treated with hydrochlorothiazide (HCTZ) exposed EG/AC, while RA restored urine volume NTRs. The EG/AC groups exhibited lower pH electrolyte imbalance; these parameters were not affected by any treatments. Both HCTZ+EG/AC RA+EG/AC reduced calcium oxalate crystal NTR SHR urine. Kidney tissue analysis revealed alterations oxidative stress inflammation all EG/AC-receiving groups, enhancing antioxidant defenses SHRs. Additionally, crystals found histology EG/AC-exposed Bowman’s capsule areas NTRs VEH+EG/AC group showed intense renal damage, others maintained their structures, where treatments HCTZ fundamental for protection Docking that good binding affinity matrix metalloproteinase-9, phosphoethanolamine cytidylyltransferase, human glycolate oxidase enzymes. data disclosed herein underscore importance further research understand underlying mechanisms better validate potential clinical use.

Language: Английский

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Increasing the diversity of marigold (Tagetes sp.) by acute and chronic chemical induced mutation of EMS (Ethyl Methane Sulfonate)

Biodiversitas Journal of Biological Diversity, Journal Year: 2022, Volume and Issue: 23(3)

Published: Feb. 26, 2022

Abstract. Lenawaty DY, Sukma D, Syukur M, Suprapta DN, Nurcholis W, Aisyah SI. 2022. Increasing the diversity of marigold (Tagetes sp.) by acute and chronic chemical induced mutation EMS (Ethyl Methane Sulfonate). Biodiversitas 23: 1399-1407. can be carried out through induction mutations with Ethyl Sulfonate (EMS).This study aims to obtain LC50value, determine sensitivity level plants, plant Tagetes sp.with both acutely chronically. The genetic material used in this was derived from T. erecta genotype MG04 patula MG21. technique performed soaking seeds concentration for 4 hours under 10 different levels (0%, 0.2%, 0.4%, 0.6%, 0.8%, 1.0%, 1.5%, 2.0%, 3.0%). diluting LC501/10x, 1/100x, 1/1000x immersion time 6 hours, 24 48 hours. a Completely Randomized Block Design. Observationswere made on percentage surviving quantitative qualitative characters. data obtained were analyzed using Boxplot ANOVA. results showed that LC50 value is 0.82% LC50of 1.87%, which means treatment quite higher than patula. application method shows relatively low rate limited flower types. produced various shapes whiter color erectaand resulting redder method.

Language: Английский

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Diuretic and Natriuretic Effects of Hesperidin, a Flavanone Glycoside, in Female and Male Hypertensive Rats

Plants, Journal Year: 2022, Volume and Issue: 12(1), P. 25 - 25

Published: Dec. 21, 2022

Hesperidin (HSP) is a major flavanone glycoside in citrus fruits, including sweet oranges and lemons. It demonstrates numerous pharmacological activities, such as antihypertensive effects cardiac kidney tissue protection. However, its effect on modulating renal function has yet to be properly explored. Female male Wistar spontaneously hypertensive rats (SHR) were used test the of HSP function. The divided into different groups, treated orally, placed metabolic cages for urine collection 8 h. HSP, at doses 0.3-3 mg/kg, led an increase volume both female SHR. This was associated with increased Na+ elimination (3 mg/kg) without causing any change K+ excretion or pH conductivity values. When given combination hydrochlorothiazide (HCTZ) amiloride (AMLR), significantly compared group that received only HSP. In relation excretion, depleting HCTZ sparing AMLR prevailed groups. Pre-treatment non-selective cholinergic receptor antagonist, atropine, partially prevented HSP-induced diuresis natriuresis SHR, but this not demonstrated inhibitor enzyme cyclooxygenase, indomethacin. study shows diuretic action rats, activity probably pathway. Although various biological actions have already been defined pioneering research reveals potential medicine.

