Pathogen detection with electrochemical biosensors: Advantages, challenges and future perspectives

Journal of Electroanalytical Chemistry, Journal Year: 2021, Volume and Issue: 882, P. 114989 - 114989

Published: Jan. 12, 2021

Language: Английский

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Ultrasensitive multichannel immunochromatographic assay for rapid detection of foodborne bacteria based on two-dimensional film-like SERS labels

Journal of Hazardous Materials, Journal Year: 2022, Volume and Issue: 437, P. 129347 - 129347

Published: June 11, 2022

Language: Английский

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Recent advances on emerging biosensing technologies and on-site analytical devices for detection of drug-resistant foodborne pathogens

TrAC Trends in Analytical Chemistry, Journal Year: 2023, Volume and Issue: 167, P. 117258 - 117258

Published: Aug. 26, 2023

Language: Английский

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Lipid-based nanoparticles as drug delivery carriers for cancer therapy

Frontiers in Oncology, Journal Year: 2024, Volume and Issue: 14

Published: April 10, 2024

Cancer is a severe disease that results in death all countries of the world. A nano-based drug delivery approach best alternative, directly targeting cancer tumor cells with improved cellular uptake. Different types nanoparticle-based carriers are advanced for treatment cancer, and to increase therapeutic effectiveness safety therapy, many substances have been looked into as carriers. Lipid-based nanoparticles (LBNPs) significantly attracted interest recently. These natural biomolecules alternate other polymers frequently recycled medicine due their amphipathic properties. Lipid typically provide variety benefits, including biocompatibility biodegradability. This review covers different classes LBNPs, characterization synthesis technologies. discusses most significant advancements lipid nanoparticle technology use administration. Moreover, also emphasized applications used types.

Language: Английский

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Recent developments in Raman spectral analysis of microbial single cells: Techniques and applications

Critical Reviews in Food Science and Nutrition, Journal Year: 2021, Volume and Issue: 62(16), P. 4294 - 4308

Published: July 12, 2021

The conventional microbial cell analyses are mostly population-averaged methods that conceal the characteristics of single-cell in community. Single-cell analysis can provide information on functional and structural variation each cell, resulting elimination long tedious cultivation techniques. Raman spectroscopy is a label-free, noninvasive, in-vivo method ideal for measurement to obtain spatially resolved chemical information. In current review, recent developments spectroscopic techniques characterization at level presented, focusing imaging single cells study intracellular distribution different components. review also discusses limitation challenges technique put forward some future outlook improving spectroscopy-based analysis. have potential precision measurements, metabolic analysis, antibiotic susceptibility testing, resuscitation capability, correlating phenotypic genomics cells, integration with other such as microfluidics, stable isotope probing (SIP), atomic force microscope further improve resolution extensive Future focuses should be given advance algorithms data standardized reference libraries, automated isolation future.

Language: Английский

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Recent advances in surface enhanced Raman spectroscopy for bacterial pathogen identifications

Journal of Advanced Research, Journal Year: 2022, Volume and Issue: 51, P. 91 - 107

Published: Dec. 19, 2022

The rapid and reliable detection of pathogenic bacteria at an early stage is a highly significant research field for public health. However, most traditional approaches pathogen identification are time-consuming labour-intensive, which may cause physicians making inappropriate treatment decisions based on incomplete diagnosis patients with unknown infections, leading to increased morbidity mortality. Therefore, novel methods constantly required face the emerging challenges bacterial identification. In particular, Raman spectroscopy (RS) becoming attractive method accurate pathogens in recent years, among newly developed surface-enhanced (SERS) shows promising potential.Recent advances infections were discussed focuses development SERS its applications complex clinical settings.The current review describes classification using surface enhanced developing more diagnosis. initial part this gives brief overview mechanism technology approach detect samples. label-based label-free strategies several SERS-compatible technologies applications, as well analytical procedures examples chemometric SERS, introduced. computational pre-processing spectra highlights limitations perspectives technique also discussed.Taken together, systematic provides overall summary application potential direct samples such blood, urine sputum, etc.

Language: Английский

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An efficient SERS platform for the ultrasensitive detection of Staphylococcus aureus and Listeria monocytogenes via wheat germ agglutinin-modified magnetic SERS substrate and streptavidin/aptamer co-functionalized SERS tags

Analytica Chimica Acta, Journal Year: 2021, Volume and Issue: 1187, P. 339155 - 339155

Published: Oct. 8, 2021

Language: Английский

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Electrogenic Bacteria Promise New Opportunities for Powering, Sensing, and Synthesizing

Small, Journal Year: 2022, Volume and Issue: 18(18)

Published: Feb. 4, 2022

Abstract Considerable research efforts into the promises of electrogenic bacteria and commercial opportunities they present are attempting to identify potential feasible applications. Metabolic electrons from enable electricity generation sufficient power portable or small‐scale applications, while quantifiable electric signal in a miniaturized device platform can be sensitive enough monitor respond changes environmental conditions. Nanomaterials produced by offer an innovative bottom‐up biosynthetic approach synergize bacterial electron transfer create effective coupling at cell–electrode interface. Furthermore, revolutionize field bioelectronics effectively interfacing electronics with microbes through extracellular transfer. Here, these new directions for their recent integration micro‐ nanosystems comprehensively discussed specific attention toward distinct applications powering, sensing, synthesizing. challenges individual strategies solutions provided valuable guidelines practical implementation. Finally, perspective view on how use hold immeasurable promise development future presented.

Language: Английский

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SERS-based antibiotic susceptibility testing: Towards point-of-care clinical diagnosis

Biosensors and Bioelectronics, Journal Year: 2022, Volume and Issue: 219, P. 114843 - 114843

Published: Oct. 25, 2022

Language: Английский

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Single-cell pathogen diagnostics for combating antibiotic resistance

Nature Reviews Methods Primers, Journal Year: 2023, Volume and Issue: 3(1)

Published: Feb. 2, 2023

Language: Английский

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