Identification and Prioritization of Environmental Organic Pollutants: From an Analytical and Toxicological Perspective

Chemical Reviews, Journal Year: 2023, Volume and Issue: 123(17), P. 10584 - 10640

Published: Aug. 2, 2023

Exposure to environmental organic pollutants has triggered significant ecological impacts and adverse health outcomes, which have been received substantial increasing attention. The contribution of unidentified chemical components is considered as the most knowledge gap in understanding combined effects pollutant mixtures. To address this issue, remarkable analytical breakthroughs recently made. In review, basic principles on recognition are overviewed. Complementary methodologies (i.e., quantitative structure–activity relationship prediction, mass spectrometric nontarget screening, effect-directed analysis) experimental platforms briefly described. stages technique development and/or essential parts workflow for each then reviewed. Finally, plausible paths applications future screening methods, interdisciplinary techniques achieving toxicant identification, burgeoning strategies risk assessment cocktails discussed.

Language: Английский

---

Uptake, Metabolism, and Accumulation of Tire Wear Particle-Derived Compounds in Lettuce

Environmental Science & Technology, Journal Year: 2022, Volume and Issue: 57(1), P. 168 - 178

Published: Dec. 28, 2022

Tire wear particle (TWP)-derived compounds may be of high concern to consumers when released in the root zone edible plants. We exposed lettuce plants TWP-derived diphenylguanidine (DPG), hexamethoxymethylmelamine (HMMM), benzothiazole (BTZ), N-phenyl-N′-(1,3-dimethylbutyl)-p-phenylenediamine (6PPD), and its quinone transformation product (6PPD-q) at concentrations 1 mg L–1 hydroponic solutions over 14 days analyze if they are taken up metabolized by Assuming that TWP a long-term source plants, we further investigated effect leaching from on concentration leachate leaves adding constantly solutions. Concentrations leaves, roots, nutrient solution were quantified triple quadrupole mass spectrometry, metabolites identified Orbitrap resolution spectrometry. This study demonstrates readily with measured maximum leaf between ∼0.75 (6PPD) 20 μg g–1 (HMMM). Although these plant, several products, most which proved more stable than parent compounds. Furthermore, continuous led resupply replenishment leaves. The stability largely unknown toxicities is particularly concerning an important new aspect for impact assessment environment.

Language: Английский

---

Suspect and Nontarget Screening Reveal the Underestimated Risks of Antibiotic Transformation Products in Wastewater Treatment Plant Effluents

Environmental Science & Technology, Journal Year: 2023, Volume and Issue: 57(45), P. 17439 - 17451

Published: Nov. 6, 2023

Antibiotics are anthropogenic contaminants with a global presence and of deep concern in aquatic environments, while less is known about the occurrence risks their transformation products (TPs). Herein, we developed comprehensive suspect nontarget screening workflow based on high-resolution mass spectrometry to identify unknown antibiotic TPs wastewater treatment plant effluents. We identified 211 compounds (35 parent antibiotics 176 TPs) at confidence levels ≥3 107 originated from macrolides. were quantified by 17 standards semiquantified predicted response factors accounted for 55.6-95.1% (76.7% average) total concentrations parents TPs. 22.2%, 63.1%, 18.8% estimated be more persistent, mobile, toxic than antibiotics, respectively. Further ecological risk assessment toxicity organisms revealed that cumulative generally higher those parents. Despite newly formed N-oxide TPs, tertiary process (mainly ozonation) could decrease averaged 20.3% 36.2% antibiotic-related compounds. This study highlights necessity include environmental scrutiny different environments.

Language: Английский

---

Understanding the biodegradation pathways of azo dyes by immobilized white-rot fungus, Trametes hirsuta D7, using UPLC-PDA-FTICR MS supported by in silico simulations and toxicity assessment

Chemosphere, Journal Year: 2022, Volume and Issue: 313, P. 137505 - 137505

Published: Dec. 8, 2022

Language: Английский

---

Revealing specific transformation pattern of sulfonamides during wastewater biological treatment processes by molecular networking nontarget screening

Water Research, Journal Year: 2023, Volume and Issue: 235, P. 119895 - 119895

Published: March 20, 2023

Language: Английский

---

Deciphering the role of extracellular polymeric substances in the adsorption and biotransformation of organic micropollutants during anaerobic wastewater treatment

Water Research, Journal Year: 2024, Volume and Issue: 257, P. 121718 - 121718

Published: May 3, 2024

Language: Английский

---

Quantitative identification of the co-exposure effects of e-waste pollutants on human oxidative stress by explainable machine learning

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 466, P. 133560 - 133560

Published: Jan. 19, 2024

Language: Английский

---

Transformation mechanisms of antidepressants in biological wastewater treatment: Removal kinetic, transformation products and pathways

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 493, P. 152557 - 152557

Published: May 25, 2024

Language: Английский

---

Microbes as Resources to Remove PPCPs and Improve Water Quality

Microbial Biotechnology, Journal Year: 2025, Volume and Issue: 18(1)

Published: Jan. 1, 2025

ABSTRACT The inadequate removal of pharmaceuticals and personal care products (PPCPs) by traditional wastewater treatment plants (WWTPs) poses a significant environmental public health challenge. Residual PPCPs find their way into aquatic ecosystems, leading to bioaccumulation in biota, the dissemination antibiotic resistance genes (ARGs), contamination both water sources vegetables. These persistent pollutants can have negative effects on human health, ranging from development endocrine disruption. To mitigate these risks, there is growing interest exploiting microorganisms enzymes for bioremediation purposes. By harnessing metabolic capabilities microbial communities, be efficiently degraded, transformed, or sequestered systems. Additionally, communities exhibit remarkable adaptability resilience diverse PPCP contaminants, further underscoring potential as sustainable cost‐effective solutions treatment. This review explores promise an approach addressing complex challenges posed contamination, emphasising its safeguard integrity well‐being.

Language: Английский

---

Microbial Metabolic Enzymes, Pathways and Microbial Hosts for Co-Metabolic Degradation of Organic Micropollutants in Wastewater

Water Research, Journal Year: 2025, Volume and Issue: unknown, P. 123229 - 123229

Published: Jan. 1, 2025

Language: Английский

---