Vegetarian Diet: An Overview through the Perspective of Quality of Life Domains

International Journal of Environmental Research and Public Health, Journal Year: 2021, Volume and Issue: 18(8), P. 4067 - 4067

Published: April 12, 2021

Vegetarianism has gained more visibility in recent years. Despite the well-described effects of a vegetarian diet on health, its influence quality life individuals who follow it still needs to be properly investigated. Quality relates subjective perception well-being and functionality, encompasses four main domains: physical, psychological, social, environmental. The adoption diet, despite being dietary pattern, could potentially influenced by all these domains, either positively or negatively. This review aims present an overview background, conceptualization, features, potential vegetarianism domains. choice adopting have positive outcomes, such as better physical feelings related morally correct attitude, increased sense belonging (to community), lower environmental impact. Other factors, however, negative impact those choosing abstain from meats other animal products, especially when they go beyond one’s control. These include environment, social/cultural group which person is inserted, gender-based differences, economic aspects, limited access wide variety plant-based foods. It important understand diet—beyond nutritional aspects. Not only do studies this area provide consistent data, but may also contribute mitigating factors that might prevent already it.

Language: Английский

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Intermittent fasting in the prevention and treatment of cancer

CA A Cancer Journal for Clinicians, Journal Year: 2021, Volume and Issue: 71(6), P. 527 - 546

Published: Aug. 12, 2021

Abstract Chronic caloric restriction (CR) has powerful anticarcinogenic actions in both preclinical and clinical studies but may be difficult to sustain. As an alternative CR, there been growing interest intermittent fasting (IF) the scientific lay community as a result of promising study results, mainly experimental animal models. According survey by International Food Information Council Foundation, IF become most popular diet last year, patients with cancer are seeking advice from oncologists about its beneficial effects for prevention treatment. However, discussed this review, results rodents controversial suggest potential detrimental certain oncologic conditions. The on human incidence prognosis remain unknown because lack high‐quality randomized trials. Preliminary that prolonged some who have is safe potentially capable decreasing chemotherapy‐related toxicity tumor growth. additional trials needed elucidate risks benefits cancer, authors would not currently recommend undergoing active treatment partake outside context trial. considered adults cancer‐prevention through means weight management, whether itself affects cancer‐related metabolic molecular pathways remains unanswered.

Language: Английский

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Microbiota-Centered Interventions: The Next Breakthrough in Immuno-Oncology?

Cancer Discovery, Journal Year: 2021, Volume and Issue: 11(10), P. 2396 - 2412

Published: Aug. 16, 2021

The cancer-immune dialogue subject to immuno-oncological intervention is profoundly influenced by microenvironmental factors. Indeed, the mucosal microbiota-and more specifically, intestinal ecosystem-influences tone of anticancer immune responses and clinical benefit immunotherapy. Antibiotics blunt efficacy checkpoint inhibitors (ICI), fecal microbial transplantation may restore responsiveness ICI-resistant melanoma. Here, we review yin yang bacteria at crossroads between barrier, metabolism, local or systemic during therapies. We discuss diagnostic tools identify gut dysbiosis future prospects microbiota-based therapeutic interventions. SIGNIFICANCE: Given recent proof concept potential in patients with melanoma primarily resistant PD-1 blockade, it timely how why antibiotics compromise cancer immunotherapy, describe balance beneficial harmful species play therapies, introduce for microbiota-centered interventions immuno-oncology.

Language: Английский

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Cruciferous Vegetables and Their Bioactive Metabolites: from Prevention to Novel Therapies of Colorectal Cancer

Evidence-based Complementary and Alternative Medicine, Journal Year: 2022, Volume and Issue: 2022, P. 1 - 20

Published: April 11, 2022

The Brassicaceae family, known as cruciferous vegetables, includes many economically important species, mainly edible oil plants, vegetable spice and feed plants. Cruciferous vegetables are foods rich in nutritive composition also a good source of dietary fiber. Besides, contain various bioactive chemicals glucosinolates S-methyl cysteine sulfoxide, including sulphur-containing cancer-protective chemicals. Numerous studies have reported that daily intake sulphurous helps prevent cancer formation reduces incidence, especially colorectal cancer, through mechanisms. potential mechanisms these compounds preventing experimental follows: protecting cells against DNA damage, inactivating carcinogenic substances, showing antiviral antibacterial effects, triggering apoptosis with disrupted structure, inhibiting tumour cell migration causing metastasis the development tumour-feeding vessels (angiogenesis). These beneficial anticancer effects generally associated their some secondary metabolites, well other phenolic compounds, seed oils, fiber literature. This review aims to examine roles metabolites prevention treatment cancer.

Language: Английский

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Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis

Cell stem cell, Journal Year: 2021, Volume and Issue: 28(11), P. 1922 - 1935.e5

Published: Sept. 15, 2021

Language: Английский

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