Antibiotics,
Journal Year:
2022,
Volume and Issue:
11(11), P. 1483 - 1483
Published: Oct. 26, 2022
Antimicrobial
peptides
(AMPs)
are
constituents
of
the
innate
immune
system
in
every
kind
living
organism.
They
can
act
by
disrupting
microbial
membrane
or
without
affecting
stability.
Interest
these
small
stems
from
fear
antibiotics
and
emergence
microorganisms
resistant
to
antibiotics.
Through
metabolic
disruption,
they
defend
an
organism
against
invading
bacteria,
viruses,
protozoa,
fungi.
High
efficacy
specificity,
low
drug
interaction
toxicity,
thermostability,
solubility
water,
biological
diversity
suggest
their
applications
food,
medicine,
agriculture,
animal
husbandry,
aquaculture.
Nanocarriers
be
used
protect,
deliver,
improve
bioavailability
effectiveness.
cost
production
could
limit
use.
This
review
summarizes
natural
sources,
structures,
modes
action,
food
pharmaceutical
industries.
Any
restrictions
on
AMPs’
large-scale
also
taken
into
consideration.
International Journal of Molecular Sciences,
Journal Year:
2023,
Volume and Issue:
24(10), P. 9031 - 9031
Published: May 20, 2023
Antimicrobial
peptides
(AMPs),
or
host
defence
peptides,
are
short
proteins
in
various
life
forms.
Here
we
discuss
AMPs,
which
may
become
a
promising
substitute
adjuvant
pharmaceutical,
biomedical,
and
cosmeceutical
uses.
Their
pharmacological
potential
has
been
investigated
intensively,
especially
as
antibacterial
antifungal
drugs
antiviral
anticancer
agents.
AMPs
exhibit
many
properties,
some
of
these
have
attracted
the
attention
cosmetic
industry.
being
developed
novel
antibiotics
to
combat
multidrug-resistant
pathogens
treatments
for
diseases,
including
cancer,
inflammatory
disorders,
viral
infections.
In
biomedicine,
wound-healing
agents
because
they
promote
cell
growth
tissue
repair.
The
immunomodulatory
effects
could
be
helpful
treatment
autoimmune
diseases.
industry,
ingredients
skincare
products
due
their
antioxidant
properties
(anti-ageing
effects)
activity,
allows
killing
bacteria
that
contribute
acne
other
skin
conditions.
benefits
make
them
thrilling
area
research,
studies
underway
overcome
obstacles
fully
harness
therapeutic
potential.
This
review
presents
structure,
mechanisms
action,
possible
applications,
production
methods,
market
AMPs.
Gels,
Journal Year:
2023,
Volume and Issue:
9(7), P. 539 - 539
Published: July 3, 2023
Aloe
vera-based
hydrogels
have
emerged
as
promising
platforms
for
the
delivery
of
therapeutic
agents
in
wound
dressings
due
to
their
biocompatibility
and
unique
wound-healing
properties.
The
present
study
provides
a
comprehensive
overview
recent
advances
application
healing.
synthesis
methods,
structural
characteristics,
properties
are
discussed.
Mechanisms
released
from
hydrogels,
including
diffusion,
swelling,
degradation,
also
analyzed.
In
addition,
effects
on
healing,
well
reduction
inflammation,
antimicrobial
activity,
tissue
regeneration,
highlighted.
incorporation
various
agents,
such
anti-inflammatory
ones,
into
is
reviewed
detail.
Furthermore,
challenges
future
prospects
dressing
applications
considered.
This
review
valuable
information
current
status
highlights
potential
improve
healing
outcomes.
Antibiotics,
Journal Year:
2023,
Volume and Issue:
12(9), P. 1434 - 1434
Published: Sept. 11, 2023
Wound
management
represents
a
substantial
clinical
challenge
due
to
the
growing
incidence
of
chronic
skin
wounds
resulting
from
venous
insufficiency,
diabetes,
and
obesity,
along
with
acute
injuries
surgical
wounds.
The
risk
infection,
key
impediment
healing
driver
increased
morbidity
mortality,
is
primary
concern
in
wound
care.
Recently,
antimicrobial
dressings
have
emerged
as
promising
approach
for
bioburden
control
healing.
selection
suitable
dressing
depends
on
various
parameters,
including
cost,
type,
local
microbial
burden
location
condition
wound.
This
review
covers
different
types
dressings,
their
modes
action,
advantages,
drawbacks,
thereby
providing
clinicians
knowledge
optimize
management.
