Associated Factors of Sarcopenia in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis

Nutrients, Journal Year: 2021, Volume and Issue: 13(12), P. 4291 - 4291

Published: Nov. 27, 2021

(1) Background: To review the associated factors of sarcopenia in community-dwelling older adults. (2) Methods: PubMed, Embase, Web Science, and four Chinese electronic databases were searched for observational studies that reported from inception to August 2021. Two researchers independently selected literature, evaluated their quality, extracted relevant data. The pooled odds ratio (OR) its 95% confidence interval (CI) calculated each using random-effects/fixed-effects models. Publication bias was assessed funnel plot Eggers test. We performed statistical analysis Stata 15.0 software. (3) Results: A total 68 comprising 98,502 cases included. Sociodemographic among adults included age (OR = 1.12, CI: 1.10-1.13), marital status (singled, divorced, or widowed) 1.57, 1.08-2.28), disability activities daily living (ADL) 1.49, 1.15-1.92), underweight 3.78, 2.55-5.60). Behavioral smoking 1.20, 1.10-1.21), physical inactivity 1.73, 1.48-2.01), malnutrition/malnutrition risk 2.99, 2.40-3.72), long 2.30, 1.37-3.86) short 3.32, 1.86-5.93) sleeping time, alone 1.55, 1.00-2.40). Disease-related diabetes 1.40, 1.18-1.66), cognitive impairment 1.62, 1.05-2.51), heart diseases 1.14, 1.00-1.30), respiratory 1.22, 1.09-1.36), osteopenia/osteoporosis 2.73, 1.63-4.57), osteoarthritis 1.33, 1.23-1.44), depression 1.46, 1.17-1.83), falls 1.28, 1.14-1.44), anorexia 1.50, 1.14-1.96), anemia 1.39, 1.06-1.82). However, it remained unknown whether gender (female: OR 1.10, 0.80-1.51; male: 0.96-2.34), overweight/obesity 0.27, 0.17-0.44), drinking 0.92, 0.84-1.01), hypertension 0.98, 0.84-1.14), hyperlipidemia 0.89-1.47), stroke 1.70, 0.69-4.17), cancer 0.88, 0.85-0.92), pain 1.08, 0.98-1.20), liver disease 0.85-0.91), kidney 2.52, 0.19-33.30) with sarcopenia. (4) Conclusions: There are many sociodemographic, behavioral, disease-related Our view provides evidence early identification high-risk individuals development interventions prevent

Language: Английский

---

Molecular Mechanisms of Inflammation in Sarcopenia: Diagnosis and Therapeutic Update

Cells, Journal Year: 2022, Volume and Issue: 11(15), P. 2359 - 2359

Published: Aug. 1, 2022

Sarcopenia is generally an age-related condition that directly impacts the quality of life. It also related to chronic diseases such as metabolic dysfunction associated with diabetes and obesity. This means everyone will be vulnerable sarcopenia at some point in their Research find precise molecular mechanisms implicated this can increase knowledge for better prevention, diagnosis, treatment sarcopenia. Our work gathered most recent research regarding inflammation new therapeutic agents proposed target its consequences pyroptosis cellular senescence. Finally, we compared dual X-ray absorptiometry (DXA), magnetic resonance imaging (MRI), ultrasound (US) techniques diagnose follow up on sarcopenia, indicating respective advantages disadvantages. goal scientific evidence presented here help guide future understand involved strategies, translation into clinical practice.

Language: Английский

---

Association of physical behaviours with sarcopenia in older adults: a systematic review and meta-analysis of observational studies

The Lancet Healthy Longevity, Journal Year: 2024, Volume and Issue: 5(2), P. e108 - e119

