Advanced Healthcare Materials,
Journal Year:
2021,
Volume and Issue:
10(17)
Published: May 29, 2021
Abstract
A
variety
of
electrophysiological
signals
(electrocardiography,
electromyography,
electroencephalography,
etc.)
are
generated
during
the
physiological
activities
human
bodies,
which
can
be
collected
by
electrodes
and
thus
provide
critical
insights
into
health
status
or
facilitate
fundamental
scientific
research.
The
long‐term
stable
high‐quality
recording
is
premise
for
their
further
applications,
leading
to
demands
flexible
with
similar
mechanical
modulus
minimized
irritation
bodies.
This
review
summarizes
latest
advances
in
acquisition
various
signals.
First,
concept
characteristics
different
subcategory
introduced.
Second,
invasive
noninvasive
methods
reviewed
signal
a
highlight
on
design
electrodes,
followed
discussion
material
selection.
Subsequently,
applications
pathological
diagnosis
restoration
body
functions
discussed,
showing
advantages
electrodes.
Finally,
main
challenges
opportunities
this
field
discussed.
It
believed
that
exploration
materials
combination
multidisciplinary
technologies
will
boost
medical
human–machine
interface.
Science,
Journal Year:
2022,
Volume and Issue:
377(6605), P. 517 - 523
Published: July 28, 2022
Continuous
imaging
of
internal
organs
over
days
could
provide
crucial
information
about
health
and
diseases
enable
insights
into
developmental
biology.
We
report
a
bioadhesive
ultrasound
(BAUS)
device
that
consists
thin
rigid
probe
robustly
adhered
to
the
skin
via
couplant
made
soft,
tough,
antidehydrating,
hydrogel-elastomer
hybrid.
The
BAUS
provides
48
hours
continuous
diverse
organs,
including
blood
vessels,
muscle,
heart,
gastrointestinal
tract,
diaphragm,
lung.
diagnostic
monitoring
tools
for
various
diseases.
Science Advances,
Journal Year:
2020,
Volume and Issue:
6(26)
Published: June 24, 2020
Early
processing
of
visual
information
takes
place
in
the
human
retina.
Mimicking
neurobiological
structures
and
functionalities
retina
provides
a
promising
pathway
to
achieving
vision
sensor
with
highly
efficient
image
processing.
Here,
we
demonstrate
prototype
that
operates
via
gate-tunable
positive
negative
photoresponses
van
der
Waals
(vdW)
vertical
heterostructures.
The
emulates
not
only
bipolar
cells
photoreceptors
but
also
unique
connectivity
between
photoreceptors.
By
tuning
gate
voltage
for
each
pixel,
achieve
reconfigurable
simultaneous
sensing
Furthermore,
our
itself
can
be
trained
classify
input
images
by
updating
voltages
applied
individually
pixel
sensor.
Our
work
indicates
vdW
heterostructures
offer
platform
development
neural
network
Nature Communications,
Journal Year:
2021,
Volume and Issue:
12(1)
Published: June 8, 2021
To
understand
the
underlying
mechanisms
of
progressive
neurophysiological
phenomena,
neural
interfaces
should
interact
bi-directionally
with
brain
circuits
over
extended
periods
time.
However,
such
remain
limited
by
foreign
body
response
that
stems
from
chemo-mechanical
mismatch
between
probes
and
tissues.
address
this
challenge,
we
developed
a
multifunctional
sensing
actuation
platform
consisting
multimaterial
fibers
intimately
integrated
within
soft
hydrogel
matrix
mimicking
tissue.
These
hybrid
devices
possess
adaptive
bending
stiffness
determined
hydration
states
matrix.
This
enables
their
direct
insertion
into
deep
regions,
while
minimizing
tissue
damage
associated
micromotion
after
implantation.
The
permit
electrophysiological,
optogenetic,
behavioral
studies
minimal
responses
tracking
stable
isolated
single
neuron
potentials
in
freely
moving
mice
6
months
following
Science Advances,
Journal Year:
2022,
Volume and Issue:
8(13)
Published: March 30, 2022
Intrinsically
stretchable
electronics
represent
an
attractive
platform
for
next-generation
implantable
devices
by
reducing
the
mechanical
mismatch
and
immune
responses
with
biological
tissues.
Despite
extensive
efforts,
soft
electronic
often
exhibit
obvious
trade-off
between
performances
deformability
because
of
limitations
commonly
used
compliant
materials.
Here,
we
introduce
a
scalable
approach
to
create
intrinsically
featuring
deployment
liquid
metal
components
ultrahigh
stretchability
up
400%
tensile
strain
excellent
durability
against
repetitive
deformations.
The
device
architecture
further
shows
long-term
stability
under
physiological
conditions,
conformal
attachments
internal
organs,
low
interfacial
impedance.
Successful
electrophysiological
mapping
on
rapidly
beating
hearts
demonstrates
potential
widespread
applications
in
health
monitoring,
disease
diagnosis,
medical
therapies.
