The molecular basis of heterochromatin assembly and epigenetic inheritance DOI Creative Commons
Shiv I. S. Grewal

Molecular Cell, Journal Year: 2023, Volume and Issue: 83(11), P. 1767 - 1785

Published: May 18, 2023

Language: Английский

Advances in epigenetics link genetics to the environment and disease DOI Open Access
Giacomo Cavalli, Édith Heard

Nature, Journal Year: 2019, Volume and Issue: 571(7766), P. 489 - 499

Published: July 1, 2019

Language: Английский

Citations

1207
Genome Regulation by Polycomb and Trithorax: 70 Years and Counting DOI Creative Commons
Bernd Schuettengruber, Henri-Marc Bourbon, Luciano Di Croce

et al.

Cell, Journal Year: 2017, Volume and Issue: 171(1), P. 34 - 57

Published: Sept. 1, 2017

Language: Английский

Citations

990
Ten principles of heterochromatin formation and function DOI
Robin C. Allshire, Hiten D. Madhani

Nature Reviews Molecular Cell Biology, Journal Year: 2017, Volume and Issue: 19(4), P. 229 - 244

Published: Dec. 13, 2017

Language: Английский

Citations

683
Histone post-translational modifications — cause and consequence of genome function DOI
Gonzalo Millán-Zambrano,

Adam Burton,

Andrew J. Bannister

et al.

Nature Reviews Genetics, Journal Year: 2022, Volume and Issue: 23(9), P. 563 - 580

Published: March 25, 2022

Language: Английский

Citations

632
Molecular Mechanisms Directing PRC2 Recruitment and H3K27 Methylation DOI Creative Commons
Anne Laugesen, Jonas W. Højfeldt, Kristian Helin

et al.

Molecular Cell, Journal Year: 2019, Volume and Issue: 74(1), P. 8 - 18

Published: April 1, 2019

Language: Английский

Citations

483
The impact of cellular metabolism on chromatin dynamics and epigenetics DOI
Michael A. Reid, Ziwei Dai, Jason W. Locasale

et al.

Nature Cell Biology, Journal Year: 2017, Volume and Issue: 19(11), P. 1298 - 1306

Published: Oct. 23, 2017

Language: Английский

Citations

444
Functions and mechanisms of epigenetic inheritance in animals DOI
Ksenia Skvortsova, Nicola Iovino, Ozren Bogdanović

et al.

Nature Reviews Molecular Cell Biology, Journal Year: 2018, Volume and Issue: 19(12), P. 774 - 790

Published: Nov. 13, 2018

Language: Английский

Citations

415
Dnmt2 mediates intergenerational transmission of paternally acquired metabolic disorders through sperm small non-coding RNAs DOI
Yunfang Zhang, Xudong Zhang, Junchao Shi

et al.

Nature Cell Biology, Journal Year: 2018, Volume and Issue: 20(5), P. 535 - 540

Published: April 19, 2018

Language: Английский

Citations

383
The molecular principles of gene regulation by Polycomb repressive complexes DOI
Neil P. Blackledge, Robert J. Klose

Nature Reviews Molecular Cell Biology, Journal Year: 2021, Volume and Issue: 22(12), P. 815 - 833

Published: Aug. 16, 2021

Language: Английский

Citations

338
Transgenerational Epigenetic Inheritance DOI
Ana Bošković, Oliver J. Rando

Annual Review of Genetics, Journal Year: 2018, Volume and Issue: 52(1), P. 21 - 41

Published: Aug. 30, 2018

Inheritance of genomic DNA underlies the vast majority biological inheritance, yet it has been clear for decades that additional epigenetic information can be passed on to future generations. Here, we review major model systems transgenerational inheritance via germline in multicellular organisms. In addition surveying examples epivariation may arise stochastically or response unknown stimuli, also discuss induction heritable changes by genetic environmental perturbations. Mechanistically, increasingly well-understood molecular pathways responsible with a focus unusual features epigenome.

Language: Английский

Citations

284