Food Bioengineering,
Journal Year:
2024,
Volume and Issue:
3(1), P. 41 - 64
Published: March 1, 2024
Abstract
Probiotics
have
become
increasingly
popular
over
the
past
two
decades
due
to
continuously
expanding
scientific
evidence
indicating
their
beneficial
effects
on
human
health.
Therefore,
they
been
applied
in
food
industry
produce
functional
food,
which
plays
a
significant
role
health
and
reduces
disease
risk.
However,
maintaining
viability
of
probiotics
targeting
successful
delivery
gastrointestinal
tract
remain
challenging
tasks
applications.
Specifically,
this
paper
reviews
potentially
properties
probiotics,
highlighting
use
challenges
application
associated
benefits.
Of
foremost
importance,
also
explores
potential
underlying
molecular
mechanisms
enhanced
effect
epithelial
cells,
including
discussion
various
surface
adhesion‐related
proteins
probiotic
cell
that
facilitate
colonization.
Microorganisms,
Journal Year:
2024,
Volume and Issue:
12(1), P. 194 - 194
Published: Jan. 18, 2024
Probiotics
are
known
to
promote
human
health
either
precautionary
in
healthy
individuals
or
therapeutically
patients
suffering
from
certain
ailments.
Although
this
knowledge
was
empirical
past
tomes,
modern
science
has
already
verified
it
and
expanded
new
limits.
These
microorganisms
can
be
found
nature
various
foods
such
as
dairy
products
supplements
formulated
for
clinical
preventive
use.
The
current
review
examines
the
different
mechanisms
of
action
probiotic
strains
how
they
interact
with
organism
host.
Emphasis
is
put
on
therapeutic
use
these
beneficial
conditions
gastrointestinal
tract.
Diseases
tract
particularly
any
malfunction
inflammation
intestines
seriously
compromise
whole
organism.
interaction
between
host’s
microbiota
alleviate
signs
symptoms
while
some
cases,
due
course,
intervene
underlying
pathology.
Various
safety
issues
probiotics
also
discussed.
Scientific Reports,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: May 21, 2024
Abstract
IBD
is
a
disorder
which
could
be
caused
by
oxidative
stress.
This
investigation
aims
to
determine
if
probiotics
and
postbiotics
can
control
stress
inflammation
compare
the
effectiveness
of
these
two
probiotic
postbiotic
mixtures
substances.
88
strains
Lactobacillus
Bifidobacterium
were
tested
for
antioxidant
activity.
Male
wild-type
C57BL/6
mice
divided
into
four
experimental
groups,
namely
high
fat
diet
(HFD)
+
PBS,
HFD
DSS,
DSS
10
9
cfu/ml
probiotics,
postbiotics.
The
phenotypical
indices
pathological
scores
assessed.
expression
genes
related
NF-kB
Nrf2
signaling
pathways
enzymes
associated
with
oxidant/anti-oxidant
activities,
proinflammatory/inflammatory
cytokines
In
contrast
groups
exposed
treated
mixture
alongside
displayed
alleviation
DSS-induced
adverse
effects
on
characteristics,
as
well
molecular
such
genes,
greater
emphasis
component.
accordance
findings
present
investigation,
it
inferred
that
even
in
using
high-fat
dietary
regimen
an
inducer
stress,
emergence
effectively
addressed
through
utilization
and,
more
specifically,
Frontiers in Microbiology,
Journal Year:
2024,
Volume and Issue:
14
Published: Jan. 9, 2024
Object
To
investigate
the
pathogenesis
of
diarrhea
with
kidney-yang
deficiency
syndrome
by
examining
characteristic
changes
in
intestinal
microorganisms,
enzyme
activities,
oxidative
stress,
and
metabolism
indices.
Methods
Twenty
mice
were
randomly
equally
divided
into
control
group
(NC)
model
(NM).
Mice
NM
received
adenine
suspension
at
a
dosage
50
mg/(kg⋅day)
gavage,
0.4
mL/time,
once
day
for
14
days,
Folium
sennae
decoction
10
g/(kg⋅day)
7
starting
on
8th
day.
NC
administered
an
equivalent
amount
sterile
water
gavage
twice
from
After
modeling,
assessments
encompassed
microbial
culture,
organ
index
calculation,
activity
detection,
malondialdehyde
(MDA)
content
determination,
superoxide
dismutase
(SOD)
activity,
blood
biochemical
tests,
observation
kidney
tissue
pathological
changes.
Results
The
results
showed
that
group,
reduction
number
Lactobacillus
Bifidobacteria
was
noted,
accompanied
increase
bacteria
E.
coli
.
Xylanase
contents
mucosa,
protease
mucosa
diminished.
Conversely,
activities
amylase,
sucrase,
lactase
increased
mucosa.
Additionally,
there
elevation
level
MDA.
