Laser‐Based Selective Material Processing for Next‐Generation Additive Manufacturing DOI Open Access

Huijae Park,

Jung Jae Park,

Phuong‐Danh Bui

et al.

Advanced Materials, Journal Year: 2023, Volume and Issue: 36(34)

Published: Sept. 23, 2023

The connection between laser-based material processing and additive manufacturing is quite deeply rooted. In fact, the spark that started field of idea two intersecting laser beams can selectively solidify a vat resin. Ever since, has been accompanying manufacturing, with its repertoire expanded from only photopolymer resin to virtually any material, allowing liberating customizability. As result, expected take an even more prominent role in global supply chain years come. Herein, overview selective presented various aspects: physics laser-material interactions, materials currently used processes, system configurations enable functional applications next-generation manufacturing. Additionally, current challenges prospects are discussed.

Language: Английский

Trends in Micro‐/Nanorobotics: Materials Development, Actuation, Localization, and System Integration for Biomedical Applications DOI
Ben Wang, Kostas Kostarelos, Bradley J. Nelson

et al.

Advanced Materials, Journal Year: 2020, Volume and Issue: 33(4)

Published: Dec. 4, 2020

Abstract Micro‐/nanorobots (m‐bots) have attracted significant interest due to their suitability for applications in biomedical engineering and environmental remediation. Particularly, vivo diagnosis intervention been the focus of extensive research recent years with various clinical imaging techniques being applied localization tracking. The successful integration well‐designed m‐bots surface functionalization, remote actuation systems, becomes crucial step toward applications, especially uses. This review thus addresses four different aspects m‐bots: design/fabrication, actuation, localization. diagnosis, sensing, microsurgery, targeted drug/cell delivery, thrombus ablation, wound healing are reviewed from these viewpoints. developed m‐bot systems comprehensively compared evaluated based on characteristics. current challenges directions future this field summarized.

Language: Английский

Citations

386

Soft Actuators for Soft Robotic Applications: A Review DOI Creative Commons
Nazek El‐Atab, Rishabh Mishra, Fhad Al‐Modaf

et al.

Advanced Intelligent Systems, Journal Year: 2020, Volume and Issue: 2(10)

Published: Aug. 23, 2020

Soft robotics technologies are paving the way toward robotic abilities which vital for a wide range of applications, including manufacturing, manipulation, gripping, human–machine interaction, locomotion, and more. An essential component in soft robot is actuator provides system with deformable body allows it to interact environment achieve desired actuation pattern, such as locomotion. This Review article aims provide researchers interested field reference guide about various state‐of‐the‐art methodologies that developed stimuli light, heat, applied electric magnetic fields focus on their applications robotics. The underlying principles actuators discussed resulting motion complexities, deformations, multi‐functionalities. Finally, promising examples different addition further development potential.

Language: Английский

Citations

382

Light-driven bimorph soft actuators: design, fabrication, and properties DOI
Yuanhao Chen, Jiajia Yang, Xuan Zhang

et al.

Materials Horizons, Journal Year: 2020, Volume and Issue: 8(3), P. 728 - 757

Published: Oct. 27, 2020

This review provides an account of the state-of-the-art light-driven bimorph soft actuators from their fundamentals to emerging applications, as well new perspectives on future scope, opportunities, and challenges.

Language: Английский

Citations

198

Nanoparticle-modified microrobots for in vivo antibiotic delivery to treat acute bacterial pneumonia DOI
Fangyu Zhang, Jia Zhuang, Zhengxing Li

et al.

Nature Materials, Journal Year: 2022, Volume and Issue: 21(11), P. 1324 - 1332

Published: Sept. 22, 2022

Language: Английский

Citations

198

Drug-Free Antimicrobial Nanomotor for Precise Treatment of Multidrug-Resistant Bacterial Infections DOI

Luntao Liu,

Shuqin Li,

Kaiqiong Yang

et al.

