Marine Drugs,
Journal Year:
2025,
Volume and Issue:
23(2), P. 70 - 70
Published: Feb. 7, 2025
In
recent
years,
the
exploration
of
bioactive
molecules
derived
from
natural
sources
has
gained
interest
in
several
application
fields.
Among
these,
macroalgae
have
garnered
significant
attention
due
to
their
functional
properties,
which
make
them
interesting
therapeutic
applications,
including
cancer
treatment.
Cancer
constitutes
a
global
health
burden,
and
side
effects
existing
treatment
modalities
underscore
necessity
for
novel
models
that,
line
with
goal
reducing
drug
treatments,
take
advantage
compounds.
This
review
explores
anticancer
properties
macroalgae,
focusing
on
compounds
mechanisms
action.
The
key
findings
suggest
that
possess
rich
array
compounds,
polysaccharides
(e.g.,
fucoidans
alginates),
polyphenols
phlorotannins),
terpenoids,
exhibit
diverse
activities,
such
as
inhibition
cell
proliferation,
angiogenesis,
induction
apoptosis,
modulation
immune
system.
provides
an
overview
current
understanding
macroalgae’s
potential,
highlighting
most
promising
While
preclinical
studies
shown
results,
further
research
is
necessary
translate
these
into
effective
clinical
applications.
Bioengineering,
Journal Year:
2022,
Volume and Issue:
9(9), P. 472 - 472
Published: Sept. 14, 2022
The
marine
macroalgae
produce
a
collection
of
bioactive
polysaccharides,
which
the
sulfated
heteropolysaccharide
fucoidan
produced
by
brown
algae
class
Phaeophyceae
has
received
worldwide
attention
because
its
particular
biological
actions
that
confer
nutritional
and
health
benefits
to
humans
animals.
are
determined
their
structure
chemical
composition,
largely
influenced
geographical
location,
harvest
season,
extraction
process,
etc.
This
review
discusses
structure,
composition
physicochemical
properties
fucoidan.
action
applications
for
human
health,
tissue
engineering,
regenerative
medicine
drug
delivery
also
addressed.
industrial
scenario
prospects
research
depicted
would
give
an
insight
into
developing
as
commercially
viable
sustainable
material
in
pharmacological
sectors.
Frontiers in Plant Science,
Journal Year:
2023,
Volume and Issue:
14
Published: March 28, 2023
Natural
antioxidants
are
more
attractive
than
synthetic
chemical
oxidants
because
of
their
non-toxic
and
non-harmful
properties.
Microalgal
bioactive
components
such
as
carotenoids,
polysaccharides,
phenolic
compounds
gaining
popularity
very
effective
long-lasting
natural
antioxidants.
Few
articles
currently
exist
that
analyze
microalgae
from
a
bibliometric
visualization
point
view.
This
study
used
method
based
on
the
Web
Science
Core
Collection
database
to
antioxidant
research
in
1996
2022.
According
cluster
analysis,
most
studied
areas
effectiveness,
mechanism,
use
substances
microalgae,
carotene,
astaxanthin,
tocopherols,
fields
food,
cosmetics,
medicine.
Using
keyword
co-occurrence
mutation
future
trends
predicted
improve
extraction
rates
stability
by
altering
environment
cultures
or
mixing
extracts
with
chemicals
nanoparticles
for
commercial
industrial
applications.
These
findings
can
help
researchers
identify
resources
build
impactful
investigations
expand
scientific
frontiers.
Frontiers in Nutrition,
Journal Year:
2023,
Volume and Issue:
10
Published: July 26, 2023
Brown
seaweeds
are
excellent
sources
of
bioactive
molecules
with
a
wide
range
pharmacological
effects,
whose
content
can
vary
depending
on
several
factors,
including
the
origin
and
environment
in
which
algae
grow.This
study
aimed
to
estimate
19
compounds
regarding
primary
secondary
metabolites
eight
brown
macroalgal
species
from
clean
Egyptian
Red
Sea
coast.
A
proximate
analysis,
pigment,
phenolic
compounds,
vitamin
contents
were
determined.
