Therapeutic Strategies and Genetic Implications for Periodontal Disease Management: A Systematic Review

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(13), P. 7217 - 7217

Published: June 29, 2024

The objective of this review is to identify the microbiological alterations caused by various therapy modalities critically analyzing current findings. We limited our search English-language papers published between 1 January 2004 and 7 May 2024 in PubMed, Scopus, Web Science that were relevant topic. In approach, Boolean keywords "microbio*" AND "periodontitis" used. A total 5152 obtained from databases (2205), PubMed (1793), Scopus (1154). This resulted 3266 articles after eliminating duplicates (1886), 1411 entries eliminated their titles abstracts examined. qualitative analysis 22 final included study. Research on periodontal disease shows periodontitis alters oral microbiome increases antibiotic resistance. Treatments like scaling root planing (SRP), especially when combined with minocycline, improve clinical outcomes reducing harmful bacteria. Comprehensive mechanical debridement antibiotics, probiotics, EMD bone grafts, other adjunctive therapies enhances health. Personalized treatment strategies advanced microbial analyses are crucial for effective management resistance control.

Language: Английский

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The Role of Curcumin in Oral Health and Diseases: A Systematic Review

Antioxidants, Journal Year: 2024, Volume and Issue: 13(6), P. 660 - 660

Published: May 28, 2024

Curcumin (Curcumin) belongs to the polyphenol family. It is extracted by drying root of a plant Asian origin, belonging Zingiberaceae The best-known species Curcumincuma Longa. has been recognized as having great therapeutic powers since ancient times. Studies on curcumin have confirmed its powerful antioxidant properties, preventing both formation free radicals and their neutralization, anti-inflammatory, antibacterial, immunological, neuroprotective well being regulator intestinal microbiota with beneficial effects clinical manifestations metabolic syndrome. Our study aimed highlight how all these aspects could benefit oral health, improving course pathological processes. effect mouthwashes, curcumin-based gels regulation bacterial plaque in control gingivitis, was largely comparable that using 0.20% chlorhexidine, fewer side effects. Being highly hydrophobic substance, it high permeability cross cell membrane. Bioavailability increases when combined liposoluble substances (e.g., olive oil) piperine, which improves absorption. also negligible degree toxicity, making an excellent alternative use gold standard products for disinfection.

Language: Английский

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Bidirectional Association between Periodontitis and Thyroid Disease: A Scoping Review

International Journal of Environmental Research and Public Health, Journal Year: 2024, Volume and Issue: 21(7), P. 860 - 860

Published: June 30, 2024

Periodontitis is a chronic inflammatory disease of the tissues surrounding and supporting teeth. Due to development inflammation, periodontitis can contribute several systemic diseases, including thyroid disease. Thyroid pathology includes benign, malignant, autoimmune conditions leading hypothyroidism, hyperthyroidism, or euthyroidism. Alterations in hormones, especially reveal significant oral manifestations, periodontitis. This scoping review aims explore probable causal relationship between disease, terms epidemiology, pathogenesis, treatment. The search strategy follows PRISMA-ScR guidelines. PubMed, Scopus, Web Science, Cochrane were searched from January 2014 2024, entering MESH “periodontitis” “thyroid”. Of 153 initial records, 20 articles selected discussed. There high prevalence among patients with cancer. causes at basis this association are genetic factors, microbiome, proinflammatory cytokines. Periodontal treatment, specifically scaling root planning, ameliorate parameters. Although there few randomized controlled studies literature, lays foundation for bidirectional link which is, once again, inflammation.

Language: Английский

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Diagnosis and Orthodontic Treatment of Obstructive Sleep Apnea Syndrome Children—A Systematic Review

Diagnostics, Journal Year: 2024, Volume and Issue: 14(3), P. 289 - 289

Published: Jan. 29, 2024

Obstructive sleep apnea syndrome (OSAS) is a respiratory illness that associated with recurrent episodes of either partial or full obstruction the upper airways, apnea, among other disorders. This study aims to analyze, through literature review, whether orthodontic treatment can be good strategy for this type disorder. We performed database search on Scopus, Web Science, and Pubmed keywords OSA(S) orthodontics select papers under evaluation. The criteria inclusion were articles related children undergoing an clinical studies case series, excluding systematic reviews, narrative meta-analyses, adult studies, animal models, in vitro studies. screening phase ended selection 16 publications work. RME, rapid maxillary expansion, turned out preferred cases pediatric OSAS. goal procedure increase hard palate’s transverse diameter by reopening mid-palatal suture. Children contraction dental malocclusion typically undergo such have excellent results. However, OSAS multifactorial disorder; it does not seem morphology oral cavity, therefore, always possible cope problem exclusively treatment.