Language: Английский

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The diuretic effect of ethyl acetate fractions of Artocarpus altilis, Artocarpus champeden, and Artocarpus heterophyllus leaves in normotensive Wistar rats

Journal of Ayurveda and Integrative Medicine, Journal Year: 2023, Volume and Issue: 14(4), P. 100746 - 100746

Published: July 1, 2023

Artocarpus altilis, A. Champeden, and heterophylus are popular species in Indonesia, commonly used as traditional medicine. This study aims to evaluate the diuretic effects of ethyl acetate fraction these three on normotensive Wistar rats. The was prepared by a liquid–liquid extraction method. To effects, sixty rats were divided into normal (distilled water), negative (4.5% NaCl), positive control (furosemide 5 mg/kg), testing groups. groups orally given champeden, at dose levels 25, 50, 100 mg/kg. All animals 4.5% NaCl 2 mL/200 g except group; then drugs according group doses. Urine volume electrolyte produced compared those group. concentration ratio ions calculated determine natriuretic carbonic anhydrase activities. Results: fractions mg/kg more active than standard furosemide (p < 0.05) increase urinary excretion. Furthermore, doses 50 mg/kg, significantly increased excretion Na+, K+, Cl- 0.05). showed good leaves performed Therefore, can be considered potential natural medicines.

Language: Английский

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Terpenoids and phenolic compounds as biologically active compounds of medicinal plants with diuretic effect

Pharmacy & Pharmacology, Journal Year: 2024, Volume and Issue: 11(6), P. 446 - 460

Published: Jan. 30, 2024

The aim of the study was to summarize and systematize literature data, as well results carried out research in field medicinal plants used diuretics Russian Federation abroad. Materials methods . During search for this review article materials, abstract databases PubMed, Google Scholar, ResearchGate elibrary.ru were used. according publications period from 2005 2023. keywords follows: herbal diuretics, diuretic drugs, kidney diseases, types plant raw materials. data authors’ previous scientific on analysis properties certain individual substances a phenolic nature isolated them (simple phenols, flavonoids), also reviewed. Results It determined that activity most used, is due such groups biologically active compounds terpenoids (essential oils saponins), simple flavonoids anthracene derivatives related secondary metabolites. has been shown that, despite fact many have concomitant anti-inflammatory, antimicrobial, antiviral, antihistamine other relevant point view etiology pathogenesis disease, it reasonable use part collections combined preparations, accordance with global trend. materials can be promising source new medicines, examined review. Conclusion make greatest contribution manifestation among which structural diversity noted flavonoids. established composition any drug, taking into account peculiarities both main drug an auxiliary component. expediency using effect preparations treatment urinary tract diseases substantiated.

Language: Английский

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From “traditional” to modern medicine: A medical and historical analysis of Tagetes erecta L. (Cempasúchil)

Journal of Traditional and Complementary Medicine, Journal Year: 2024, Volume and Issue: 15(1), P. 6 - 14

Published: Aug. 5, 2024

The medicinal value of herbal products is often rooted in their "traditional" use, recontextualized by modern biomedical research granting them certain medical uses. Tagetes erecta L. (Asteraceae), native to Mexico, exemplifies such historical developments a species that played key role developing major pharmacologically active compound – lutein. T. (Cempasúchil Nahuatl) has held ritual and importance Mesoamerica was associated with the rain god Tláloc. species' use spans ancient texts varied applications, including treating cold-related ailments promoting menstruation urination. However, Spanish conquest redefined it culturally, medicinally, religiously, mainly as an ornamental flower. discovery lutein marked significant shift, emphasizing its macular health preventing aging-related degeneration. Clinically, trials reveal cognitive, visual, cardiovascular, systemic enhancements, substantiating potential therapeutic benefits. Pharmacologically, demonstrates anti-inflammatory, antiparasitic, anticancer properties. Today, recognized globally for rich carotenoid content. This multifunctional metabolite also used poultry feed supplements. In contemporary culture, cempasúchil, known "flower dead," been adapted ornamental, medicinal, ceremonial, industrial traditional uses pre-Conquest Mexico remain largely unexplored, current applications influenced global research. erecta's evolution beyond dynamic development plant's medicine, well range other spheres daily life.

Language: Английский

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