In
addition,
energy
antioxidant
activity
estimated
explore
potential
application
as
functional
foods
encourage
species'
commercialization.Based
chemical
composition,
Polycladia
myrica
was
most
valuable
species,
comparatively
high
protein
22.54%,
lipid
5.21%,
fucoxanthin
3.12
μg/g,
β-carotene
0.55
mg/100
g,
carbohydrate
45.2%.
This
also
acts
great
source
C,
flavonoids,
tannins,
phenol
total
capacity.The
selected
indicated
that
its
phenol,
pigment
powerful
based
structure-activity
relationships.
result
verified
by
strong
correlation
statistical
analysis
at
95%
confidence
level.
From
worldwide
perspective
obtained
results,
these
may
be
reinforced
an
essential
line
future
foods.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(8), P. 1123 - 1123
Published: April 10, 2024
This
review
delves
into
the
burgeoning
field
of
seaweed
proteins
as
promising
alternative
sources
protein.
With
global
demand
escalating
and
concerns
over
traditional
protein
sources'
sustainability
ethics,
emerges
a
viable
solution,
offering
high
content
minimal
environmental
impacts.
Exploring
nutritional
composition,
extraction
methods,
functional
properties,
potential
health
benefits
proteins,
this
provides
comprehensive
understanding.
Seaweed
contains
essential
amino
acids,
vitamins,
minerals,
antioxidants.
Its
ranges
from
11%
to
32%
dry
weight,
making
it
valuable
for
diverse
dietary
preferences,
including
vegetarian
vegan
diets.
Furthermore,
underscores
advantages
production
compared
sources.
cultivation
requires
resources,
mitigating
issues
like
ocean
acidification.
As
specific
types,
methodologies,
highlights
versatility
in
various
food
products,
plant-based
meats,
dairy
alternatives,
supplements.
Additionally,
discusses
associated
with
such
their
unique
acid
profile
bioactive
compounds.
Overall,
aims
provide
insights
proteins'
applications
role
addressing
needs
sustainably.
Marine Drugs,
Journal Year:
2024,
Volume and Issue:
22(5), P. 226 - 226
Published: May 17, 2024
Utilizing
plant-based
resources,
particularly
their
by-products,
aligns
with
sustainability
principles
and
circular
bioeconomy,
contributing
to
environmental
preservation.
The
therapeutic
potential
of
plant
extracts
is
garnering
increasing
interest,
this
study
aimed
demonstrate
promising
outcomes
from
an
extract
obtained
underutilized
waste.
Chaetomorpha
linum,
invasive
macroalga
found
in
the
Orbetello
Lagoon,
thrives
eutrophic
conditions,
forming
persistent
mats
covering
approximately
400
hectares
since
2005.
biomass
C.
linum
undergoes
mechanical
harvesting
treated
as
waste,
requiring
significant
human
efforts
economic
resources—A
critical
concern
for
municipalities.
Despite
posing
challenges
local
ecosystems,
identified
a
natural
source
bioactive
metabolites.
Phytochemical
characterization
revealed
lipids,
amino
acids,
other
compounds
anti-inflammatory
activity
extract.
In
vitro
assays
LPS-stimulated
RAW
264.7
TNF-α/IFN-γ-stimulated
HaCaT
cells
showed
inhibited
reactive
oxygen
species
(ROS),
nitric
oxide
(NO),
prostaglandin
E2
(PGE2)
productions,
reduced
inducible
synthase
(iNOS)
cyclooxygenase-2
(COX-2)
expressions
via
NF-κB
nuclear
translocation,
cells.
It
also
chemokines
(TARC/CCL17,
RANTES/CCL5,
MCP-1/CCL2,
IL-8)
cytokine
IL-1β
production
cells,
suggesting
candidate
chronic
diseases
like
atopic
dermatitis.
Finally,
silico
studies
indicated
palmitic
acid
contributor
observed
effect.
This
research
not
only
uncovered
untapped
but
laid
foundation
its
integration
into
promoting
sustainable
practices,
innovative
applications
across
various
industries.
