Advanced Science,
Journal Year:
2024,
Volume and Issue:
11(20)
Published: March 19, 2024
Abstract
Layered
double
hydroxides
(LDHs)
have
been
widely
studied
for
biomedical
applications
due
to
their
excellent
properties,
such
as
good
biocompatibility,
degradability,
interlayer
ion
exchangeability,
high
loading
capacity,
pH‐responsive
release,
and
large
specific
surface
area.
Furthermore,
the
flexibility
in
structural
composition
ease
of
modification
LDHs
makes
it
possible
develop
specifically
functionalized
meet
needs
different
applications.
In
this
review,
recent
advances
applications,
which
include
LDH‐based
drug
delivery
systems,
cancer
diagnosis
therapy,
tissue
engineering,
coatings,
functional
membranes,
biosensors,
are
comprehensively
discussed.
From
these
various
research
fields,
can
be
seen
that
there
is
great
potential
possibility
use
However,
at
same
time,
must
recognized
actual
clinical
translation
still
very
limited.
Therefore,
current
limitations
related
on
discussed
by
combining
limited
examples
with
requirements
biomaterials.
Finally,
an
outlook
future
provided.
Molecules,
Journal Year:
2021,
Volume and Issue:
26(19), P. 5905 - 5905
Published: Sept. 29, 2021
The
drug
delivery
system
enables
the
release
of
active
pharmaceutical
ingredient
to
achieve
a
desired
therapeutic
response.
Conventional
systems
(tablets,
capsules,
syrups,
ointments,
etc.)
suffer
from
poor
bioavailability
and
fluctuations
in
plasma
level
are
unable
sustained
release.
Without
an
efficient
mechanism,
whole
process
can
be
rendered
useless.
Moreover,
has
delivered
at
specified
controlled
rate
target
site
as
precisely
possible
maximum
efficacy
safety.
Controlled
developed
combat
problems
associated
with
conventional
delivery.
There
been
tremendous
evolution
past
two
decades
ranging
macro
scale
nano
intelligent
targeted
initial
part
this
review
provides
basic
understanding
emphasis
on
pharmacokinetics
drug.
It
also
discusses
their
limitations.
Further,
discussed
detail
design
considerations,
classifications
drawings.
In
addition,
nano-drug
delivery,
smart
using
stimuli-responsive
biomaterials
is
recent
key
findings.
paper
concludes
challenges
faced
future
directions
npj Flexible Electronics,
Journal Year:
2021,
Volume and Issue:
5(1)
Published: April 12, 2021
Wearable
devices
have
found
numerous
applications
in
healthcare
ranging
from
physiological
diseases,
such
as
cardiovascular
hypertension
and
muscle
disorders
to
neurocognitive
disorders,
Parkinson’s
disease,
Alzheimer’s
disease
other
psychological
diseases.
Different
types
of
wearables
are
used
for
this
purpose,
example,
skin-based
including
tattoo-based
wearables,
textile-based
biofluidic-based
wearables.
Recently,
also
shown
encouraging
improvements
a
drug
delivery
system;
therefore,
enhancing
its
utility
towards
personalized
healthcare.
These
contain
inherent
challenges,
which
need
be
addressed
before
their
commercialization
fully
system.
This
paper
reviews
different
wearable
currently
being
the
field.
It
highlights
efficacy
monitoring
diseases
(HWDs)
diagnostic
treatment
purposes.
Additionally,
current
challenges
limitations
these
field
along
with
future
perspectives
reviewed.
Signal Transduction and Targeted Therapy,
Journal Year:
2023,
Volume and Issue:
8(1)
Published: Nov. 3, 2023
Abstract
Smart
nanoparticles,
which
can
respond
to
biological
cues
or
be
guided
by
them,
are
emerging
as
a
promising
drug
delivery
platform
for
precise
cancer
treatment.
The
field
of
oncology,
nanotechnology,
and
biomedicine
has
witnessed
rapid
progress,
leading
innovative
developments
in
smart
nanoparticles
safer
more
effective
therapy.
In
this
review,
we
will
highlight
recent
advancements
including
polymeric
dendrimers,
micelles,
liposomes,
protein
cell
membrane
mesoporous
silica
gold
iron
oxide
quantum
dots,
carbon
nanotubes,
black
phosphorus,
MOF
others.
We
focus
on
their
classification,
structures,
synthesis,
intelligent
features.
These
possess
the
ability
various
external
internal
stimuli,
such
enzymes,
pH,
temperature,
optics,
magnetism,
making
them
systems.
