Journal Of Advanced Zoology,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Jan. 1, 2024
Skin
injuries,
whether
due
to
trauma,
burns,
or
chronic
wounds,
present
a
significant
clinical
challenge,
highlighting
the
need
for
innovative
regenerative
therapies.
This
study
focuses
on
development
and
formulation
of
drug-loaded
hydrogel
as
promising
approach
skin
regeneration.
Hydrogel
is
designed
provide
supportive
environment
cell
proliferation,
migration,
differentiation,
while
also
delivering
therapeutic
agents
accelerate
wound
healing.
Various
biocompatible
polymers
crosslinking
methods
are
explored
optimize
hydrogel's
mechanical
properties,
biodegradability,
drug
release
kinetics.
Additionally,
investigates
efficacy
different
drugs,
growth
factors,
bioactive
molecules
in
promoting
angiogenesis,
collagen
synthesis,
tissue
remodeling
within
scaffold.
The
developed
holds
great
potential
addressing
wide
range
injuries
advancing
field
dermatology.
In
summary,
hydrogels
represent
avenue
medicine
their
unique
properties
that
support
repair,
delivery,
healing
processes.
Ongoing
research
continues
explore
applications
address
challenges
regeneration
treatment
effectively.
ACS Applied Bio Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: April 10, 2024
Traditional
tissue
engineering
methods
face
challenges,
such
as
fabrication,
implantation
of
irregularly
shaped
scaffolds,
and
limited
accessibility
for
immediate
healthcare
providers.
In
situ
bioprinting,
an
alternate
strategy,
involves
direct
deposition
biomaterials,
cells,
bioactive
factors
at
the
site,
facilitating
on-site
fabrication
intricate
tissue,
which
can
offer
a
patient-specific
personalized
approach
align
with
principles
precision
medicine.
It
be
applied
using
handled
device
robotic
arms
to
various
tissues,
including
skin,
bone,
cartilage,
muscle,
composite
tissues.
Bioinks,
critical
components
bioprinting
that
support
cell
viability
development,
play
crucial
role
in
success
bioprinting.
This
review
discusses
techniques,
materials
used
bioinks,
their
properties
successful
applications.
Finally,
we
discuss
challenges
future
trends
accelerating
printing
translate
this
technology
clinical
settings
regenerative
Materials & Design,
Journal Year:
2024,
Volume and Issue:
243, P. 113091 - 113091
Published: June 14, 2024
Amidst
the
rapid
advancements
in
materials
science,
exploration
of
aerogel-based
biomaterials
has
garnered
extensive
attention
across
diverse
sectors,
including
biomedicine,
energy,
architecture,
and
sensing.
Comprehensive
studies
have
unveiled
utilization
organic,
inorganic,
hybridized
for
aerogel
preparation,
catapulting
to
global
prominence.
Endowed
with
distinctive
properties,
low
density,
a
hierarchical
porous
network,
high
porosity,
nanoscale
micropores,
aerogels
exhibited
broad
spectrum
applications,
particularly
realm
tissue
engineering.
The
deployment
engineering
is
dynamic
phase
development,
available
reports
indicating
varying
degrees
fields
such
as
blood
vessels,
soft
tissues,
nerves,
skin,
muscles,
heart,
bronchial
tubes,
bone,
cartilage—an
evolutionary
process.
This
paper
offers
comprehensive
review
evolution
properties
preparation
processes,
encapsulating
strategic
insights
application
It
succinctly
summarizes
recent
developments
research,
emphasizing
their
significance.
Additionally,
outlines
future
prospects
envisions
challenges
arising
from
current
studies.
Through
this
thorough
engineering,
aspires
make
profound
impact
on
regenerative
medicine,
offering
innovative
effective
strategies
biomedicine.
International Journal of Extreme Manufacturing,
Journal Year:
2024,
Volume and Issue:
7(1), P. 012009 - 012009
Published: Oct. 16, 2024
Abstract
This
comprehensive
review
explores
the
multifaceted
landscape
of
skin
bioprinting,
revolutionizing
dermatological
research.
The
applications
bioprinting
utilizing
techniques
like
extrusion-,
droplet-,
laser-
and
light-based
methods,
with
specialized
bioinks
for
biofabrication
have
been
critically
reviewed
along
intricate
aspects
hair
follicles,
sweat
glands,
achieving
pigmentation.
Challenges
remain
need
vascularization,
safety
concerns,
integration
automated
processes
effective
clinical
translation.
further
investigates
incorporation
biosensor
technologies,
emphasizing
their
role
in
monitoring
enhancing
wound
healing
process.
While
highlighting
remarkable
progress
field,
critical
limitations
concerns
are
examined
to
provide
a
balanced
perspective.
synthesis
aims
guide
scientists,
engineers,
healthcare
providers,
fostering
deeper
understanding
current
state,
challenges,
future
directions
transformative
tissue
engineering
regenerative
medicine.
Gels,
Journal Year:
2023,
Volume and Issue:
9(5), P. 375 - 375
Published: May 1, 2023
Flavonoids
and
polyphenolic
compounds
play
a
key
role
in
wound
healing
cycle
modulation.
Propolis,
natural
bee
product,
has
been
widely
reported
as
an
enriched
source
of
polyphenols
flavonoids
important
chemical
constituents
for
its
potential.
The
goal
this
study
was
to
develop
characterize
propolis-based
polyvinyl
alcohol
(PVA)
hydrogel
composition
with
To
understand
the
impacts
critical
material
attributes
process
parameters,
formulation
development
carried
out
using
design
experiment
approach.
A
preliminary
phytochemical
analysis
Indian
propolis
extract
showed
presence
(23.61
±
0.0452
mg
equivalent
quercetin/g)
(34.82
0.0785
gallic
acid/g),
both
which
aid
skin
tissue
regeneration.
pH,
viscosity,
vitro
release
were
also
studied.
burn
model
results
revealed
significant
(p
<
0.0001)
contraction
by
(93.58
+
0.15%)
rapid
re-epithelialization
relative
5%
w/w
povidone
iodine
ointment
USP
(Cipladine®)
(95.39
0.16%).
excision
confirms
(91.45
0.29%)
accelerated
comparable
(94.38
0.21%).
developed
offers
promise
healing,
may
be
investigated
further
clinical
research.
