Influence of COVID-19 pandemic and vaccination on the menstrual cycle: A retrospective study in Hungary DOI Creative Commons

Klaudia Barabás,

Bernadett Makkai, Nelli Farkas

et al.

Frontiers in Endocrinology, Journal Year: 2022, Volume and Issue: 13

Published: Oct. 27, 2022

Observations of women and clinicians indicated that the prevalence menstrual cycle problems has escalated during COVID-19 pandemic. However, it was not clear whether observed changes were related to vaccination, disease itself or pandemic-induced psychological alterations. To systematically analyze this question, we conducted a human online survey in aged between 18 65 Hungary. The 1563 individuals analyzed our study relation infection, pandemic mental health. We found no association vaccine types infection changes. also evaluated alterations focusing on three parameters including length, menses length regularity phases: pre-peak, peak post-peak period Our finding did change any periods. increased, while decreased significantly when comparing pre- In addition, exhibited both correlated with severity depression period, therefore concluded reported abnormalities Hungary might be result elevated depressive symptoms.

Language: Английский

SARS-CoV-2, fertility and assisted reproduction DOI Creative Commons
Barış Ata, Nathalie Vermeulen, Edgar Mocanu

et al.

Human Reproduction Update, Journal Year: 2022, Volume and Issue: 29(2), P. 177 - 196

Published: Nov. 14, 2022

In 2020, SARS-CoV-2 and the COVID-19 pandemic had a huge impact on access to provision of ART treatments. Gradually, knowledge virus its transmission has become available, allowing activities resume. Still, questions human gametes fertility remain.

Language: Английский

Citations

82
A retrospective case-control study on menstrual cycle changes following COVID-19 vaccination and disease DOI Creative Commons
Alexandra Alvergne, Gabriella Kountourides,

M. Austin Argentieri

et al.

iScience, Journal Year: 2023, Volume and Issue: 26(4), P. 106401 - 106401

Published: March 15, 2023

There has been increasing public concern that COVID-19 vaccination causes menstrual disturbance regarding the relative effect of compared to SARS-CoV-2 infection. Our objectives were test potential risk factors for reporting cycle changes following and compare parameters disease. We performed a secondary analysis retrospective online survey conducted in UK March 2021. In pre-menopausal vaccinated participants (n = 4,989), 18% reported after their first vaccine injection. The prevalence any was higher women who smoke, have history disease, or are not using estradiol-containing contraceptives. second sample including both unvaccinated 12,579), alone associated with abnormal parameters, while disease an increased heavier bleeding, "missed" periods, inter-menstrual bleeding.

Language: Английский

Citations

71
Menstrual abnormalities after COVID-19 vaccines: A systematic review DOI
Maheen Nazir,

Shumaila Asghar,

Muhammad Ali Rathore

et al.

Vacunas, Journal Year: 2022, Volume and Issue: 23, P. S77 - S87

Published: July 19, 2022

Language: Английский

Citations

67
Covid-19 vaccination and menstrual cycle length in the Apple Women’s Health Study DOI Creative Commons
Elizabeth A. Gibson, Huichu Li, Victoria Fruh

et al.

npj Digital Medicine, Journal Year: 2022, Volume and Issue: 5(1)

Published: Nov. 2, 2022

COVID-19 vaccination may be associated with change in menstrual cycle length following vaccination. We estimated covariate-adjusted differences mean (MCL), measured days, between pre-vaccination cycles, and post-vaccination cycles within vaccinated participants who met eligibility criteria the Apple Women's Health Study, a longitudinal mobile-application-based cohort of people U.S. manually logged cycles. A total 9652 (8486 vaccinated; 1166 unvaccinated) contributed 128,094 (median = 10 per participant; inter-quartile range: 4-22). Fifty-five percent received Pfizer-BioNTech's mRNA vaccine, 37% Moderna's 8% Johnson & Johnson/Janssen (J&J) vaccine. was small increase MCL for which first dose (0.50 95% CI: 0.22, 0.78) second (0.39 0.11, 0.67) vaccines compared Cycles single J&J administered were, on average, 1.26 days longer (95% 0.45, 2.07) than Post-vaccination returned to average length. Estimated follicular phase increased (0.97 0.53, 1.42) or (1.43 1.06, 1.80) (2.27 1.04, 3.50), Menstrual appears temporary should not discourage individuals from becoming vaccinated.

Language: Английский

Citations

53
Brain fog in menopause: a health-care professional’s guide for decision-making and counseling on cognition DOI
Pauline M. Maki, Nicole G. Jaff

Climacteric, Journal Year: 2022, Volume and Issue: 25(6), P. 570 - 578

Published: Sept. 30, 2022

Midlife women commonly experience changes in their cognitive function as they transition through menopause and express concern about whether these represent the initial stages of a more serious disorder. Health-care practitioners play an important role counseling on at midlife normalizing women's experience. The aim this commissioned International Menopause Society White Paper cognition is to provide with overview data informing clinical care menopausal framework for decision-making. Among topics presented are specific occurring menopause, duration such severity. estrogen symptoms reviewed. We present talking points effects hormone therapy dementia risk women, including discussion absolute risk. Lastly, brief review modifiable factors age-related decline presented, guidance patients optimizing brain health beyond.

