Biomimetic nanocarriers: integrating natural functions for advanced therapeutic applications DOI Creative Commons
Hugo Félix Perini, Beatriz Sodré Matos, Carlo José Freire Oliveira

et al.

Beilstein Journal of Nanotechnology, Journal Year: 2024, Volume and Issue: 15, P. 1619 - 1626

Published: Dec. 16, 2024

Biomimetic nanocarriers, engineered to mimic the characteristics of native cells, offer a revolutionary approach in treatment various complex human diseases. This strategy enhances drug delivery by leveraging innate properties cellular components, thereby improving biocompatibility and targeting specificity. nanocarriers demonstrate significant advancements systems against cancer therapy, Alzheimer's disease, autoimmune diseases, viral infections such as COVID-19. Here, we address therapeutic applications biomimetic their promising for personalized medicine.

Language: Английский

Recent advances in biomimetic cell membrane–camouflaged nanoparticles for cancer therapy DOI Creative Commons
Sajjad Alimohammadvand,

Masoumeh Kaveh Zenjanab,

Milad Mashinchian

et al.

Biomedicine & Pharmacotherapy, Journal Year: 2024, Volume and Issue: 177, P. 116951 - 116951

Published: June 19, 2024

The emerging strategy of biomimetic nanoparticles (NPs) via cellular membrane camouflage holds great promise in cancer therapy. This scholarly review explores the utilization membranes derived from diverse entities; blood cells, immune stem and bacterial cells as examples NP coatings. camouflaging endows NPs with nuanced tumor-targeting abilities such self-recognition, homotypic targeting, long-lasting circulation, thus also improving tumor therapy efficacy overall. comprehensive examination encompasses a variety cell camouflaged (CMCNPs), elucidating their underlying targeted mechanisms delineating strategies for anti-cancer applications. Furthermore, systematically presents synthesis source materials methodologies employed order to construct characterize these CMCNPs, specific emphasis on use treatment.

Language: Английский

Citations

15

Paclitaxel for breast cancer therapy: A review on effective drug combination modalities and nano drug delivery platforms DOI

Masoumeh Kaveh Zenjanab,

Sajjad Alimohammadvand, Abolfazl Doustmihan

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 95, P. 105567 - 105567

Published: March 19, 2024

Language: Английский

Citations

13

Applications of dielectrophoresis in microfluidic-based exosome separation and detection DOI
Lan Mei, Fang Yang

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 491, P. 152067 - 152067

Published: May 9, 2024

Language: Английский

Citations

10

Beyond Chemotherapy: Exploring 5-FU Resistance and Stemness in Colorectal Cancer DOI
Urmila Singh, Rekha Rani Kokkanti,

Srinivas Patnaik

et al.

European Journal of Pharmacology, Journal Year: 2025, Volume and Issue: unknown, P. 177294 - 177294

Published: Jan. 1, 2025

Language: Английский

Citations

1

Recent advances and future prospects of engineered exosomes as advanced drug and gene delivery systems DOI
Waleed Y. Rizg, Majed Alghamdi, Sherif El Saadany

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: 106, P. 106696 - 106696

Published: Feb. 6, 2025

Language: Английский

Citations

1

Exosome isolation and characterization for advanced diagnostic and therapeutic applications DOI Creative Commons
Nobendu Mukerjee, Arghya Bhattacharya, Swastika Maitra

et al.

Materials Today Bio, Journal Year: 2025, Volume and Issue: 31, P. 101613 - 101613

Published: Feb. 25, 2025

Language: Английский

Citations

1

Non-invasive blood tests for earlier diagnosis and treatment of endometriosis DOI
Behnaz Sadeghzadeh Oskouei, Zahra Sadat Asadi, Rana Jahanban‐Esfahlan

et al.

Journal of Reproductive Immunology, Journal Year: 2025, Volume and Issue: unknown, P. 104521 - 104521

Published: March 1, 2025

Language: Английский

Citations

1

Molecular insights to therapeutic in cancer: role of exosomes in tumor microenvironment, metastatic progression and drug resistance DOI

Shikshya S. Panda,

Rajeev Kumar Sahoo,

Sambit K. Patra

et al.

Drug Discovery Today, Journal Year: 2024, Volume and Issue: 29(8), P. 104061 - 104061

Published: June 18, 2024

Language: Английский

Citations

6

Notch Signaling Suppression by Golden Phytochemicals: Potential for Cancer Therapy DOI Creative Commons
Masoumeh Kaveh Zenjanab, Nastaran Hashemzadeh, Sajjad Alimohammadvand

et al.

Advanced Pharmaceutical Bulletin, Journal Year: 2024, Volume and Issue: 14(2), P. 302 - 313

Published: March 10, 2024

Cancer is one of the main causes mortality worldwide. cells are characterized by unregulated cellular processes, including proliferation, progression, and angiogenesis. The occurrence these processes due to dysregulation various signaling pathways such as NF-κB (nuclear factor-κB), Wnt/beta-catenin, Notch MAPK (mitogen-activated protein kinases). cause progression types malignant tumors. Among phytochemicals for cancer therapy, several have attracted great interest, curcumin, genistein, quercetin, silibinin, resveratrol, cucurbitacin glycyrrhizin. Given molecular heterogeneity within tumors high toxicity side effects synthetic chemotherapeutics, natural products with pleiotropic that simultaneously target numerous appear be ideal substitutes therapy. With this in mind, we take a look at current status, impact potential known compounds golden on key tumors, focusing pathway. This review may useful discovering new targets safe efficient therapy chemotherapeutics.

Language: Английский

Citations

4

Exosomal biomarkers: A novel frontier in the diagnosis of gastrointestinal cancers DOI
Yuan Zhang,

Ning-Ning Yue,

Liyu Chen

et al.

World Journal of Gastrointestinal Oncology, Journal Year: 2025, Volume and Issue: 17(4)

Published: March 24, 2025

Gastrointestinal (GI) cancers, which predominantly manifest in the stomach, colorectum, liver, esophagus, and pancreas, accounting for approximately 35% of global cancer-related mortality. The advent liquid biopsy has introduced a pivotal diagnostic modality early identification premalignant GI lesions incipient cancers. This non-invasive technique not only facilitates prompt therapeutic intervention, but also serves as critical adjunct prognosticating likelihood tumor recurrence. wealth circulating exosomes present body fluids is often enriched with proteins, lipids, microRNAs, other RNAs derived from cells. These specific cargo components are reflective processes involved tumorigenesis, progression, response to treatment. As such, they represent group promising biomarkers aiding diagnosis cancer. In this review, we delivered an exhaustive overview composition pathways sorting within these vesicles. We laid out some clinical evidence that supported utilization cancers discussed their potential application. Furthermore, addressed challenges encountered when harnessing predictive instruments realm

Language: Английский

Citations

0