Renal
tubular
dilatation
inflammatory
cell
infiltration
observed
renal
interstitium.
Conclusion
These
dysfunctions
microorganisms
suggest
potential
involvement
syndrome.
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(1), P. 575 - 575
Published: Jan. 1, 2024
Inflammatory
bowel
disease
(IBD),
a
chronic
condition
that
causes
persistent
inflammation
in
the
digestive
system,
is
closely
associated
with
intestinal
microbiome.
Here,
we
evaluated
effects
of
Lactiplantibacillus
plantarum
HY7718
(HY7718)
on
IBD
symptoms
mice
dextran
sulfate
sodium
(DSS)-induced
colitis.
Oral
administration
led
to
significant
improvement
activity
index
score
and
histological
index,
as
well
preventing
weight
loss,
model
mice.
upregulated
expression
tight
junction
(TJ)-related
genes
downregulated
encoding
pro-inflammatory
cytokines
involved
TLR/MyD88/NF-κB
signaling
pathway.
Additionally,
reduced
blood
levels
cytokines,
reversing
DSS-induced
changes
composition
also
increased
percentage
beneficial
bacteria
(Lactiplantibacillus
Bifidobacterium),
which
correlated
positively
TJ-related
genes.
Finally,
decreased
population
pathogens
such
Escherichia,
symptoms.
The
data
suggest
improves
integrity
colitis
by
regulating
TJ
proteins
inflammatory
microflora.
Thus,
L.
may
be
suitable
functional
supplement
gut
health.
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(15), P. 8451 - 8451
Published: Aug. 2, 2024
Recent
research
indicates
that
the
microbiome
has
a
significant
impact
on
progression
of
inflammatory
bowel
disease
(IBD)
and
creating
therapies
change
its
composition
could
positively
outcomes
IBD
treatment.
This
review
summarizes
results
extensive
studies
examined
patients
undergoing
several
therapies,
including
anti-TNF
medication,
vedolizumab,
ustekinumab,
probiotics,
fecal
microbiota
transplantation
(FMT),
alterations
in
their
gut
microbiota's
function.
The
objective
was
to
investigate
variety
effectiveness
microbial
species
order
discover
new
biomarkers
or
therapeutic
targets
improve
outcome
treatment
for
these
patients.
aimed
offer
useful
insights
into
personalized
medicine
techniques
managing
IBD.
Beneficial
bacteria
such
as
Faecalibacterium
prausnitzii
Roseburia
have
been
consistently
linked
favorable
clinical
outcomes,
whereas
pathogenic
Escherichia
coli
Clostridioides
difficile
are
associated
with
worsening
conditions.
Although
many
role
IBD,
there
is
still
need
more
targeted
connection
between
specific
communities
outcomes.
study
sought
address
this
gap
by
exploring
intricate
relationship
medications.
Frontiers in Veterinary Science,
Journal Year:
2024,
Volume and Issue:
11
Published: Aug. 7, 2024
Oxidative
damage
resulting
from
weaning
stress
significantly
impacts
the
growth
performance
and
health
status
of
piglets.
Taurine,
a
dietary
antioxidant
with
diverse
functions,
was
investigated
in
this
study
for
its
protective
role
against
stress-induced
oxidative
underlying
mechanism.
Forty
28-day-old
male
castrated
weaned
piglets
were
randomly
assigned
to
four
groups.
The
control
group
received
basal
diet,
while
experimental
groups
fed
diet
supplemented
0.1,
0.2%,
or
0.3%
taurine
over
28-day
period.
Frontiers in Microbiology,
Journal Year:
2025,
Volume and Issue:
16
Published: Feb. 5, 2025
This
experiment
was
conducted
to
investigate
the
effects
of
adding
Lactiplantibacillus
plantarum
a
low-protein
diet
on
growth
performance,
ability
immune
status,
and
intestinal
microbiota
0–21-day-old
layer
chickens.
A
total
180
one-day-old
healthy
Hy-line
brown
laying
chicks
were
randomly
divided
into
three
groups
with
replicates
each
20
chicks.
The
control
group
fed
basal
containing
19%
protein,
(LP)
17%
probiotic
(LPL)
protein
supplemented
L.
(1.0
×
10
9
CFU/kg).
antioxidant
capacity,
gut
chickens
detected.
We
found
that
supplementation
increased
activities
superoxide
dismutase
(SOD)
glutathione
peroxidase
(GSH-Px),
capacity
(T-AOC),
levels
immunoglobulin
(Ig)
A,
IgG,
interleukin-10
(IL-10)
in
serum
+1.0
CFU/kg
compared
(control).
Furthermore,
liver
index,
GSH-Px
T-AOC
activity
serum,
changed
microflora
structure,
diversity,
polyketose
unit
bioanabolic
metabolism
(LP).
In
conclusion,
could
compensate
for
adverse
diets
chicks,
combination
is
feasible
way
reduce
diet.
