Predicting the effects of degradation on viscoelastic relaxation time using model transient networks DOI Creative Commons

Ryunosuke Kobayashi,

Mitsuru Naito, Kanjiro Miyata

et al.

Polymer Journal, Journal Year: 2024, Volume and Issue: 56(7), P. 685 - 691

Published: March 5, 2024

Abstract In this study, we utilized tetra-armed polyethylene glycol (Tetra-PEG) slimes, which are model transient networks with well-controlled structures, to predict the effects of long-term degradation on viscoelastic properties liquids. Viscoelastic liquids, such as sodium hyaluronate, frequently used in biomedical applications within human body. However, precisely controlling these liquids is challenging, main chains undergo stochastic degradation. To establish a predictable for studying effects, employed Tetra-PEG slime, and modifications were performed introduce specific cleavage sites areas connections. The slimes characterized by single relaxation modes, modes independent from degree degradation, was determined hydrolyzing sites. Overall, work provides universal design precisely-controllable

Language: Английский

Advancements in 3D-printable polysaccharides, proteins, and synthetic polymers for wound dressing and skin scaffolding – A review DOI
Ali Sadeghianmaryan,

Nivad Ahmadian,

Sydney Wheatley

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 266, P. 131207 - 131207

Published: March 28, 2024

Language: Английский

Citations

24

Silk fibroin-based scaffolds for wound healing applications with metal oxide nanoparticles DOI Creative Commons
Denisa-Maria Radulescu, Ecaterina Andronescu, Otilia Ruxandra Vasile

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 96, P. 105689 - 105689

Published: April 21, 2024

In the last few years, wound healing and development of "ideal" biomaterials that provide quick recovery minimize scarring have represented one most important priorities researchers. this direction, silk fibroin (SF) scaffolds gained substantial awareness, as a promising polymer owing to their increased biocompatibility, outstanding mechanical properties, biodegradability, especially tensile strength. Furthermore, SF is acknowledged accelerate process by encouraging cell growth proliferation, also migration different types cells are included in stages process. Therefore, metal oxide nanoparticles (NPs), such iron (FeO), copper (CuO), zinc (ZnO), or magnesium (MgO) NPs, been extensively researched for antimicrobial properties ability enhance tissue regeneration addition SF. When introduced within scaffolds, these NPs impart enhanced including improved scaffold stability durability. Moreover, presence could increase biocompatibility facilitating adhesion, migration, ultimately promoting processes. The incorporation other natural polymers into has thus emerged favorable method therapeutic potential developed biomaterial. This review aims an overview advancements containing applications.

Language: Английский

Citations

14

Biopolymer-based hydrogels for biomedical applications: Bioactivity and wound healing properties DOI
Fariba Mehvari, Vahid Ramezanzade, Jusung An

et al.

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 518, P. 216093 - 216093

Published: July 25, 2024

Language: Английский

Citations

12

Advances in Smart Hybrid Scaffolds: A Strategic Approach for Regenerative Clinical Applications DOI Creative Commons
Ahsan Riaz Khan,

Amol D. Gholap,

Navdeep Singh Grewal

et al.

Engineered Regeneration, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

Citations

1

Silver Nanoparticles in 3D Printing: A New Frontier in Wound Healing DOI Creative Commons

Mohammad Ebrahim Astaneh,

Narges Fereydouni

ACS Omega, Journal Year: 2024, Volume and Issue: 9(40), P. 41107 - 41129

Published: Sept. 16, 2024

This review examines the convergence of silver nanoparticles (AgNPs), three-dimensional (3D) printing, and wound healing, focusing on significant advancements in these fields. We explore unique properties AgNPs, notably their strong antibacterial efficacy potential applications enhancing recovery. Furthermore, delves into 3D printing technology, discussing its core principles, various materials employed, recent innovations. The integration AgNPs 3D-printed structures for regenerative medicine is analyzed, emphasizing benefits this combined approach identifying challenges that must be addressed. comprehensive overview aims to elucidate current state field direct future research toward developing more effective solutions healing.

