Psychological Medicine, Journal Year: 2024, Volume and Issue: 54(9), P. 2172 - 2180
Published: Feb. 16, 2024
Early exposure to neighborhood social fragmentation has been shown be associated with schizophrenia. The impact of and friendships on distressing psychotic-like experiences (PLE) remains unknown. We investigate the relationships between fragmentation, number friends, PLE among early adolescents.
Language: Английский
Biological Psychiatry Cognitive Neuroscience and Neuroimaging, Journal Year: 2022, Volume and Issue: 7(11), P. 1149 - 1157
Published: April 14, 2022
Language: Английский
Citations
41
Frontiers in Neuroscience, Journal Year: 2023, Volume and Issue: 17
Published: Feb. 9, 2023
Precision psychiatry has emerged as part of the shift to personalized medicine and builds on frameworks such U.S. National Institute Mental Health Research Domain Criteria (RDoC), multilevel biological “omics” data and, most recently, computational psychiatry. The is prompted by realization that a one-size-fits all approach inadequate guide clinical care because people differ in ways are not captured broad diagnostic categories. One first steps developing this treatment was use genetic markers pharmacotherapeutics based predictions pharmacological response or non-response, potential risk adverse drug reactions. Advances technology have made greater degree specificity precision potentially more attainable. To date, however, search for largely focused parameters. Psychiatric disorders involve multi-level dynamics require measures phenomenological, psychological, behavioral, social structural, cultural dimensions. This points need develop fine-grained analyses experience, self-construal, illness narratives, interpersonal interactional dynamics, contexts determinants health. In paper, we review limitations arguing it cannot reach its goal if does include core elements processes give rise psychopathological states, which agency experience person. Drawing from contemporary systems biology, epidemiology, developmental psychology, cognitive science, propose cultural-ecosocial integrating with person-centered care.
Language: Английский
Citations
30
Annual Review of Clinical Psychology, Journal Year: 2023, Volume and Issue: 19(1), P. 277 - 302
Published: March 8, 2023
The Centers for Disease Control and Prevention has identified racism as a serious threat to public health. Structural is fundamental cause of inequity within interconnected institutions the social environments in which we live develop. This review illustrates how these ethnoracial inequities impact risk extended psychosis phenotype. Black Latinx populations are more likely than White report psychotic experiences United States due determining factors such racial discrimination, food insecurity, police violence. Unless dismantle discriminatory structures, chronic stress biological consequences this race-based trauma will next generation's directly, indirectly through Latina pregnant mothers. Multidisciplinary early interventions show promise improving prognosis, but coordinated care other treatments still need be accessible address racism-specific adversities many people face their neighborhoods environments.
Language: Английский
Citations
29
The Lancet Psychiatry, Journal Year: 2023, Volume and Issue: 10(4), P. 296 - 304
Published: Feb. 22, 2023
Language: Английский
Citations
27
Nature Mental Health, Journal Year: 2023, Volume and Issue: 1(4), P. 273 - 283
Published: April 18, 2023
Language: Английский
Citations
26
Neuroscience & Biobehavioral Reviews, Journal Year: 2024, Volume and Issue: 162, P. 105699 - 105699
Published: May 6, 2024
Robust epidemiological evidence of risk and protective factors for psychosis is essential to inform preventive interventions. Previous syntheses have classified these according their strength association with psychosis. In this critical review we appraise the distinct overlapping mechanisms 25 key environmental psychosis, link mechanistic pathways that may contribute neurochemical alterations hypothesised underlie psychotic symptoms. We then discuss implications our findings future research, specifically considering interactions between factors, exploring universal subgroup-specific improving understanding temporality dynamics, standardising operationalisation measurement developing interventions targeting factors.
Language: Английский
Citations
11
Psychological Medicine, Journal Year: 2025, Volume and Issue: 55
Published: Jan. 1, 2025
Abstract Background Recent research has demonstrated that domains of social determinants health (SDOH) (e.g. air pollution and context) are associated with psychosis. However, SDOHs have often been studied in isolation. This study investigated distinct exposure profiles, estimated their associations persistent distressing psychotic-like experiences (PLE), evaluated whether involvement physical activity partially explains this association. Methods Analyses included 8,145 young adolescents from the Adolescent Brain Cognitive Development Study. Data baseline three follow-ups were included. Area-level geocoded variables spanning various SDOH, including socioeconomic status, education, crime, built environment, context, clustered using a self-organizing map method to identify profiles. Generalized linear mixed modeling tested association between profiles PLE activities (i.e. team individual sports), adjusting for individual-level covariates age, sex, race/ethnicity, highest level parent family-relatedness, sites. Results Five identified. Compared reference Profile 1 (suburban affluent areas), 3 (rural areas low walkability high ozone), 4 (urban SES deprivation, pollution) greater PLE. Team sports mediated 6.14% 3. Conclusions found neighborhoods characterized by rural urban concentrations, crime Findings suggest social-environmental factors may differentially impact development
Language: Английский
Citations
2
Issues in Mental Health Nursing, Journal Year: 2025, Volume and Issue: 46(1), P. 70 - 82
Published: Jan. 2, 2025
The need for belonging is a fundamental human motivation. Despite the significance of belonging, many people struggle to feel sense it. Healthcare organizations continue experience workforce shortages. A workplace that does not promote may prevent career progression its staff, leading low morale and poor work performance. This negatively impact their physical mental health compromise patient safety. purpose was explore inter-professional healthcare workers' at all levels (horizontal vertical) predict possible factors promote/hinder An anonymous, descriptive, cross-sectional online electronic survey design modified version Sense Belonging Instrument were used collect data over 2 months in 2024 report employees' belonging. included nurses. study conducted large, urban, addiction hospital located Ontario, Canada. total 441 staff members completed questionnaire. response rate 24%. variables age, tenure, gender, ethnicity, area work, job satisfaction statistically significant. Multiple regression analysis revealed employment status, predictors leaders must understand who feels they belong not. Every employee (regardless background), should belong. People have like an outsider when are work. Understanding fostering critical maintaining stable workforce.
Language: Английский
Citations
1
SSM - Mental Health, Journal Year: 2025, Volume and Issue: unknown, P. 100392 - 100392
Published: Jan. 1, 2025
Language: Английский
Citations
1
Quality of Life Research, Journal Year: 2025, Volume and Issue: unknown
Published: March 5, 2025
Language: Английский
Citations
1