Bone Mineral Density in Severely Obese Women: Health Risk and Health Protective Risk Factors in Three Different Bone Sites DOI Open Access
Camila Kellen de Souza Cardoso, Maria do Rosário Gondim Peixoto, Ana Paula dos Santos Rodrigues

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2020, Volume and Issue: 17(19), P. 7017 - 7017

Published: Sept. 25, 2020

Factors associated with bone mineral density (BMD) are poorly known in severely obese individuals i.e., a body mass index (BMI) > 35 kg/m2. The objectives of this study were to describe the health profile Brazilian women, identify risk and protective factors for BMD group assess whether these vary according three different sites. was assessed using dual-energy X-ray absorptiometry (DXA). This analyzed baseline data from 104 women who had an average BMI 43.7 ± 4.5 kg/m2 presented following status: 1.283 0.094 g/cm2 total body, 1.062 0.159 vertebral column 1.195 0.134 hip. They took part "Effect nutritional intervention olive oil severe obesity" randomized clinical trial (DieTBra Trial). negatively lower age ≥50 years sites Smoking (p = 0.045); ≥ 50kg/m2 hip; menopause high C-reactive protein (CRP) levels 0.049), insufficient zinc 0.010) previous fracture 0.007). positively physical activity (≥150 min/week 0.001)) type 2 diabetes mellitus (DM2) < 0.0001) adequate vitamin D food consumption 0.039) column. A 50 factor BMD. findings showed that varied by site. original is registered ClinicalTrials.gov. (protocol number: NCT02463435).

Language: Английский

Prevalence of constipation in adults with obesity class II and III and associated factors DOI Creative Commons
Érika Aparecida Silveira, Annelisa Silva e Alves de Carvalho Santos,

Jessivane Nascimento Ribeiro

et al.

BMC Gastroenterology, Journal Year: 2021, Volume and Issue: 21(1)

Published: May 12, 2021

Constipation and obesity have common risk factors. However, little is known about the occurrence of constipation in individuals with severe associated

Language: Английский

Citations

62
Risk Factors Associated with Cardiac Autonomic Modulation in Obese Individuals DOI Creative Commons

Camila Ferreira de Oliveira,

Érika Aparecida Silveira,

Lorena Pereira Souza Rosa

et al.

Journal of Obesity, Journal Year: 2020, Volume and Issue: 2020, P. 1 - 8

Published: April 1, 2020

Obesity leads to an imbalance in the autonomic nervous system, especially increased sympathetic modulation and decreased vagal tone, some anthropometric, metabolic, lifestyle variables may increase risk of developing cardiovascular disease. Objective. To analyze association between biochemical anthropometric markers, food intake, physical activity level severely obese individuals. Methodology. The present study is a cutout randomized clinical trial "Effect nutritional intervention olive oil severe obesity" (DieTBra Trial), where baseline data were analyzed. Anthropometric data, exams, heart rate variability (HRV), accelerometry, 24 h recall (R24H) patients (body mass index BMI ≥35 kg/m2) collected. Results. 64 analyzed, with mean age 39.10 ± 7.74 years (27 58 years). By HRV analysis, frequency domain, had higher predominance (low (LF) 56.44 20.31 nu) lower parasympathetic (high (HF) 42.52 19.18 nu). A negative was observed Homeostasis Evaluation Model (HOMA-IR) HF (p = 0.049). In there moderate vigorous component 0.043), for sedentary time (ST), 0.049) LF/HF 0.036) positive LF 0.014). For multiple linear regression, waist circumference (WC) HOMA-IR values negatively associated (β -0.685, p 0.010; β -14.989, respectively). 0.141, 0.003) percentage lipids ingested -0.030, 0.043) LF/HF. Conclusion. Among studied, insulin resistance central adiposity showed greatest influence on cardiac obese, increasing

Language: Английский

Citations

36
High prevalence of musculoskeletal pain in individuals with severe obesity: sites, intensity, and associated factors DOI Creative Commons
Carolina Rodrigues Mendonça, Mark A. Noll, Annelisa Silva e Alves de Carvalho Santos

et al.

The Korean journal of pain, Journal Year: 2020, Volume and Issue: 33(3), P. 245 - 257

Published: July 1, 2020

Background: Musculoskeletal pain is associated with obesity; however, information on factors in adults obesity and severe limited.The purpose of this study was to assess the prevalence musculoskeletal by site intensity individuals (body mass index ≥ 35.0 kg/m 2 ).Methods: Baseline data from DieTBra Trial evaluating symptoms nine body regions over last seven days using Nordic Questionnaire Symptoms Numerical Pain Scale.The variables analyzed multiple Poisson regression hierarchical analysis were: sociodemographic, lifestyle, food consumption, clinical, anthropometric, outcome moderate intense pain.Results: In 150 participants, there a high ankle foot (68.7%), lower back (62.7%), knees (53.3%) upper (52.0%), predominance pain.Factors according specific sites type diabetes hand/wrist pain; sedentary time hip insomnia knee; edema limbs ankles/feet; degree ankle/foot percentage total fat pain.Conclusions: There an association clinical variables, obesity, lifestyle.

