Long COVID, a comprehensive systematic scoping review

Infection, Journal Year: 2021, Volume and Issue: 49(6), P. 1163 - 1186

Published: July 28, 2021

Language: Английский

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More Than 100 Persistent Symptoms of SARS-CoV-2 (Long COVID): A Scoping Review

Frontiers in Medicine, Journal Year: 2021, Volume and Issue: 8

Published: Nov. 1, 2021

Background: Persistent coronavirus disease 2019 (COVID-19) symptoms are increasingly well-reported in cohort studies and case series. Given the spread of pandemic, number individuals suffering from persistent symptoms, termed ‘long COVID', significant. However, type prevalence not well reported using systematic literature reviews. Objectives: In this scoping review literature, we aggregated people with long COVID. Eligibility Criteria: Original investigations concerning name were considered participants ≥4-weeks post-infection. Sources Evidence: Four electronic databases [Medline, Web Science, Scopus, Cochrane Central Register Controlled Trials (CENTRAL)] searched. Methods: A was conducted Arksey O'Malley framework. Review selection characterisation performed by three independent reviewers pretested forms. Results: Authors reviewed 2,711 titles abstracts for inclusion 152 selected full-text review. 102 articles subsequently removed as did meet criteria. Thus, fifty analysed, 34 which described or prospective studies, 14 cross-sectional one a control study, retrospective observational study. total, >100 identified there considerable heterogeneity symptom setting Ten cardiovascular four examined pulmonary 25 respiratory 24 pain-related 21 fatigue, 16 general infection 10 psychological disorders, nine cognitive impairment, 31 sensory seven dermatological complaint, 11 functional 18 fit into any above categories. Conclusion: Most report analogous to those apparent acute COVID-19 (i.e., impairment symptoms). Yet, our data suggest larger spectrum evidenced symptoms. Symptom varied significantly explained collection approaches, study design other methodological may be related unknown cohort-specific factors.

Language: Английский

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Beneficial effects of multi-disciplinary rehabilitation in postacute COVID-19: an observational cohort study

European Journal of Physical and Rehabilitation Medicine, Journal Year: 2021, Volume and Issue: 57(2)

Published: May 1, 2021

The Coronavirus Disease 2019 (COVID-19) pandemic increases the demand for postacute care in patients after a severe disease course. Various long-term sequelae are expected and rehabilitation medicine is challenged to support physical cognitive recovery.We aimed explore dysfunctions outcome of COVID-19 survivors early rehabilitation.Observational cohort study.This study evaluated hospitalized SARS-CoV-2 infection analyzed rehabilitative outcomes subgroup included prospective observational multicenter CovILD study.A total 23 subjects discharged critical underwent an individualized, multiprofessional rehabilitation. At start rehabilitation, impairment pulmonary function (87%), symptoms related postintensive syndrome, neuropsychological dysfunction (85%) were frequently found, whereas cardiac appeared be largely unaffected. Of interest, multi-disciplinary resulted significant improvement lung function, as reflected by increase forced vital capacity (P=0.007) expiratory volume one second (P=0.014), (P=0.003), diffusion carbon monoxide (P=0.002). Accordingly, performance status significantly improved mean six-minute walking distance 176 (SD±137) meters. Contrarily, considerable proportion still had limited (83%) or neurological including peripheral neuropathy at end rehabilitation.Individuals course present with persisting hospital discharge. Those benefit from inpatient rehabilitation.Our data demonstrated highly promising effects COVID-19. This findings urge further evaluations may impact future treatment strategies.

Language: Английский

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European Respiratory Society statement on long COVID follow-up

European Respiratory Journal, Journal Year: 2022, Volume and Issue: 60(2), P. 2102174 - 2102174

Published: Feb. 10, 2022

Patients diagnosed with coronavirus disease 2019 (COVID-19) associated severe acute respiratory syndrome 2 (SARS-CoV-2) infection frequently experience symptom burden post-acute or post-hospitalisation. We aimed to identify optimal strategies for follow-up care that may positively impact the patient's quality of life (QoL). A European Respiratory Society (ERS) Task Force convened and prioritised eight clinical questions. targeted search literature defined timeline “long COVID” as 1–6 months post-infection identified evidence in patients. Studies meeting inclusion criteria report an association characteristics persistent symptoms, thromboembolic events period, evaluations pulmonary physiology imaging. Importantly, this statement reviews QoL consequences, burden, disability home follow-up. Overall, patients long COVID is limited.

Language: Английский

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Pulmonary Rehabilitation in a Post-COVID-19 World: Telerehabilitation as a New Standard in Patients with COPD

International Journal of COPD, Journal Year: 2021, Volume and Issue: Volume 16, P. 379 - 391

Published: Feb. 1, 2021

Abstract: Pulmonary rehabilitation (PR) is effective in reducing symptoms and improving health status, exercise tolerance of patients with chronic obstructive pulmonary disease (COPD). The coronavirus 19 (COVID-19) pandemic has greatly impacted PR programs their delivery to patients. Owing fears viral transmission resultant outbreaks COVID-19, institution-based have been forced significantly reduce enrolment or some cases completely shut down during the pandemic. As a majority COPD are elderly multiple co-morbidities including cardiovascular diabetes, they notably susceptible severe complications COVID-19. such, advised stay at home avoid social contact maximum extent possible. This increased patients' vulnerability physical deconditioning, depression, isolation. To address this major gap care, traditional hospital clinic-centered converted all learning contents home-based telerehabilitation There are, however, significant barriers approach that impeded its implementation community. These include variable access use technology (by patients), lack standardization methods tools for evaluation program, inadequate training resources professionals optimally delivering pressing need high-quality studies on these modalities enable successful via teleconferencing technologies. Here, we highlight importance post-COVID world discuss various strategies clinical implementation. Keywords: rehabilitation, telerehabilitation,