Language: Английский

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Silver Diamine Fluoride in Pediatric Dentistry: Effectiveness in Preventing and Arresting Dental Caries—A Systematic Review

Children, Journal Year: 2024, Volume and Issue: 11(4), P. 499 - 499

Published: April 22, 2024

Background: Tooth decay is considered a global scourge by the World Health Organization (WHO) starting at an early age. In recent years, silver diamine fluoride (SDF) has regained interest, particularly in pediatric dentistry, used to prevent development of carious lesions or arrest their progression. Objective: The aim this study was assess, through systematic review literature, effectiveness SDF, pedodontics, temporary teeth, preventing arresting dental caries. Material and Methods: An electronic search conducted on PubMed, Web Science Scopus. effect SDF both permanent teeth been considered. Results: inclusion criteria identified 16 randomized controlled trials involving patients aged 18 months 13 years followed over period 12–30 months. Conclusions: practical, accessible effective non-invasive way caries teeth. Its application requires regular monitoring. resulting black spot diminished immediate potassium iodide but may affect its effectiveness.

Language: Английский

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Evaluating the success rates and effectiveness of surgical and orthodontic interventions for impacted canines: a systematic review of surgical and orthodontic interventions and a case series

BMC Oral Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 24, 2025

Language: Английский

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Importance of periodontal phenotype in periodontics and restorative dentistry: a systematic review

BMC Oral Health, Journal Year: 2024, Volume and Issue: 24(1)

Published: Jan. 8, 2024

Abstract Background Periodontal phenotype is regarded to be one of the key factors influencing efficacy restorative therapies in dental practice. The objective systematic review was explore importance thin and thick periodontal phenotypes how they affect outcome by looking at a number academic publications from various online databases. Methods Following PRISMA guidelines (Preferred Reporting Items for Systematic Review standards), relevant data will searched retrieved three significant scientific databases, including PubMed, EBSCO, Scopus. articles with full texts that matched keywords published English between 2018 2023 were taken into consideration. Results majorities these based on type their impact treatment outcomes selected. initial search yielded total 530 articles. Only 273 review’s objectives, considered determining eligibility. 20 eligible analysis. Conclusion Understanding anatomical aspects crucial both periodontology dentistry. clinical restorative, prosthetic, orthodontic, surgical, determined large part phenotype, which also plays role failure or success treatments. Trial registration This study protocol registered International Prospective Register Reviews (PROSPERO) dated 16th June ID CRD42023432568.

Language: Английский

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Root Resorption during Orthodontic Treatment with Clear Aligners vs. Fixed Appliances—A Systematic Review

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(2), P. 690 - 690

Published: Jan. 13, 2024

The external apical root resorption that occurs during orthodontic treatment was the focus of this study, using either fixed appliances (FA) or clear aligners (CA). Using Boolean keywords “APICAL ROOT RESORPTION” and “CLEAR ALIGNERS”, study searched PubMed, Scopus, Web Science, with a restriction to English-language publications. A total 50 publications were found by computerized search, but after eliminating duplicates, completing reviews, determining eligibility, only 9 papers could be used in study. In conclusion, (ARR) is frequent consequence tooth movement mainly affects lower incisors, which may compromise success procedure health patient’s teeth. Several variables, including type tooth, have an impact on severity ARR.

Language: Английский

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Celiac Disease-Related Enamel Defects: A Systematic Review

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(5), P. 1382 - 1382

Published: Feb. 28, 2024

Introduction: This systematic review aims to elucidate the intricate correlation between celiac disease (CD) and dental enamel defects (DED), exploring pathophysiological mechanisms, oral health implications, a dentist’s role in early diagnosis. Materials methods: Following PRISMA guidelines, comprehensive search from 1 January 2013 2024 across PubMed, Cochrane Library, Scopus, Web of Science identified 153 publications. After exclusions, 18 studies met inclusion criteria for qualitative analysis. Inclusion involved study types (RCTs, RCCTs, case series), human participants, English language, full-text available. Results: The yielded publications, with meeting Notable findings include high prevalence DED CD patients, ranging 50 94.1%. Symmetrical chronological defects, according Aine’s classification, were predominant, significant associations observed severity defect extent. Conclusions: recognition lesions, particularly through may signal potential even absence gastrointestinal symptoms. Correlations conditions like molar incisor hypomineralization (MIH) emphasize crucial Collaboration dentists gastroenterologists is essential effective monitoring management. consolidates current knowledge, laying groundwork future research promoting interdisciplinary collaboration improved CD-related outcomes. Further large-scale prospective recommended deepen our understanding these issues.

Language: Английский

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Clear Aligners in the Growing Patient: A Systematic Review

Children, Journal Year: 2024, Volume and Issue: 11(4), P. 385 - 385

Published: March 23, 2024

Mixed dentition represents a critical phase in the oral development of pediatric patients, characterized by simultaneous presence primary and permanent teeth. This article proposes comprehensive systematic review application aligners as an innovative methodology managing mixed dentition. The objective is to explore efficacy, safety, acceptability this emerging orthodontic technology evolving age group. focuses on randomized controlled trials, cohorts, observational studies investigating use patients with Clinical, radiographic, psychosocial parameters will be considered assess overall impact aligner therapy dental development. An in-depth analysis such data aims provide overview potential orthodontics. Expected outcomes may contribute outlining practical guidelines targeted therapeutic strategies for orthodontists involved Furthermore, identify gaps current research suggest future directions exploring transparent dentition, thereby contributing ongoing evolution evidence-based practices.

Language: Английский

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