ACS Sensors,
Journal Year:
2024,
Volume and Issue:
9(5), P. 2421 - 2428
Published: April 22, 2024
A
core-shell
nanostructure
of
gold
nanoparticles@covalent
organic
framework
(COF)
loaded
with
palladium
nanoparticles
(AuNPs@COF-PdNPs)
was
designed
for
the
rapid
monitoring
catalytic
reactions
surface-enhanced
Raman
spectroscopy
(SERS).
The
prepared
by
coating
COF
layer
on
AuNPs
and
then
in
situ
synthesizing
PdNPs
within
shell.
With
respective
SERS
activity
performance
AuNP
core
COF-PdNPs
shell,
can
be
directly
used
study
reaction
processes.
It
shown
that
confinement
effect
resulted
high
dispersity
outstanding
AuNPs@COF-PdNPs,
thus
improving
rate
constant
AuNPs@COF-PdNPs-catalyzed
hydrogenation
reduction
10
times
higher
than
obtained
Au/Pd
NPs.
In
addition,
serve
as
a
protective
shell
to
make
AuNPs@COF-PdNPs
possess
excellent
reusability.
Moreover,
loading
found
favor
avoiding
intermediate
products
achieve
total
conversion
rate.
also
showed
great
activities
toward
Suzuki-Miyaura
coupling
reaction.
Taken
together,
proposed
has
potential
exploring
processes
interfacial
reactions.
ACS Nano,
Journal Year:
2024,
Volume and Issue:
18(22), P. 14000 - 14019
Published: May 20, 2024
While
surface-enhanced
Raman
spectroscopy
(SERS)
has
experienced
substantial
advancements
since
its
discovery
in
the
1970s,
it
is
an
opportunity
to
celebrate
achievements,
consider
ongoing
endeavors,
and
anticipate
future
trajectory
of
SERS.
In
this
perspective,
we
encapsulate
latest
breakthroughs
comprehending
electromagnetic
enhancement
mechanisms
SERS,
revisit
CT
semiconductors.
We
then
summarize
strategies
improve
sensitivity,
selectivity,
reliability.
After
addressing
experimental
advancements,
comprehensively
survey
progress
on
spectrum–structure
correlation
SERS
showcasing
their
important
role
promoting
development.
Finally,
forthcoming
directions
opportunities,
especially
deepening
our
insights
into
chemical
or
biological
processes
establishing
a
clear
correlation.
Journal of Pharmaceutical Analysis,
Journal Year:
2024,
Volume and Issue:
14(11), P. 100959 - 100959
Published: Feb. 28, 2024
An
optical
biosensor
is
a
specialized
analytical
device
that
utilizes
the
principles
of
optics
and
light
in
bimolecular
processes.
Localized
surface
plasmon
resonance
(LSPR)
phenomenon
realm
nanophotonics
occurs
when
metallic
nanoparticles
(NPs)
or
nanostructures
interact
with
incident
light.
Conversely,
surface-enhanced
Raman
spectroscopy
(SERS)
an
influential
technique
based
on
scattering,
wherein
it
amplifies
signals
molecules
they
are
situated
near
specific
specially
designed
nanostructures.
A
detailed
exploration
recent
ground-breaking
developments
biosensors
employing
LSPR
SERS
technologies
has
been
thoroughly
discussed
along
their
underlying
working
mechanisms.
chip
created,
featuring
high-density
deposition
gold
(AuNPs)
under
varying
ligand
concentration
reaction
duration
substrate.
ordinary
description,
visual
illustration,
provided
for
concepts
such
as
sensogram,
refractive
index
shift,
(SPR),
evanescent
field,
Rayleigh
well
electromagnetic
enhancement
chemical
enhancement.
both
have
advantages
disadvantages,
but
widely
used
some
over
LSPR,
like
specificity,
high
sensitivity,
multiplexing,
versatility
different
fields.
This
review
confirms
elucidates
significance
disease
biomarker
identification.
play
vital
role
detection
various
types
cancer,
cervical
ovarian
endometrial
prostate
colorectal
brain
tumors.
proposed
offers
potential
applications
early
diagnosis
monitoring
viral
disease,
bacterial
infectious
diseases,
fungal
diabetes,
cardiac
biosensing.
provide
new
direction
environmental
monitoring,
food
safety,
refining
impurities
from
water
samples,
lead
detection.
The
understanding
these
still
limited
challenging.