Language: Английский

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Do Patients With COVID-19 Benefit from Rehabilitation? Functional Outcomes of the First 100 Patients in a COVID-19 Rehabilitation Unit

Archives of Physical Medicine and Rehabilitation, Journal Year: 2021, Volume and Issue: 102(6), P. 1067 - 1074

Published: Feb. 4, 2021

Language: Английский

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A systematic review on physical function, activities of daily living and health-related quality of life in COVID-19 survivors

Chronic Illness, Journal Year: 2022, Volume and Issue: 19(2), P. 279 - 303

Published: April 11, 2022

To analyze the published studies that investigated physical function, activities of daily living and health-related quality life in COVID-19 survivors.Systematic review.We searched MEDLINE/PubMed, Scopus, SciELO, Cochrane Library for evaluated after from earliest date available to July 2021. Two independent reviewers screened selected studies. The Newcastle Ottawa Scale was used evaluate methodological quality.We included 35 this systematic review. Of included, 28 were cohort, 7 cross-sectional demonstrated survivors had reduced levels living, life. Furthermore, incomplete recovery performance observed 1 6 months post-infection.Physical disability reduction is a common condition post-COVID-19 impairments may persist up months. Researchers clinicians can use these findings understand potential disabilities rehabilitation needs people recovering COVID-19.

Language: Английский

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The Association between COVID-19 Related Anxiety, Stress, Depression, Temporomandibular Disorders, and Headaches from Childhood to Adulthood: A Systematic Review

Brain Sciences, Journal Year: 2023, Volume and Issue: 13(3), P. 481 - 481

Published: March 12, 2023

Objective: The coronavirus belongs to the family of Coronaviridae, which are not branched single-stranded RNA viruses. COVID-19 creates respiratory problems and infections ranging from mild severe. virus features mechanisms that serve delay cellular immune response. host’s response is responsible for pathological process leads tissue destruction. Temporomandibular disorders manifested by painful jaw musculature joint areas, clicks, or creaks when opening closing mouth. All these symptoms can be disabling occur during chewing patient yawns even speaks. pandemic situation has exacerbated anxieties amplified vulnerability individuals. Therefore, this mechanism, how may have increased incidence temporomandibular perceived. purpose review evaluate whether COVID-19-related anxiety caused an increase in dysfunction adults children. Methods: PubMed, Web Science, Lilacs, Scopus were systematically searched, until 30 July 2022, identify studies presenting: connection between with disorders. Results: From 198 papers, 4 included. Literature shown state uncertainty led type disorder, although all agree. Seventy-three identified after viewing four search engines; at end screening phase, only considered met PECO, planned inclusion, exclusion criteria. showed a statistically significant correlation p < 0.05. Conclusions: agreed there association

Language: Английский

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Pulmonary Rehabilitation in COVID-19 patients: A scoping review of current practice and its application during the pandemic

Turkish Journal of Physical Medicine and Rehabilitation, Journal Year: 2020, Volume and Issue: 66(4), P. 480 - 494

Published: Dec. 21, 2020

The novel coronavirus-2019 (COVID-19) pandemic originated in Wuhan, China late December 2019, and rapidly spread to more than 200 countries all around the globe.Currently, there are 19.6 million confirmed cases with 727,435 fatalities. [1][4][5][6] On other hand, children may remain asymptomatic most only detected on laboratory testing.[5] main concern COVID-19 is involvement of lungs respiratory system which result dyspnea, low blood oxygen saturation, failure, thereby, requiring mechanical ventilation, [3,4] mostly those having comorbid conditions such as diabetes mellitus, obesity, ischemic heart disease, cancer, post-surgery, chronic obstructive pulmonary disease (COPD). [3,5]

Language: Английский

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Functional outcome after inpatient rehabilitation in postintensive care unit COVID-19 patients: findings and clinical implications from a real-practice retrospective study

European Journal of Physical and Rehabilitation Medicine, Journal Year: 2021, Volume and Issue: 57(3)

Published: July 1, 2021

BACKGROUND: Coronavirus disease 2019 (COVID-19) pandemic is quickly spreading worldwide, with survivors that suffer functional impairments a consequent key role of rehabilitation in this context. To date, there lack findings on the postacute COVID-19 patients.AIM: Thus, we aimed at describing patient-tailored plan outcome hospitalized patients.DESIGN: Real-practice retrospective study.SETTING: Inpatients Rehabilitation Unit.POPULATION: Postacute patients.METHODS: Medical records patients referred to an Italian Unit from March 10th, 2020 April 30th, were collected. All underwent rehabilitative (30 minutes/set, 2 times/day), improve gas exchanges, reducing dyspnoea, and improving muscle function. At admission (T0) discharge (T1), evaluated as measures: Barthel Index (BI), modified Research Council Dyspnea Scale, 6-Minute Walking Test (6-MWT) Borg Rating Perceived Exertion (RPE) scale. We also assessed: type respiratory supports needed, pulmonary function, coagulation inflammation markers length stay (LOS) Unit.RESULTS: included 41 (25 male 19 female), mean aged 72.15±11.07 years. Their LOS was 31.97±9.06 days, 39 successfully completed treatment deceased. found statistically significant improvement BI (84.87±15.56 vs. 43.37±26.00; P<0.0001), 6-MWT (303.37±112.18 240.0±81.31 meters; P=0.028), RPE scale (12.23±2.51 16.03±2.28; P<0.0001).CONCLUSIONS: These suggest might beneficiate motor treatment. However, further studies are advised better understand long-term sequelae disease.CLINICAL REHABILITATION IMPACT: This study provides evidence inpatients through

Language: Английский

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