International Journal of Molecular Sciences,
Journal Year:
2023,
Volume and Issue:
24(3), P. 2191 - 2191
Published: Jan. 22, 2023
Natural
hydrogels
are
widely
used
as
biomedical
materials
in
many
areas,
including
drug
delivery,
tissue
scaffolds,
and
particularly
wound
dressings,
where
they
can
act
an
antimicrobial
factor
lowering
the
risk
of
microbial
infections,
which
serious
health
problems,
especially
with
respect
to
healing.
In
this
review
article,
a
number
promising
strategies
development
biocidal
properties,
those
originating
from
natural
polymers,
briefly
summarized
concisely
discussed.
Common
design
fabricate
intrinsic
or
stimuli-triggered
antibacterial
activity
exemplified,
mechanisms
lying
behind
these
properties
also
Finally,
practical
applications
considered
while
discussing
current
challenges
perspectives.
Antibiotics,
Journal Year:
2024,
Volume and Issue:
13(3), P. 202 - 202
Published: Feb. 21, 2024
Antimicrobial
peptides
(AMPs)
are
usually
made
up
of
fewer
than
100
amino
acid
residues.
They
found
in
many
living
organisms
and
an
important
factor
those
organisms’
innate
immune
systems.
AMPs
can
be
extracted
from
various
sources,
including
bacteria,
plants,
animals,
even
humans.
cationic
with
amphiphilic
structure,
which
allows
them
to
easily
bind
interact
the
cellular
membranes
viruses,
fungi,
other
pathogens.
act
against
both
Gram-negative
Gram-positive
pathogens
have
modes
action
them.
Some
attack
pathogens’
membranes,
while
others
target
their
intracellular
organelles,
as
well
nucleic
acids,
proteins,
metabolic
pathways.
A
crucial
area
AMP
use
is
related
ability
help
emerging
antibiotic
resistance:
some
active
resistant
strains
susceptible
peptide
engineering.
This
review
considers
three
key
sources—plants,
humans—as
sequences.
Microorganisms,
Journal Year:
2024,
Volume and Issue:
12(7), P. 1259 - 1259
Published: June 21, 2024
Antimicrobial
resistance
(AMR)
poses
a
serious
global
health
concern,
resulting
in
significant
number
of
deaths
annually
due
to
infections
that
are
resistant
treatment.
Amidst
this
crisis,
antimicrobial
peptides
(AMPs)
have
emerged
as
promising
alternatives
conventional
antibiotics
(ATBs).
These
cationic
peptides,
naturally
produced
by
all
kingdoms
life,
play
crucial
role
the
innate
immune
system
multicellular
organisms
and
bacterial
interspecies
competition
exhibiting
broad-spectrum
activity
against
bacteria,
fungi,
viruses,
parasites.
AMPs
target
pathogens
through
multiple
mechanisms,
most
importantly
disrupting
their
membranes,
leading
cell
lysis.
However,
host
has
slow
co-evolutionary
process
between
microorganisms
hosts.
Alarmingly,
development
last-resort
treatment
MDR
infections,
such
colistin,
is
attributed
misuse
peptide
high
rate
horizontal
genetic
transfer
corresponding
genes.
AMP-resistant
bacteria
employ
diverse
including
but
not
limited
proteolytic
degradation,
extracellular
trapping
inactivation,
active
efflux,
well
complex
modifications
wall
membrane
structures.
This
review
comprehensively
examines
constitutive
inducible
molecular
mechanisms
supported
experimental
evidence
described
date
pathogens.
We
also
explore
specificity
these
toward
structurally
broaden
enhance
potential
developing
applying
them
therapeutics
for
bacteria.
Additionally,
we
provide
insights
into
significance
AMP
within
context
host-pathogen
interactions.
Sustainability,
Journal Year:
2021,
Volume and Issue:
13(18), P. 10198 - 10198
Published: Sept. 13, 2021
The
exponential
increase
of
global
demand
for
proteins
and
lipids
can
no
longer
be
satisfied
by
classical
sources.
High
amounts
CO2
produced
intensive
livestock
breeding
its
effects
on
the
environment
are
main
factors
that
prevent
use
animals
as
primary
sources
lipids,
calling
new
sustainable
sources,
such
insects.
massive
bioconverter
insects
a
feed
source
has
been
major
topic
in
recent
years,
with
both
economic
scientific
aspects
related
to
rearing
subsequent
processing
optimization.
larvae
Hermetia
illucens
(Diptera:
Stratiomyidae)
(also
known
Black
Soldier
Fly)
used
eco-sustainable
production
high
biological
value.
Lipids
obtained
from
BSF
bioconversion
processes
present
quantities
last
instar
prepupae.
Fats
animal
ingredients,
formulation
several
products
personal
care,
biodiesel
production.
To
enable
insect-derived
it
is
important
understand
how
optimize
their
extraction.
Here,
we
summarize
published
information
composition,
extraction
methods,
possible
applications
lipid
component.