Published: Feb. 1, 2024

BackgroundPhysical behaviours (ie, physical activity and sedentary behaviour) might have a role in the development of sarcopenia, although evidence is unclear. We aimed to explore association total intensity-specific levels behaviour with sarcopenia its components muscle mass, strength, performance) older adults.MethodsWe conducted systematic review meta-analysis searched MEDLINE (via PubMed), Scopus, Web Science from inception July 26, 2022, for peer-reviewed, observational studies or baseline data randomised clinical trials adults individual age ≥60 years mean ≥65 years) published English that reported on both (or determinants: mass performance). Physical were measured by any method. The main outcome was which could be diagnosed means. Estimates extracted pooled using Bayesian meta-analytic models publication bias assessed Egger's test. This study registered PROSPERO, CRD42022315865.FindingsWe identified 15 766 records, 124 (230 174 adults; 121 301 [52·7%] female 108 873 [47·3%] male) included review. 86 subsequently meta-analysis. Higher inversely associated cross-sectionally (21 studies, n=59 572; odds ratio 0·49, 95% credible interval 0·37–0·62) longitudinally (four n=7545; 0·51, 0·27–0·94). A protective also moderate-to-vigorous cross-sectional research (five n=6787; 0·85, 0·71–0·99), whereas no remaining steps, light activity, behaviour).InterpretationTotal are sarcopenia. These findings support importance moderate-to-vigorous, rather than light, intensity activity-based interventions prevent sarcopenia.FundingNone.TranslationFor Spanish translation abstract see Supplementary Materials section.

Language: Английский

---

Sleep Duration and Sarcopenia: An Updated Systematic Review and Meta-Analysis

Journal of the American Medical Directors Association, Journal Year: 2023, Volume and Issue: 24(8), P. 1193 - 1206.e5

Published: June 7, 2023

In adults, short and long sleep duration has been associated with sarcopenia risk. Studies have shown that various factors, including biological psychological could be the underlying cause of association between aberrant this study, we qualitatively quantitatively summarized previously published studies on to assess relationship risk in adults. This would aid enhancing our understanding recent advancements field risk.Systematic review meta-analysis.In review, included evaluating adults observational studies.Five electronic databases (PubMed, EMBASE, Cochrane Library, China National Knowledge Infrastructure, Web Science) were searched April 20, 2023, identify related duration. Next, calculated odds ratios (ORs) for prevalence based adjusted data from individual studies. Statistical analyses performed using Stata 11.0.Sarcopenia was high (18%) Our results showed a significant older (OR 1.2, 95% CI 1.02-1.41, I2 = 56.6%). Furthermore, observed all participants long-duration 1.53, 1.34-1.75, 56.8%). We also heterogeneity ORs.There correlation or duration, especially sleep, relatively high.

Language: Английский

---

Lifestyle approaches to prevent and retard sarcopenia: A narrative review

Maturitas, Journal Year: 2022, Volume and Issue: 161, P. 44 - 48

Published: Feb. 25, 2022

Language: Английский

---

The association between sleep parameters and sarcopenia in Japanese community-dwelling older adults

Archives of Gerontology and Geriatrics, Journal Year: 2023, Volume and Issue: 109, P. 104948 - 104948

Published: Jan. 31, 2023

This study aimed to examine the association between sleep duration and quality sarcopenia, assessed by factors such as low muscle mass (LMM), strength (LMS), physical performance (LPP) among older community-dwellers in Japan. In this cross-sectional study, a total of 2,069 (men, 902; women, 1,167) participants aged 65 80 years were included. Sarcopenia each function defined using definitions Asian Working Groups 2019. Sleep was stratified into three categories: short (<6 h), normal (6-8 long (>8 h). classified two groups based on 8-item Athens Insomnia Scale score: insomnia (≥6), non-insomnia (<6). We analyzed parameters including functions, logistic regression analysis. Compared sleepers, sleepers had positive with sarcopenia (odds ratio [OR] 2.11, 95% confidence interval [CI] 1.25-3.58). particular, strongly associated LMS (OR 1.77, 95%CI 1.07-2.94) LPP 1.90, 1.25-2.88). On other hand, poor not but sleepers. Long LPP. However, or any its components.

Language: Английский

---

The association between sedentary behaviour and sarcopenia in older adults: a systematic review and meta-analysis

BMC Geriatrics, Journal Year: 2023, Volume and Issue: 23(1)

Published: Dec. 20, 2023

Abstract Background Sedentary behaviour is considered to contribute sarcopenia when combined with physical inactivity. Whether sedentary independently associated remains controversial. The aim of this study explore the association between and in older adults community long-term care facility settings. Methods Eight electronic databases including MEDLINE, PsycINFO, Wanfang were searched from inception until August 2023. review included cross-sectional longitudinal studies concerning among participants over 60 years old. Evidence was pooled by both random-effects meta-analysis narrative synthesis. Subgroup analyses explored variation according adjustment activity, settings, measurements sarcopenia. Quality assessment for individual performed Joanna Briggs Institute (JBI) Critical Appraisal Checklist. Results Seventeen articles (16 1 study) 25,788 or settings included. overall quality rated high. Meta-analysis 14 showed that positively sarcopenia: odd ratio 1.36 (95% confidence interval, 1.18–1.58). independent positive remained subgroup analysis corroborated findings provided additional evidence suggesting interruptions periods linked a decreased likelihood developing Conclusions support hypothesis adults, providing vital indications development strategies prevent Systematic registration systematic protocol has been registered PROSPERO database (CRD42022311399).

