Beilstein Journal of Nanotechnology,
Journal Year:
2024,
Volume and Issue:
15, P. 1619 - 1626
Published: Dec. 16, 2024
Biomimetic
nanocarriers,
engineered
to
mimic
the
characteristics
of
native
cells,
offer
a
revolutionary
approach
in
treatment
various
complex
human
diseases.
This
strategy
enhances
drug
delivery
by
leveraging
innate
properties
cellular
components,
thereby
improving
biocompatibility
and
targeting
specificity.
nanocarriers
demonstrate
significant
advancements
systems
against
cancer
therapy,
Alzheimer's
disease,
autoimmune
diseases,
viral
infections
such
as
COVID-19.
Here,
we
address
therapeutic
applications
biomimetic
their
promising
for
personalized
medicine.
Biomedicine & Pharmacotherapy,
Journal Year:
2024,
Volume and Issue:
177, P. 116951 - 116951
Published: June 19, 2024
The
emerging
strategy
of
biomimetic
nanoparticles
(NPs)
via
cellular
membrane
camouflage
holds
great
promise
in
cancer
therapy.
This
scholarly
review
explores
the
utilization
membranes
derived
from
diverse
entities;
blood
cells,
immune
stem
and
bacterial
cells
as
examples
NP
coatings.
camouflaging
endows
NPs
with
nuanced
tumor-targeting
abilities
such
self-recognition,
homotypic
targeting,
long-lasting
circulation,
thus
also
improving
tumor
therapy
efficacy
overall.
comprehensive
examination
encompasses
a
variety
cell
camouflaged
(CMCNPs),
elucidating
their
underlying
targeted
mechanisms
delineating
strategies
for
anti-cancer
applications.
Furthermore,
systematically
presents
synthesis
source
materials
methodologies
employed
order
to
construct
characterize
these
CMCNPs,
specific
emphasis
on
use
treatment.
Advanced Pharmaceutical Bulletin,
Journal Year:
2024,
Volume and Issue:
14(2), P. 302 - 313
Published: March 10, 2024
Cancer
is
one
of
the
main
causes
mortality
worldwide.
cells
are
characterized
by
unregulated
cellular
processes,
including
proliferation,
progression,
and
angiogenesis.
The
occurrence
these
processes
due
to
dysregulation
various
signaling
pathways
such
as
NF-κB
(nuclear
factor-κB),
Wnt/beta-catenin,
Notch
MAPK
(mitogen-activated
protein
kinases).
cause
progression
types
malignant
tumors.
Among
phytochemicals
for
cancer
therapy,
several
have
attracted
great
interest,
curcumin,
genistein,
quercetin,
silibinin,
resveratrol,
cucurbitacin
glycyrrhizin.
Given
molecular
heterogeneity
within
tumors
high
toxicity
side
effects
synthetic
chemotherapeutics,
natural
products
with
pleiotropic
that
simultaneously
target
numerous
appear
be
ideal
substitutes
therapy.
With
this
in
mind,
we
take
a
look
at
current
status,
impact
potential
known
compounds
golden
on
key
tumors,
focusing
pathway.
This
review
may
useful
discovering
new
targets
safe
efficient
therapy
chemotherapeutics.
World Journal of Gastrointestinal Oncology,
Journal Year:
2025,
Volume and Issue:
17(4)
Published: March 24, 2025
Gastrointestinal
(GI)
cancers,
which
predominantly
manifest
in
the
stomach,
colorectum,
liver,
esophagus,
and
pancreas,
accounting
for
approximately
35%
of
global
cancer-related
mortality.
The
advent
liquid
biopsy
has
introduced
a
pivotal
diagnostic
modality
early
identification
premalignant
GI
lesions
incipient
cancers.
This
non-invasive
technique
not
only
facilitates
prompt
therapeutic
intervention,
but
also
serves
as
critical
adjunct
prognosticating
likelihood
tumor
recurrence.
wealth
circulating
exosomes
present
body
fluids
is
often
enriched
with
proteins,
lipids,
microRNAs,
other
RNAs
derived
from
cells.
These
specific
cargo
components
are
reflective
processes
involved
tumorigenesis,
progression,
response
to
treatment.
As
such,
they
represent
group
promising
biomarkers
aiding
diagnosis
cancer.
In
this
review,
we
delivered
an
exhaustive
overview
composition
pathways
sorting
within
these
vesicles.
We
laid
out
some
clinical
evidence
that
supported
utilization
cancers
discussed
their
potential
application.
Furthermore,
addressed
challenges
encountered
when
harnessing
predictive
instruments
realm