An Overview of the Factors Involved in Biofilm Production by the Enterococcus Genus DOI Open Access
Pavel Șchiopu, Dan Alexandru Țoc,

Ioana Alina Colosi

et al.

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(14), P. 11577 - 11577

Published: July 18, 2023

Enterococcus species are known for their ability to form biofilms, which contributes survival in extreme environments and involvement persistent bacterial infections, especially the case of multi-drug-resistant strains. This review aims provide a comprehensive understanding mechanisms underlying biofilm formation clinically important such as faecalis less studied but increasingly faecium, explores potential strategies eradication. Biofilm involves complex interplay genes virulence factors, including gelatinase, cytolysin, Secreted antigen A, pili, microbial surface components that recognize adhesive matrix molecules (MSCRAMMs), DNA release. Quorum sensing, process intercellular communication, mediated by peptide pheromones Cob, Ccf, Cpd, plays crucial role coordinating development targeting gene expression regulation. Additionally, regulation extracellular (eDNA) release has emerged fundamental component formation. In E. faecalis, autolysin N-acetylglucosaminidase proteases gelatinase serin protease key players this process, influencing virulence. Targeting eDNA may offer promising avenue intervention biofilm-producing infections. Overall, gaining insights into intricate directions anti-biofilm therapeutic research, with purpose reducing burden Enterococcus-associated

Language: Английский

Pseudomonas aeruginosa Biofilms DOI Open Access
Minh Tam Tran Thi, David Wibowo, Bernd H. A. Rehm

et al.

International Journal of Molecular Sciences, Journal Year: 2020, Volume and Issue: 21(22), P. 8671 - 8671

Published: Nov. 17, 2020

Pseudomonas aeruginosa is an opportunistic human pathogen causing devastating acute and chronic infections in individuals with compromised immune systems. Its highly notorious persistence clinical settings attributed to its ability form antibiotic-resistant biofilms. Biofilm architecture built mostly by autogenic extracellular polymeric substances which function as a scaffold encase the bacteria together on surfaces, protect them from environmental stresses, impedes phagocytosis thereby conferring capacity for colonization long-term persistence. Here we review current knowledge P. biofilms, development stages, molecular mechanisms of invasion conferred Explosive cell lysis within bacterial biofilm produce essential communal materials, interspecies biofilms commensal Streptococcus virulence possibly improves disease conditions will also be discussed. Recent research diagnostics investigated. Finally, therapeutic strategies treatment along their advantages limitations compiled.

Language: Английский

Citations

622

The microbiome-shaping roles of bacteriocins DOI
Simon Heilbronner, Bernhard Krismer, Heike Brötz‐Oesterhelt

et al.

Nature Reviews Microbiology, Journal Year: 2021, Volume and Issue: 19(11), P. 726 - 739

Published: June 1, 2021

Language: Английский

Citations

283

Mechanomicrobiology: how bacteria sense and respond to forces DOI
Yves F. Dufrêne, Alexandre Persat

Nature Reviews Microbiology, Journal Year: 2020, Volume and Issue: 18(4), P. 227 - 240

Published: Jan. 20, 2020

Language: Английский

Citations

248

Plant Growth Stimulation by Microbial Consortia DOI Creative Commons
Gustavo Santoyo, Paulina Guzmán-Guzmán, Fannie Isela Parra-Cota

et al.

Agronomy, Journal Year: 2021, Volume and Issue: 11(2), P. 219 - 219

Published: Jan. 24, 2021

Plant-associated microorganisms play an important role in agricultural production. Although various studies have shown that single can exert beneficial effects on plants, it is increasingly evident when a microbial consortium—two or more interacting microorganisms—is involved, additive synergistic results be expected. This occurs, part, due to the fact multiple species perform variety of tasks ecosystem like rhizosphere. Therefore, mechanisms plant growth stimulation (i.e., enhanced nutrient availability, phytohormone modulation, biocontrol, biotic and abiotic stress tolerance) exerted by different players within rhizosphere, such as plant-growth-promoting bacteria (PGPB) fungi (such Trichoderma Mycorrhizae), are reviewed. In addition, their interaction activity highlighted they act part consortium, mainly mixtures PGPB, PGPB–Mycorrhizae, PGPB–Trichoderma, under normal diverse conditions. Finally, we propose expansion use consortia, well increase research facilitate best most consistent field.

Language: Английский

Citations

231

Gastrointestinal biofilms in health and disease DOI
Jean‐Paul Motta, John L. Wallace, André G. Buret

et al.

Nature Reviews Gastroenterology & Hepatology, Journal Year: 2021, Volume and Issue: 18(5), P. 314 - 334

Published: Jan. 28, 2021

Language: Английский

Citations

205

The ecological roles of bacterial chemotaxis DOI
Johannes M. Keegstra, Francesco Carrara, Roman Stocker

et al.

Nature Reviews Microbiology, Journal Year: 2022, Volume and Issue: 20(8), P. 491 - 504

Published: March 15, 2022

Language: Английский

Citations

191

Infection microenvironment-related antibacterial nanotherapeutic strategies DOI
Zhe Wang, Xingyun Liu, Yanwen Duan

et al.

Biomaterials, Journal Year: 2021, Volume and Issue: 280, P. 121249 - 121249

Published: Nov. 11, 2021

Language: Английский

Citations

182

Quorum sensing for population-level control of bacteria and potential therapeutic applications DOI
Shengbo Wu, Jiaheng Liu, Chunjiang Liu

et al.

Cellular and Molecular Life Sciences, Journal Year: 2019, Volume and Issue: 77(7), P. 1319 - 1343

Published: Oct. 14, 2019

Language: Английский

Citations

157

Environmental fluctuations and their effects on microbial communities, populations and individuals DOI Creative Commons

Jen Nguyen,

Juanita Lara‐Gutiérrez, Roman Stocker

et al.

FEMS Microbiology Reviews, Journal Year: 2020, Volume and Issue: 45(4)

Published: Dec. 5, 2020

From the homeostasis of human health to cycling Earth's elements, microbial activities underlie environmental, medical and industrial processes. These occur in chemical physical landscapes that are highly dynamic experienced by bacteria as fluctuations. In this review, we first discuss how can experience both spatial temporal heterogeneity their environments fluctuations various timescales (seconds seasons) types (nutrient, sunlight, fluid flow, etc.). We then focus primarily on nutrient bacterial communities, populations single cells respond environmental Overall, find ubiquitous diverse, strongly shape behavior, ecology evolution when compared with which conditions remain constant over time. hope review may serve a guide toward understanding significance life, such contributions implications be better assessed exploited.

Language: Английский

Citations

153

Engineered Living Hydrogels DOI
Xinyue Liu, María Eugenia Inda, Yong Lai

et al.

Advanced Materials, Journal Year: 2022, Volume and Issue: 34(26)

Published: March 4, 2022

Living biological systems, ranging from single cells to whole organisms, can sense, process information, and actuate in response changing environmental conditions. Inspired by living engineered nonliving matrices are brought together, which gives rise the technology of materials. By designing functionalities structures matrices, materials be created detect variability surrounding environment adjust their functions accordingly, thereby enabling applications health monitoring, disease treatment, remediation. Hydrogels, a class soft, wet, biocompatible materials, have been widely used as for cells, leading nascent field hydrogels. Here, interactions between hydrogel described, focusing on how hydrogels influence cell behaviors affect properties. The environments, these enable versatile applications, also discussed. Finally, current challenges facing clinical settings highlighted.

Language: Английский

Citations

144