A Framework to Evaluate Devices That Assess Physical Behavior DOI
Sarah Kozey Keadle, Kate Lyden, Scott J. Strath

et al.

Exercise and Sport Sciences Reviews, Journal Year: 2019, Volume and Issue: 47(4), P. 206 - 214

Published: July 8, 2019

Body-worn devices that estimate physical behavior have tremendous potential to address key research gaps. However, there is no consensus on how and processing methods should be developed evaluated, resulting in large differences summary estimates confusion for end users. We propose a phase-based framework developing evaluating emphasizes robust validation studies naturalistic conditions.

Language: Английский

GGIR: A Research Community–Driven Open Source R Package for Generating Physical Activity and Sleep Outcomes From Multi-Day Raw Accelerometer Data DOI Open Access
Jairo H. Migueles, Alex V. Rowlands, Florian Huber

et al.

Journal for the Measurement of Physical Behaviour, Journal Year: 2019, Volume and Issue: 2(3), P. 188 - 196

Published: Sept. 1, 2019

Recent technological advances have transformed the research on physical activity initially based questionnaire data to most recent objective from accelerometers. The shift availability of raw accelerations has increased measurement accuracy, transparency, and potential for harmonization. However, it also shifted need considerable processing expertise researcher. Many users do not this expertise. R package GGIR been made available all as a tool convermulti-day high resolution accelerometer wearable movement sensors into meaningful evidence-based outcomes insightful reports study human daily sleep. This paper aims provide one-stop overview package, papers underpinning theory GGIR, how contributes continued growth package. includes range literature-supported methods clean day-by-day, well full recording, weekly, weekend, weekday estimates sleep parameters. In addition, comes with shell function that enables user process set input files produce csv summary single call, ideal less proficient in R. used over 90 peer-reviewed scientific publications date. evolution time widespread use across areas highlights importance open source software development community advancing behavior research.

Language: Английский

Citations

620

Machine learning and artificial intelligence research for patient benefit: 20 critical questions on transparency, replicability, ethics, and effectiveness DOI Creative Commons
Sebastian J. Vollmer, Bilal A. Mateen,

Gergő Bohner

et al.

BMJ, Journal Year: 2020, Volume and Issue: unknown, P. l6927 - l6927

Published: March 20, 2020

Machine learning, artificial intelligence, and other modern statistical methods are providing new opportunities to operationalise previously untapped rapidly growing sources of data for patient benefit. Despite much promising research currently being undertaken, particularly in imaging, the literature as a whole lacks transparency, clear reporting facilitate replicability, exploration potential ethical concerns, demonstrations effectiveness. Among many reasons why these problems exist, one most important (for which we provide preliminary solution here) is current lack best practice guidance specific machine learning intelligence. However, believe that interdisciplinary groups pursuing impact projects involving intelligence health would benefit from explicitly addressing series questions concerning reproducibility, ethics, effectiveness (TREE). The 20 critical proposed here framework inform design, conduct, reporting; editors peer reviewers evaluate contributions literature; patients, clinicians policy makers critically appraise where findings may deliver

Language: Английский

Citations

358

The promise of machine learning in predicting treatment outcomes in psychiatry DOI
Adam M. Chekroud,

Julia Bondar,

Jaime Delgadillo

et al.

World Psychiatry, Journal Year: 2021, Volume and Issue: 20(2), P. 154 - 170

Published: May 18, 2021

For many years, psychiatrists have tried to understand factors involved in response medications or psychotherapies, order personalize their treatment choices. There is now a broad and growing interest the idea that we can develop models decisions using new statistical approaches from field of machine learning applying them larger volumes data. In this pursuit, there has been paradigm shift away experimental studies confirm refute specific hypotheses towards focus on overall explanatory power predictive model when tested new, unseen datasets. paper, review key predict outcomes psychiatry, ranging psychotherapies digital interventions neurobiological treatments. Next, some sources data are being used for development based learning, such as electronic health records, smartphone social media data, potential utility genetics, electrophysiology, neuroimaging cognitive testing. Finally, discuss how far come implementing prediction tools real-world clinical practice. Relatively few retrospective to-date include appropriate external validation procedures, even fewer prospective testing feasibility effectiveness models. Applications psychiatry face same ethical challenges posed by these techniques other areas medicine computer science, which here. short, nascent but important approach improve mental care, several suggest it may be working already.

Language: Английский

Citations

341

GWAS identifies 14 loci for device-measured physical activity and sleep duration DOI Creative Commons
Aiden Doherty, Karl Smith-Byrne, Teresa Ferreira

et al.

Nature Communications, Journal Year: 2018, Volume and Issue: 9(1)

Published: Dec. 4, 2018

Physical activity and sleep duration are established risk factors for many diseases, but their aetiology is poorly understood, partly due to relying on self-reported evidence. Here we report a genome-wide association study (GWAS) of device-measured physical in 91,105 UK Biobank participants, finding 14 significant loci (7 novel). These account 0.06% 0.39% variation. Genome-wide estimates ~ 15% phenotypic variation indicate high polygenicity. Heritability higher women than men overall (23 vs. 20%, p = 1.5 × 10-4) sedentary behaviours (18 15%, 9.7 10-4). partitioning, enrichment pathway analyses the central nervous system plays role behaviours. Two-sample Mendelian randomisation suggests that increased might causally lower diastolic blood pressure (beta mmHg/SD: -0.91, SE 0.18, 8.2 10-7), odds hypertension (Odds ratio/SD: 0.84, 0.03, 4.9 10-8). Our results advocate value reducing pressure.