Language: Английский

---

Impact of Malnutrition Status on Muscle Parameter Changes over a 5-Year Follow-Up of Community-Dwelling Older Adults from the SarcoPhAge Cohort

Nutrients, Journal Year: 2021, Volume and Issue: 13(2), P. 407 - 407

Published: Jan. 28, 2021

This study aimed to assess the impact of malnutrition on 5-year evolution physical performance, muscle mass and strength in participants from SarcoPhAge cohort, consisting community-dwelling older adults. The status was assessed at baseline (T0) according “Global Leadership Initiatives Malnutrition” (GLIM) criteria, parameters were evaluated both T0 after five years follow-up (T5). Lean mass, performance using dual X-ray absorptiometry, handgrip dynamometry, short battery test timed up go test, respectively. Differences outcomes nutritional tested Student’s t-test. association between relative change multiple linear regressions adjusted for several covariates. A total 411 (mean age 72.3 ± 6.1 years, 56% women) included. Of them, 96 individuals (23%) diagnosed with baseline. Their significantly lower than those well-nourished patients (all p-values < 0.05), except women T5, which not presence malnutrition. However, changes malnourished different > 0.05).

Language: Английский

---

Physical Activity, Sedentary Behavior, Fruit and Vegetable Consumption, and Sarcopenia in Older Chinese Adults: A Cross-Sectional Study

Nutrients, Journal Year: 2023, Volume and Issue: 15(15), P. 3417 - 3417

Published: Aug. 1, 2023

The purpose of this study was to investigate the association between moderate vigorous physical activity (MVPA), sedentary behavior, fruit and vegetable intake, risk sarcopenia among older Chinese adults. This cross-sectional enrolled 5418 adults who participated in Study on Global Aging Adult Health (SAGE). Participants reported information about their activity, dietary habits (fruit intake). Sarcopenia defined as presence low skeletal muscle mass either a slow gait speed or weak handgrip strength. A multiple logistic regression model employed determine relationship MVPA, sarcopenia. Only 32.63% participants met all three recommendations (for Compared with meeting none recommendations, associated lower (OR = 0.63, 95% CI 0.41-0.98). Moreover, recommendation for sufficient intake 0.69, 0.58-0.83), MVPA fruit/vegetable 0.67, 0.52-0.86), behavior 0.48-0.98) Our findings indicate that large representative sample adults, lifestyle protected against

Language: Английский

---

Association of Daily Sitting Time and Leisure-Time Physical Activity with Sarcopenia Among Chinese Older Adults

Healthcare, Journal Year: 2025, Volume and Issue: 13(3), P. 251 - 251

Published: Jan. 27, 2025

Objectives: This study aimed to explore the independent and joint associations of daily sitting time leisure-time physical activity (LTPA) with sarcopenia among older adults. Methods: The participants were 847 community-dwelling adults aged 60 or from Beijing Shanghai, China. Sarcopenia was diagnosed based on criteria established by Asian Working Group for (2019). Daily LTPA self-reported using Physical Activity Scale Elderly (PASE). Logistics regression models used between time, LTPA, sarcopenia. To examine associations, classified levels. Final adjusted sociodemographic variables, lifestyle factors, chronic conditions. Results: Prolonged insufficient independently associated higher odds Among insufficiently active participants, 1–2 h, 2–4 more than 4 h per day 5.52-fold (95% CI: 1.13–26.83), 6.69-fold 1.33–33.59), 12.82-fold 2.75–59.85) increased sarcopenia, respectively, compared less 1 h. For those meeting guideline (≥150 min week), only significantly (OR: 7.25, 95% 1.99–26.36). Conclusions: sedentary behavior may not be offset achieving recommended levels activity.

Language: Английский

---