Language: Английский

Citations

49
Menstrual Changes after COVID-19 Infection and COVID-19 Vaccination DOI Creative Commons
Işılay Taşkaldıran, Emre Vuraloğlu, Yusuf Bozkuş

et al.

International Journal of Clinical Practice, Journal Year: 2022, Volume and Issue: 2022, P. 1 - 5

Published: Oct. 27, 2022

Several factors such as stress, depression, infection, and vaccination influenced the menstrual cycle in women during coronavirus disease 2019 (COVID-19) pandemic. We investigated whether there were changes after COVID-19 or infection and, if so, nature of change.This study was designed a descriptive, cross-sectional study. A face-to-face survey conducted among menstruating aged 18-50 years from May 31 to July 31, 2022. Women inquired about their first three cycles that occurred vaccination.Of 241 with 86 (35.7%) mentioned they experienced various patterns infection. Of 537 participants who received vaccines, 82 (15.1%) stated vaccination. The incidence postvaccination change higher Pfizer-BioNTech Sinovac (CoronaVac) vaccines. Only 10.9% reported pattern consulted physician.COVID-19 can affect women. It is important be aware warn inform this issue.

Language: Английский

Citations

32
COVID-19 vaccination and menstrual cycle characteristics: A prospective cohort study DOI Creative Commons
Amelia K. Wesselink, Sharonda M. Lovett, Janice Weinberg

et al.

Vaccine, Journal Year: 2023, Volume and Issue: 41(29), P. 4327 - 4334

Published: June 1, 2023

Language: Английский

Citations

20
Association between COVID-19 vaccination and menstruation: a state of the science review DOI
Laura A. Payne, Lauren A. Wise, Amelia K. Wesselink

et al.

BMJ Sexual & Reproductive Health, Journal Year: 2024, Volume and Issue: 50(3), P. 212 - 225

Published: June 10, 2024

Menstrual health is a key patient-reported outcome beyond its importance as general indicator of and fertility. However, menstrual function was not measured in the clinical trials COVID-19 vaccines. The purpose this review to synthesise existing literature on relationship between vaccination outcomes.

Language: Английский

Citations

9
Menstrual Changes Following COVID-19 Vaccination: A Cross-Sectional Study DOI Creative Commons

Nahid Ibrahim Fallatah,

Bushra Omar Alrehaili,

Salhah Alsulami

et al.

Medicina, Journal Year: 2024, Volume and Issue: 60(2), P. 206 - 206

Published: Jan. 25, 2024

Background and Objectives: Menstrual changes, including altered cycle length bleeding patterns, have been reported following COVID-19 vaccination. This study aimed to determine the prevalence types of menstrual changes occurring after vaccination among female students staff at a university in Saudi Arabia. Materials Methods: A cross-sectional was conducted women aged 18–39 years who received least one dose vaccine. Eligible participants, staff, were recruited between May 2022 November 2022. Participants completed questionnaire detailing their sociodemographic characteristics, general medical reproductive history, characteristics before The various (cycle length, days, flow, mid-cycle spotting) calculated. demographic factors associated with analyzed using chi-squared tests. Results: 472 included participants had mean age 20.9 years, 95.3% unmarried. Changes by 54.7% respondents overall. most common change followed number menstruation days flow. not age, BMI, occupation, marital status, or history. intermenstrual more frequently third Pfizer vaccine compared Moderna (p = 0.014). Conclusions: More than half vaccination, being common. potential underlying mechanisms implications these alterations require further investigation. These findings provide evidence side effects vaccines

Language: Английский

Citations

8
Messenger RNA Therapy for Female Reproductive Health DOI

Rachel VanKeulen‐Miller,

Owen S. Fenton

Molecular Pharmaceutics, Journal Year: 2024, Volume and Issue: 21(2), P. 393 - 409

Published: Jan. 8, 2024

Female reproductive health has traditionally been an underrepresented area of research in the drug delivery sciences. This disparity is also seen emerging field mRNA therapeutics, a class medicines that promises to treat and prevent disease by upregulating protein expression body. Here, we review advances therapies through lens improving female health. Specifically, begin our discussing fundamental structure biochemical modifications associated with mRNA-based drugs. Then, discuss various packaging technologies, including lipid nanoparticles, can be utilized protect transport drugs target cells Last, conclude usage therapy for addressing pregnancy-related vaccination against sexually transmitted diseases women. Of note, highlight relevant clinical trials using while providing their corresponding National Clinical Trial identifiers. In undertaking this review, aim provide background understanding its specifically address issues overarching goal information toward gender certain aspects research.

Language: Английский

Citations

7