Language: Английский

Citations

30
Type 2 Diabetes Mellitus in Class II and III Obesity: Prevalence, Associated Factors, and Correlation between Glycemic Parameters and Body Mass Index DOI Open Access
Érika Aparecida Silveira, Lorena Pereira de Souza Rosa, Annelisa Silva e Alves de Carvalho Santos

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2020, Volume and Issue: 17(11), P. 3930 - 3930

Published: June 2, 2020

Despite the worldwide growth of class II and III obesity, factors associated with type 2 diabetes mellitus (T2DM) in these obese individuals are not widely understood. Moreover, no study has investigated associations South America. Our aimed to investigate prevalence T2DM its factors, an emphasis on biochemical parameters eating habits, individuals. We also analyze correlation between glycemic body mass index (BMI). Baseline data from a randomized clinical trial (DieTBra Trial) 150 (BMI > 35 kg/m

Language: Английский

Citations

29
Cardiovascular disease risk prediction by Framingham risk score in women with polycystic ovary syndrome DOI Creative Commons
Mina Amiri, Maryam Mousavi, Mahsa Noroozzadeh

et al.

Reproductive Biology and Endocrinology, Journal Year: 2025, Volume and Issue: 23(1)

Published: Feb. 4, 2025

Language: Английский

Citations

0
Effects of Extra Virgin Olive Oil (EVOO) and the Traditional Brazilian Diet on Sarcopenia in Severe Obesity: A Randomized Clinical Trial DOI Open Access
Érika Aparecida Silveira, Jacqueline Danésio de Souza, Ana Paula dos Santos Rodrigues

et al.

Nutrients, Journal Year: 2020, Volume and Issue: 12(5), P. 1498 - 1498

Published: May 21, 2020

Nutritional interventions may have positive effects on sarcopenia and body composition.to evaluate the effectiveness of extra virgin olive oil (EVOO) consumption a healthy traditional Brazilian diet (DieTBra) improving indicators reducing total fat in severe obesity.A randomized controlled trial registered at ClinicalTrials.gov (NCT02463435) conducted with 111 severely obese participants into three treatment groups-(1) EVOO (52 mL/day), (2) DieTBra, (3) DieTBra + mL/day)-for 12 weeks. Body composition was assessed by dual-energy X-ray absorptiometry walking speed handgrip strength.Significant reductions (p = 0.041) weight 0.003) were observed group. In DietBra group there also significant reduction (0.001) compared to oil-only ANCOVA analyses showed 0.016) 0.004) groups. Individuals had improvements their 0.042) strength 0.044).DieTBra contributes strength, speed, adults. The major study (NCT02463435).

Language: Английский

Citations

23
Effect of Extra Virgin Olive Oil and Traditional Brazilian Diet on the Bone Health Parameters of Severely Obese Adults: A Randomized Controlled Trial DOI Open Access
Camila Kellen de Souza Cardoso, Annelisa Silva e Alves de Carvalho Santos, Lorena Pereira de Souza Rosa

et al.

Nutrients, Journal Year: 2020, Volume and Issue: 12(2), P. 403 - 403

Published: Feb. 4, 2020

Dietary interventions can stabilize and/or reverse bone mass loss. However, there are no reports on its effects mineral density (BMD) in severely obese people, despite the vulnerability of this group to We examine effect extra virgin olive oil supplementation and traditional Brazilian diet (DieTBra) BMD levels calcium, vitamin D, parathyroid hormone (PTH) adults. A randomized controlled trial followed-up with adults (n = 111, mean body index 43.6 kg/m2 ± 4.5 kg/m2) for 12 weeks. Study participants received either (52 mL/day), DieTBra, or + DieTBra mL/day DieTBra). was assessed by total spine hip dual-energy X-ray absorptiometry. After interventions, means (p 0.016) 0.029) were higher than group. Final calcium compared 0.026). Findings suggest that have positive health The major study registered at ClinicalTrials.gov (NCT02463435).