Language: Английский

Citations

6

The Printed Path to Healing: Advancing Wound Dressings through Additive Manufacturing DOI Open Access
Joana Duarte, Ana P. Piedade, Bruno Sarmento

et al.

Advanced Healthcare Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 5, 2025

Abstract Wound care challenges healthcare systems worldwide as traditional dressings often fall short in addressing the diverse and complex nature of wound healing. Given conventional treatments limitations, innovative alternatives are urgent. Additive manufacturing (AM) has emerged a distinct transformative approach for developing advanced dressings, offering unprecedented functionality customization. Besides exploring AM processes state‐of‐the‐art, this review comprehensively examines application to produce cellular‐compatible bioactive, therapeutic agent delivery, patient‐centric, responsive dressings. This distinguishes itself from published literature by covering variety types summarizing important data, including used materials, process/technology, printing parameters, findings vitro, ex vivo, vivo studies. The prospects enhancing healing outcomes also analyzed translational cost‐effective manner.

Language: Английский

Citations

0

3D printed therapeutic scaffolds for wound healing applications DOI
Sofía Municoy, Pablo Edmundo Antezana,

Sofía Genovés

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 207 - 226

Published: Jan. 1, 2025

Language: Английский

Citations

0

Nanotherapeutics-impregnated medical devices and their regulatory aspects DOI
Shikha Baghel Chauhan,

Charinya Chankhampan,

Indu Singh

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 41 - 61

Published: Jan. 1, 2025

Language: Английский

Citations

0

Pharmaceutical 3D Printing Technology Integrating Nanomaterials and Nanodevices for Precision Neurological Therapies DOI Creative Commons
Jurga Bernatonienė,

Mindaugas Plieskis,

Kęstutis Petrikonis

et al.

Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(3), P. 352 - 352

Published: March 9, 2025

Pharmaceutical 3D printing, combined with nanomaterials and nanodevices, presents a transformative approach to precision medicine for treating neurological diseases. This technology enables the creation of tailored dosage forms controlled release profiles, enhancing drug delivery across blood−brain barrier (BBB). The integration nanoparticles, such as poly lactic-co-glycolic acid (PLGA), chitosan, metallic nanomaterials, into 3D-printed scaffolds improves treatment efficacy by providing targeted prolonged release. Recent advances have demonstrated potential these systems in conditions like Parkinson’s disease, epilepsy, brain tumors. Moreover, printing allows multi-drug combinations personalized formulations that adapt individual patient needs. Novel approaches, including stimuli-responsive systems, on-demand dosing, theragnostics, provide new possibilities real-time monitoring disorders. Despite innovations, challenges remain terms scalability, regulatory approval, long-term safety. future perspectives this suggest its revolutionize treatments offering patient-specific therapies, improved penetration, enhanced outcomes. review discusses current state, applications, nanotechnology treatment, highlighting need further research overcome existing challenges.

Language: Английский

Citations

0

Advancing Burn Care: The Role of 3D Printing in Advanced Dressing Development DOI

Michael Nycz,

Iga Litwinska-Inglot,

Maria Partyka

et al.

Dermatologic Surgery, Journal Year: 2025, Volume and Issue: unknown

Published: March 11, 2025

BACKGROUND The high mortality rate and long treatment time for burns require the development of new effective therapies. OBJECTIVE study aims to systematically review current research on 3D printing technologies developing advanced burn dressings, identifying existing challenges exploring potential clinical integration. MATERIALS AND METHODS This systematic examines 45 studies from 2018 2023 dressings identify perspectives. RESULTS highlights significant advancements in using create customized tailored patients' anatomy. Technologies such as stereolithography, extrusion printing, bioprinting ensure precise functional bandages. Biocompatible materials, including synthetic polymers natural hydrogels, promote tissue regeneration lower infection risks. Bioprinting's integration living cells further enhances regenerative medicine possibilities. Clinical data indicate that 3D-printed improve wound healing, reduce pain inflammation, yield better aesthetic outcomes. CONCLUSION confirms personalized burns.

Language: Английский

Citations

0