Additionally,
review
explore
latest
studies
tumor
targeting
functionalizing
surfaces
with
tumor-specific
ligands
like
antibodies,
peptides,
transferrin,
folic
acid.
also
summarize
different
types
options,
small
molecules,
proteins,
nucleic
acids,
even
living
cells,
potential
use
While
is
promising,
acknowledge
challenges
clinical
prospects
associated
use.
Finally,
propose
blueprint
that
involves
artificial
intelligence-powered
treatment
applications.
By
harnessing
aims
usher
new
era
personalized
therapy,
providing
patients
individualized
options.
Nanomaterials,
Journal Year:
2020,
Volume and Issue:
10(4), P. 656 - 656
Published: April 1, 2020
Nanomedicine
is
a
field
of
science
that
uses
nanoscale
materials
for
the
diagnosis
and
treatment
human
disease.
It
has
emerged
as
an
important
aspect
therapeutics,
but
at
same
time,
also
raises
concerns
regarding
safety
nanomaterials
involved.
Recent
applications
functionalized
biodegradable
have
significantly
improved
profile
nanomedicine.
Cancer Cell International,
Journal Year:
2021,
Volume and Issue:
21(1)
Published: June 24, 2021
Abstract
The
study
describes
the
current
state
of
knowledge
on
nanotechnology
and
its
utilization
in
medicine.
focus
this
manuscript
was
properties,
usage
safety,
potentially
valuable
applications
chitosan-based
nanomaterials.
Chitosan
nanoparticles
have
high
importance
nanomedicine,
biomedical
engineering,
discovery
development
new
drugs.
reviewed
studies
regarding
use
for
creating
release
systems
with
improved
bioavailability,
increased
specificity
sensitivity,
reduced
pharmacological
toxicity
Nowadays,
effective
cancer
treatment
is
a
global
problem,
recent
advances
nanomedicine
are
great
importance.
Special
attention
put
application
chitosan
developing
system
anticancer
drug
delivery.
Pre-clinical
clinical
support
nanomedicine.
This
overviews
last
progresses
utilization,
stability,
bioavailability
nanoencapsulation
their
safety.
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2020,
Volume and Issue:
8
Published: Feb. 11, 2020
Polymeric
biomaterials
have
found
widespread
applications
in
nanomedicine,
and
PLGA
particular
has
been
successfully
implemented
numerous
drug
delivery
formulations
due
to
its
synthetic
malleability
biocompatibility.
However,
the
need
for
preconception
these
is
increasing,
this
can
be
achieved
by
selection
elimination
of
design
variables
order
systems
tailored
their
specific
applications.
The
starting
materials
preparation
methods
shown
influence
various
parameters
PLGA-based
nanocarriers
implementation
systems,
while
computational
simulations
as
a
component
formulation
studies
provide
valuable
information
on
characteristics.
This
review
provides
critical
summary
synthesis
bio-medicine
outlines
experimental
considerations
systems.
Environmental Chemistry Letters,
Journal Year:
2020,
Volume and Issue:
19(1), P. 583 - 611
Published: Sept. 16, 2020
Abstract
The
inert
nature
of
most
commercial
polymers
and
nanomaterials
results
in
limitations
applications
various
industrial
fields.
This
can
be
solved
by
surface
modifications
to
improve
physicochemical
biological
properties,
such
as
adhesion,
printability,
wetting
biocompatibility.
Polymer
functionalization
allows
graft
specific
moieties
conjugate
molecules
that
material
performances.
In
the
last
decades,
several
approaches
have
been
designed
industry
academia
functional
groups
on
surfaces.
Here,
we
review
decoration
nanomaterials,
with
focus
major
medical
field,
textile
industry,
water
treatment
food
packaging.
We
discuss
advantages
challenges
polymer
functionalization.
More
knowledge
is
needed
biology
behind
cell–polymer
interactions,
nanosafety
manufacturing
at
scale.
ACS Applied Nano Materials,
Journal Year:
2021,
Volume and Issue:
4(7), P. 6471 - 6496
Published: July 2, 2021
Nanoparticle
size
plays
a
central
role
in
determining
material
properties
and
performance
biomedical
applications.
A
wide
variety
of
functional
nanomaterials
nano-bioconjugates
have
been
developed
for
monitoring
biochemical
activity,
controlling
biological
functions,
therapeutic
This
review
focuses
on
the
nanoparticle
(typically
range
1–100
nm)
various
applications,
origin
such
effect,
optimum
requirement
best
different
First,
we
discuss
nanoscale
units
present
life
processes
along
with
their
role.
Next,
size-dependent
some
well-known
nanoparticles
how
those
are
exploited
that
used
Then,
highlight
designed
specific
Finally,
attempt
to
correlate
evolutionary
selection
toward
functions.
