Unlocking Flavor Potential Using Microbial β-Glucosidases in Food Processing DOI Creative Commons
Mariam Muradova,

Alena Proskura,

Francis Canon

et al.

Foods, Journal Year: 2023, Volume and Issue: 12(24), P. 4484 - 4484

Published: Dec. 14, 2023

Aroma is among of the most important criteria that indicate quality food and beverage products. compounds can be found as free molecules or glycosides. Notably, a significant portion aroma precursors accumulates in numerous products nonvolatile flavorless glycoconjugates, termed glycosidic precursors. When subjected to enzymatic hydrolysis, these seemingly inert, glycosides undergo transformation into fragrant volatiles generate odor-active during processing. In this context, microbial β-glucosidases play pivotal role enhancing compromising development flavors derived from bacteria yeast utilized modulate concentration particular taste compounds, such bitterness, which decreased through hydrolysis by glycosidases. Furthermore, oral microbiota influence flavor perception releasing volatile enhance alter review, considering present diverse products, we underscore significance glycosidases with various origins. Subsequently, delve emerging insights regarding release within human cavity due activity

Language: Английский

Oral microbiota in human health and disease: A perspective DOI Creative Commons
Luigì Santacroce, Pier Carmine Passarelli, Domenico Azzolino

et al.

Experimental Biology and Medicine, Journal Year: 2023, Volume and Issue: 248(15), P. 1288 - 1301

Published: Aug. 1, 2023

The evolution of medical knowledge about oral microbiota has increased awareness its important role for the entire human body health. A wide range microbial species colonizing cavity interact both with each other and their host through complex pathways. Usually, these interactions lead to a harmonious coexistence (i.e. eubiosis). However, several factors – including diet, poor hygiene, tobacco smoking, certain medications, among others can disrupt this weak homeostatic balance dysbiosis) potential implications on development caries periodontal disease) systemic This article is thus aimed at providing an overview importance in mediating physiological pathological conditions affecting In context, strategies based hygiene diet as well probiotics supplementation are discussed.

Language: Английский

Citations

62
Oral microbiota and oral squamous cell carcinoma: a review of their relation and carcinogenic mechanisms DOI Creative Commons
Bayu Indra Sukmana, Raed Obaid Saleh,

Maryam Abdulrahman Najim

et al.

Frontiers in Oncology, Journal Year: 2024, Volume and Issue: 14

Published: Feb. 5, 2024

Oral Squamous Cell Carcinoma (OSCC) is the most common type of head and neck cancer worldwide. Emerging research suggests a strong association between OSCC oral microbiota, diverse community bacteria, fungi, viruses, archaea. Pathogenic in particular Porphyromonas gingivalis Fusobacterium nucleatum , have been closely linked to OSCC. Moreover, certain such as Candida albicans like human papillomavirus, also implicated Despite these findings, precise mechanisms through which microbiota influences development remain unclear necessitate further research. This paper provides comprehensive overview its relationship with discusses potential carcinogenic pathways that may activate or modulate are discussed.

Language: Английский

Citations

18
The Complicated Relationship of Short-Chain Fatty Acids and Oral Microbiome: A Narrative Review DOI Creative Commons
Georgy Leonov, Y. Varaeva, E.N. Livantsova

et al.

Biomedicines, Journal Year: 2023, Volume and Issue: 11(10), P. 2749 - 2749

Published: Oct. 11, 2023

The human oral microbiome has emerged as a focal point of research due to its profound implications for health. involvement short-chain fatty acids in composition, health, and chronic inflammation is gaining increasing attention. In this narrative review, the results early vitro, vivo, pilot clinical studies projects are presented order define boundaries new complicated issue. According results, current data disputable ambiguous. When investigating role SCFAs health disease, it crucial distinguish between their local GI effects systemic influences. Locally, part normal microbiota metabolism, but increased formation usually attribute dysbiosis; excess participate development diseases biota gut colonization dysbiosis. On other hand, number have established positive impact on whole, including reduction inflammation, improvement metabolic processes, decrease some types cancer incidence. Thus, complex sophisticated approach with consideration origin localization SCFA function assessment demanded. Therefore, more research, especially needed investigate relationship disease potential prevention treatment.