ACS Omega,
Journal Year:
2024,
Volume and Issue:
9(4), P. 4819 - 4830
Published: Jan. 18, 2024
One
of
the
requirements
an
efficient
surface-enhanced
Raman
spectroscopy
(SERS)
substrate
is
a
developed
surface
morphology
with
high
density
"hot
spots",
nm-scale
spacings
between
plasmonic
nanoparticles.
Of
particular
interest
are
architectures
that
could
enable
self-localization
(enrichment)
analyte
in
hot
spots.
We
report
straightforward
method
fabrication
SERS
substrates
comply
these
requirements.
The
basis
large-area
film
tightly
packed
SiO2
spheres
formed
by
their
quick
self-assembling
upon
drop
casting
from
solution.
Thermally
evaporated
thin
Ag
layer
converted
thermal
annealing
into
nanoparticles
(NPs)
self-assembled
trenches
silica
spheres,
i.e.,
places
where
molecules
get
localized
deposition
solution
and
drying.
Therefore,
obtained
enables
enrichment
spots
densely
arranged
NPs.
efficiency
demonstrated
detection
Rhodamine
6G
down
to
10–13
mol/L
enhancement
factor
∼108,
as
well
low
concentrations
various
nonresonant
analytes,
both
small
dye
large
biomolecules.
approach
very
for
implementation
can
be
further
extended
using
gold
or
other
ACS Nano,
Journal Year:
2024,
Volume and Issue:
18(32), P. 20835 - 20850
Published: Aug. 1, 2024
Surface-enhanced
Raman
scattering
(SERS)
provides
detailed
information
about
the
binding
of
molecules
at
interfaces
and
their
interactions
with
local
environment
due
to
large
enhancement
scattering.
This
arises
from
a
combination
electromagnetic
mechanism
(EM)
chemical
(CM).
While
it
is
commonly
accepted
that
EM
gives
rise
most
enhancement,
spectral
changes
originate
CM.
To
elucidate
rich
contained
in
SERS
spectra
interfaces,
comprehensive
understanding
mechanisms
necessary.
In
this
Perspective,
we
discuss
current
highlight
interplay
complex
environments.
We
will
also
emerging
areas
where
development
computational
theoretical
models
needed
specific
attention
given
how
CM
contributes
changes.
Future
efforts
modeling
should
focus
on
overcoming
challenges
presented
review
order
capture
complexity
SERS.
ACS Sensors,
Journal Year:
2024,
Volume and Issue:
9(5), P. 2567 - 2574
Published: May 2, 2024
In
vivo
drug
monitoring
is
crucial
for
evaluating
the
effectiveness
and
safety
of
treatment.
Blood
sampling
analysis
current
gold
standard
but
needs
professional
skills
cannot
meet
requirements
point-of-care
testing.
Dermal
interstitial
fluid
(ISF)
showed
great
potential
to
replace
blood
in
monitoring;
however,
detection
was
challenging,
distribution
behavior
ISF
still
unclear
until
now.
this
study,
we
proposed
surface-enhanced
Raman
spectroscopy
(SERS)
microneedles
(MNs)
painless
real-time
drugs
after
intravenous
injection.
Using
methylene
blue
(MB)
mitoxantrone
(MTO)
as
model
drugs,
innovative
core–satellite
structured
Au@Ag
SERS
substrate,
hydrogel
coating
over
MNs,
rendered
sensitive
quantitative
mice
within
10
min.
Based
on
technique,
pharmacokinetics
two
investigated
compared
with
those
blood,
where
were
analyzed
via
liquid
chromatography–mass
spectrometry.
It
found
that
MB
concentration
comparable,
whereas
MTO
2–3
orders
magnitude
lower
than
blood.
This
work
an
efficient
tool
monitoring.
More
importantly,
it
experimentally
proved
penetration
ratio
drug-dependent,
providing
insightful
information
into
a
alternative
detection.
Nanoscale Horizons,
Journal Year:
2024,
Volume and Issue:
9(12), P. 2085 - 2166
Published: Jan. 1, 2024
This
comprehensive
review
summarizes
the
past,
present,
and
future
of
plasmonic
NP-based
sensors
in
terms
different
sensing
platforms,
chemical
biological
analytes,
expected
technologies.
Chemical Society Reviews,
Journal Year:
2024,
Volume and Issue:
53(10), P. 5118 - 5148
Published: Jan. 1, 2024
3D
cancer
models
recapitulate
the
tumor
microenvironment
and
serve
as
a
platform
to
study
cell
behavior,
drug
discovery
early
diagnosis,
which
can
be
monitored
chemically
with
subcellular
resolution
in
real
time,
via
SERS.