Language: Английский

Citations

307

The future of sleep health: a data-driven revolution in sleep science and medicine DOI Creative Commons
Ignacio Perez-Pozuelo,

Bing Zhai,

João Palotti

et al.

npj Digital Medicine, Journal Year: 2020, Volume and Issue: 3(1)

Published: March 23, 2020

In recent years, there has been a significant expansion in the development and use of multi-modal sensors technologies to monitor physical activity, sleep circadian rhythms. These developments make accurate monitoring at scale possibility for first time. Vast amounts multi-sensor data are being generated with potential applications ranging from large-scale epidemiological research linking patterns disease, wellness applications, including coaching individuals chronic conditions. However, order realise full these individuals, medicine research, several challenges must be overcome. There important outstanding questions regarding performance evaluation, as well storage, curation, processing, integration, modelling interpretation. Here, we leverage expertise across neuroscience, clinical medicine, bioengineering, electrical engineering, epidemiology, computer science, mHealth human-computer interaction discuss digitisation inter-disciplinary perspective. We introduce state-of-the-art sleep-monitoring technologies, opportunities acquisition eventual application insights consumer settings. Further, explore strengths limitations current emerging sensing methods particular focus on novel data-driven such Artificial Intelligence.

Language: Английский

Citations

231

Association of wearable device-measured vigorous intermittent lifestyle physical activity with mortality DOI Creative Commons
Emmanuel Stamatakis, Matthew Ahmadi, Jason M. R. Gill

et al.

Nature Medicine, Journal Year: 2022, Volume and Issue: 28(12), P. 2521 - 2529

Published: Dec. 1, 2022

Abstract Wearable devices can capture unexplored movement patterns such as brief bursts of vigorous intermittent lifestyle physical activity (VILPA) that is embedded into everyday life, rather than being done leisure time exercise. Here, we examined the association VILPA with all-cause, cardiovascular disease (CVD) and cancer mortality in 25,241 nonexercisers (mean age 61.8 years, 14,178 women/11,063 men) UK Biobank. Over an average follow-up 6.9 during which 852 deaths occurred, was inversely associated all three these outcomes a near-linear fashion. Compared participants who engaged no VILPA, at sample median frequency 3 length-standardized bouts per day (lasting 1 or 2 min each) showed 38%–40% reduction all-cause risk 48%–49% CVD risk. Moreover, duration 4.4 26%–30% 32%–34% We obtained similar results when repeating above analyses for (VPA) 62,344 Biobank exercised (1,552 deaths, 35,290 women/27,054 men). These indicate small amounts nonexercise are substantially lower mortality. appears to elicit effects VPA exercisers, suggesting may be suitable target, especially people not able willing

Language: Английский

Citations

182

Reallocation of time between device-measured movement behaviours and risk of incident cardiovascular disease DOI Creative Commons
Rosemary Walmsley, Shing Chan, Karl Smith-Byrne

et al.

British Journal of Sports Medicine, Journal Year: 2021, Volume and Issue: 56(18), P. 1008 - 1017

Published: Sept. 6, 2021

To improve classification of movement behaviours in free-living accelerometer data using machine-learning methods, and to investigate the association between machine-learned risk incident cardiovascular disease (CVD) adults.

Language: Английский

Citations

108

UK Biobank: a globally important resource for cancer research DOI Creative Commons
Megan Conroy, Ben Lacey,

Jelena Bešević

et al.

British Journal of Cancer, Journal Year: 2022, Volume and Issue: 128(4), P. 519 - 527

Published: Nov. 19, 2022

UK Biobank is a large-scale prospective study with deep phenotyping and genomic data. Its open-access policy allows researchers worldwide, from academia or industry, to perform health research in the public interest. Between 2006 2010, recruited 502,000 adults aged 40-69 years general population of United Kingdom. At enrolment, participants provided information on wide range factors, physical measurements were taken, biological samples (blood, urine saliva) collected for long-term storage. Participants have now been followed up over decade more than 52,000 incident cancer cases recorded. The continues be enhanced repeat assessments, web-based questionnaires, multi-modal imaging, conversion stored other '-omic' has already demonstrated its value enabling into determinants cancer, future planned enhancements will make resource even valuable researchers. Over 26,000 worldwide are currently using data, performing research. uniquely placed transform our understanding causes development progression, drive improvements treatment prevention coming decades.

Language: Английский

Citations

93

Wearable movement-tracking data identify Parkinson’s disease years before clinical diagnosis DOI
Ann‐Kathrin Schalkamp, Kathryn J. Peall, Neil A. Harrison

et al.

Nature Medicine, Journal Year: 2023, Volume and Issue: 29(8), P. 2048 - 2056

Published: July 3, 2023

Language: Английский

Citations

82

Self-supervised learning for human activity recognition using 700,000 person-days of wearable data DOI Creative Commons
Hang Yuan, Shing Chan, Andrew P. Creagh

et al.

npj Digital Medicine, Journal Year: 2024, Volume and Issue: 7(1)

Published: April 12, 2024

Language: Английский

Citations

39