Language: Английский

Citations

27
Antimicrobial photodynamic therapy against oral biofilm: influencing factors, mechanisms, and combined actions with other strategies DOI Creative Commons
Yijun Li,

Guanwen Sun,

Jingchan Xie

et al.

Frontiers in Microbiology, Journal Year: 2023, Volume and Issue: 14

Published: June 9, 2023

Oral biofilms are a prominent cause of wide variety oral infectious diseases which still considered as growing public health problems worldwide. harbor specific virulence factors that would aggravate the process and present resistance to some traditional therapies. Antimicrobial photodynamic therapy (aPDT) has been proposed potential approach eliminate via in situ -generated reactive oxygen species. Although numerous types research have investigated effectiveness aPDT, few review articles listed antimicrobial mechanisms aPDT on new methods improve efficiency aPDT. The aims summarize biofilms, progress various biofilm elimination, mechanism mediated by combinatorial approaches with other agents.

Language: Английский

Citations

24
Therapeutic Strategies and Genetic Implications for Periodontal Disease Management: A Systematic Review DOI Open Access
Alessandra Laforgia, Alessio Danilo Inchingolo, Fabio Piras

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(13), P. 7217 - 7217

Published: June 29, 2024

The objective of this review is to identify the microbiological alterations caused by various therapy modalities critically analyzing current findings. We limited our search English-language papers published between 1 January 2004 and 7 May 2024 in PubMed, Scopus, Web Science that were relevant topic. In approach, Boolean keywords "microbio*" AND "periodontitis" used. A total 5152 obtained from databases (2205), PubMed (1793), Scopus (1154). This resulted 3266 articles after eliminating duplicates (1886), 1411 entries eliminated their titles abstracts examined. qualitative analysis 22 final included study. Research on periodontal disease shows periodontitis alters oral microbiome increases antibiotic resistance. Treatments like scaling root planing (SRP), especially when combined with minocycline, improve clinical outcomes reducing harmful bacteria. Comprehensive mechanical debridement antibiotics, probiotics, EMD bone grafts, other adjunctive therapies enhances health. Personalized treatment strategies advanced microbial analyses are crucial for effective management resistance control.

Language: Английский

Citations

16
The Antimicrobial Potential of the Hop (Humulus lupulus L.) Extract against Staphylococcus aureus and Oral Streptococci DOI Creative Commons
А. С. Халиуллина,

Alyona Kolesnikova,

Leysan Airatovna Khairullina

et al.

Pharmaceuticals, Journal Year: 2024, Volume and Issue: 17(2), P. 162 - 162

Published: Jan. 27, 2024

Plant extracts are in the focus of pharmaceutical industry as potential antimicrobials for oral care due to their high antimicrobial activity coupled with low production costs and safety eukaryotic cells. Here, we show that extract from Hop (Humulus lupulus L.) exhibits against Staphylococcus aureus Streptococci both planktonic biofilm-embedded forms. An was prepared by acetone extraction hop infructescences, followed purification solubilization remaining fraction ethanol. The effect on S. (MSSA MRSA) comparable reference antibiotics (amikacin, ciprofloxacin, ceftriaxone) did not depend bacterial resistance methicillin. also demonstrated synergy amikacin six clinical isolates, four isolates three ceftriaxone. On various Streptococci, while demonstrating lower activity, an exhibited a considerable synergistic combination two these antibiotics, decreasing MIC up 512-fold. Moreover, able penetrate mutans biofilms, leading almost complete death within them. thin-layer chromatography LC-MS revealed presence prenylated flavonoids (2′,4′,6′,4-tetrahydroxy-3′-geranylchalcone) acylphloroglucides (cohumulone, colupulone, humulone, lupulone), apparently responsible observed ability increase efficiency antibiotics. Taken together, data suggest H. promising agent use solely antiseptic potentiate conventional antimicrobials.