Nano Letters, Journal Year: 2023, Volume and Issue: 23(9), P. 3929 - 3938

Published: April 27, 2023

Manufacturing heteronanostructures with specific physicochemical characteristics and tightly controllable designs is very appealing. Herein, we reported NIR-II light-driven dual plasmonic (AuNR-SiO2-Cu7S4) antimicrobial nanomotors an intended Janus configuration through the overgrowth of copper-rich Cu7S4 nanocrystals at only one high-curvature site Au nanorods (Au NRs). These were applied for photoacoustic imaging (PAI)-guided synergistic photothermal photocatalytic treatment bacterial infections. Both performance activity are dramatically improved owing to strong plasmon coupling between NRs component enhanced energy transfer. The motion behavior promotes transdermal penetration enhances matter–bacteria interaction. More importantly, directional navigation could be synchronously driven by light. marriage active antibacterial resulted in expected good effects abscess infection mouse model.

Language: Английский

Citations

45

Intelligent micro/nanomotors: Fabrication, propulsion, and biomedical applications DOI
Jiamin Ye,

Yueyue Fan,

Gaoli Niu

et al.

Nano Today, Journal Year: 2024, Volume and Issue: 55, P. 102212 - 102212

Published: Feb. 26, 2024

Language: Английский

Citations

19

Biohybrid microrobots locally and actively deliver drug-loaded nanoparticles to inhibit the progression of lung metastasis DOI Creative Commons
Fangyu Zhang, Zhongyuan Guo, Zhengxing Li

et al.

Science Advances, Journal Year: 2024, Volume and Issue: 10(24)

Published: June 12, 2024

Lung metastasis poses a formidable challenge in the realm of cancer treatment, with conventional chemotherapy often falling short due to limited targeting and low accumulation lungs. Here, we show microrobot approach using motile algae for localized delivery drug-loaded nanoparticles address lung challenges. The biohybrid [denoted “algae-NP(DOX)-robot”] combines green microalgae red blood cell membrane–coated containing doxorubicin, representative chemotherapeutic drug. Microalgae provide autonomous propulsion lungs, leveraging controlled drug release enhanced dispersion exert antimetastatic effects. Upon intratracheal administration, algae-NP(DOX)-robots efficiently transport their payload deep into lungs while maintaining continuous motility. This strategy leads rapid distribution, improved tissue accumulation, prolonged retention compared passive free controls. In melanoma model, exhibit substantial improvement therapeutic efficacy, reducing metastatic burden extending survival control groups.

Language: Английский

Citations

18

Engineered Living Systems Based on Gelatin: Design, Manufacturing, and Applications DOI Open Access
Zhenwu Wang, Lin Zeng, Xuan Mei

et al.

Advanced Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 5, 2025

Engineered living systems (ELSs) represent purpose-driven assemblies of components, encompassing cells, biomaterials, and active agents, intricately designed to fulfill diverse biomedical applications. Gelatin its derivatives have been used extensively in ELSs owing their mature translational pathways, favorable biological properties, adjustable physicochemical characteristics. This review explores the intersection gelatin with fabrication techniques, offering a comprehensive examination synergistic potential creating for various applications biomedicine. It offers deep dive into gelatin, including structures production, sources, processing, properties. Additionally, techniques employing derivatives, generic microfluidics, 3D printing methods. Furthermore, it discusses based on regenerative engineering as well cell therapies, bioadhesives, biorobots, biosensors. Future directions challenges are also examined, highlighting emerging trends areas improvements innovations. In summary, this underscores significance gelatin-based advancing lays groundwork guiding future research developments within field.

Language: Английский

Citations

2

Engineered Living Materials: Taxonomies and Emerging Trends DOI Creative Commons
Wil V. Srubar

Trends in biotechnology, Journal Year: 2020, Volume and Issue: 39(6), P. 574 - 583

Published: Nov. 21, 2020

Language: Английский

Citations

99

Biohybrid soft robots with self-stimulating skeletons DOI
Maria Guix, Rafael Mestre, Tania Patiño

et al.

Science Robotics, Journal Year: 2021, Volume and Issue: 6(53)

Published: April 21, 2021

A skeletal muscle–based biobot with a self-stimulating serpentine spring skeleton demonstrates high-performance inertial swimming.

Language: Английский

Citations

99