Language: Английский

Citations

22
Range of adiposity and cardiorenal syndrome DOI Open Access

Fernando Pazos

World Journal of Diabetes, Journal Year: 2020, Volume and Issue: 11(8), P. 322 - 350

Published: Aug. 13, 2020

Obesity and obesity-related co-morbidities, diabetes mellitus, hypertension are among the fastest-growing risk factors of heart failure kidney disease worldwide. Obesity, which is not a unitary concept, or static process, ranges from alterations in distribution to amount adiposity. Visceral adiposity, includes intraabdominal visceral fat mass ectopic deposition such as hepatic, cardiac, renal, was robustly associated with greater for cardiorenal morbidity than subcutaneous In addition, morbid obesity has also demonstrated negative effect on cardiac renal functioning. The mechanisms by adipose tissue linked syndrome (CRS) hemodynamic mechanical changes, well neurohumoral pathways insulin resistance, endothelial dysfunction, nitric oxide bioavailability, renin-angiotensin-aldosterone, oxidative stress, sympathetic nervous systems, natriuretic peptides, adipokines inflammation. Adiposity other co-morbidities induce adverse remodeling interstitial fibrosis. Heart preserved ejection fraction been functional structural abnormalities. might impair function through hyperfiltration, increased glomerular capillary wall tension, podocyte leads tubulointerstitial fibrosis loss nephrons and, finally, chronic disease. development new treatments effects context type 2 diabetes, improves mortality outcome, highlighted importance CRS its prevalence. Increased body triggers cellular, neuro-humoral metabolic pathways, create phenotype specific cellular biochemical biomarkers. become single umbrella syndrome. This review article provides clinical overview available data relationship between range adiposity CRS, support umbrella, most relevant studies recent therapeutic approaches.

Language: Английский

Citations

21
Bariatric surgery and cardiovascular outcome DOI Creative Commons
Waleed Ammar,

H Basset,

Amr AL Faramawy

et al.

The Egyptian Heart Journal, Journal Year: 2020, Volume and Issue: 72(1)

Published: Oct. 2, 2020

Abstract Background Obesity is recognized as a classic risk factor for atherosclerosis and subsequent cardiovascular disease (CVD). Weight loss after bariatric surgery has been associated with reduced CV mortality total in obese patients. Our aim was to study the impact of on profile, cardiac structure, function postoperatively. Results This prospective longitudinal included 100 morbidly patients at final analysis. All were subjected full clinical, laboratory, echocardiographic examination baseline 6 months surgery. The mean age population 37.2 ± 10.49 BMI 47 6.82. Females represented 84%. Sleeve gastrectomy Roux-en-Y gastric bypass performed 79% 21%, respectively. Surgery-related morbidity 0.94% 4.7%, After months, there significant decreases BMI, heart rate, SBP, DBP, Framingham score ( P < 0.0001). prevalence factors decreased follows: hypertension 24% vs. 12%, = 0.0005; DM 21% 11%, 0.002; dyslipidemia 32% 7%, 0.0001; metabolic syndrome 54% 26%, 0.0001. Highly 0.0001) decrease fasting PG 2 h PP-PG, HbA1c, ASL, ALT, cholesterol, LDL, TG, increase HDL observed There shortening QTc interval 0.009), LV dimensions mass index 0.0001), EF% 0.0003). follow-up showed positive correlation age, score, preoperative r 0.289, 0.0036; 0.37, 0.0054; 0.31, 0.0081, respectively). Conclusion In addition enabling achieve substantial weight loss, provides myriad health benefits. reduction favorable improvement function.

Language: Английский

Citations

20
Serum and Dietary Vitamin D in Individuals with Class II and III Obesity: Prevalence and Association with Metabolic Syndrome DOI Open Access
Érika Aparecida Silveira, Camila Kellen de Souza Cardoso, Letícia de Almeida Nogueira e Moura

et al.

Nutrients, Journal Year: 2021, Volume and Issue: 13(7), P. 2138 - 2138

Published: June 22, 2021

The association between vitamin D deficiency and metabolic syndrome (MS) in severe obesity is unclear controversial. We analyzed serum dietary their with MS 150 adults class II III (BMI ≥ 35 kg/m2) from the DieTBra Trial (NCT02463435). parameters were high fasting blood glucose, low HDL cholesterol, triglycerides, elevated waist circumference, hypertension. Vitamin was considered as a level < 20 ng/mL. performed multivariate Poisson regression adjusted for sociodemographic lifestyle variables. prevalence of 13.3% (mean 29.9 ± 9.4 ng/mL) median 51.3 IU/day. There no significant associations D, serum, diet variables, lifestyle, obesity. Serum associated age 50 years (p = 0.034). After fully regression, its not or except lower HDL, which (PR 0.71, 95% CI 0.52-0.97; p 0.029). Severe obese individuals had deficiency, MS.

Language: Английский

Citations

17