Acute exposure to 17-α-ethinylestradiol disrupt the embryonic development and oxidative status of Danio rerio DOI

María del Carmen Ramírez-Montero,

Leobardo Manuel Gómez‐Oliván,

Verónica Margarita Gutiérrez-Noya

et al.

Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology, Journal Year: 2021, Volume and Issue: 251, P. 109199 - 109199

Published: Oct. 2, 2021

Language: Английский

Metformin Contamination in Global Waters: Biotic and Abiotic Transformation, Byproduct Generation and Toxicity, and Evaluation as a Pharmaceutical Indicator DOI
Yuanzhen He, Yanyan Zhang, Feng Ju

et al.

Environmental Science & Technology, Journal Year: 2022, Volume and Issue: 56(19), P. 13528 - 13545

Published: Sept. 15, 2022

Metformin is the first-line antidiabetic drug and one of most prescribed medications worldwide. Because its ubiquitous occurrence in global waters demonstrated ecotoxicity, metformin, as with other pharmaceuticals, has become a concerning emerging contaminant. subject to transformation, producing numerous problematic transformation byproducts (TPs). The occurrence, removal, toxicity metformin have been continually reviewed; yet, comprehensive analysis pathways, byproduct generation, associated change adverse effects lacking. In this review, we provide critical overview fate during water treatments natural processes compile 32 organic TPs generated from biotic abiotic pathways. These occur aquatic systems worldwide along metformin. Enhanced several compared through organism tests necessitates development complete mineralization techniques for more attention on TP monitoring. We also assess potential indicate overall contamination pharmaceuticals environments, previously acknowledged ones, found be robust or comparable indicator such pharmaceutical contamination. addition, insightful avenues future research

Language: Английский

Citations

44
Zebrafish: an important model for understanding scoliosis DOI Open Access
Haibo Xie, Mingzhu Li,

Yunsi Kang

et al.

Cellular and Molecular Life Sciences, Journal Year: 2022, Volume and Issue: 79(9)

Published: Sept. 1, 2022

Language: Английский

Citations

28
Brain damage induced by contaminants released in a hospital from Mexico: Evaluation of swimming behavior, oxidative stress, and acetylcholinesterase in zebrafish (Danio rerio) DOI

Karina Elisa Rosales-Pérez,

Gustavo Axel Elizalde-Velázquez, Leobardo Manuel Gómez‐Oliván

et al.

Chemosphere, Journal Year: 2022, Volume and Issue: 294, P. 133791 - 133791

Published: Jan. 29, 2022

Language: Английский

Citations

23
Low concentrations of ciprofloxacin alone and in combination with paracetamol induce oxidative stress, upregulation of apoptotic-related genes, histological alterations in the liver, and genotoxicity in Danio rerio DOI
Gustavo Axel Elizalde-Velázquez,

Jonathan Ricardo Rosas-Ramírez,

Demetrio Raldúa

et al.

Chemosphere, Journal Year: 2022, Volume and Issue: 294, P. 133667 - 133667

Published: Jan. 22, 2022

Language: Английский

Citations

22
Chronic exposure to environmentally relevant concentrations of guanylurea induces neurotoxicity of Danio rerio adults DOI
Gustavo Axel Elizalde-Velázquez, Leobardo Manuel Gómez‐Oliván,

Karina Elisa Rosales-Pérez

et al.

The Science of The Total Environment, Journal Year: 2022, Volume and Issue: 819, P. 153095 - 153095

Published: Jan. 14, 2022

Language: Английский

Citations

21
Chronic exposure to realistic concentrations of metformin prompts a neurotoxic response in Danio rerio adults DOI
Gustavo Axel Elizalde-Velázquez, Leobardo Manuel Gómez‐Oliván, Sandra García-Medina

et al.

The Science of The Total Environment, Journal Year: 2022, Volume and Issue: 849, P. 157888 - 157888

Published: Aug. 9, 2022

Language: Английский

Citations

21
Multiclass target analysis of contaminants of emerging concern including transformation products, soil bioavailability assessment and retrospective screening as tools to evaluate risks associated with reclaimed water reuse DOI
Vasiliki G. Beretsou, Maria‐Christina Nika, Kyriakos Manoli

et al.

The Science of The Total Environment, Journal Year: 2022, Volume and Issue: 852, P. 158391 - 158391

Published: Aug. 29, 2022

Language: Английский

Citations

21
Influence of sucralose, acesulfame-k, and their mixture on brain's fish: A study of behavior, oxidative damage, and acetylcholinesterase activity in Danio rerio DOI

Karla Colín-García,

Gustavo Axel Elizalde-Velázquez, Leobardo Manuel Gómez‐Oliván

et al.

Chemosphere, Journal Year: 2023, Volume and Issue: 340, P. 139928 - 139928

Published: Aug. 23, 2023

Language: Английский

Citations

11
Teratogenic effects induced by paracetamol, ciprofloxacin, and their mixture on Danio rerio embryos: Oxidative stress implications DOI

Jonathan Ricardo Rosas-Ramírez,

José Manuel Orozco-Hernández, Gustavo Axel Elizalde-Velázquez

et al.

The Science of The Total Environment, Journal Year: 2021, Volume and Issue: 806, P. 150541 - 150541

Published: Sept. 27, 2021

Language: Английский

Citations

26
The elevated toxicity of the biodegradation product (guanylurea) from metformin and the antagonistic pattern recognition of combined toxicity: Insight from the pharmaceutical risk assessment and the simulated wastewater treatment DOI
Fan Gao, Hao Wen, Sen Feng

et al.

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 892, P. 164747 - 164747

Published: June 7, 2023

Language: Английский

Citations

10