Language: Английский

Citations

11
Caries Etiology and Preventive Measures DOI Creative Commons
Frederic Meyer, Erik Schulze zur Wiesche, Bennett T. Amaechi

et al.

European Journal of Dentistry, Journal Year: 2024, Volume and Issue: 18(03), P. 766 - 776

Published: March 31, 2024

Abstract Caries is a widespread disease in both children and adults. caused by the conversion of fermentable carbohydrates plaque bacteria into acids on tooth surface. Thus, it important to focus sugar reduction control. For efficient removal/control, state-of-the-art toothpastes contain various active ingredients such as antimicrobial agents (e.g., chlorhexidine, stannous salts, zinc salts), abrasives calcium carbonate, phosphates, hydrated silica), surfactants sodium lauryl sulfate methyl cocoyl taurate), natural compounds polyphenols xylitol). Agents with pH-buffering calcium-releasing properties carbonate phosphates) biomimetic actives hydroxyapatite) reverse effects acids. Additionally, modern toothbrushes (i.e., electric toothbrushes) well dental floss interdental brushes significantly help remove from surfaces including interproximal surfaces. In conclusion, concepts caries prevention should not only remineralization alone but also control all key factors involved development.

Language: Английский

Citations

11
Mediterranean diet: a potential player in the link between oral microbiome and oral diseases DOI Creative Commons

Giuseppina Augimeri,

Giovanna Caparello, Ippolito Caputo

et al.

Journal of Oral Microbiology, Journal Year: 2024, Volume and Issue: 16(1)

Published: March 19, 2024

Background The oral microbiome is a complex and dynamic assemblage of microorganisms that colonize different sites the cavity maintaining both systemic health. Therefore, when its composition altered, diseases occur. Among inflammatory pathologies, periodontal affect tissues surrounding teeth, representing main cause tooth loss one most important threats to Lifestyle eating habits influence human microbiota development progression diseases. In this context, Mediterranean Diet (MD) model, comprising healthy dietary choices lifestyle, linked prevention several metabolic chronic-degenerative pathological processes, including Indeed, MD plant-based diet, enriched anti-inflammatory antioxidant nutrients, which may induce beneficial effects against dental caries

Language: Английский

Citations

10
The oral microbiome and oral and upper gastrointestinal diseases DOI Creative Commons
S Liu, Shidong Wang, Nan Zhang

et al.

Journal of Oral Microbiology, Journal Year: 2024, Volume and Issue: 16(1)

Published: June 3, 2024

Background Microbiomes are essential components of the human body, and their populations substantial. Under normal circumstances, microbiomes coexist harmoniously with but disturbances in this equilibrium can lead to various diseases. The oral microbiome is involved occurrence development many gastrointestinal This review focuses on relationship between upper diseases, therapeutic strategies aiming provide valuable insights for clinical prevention treatment.

Language: Английский

Citations

9
The Effect of Oral Microbiota on the Severity and Prognosis of Stroke DOI Open Access
F. A. Yusupov, A. A. Yuldashev,

A.A. Yusupov

et al.

Bulletin of Science and Practice, Journal Year: 2025, Volume and Issue: 11(1), P. 124 - 145

Published: Jan. 15, 2025

The microbiome of the oral cavity plays an important role in development and progression various somatic diseases, including stroke. Studies show that bacteria living can enter bloodstream contribute to inflammatory processes, which increases risk cardiovascular disease It was found 79% studied stroke-related blood clots, DNA commonly cavity, such as streptococci Viridans species, found. Periodontal pathogenic microorganisms cause chronic inflammation atherosclerosis, is one main factors for Dysbiosis also associated with increase level proinflammatory cytokines, worsen condition vessels likelihood thrombosis. Thus, maintaining health timely treatment dental diseases have a significant impact on reducing Understanding relationship between state system opens up new horizons preventive measures therapeutic approaches patients at high

Language: Английский

Citations

1