Biomedicine & Pharmacotherapy,
Journal Year:
2021,
Volume and Issue:
141, P. 111872 - 111872
Published: July 7, 2021
Ferroptosis
is
a
type
of
regulated
cell
death
driven
by
iron
dependent
accumulation
cellular
reactive
oxygen
species
(ROS)
when
glutathione
(GSH)-dependent
lipid
peroxidation
repair
systems
are
compromised.
Nuclear
receptor
co-activator
4
(NCOA4)-mediated
selective
autophagy
ferritin,
termed
ferritinophagy,
involves
the
regulation
ferroptosis.
Emerging
evidence
has
revealed
that
ferritinophagy
and
ferroptosis
exert
significant
role
in
occurrence
development
cardiovascular
disease.
In
present
review,
we
aimed
to
brief
overview
focusing
on
underlying
mechanism
regulations
involved.
We
summarize
discuss
relevant
research
progress
diseases
accompanied
with
potential
applications
modulators
treatment
ferroptosis-associated
diseases.
Chemical Reviews,
Journal Year:
2023,
Volume and Issue:
123(13), P. 8530 - 8574
Published: June 21, 2023
Anionic
species
are
omnipresent
and
involved
in
many
important
biological
processes.
A
large
number
of
artificial
anion
receptors
has
therefore
been
developed.
Some
these
capable
mediating
transmembrane
transport.
However,
where
transport
proteins
can
respond
to
stimuli
their
surroundings,
creation
synthetic
with
stimuli-responsive
functions
poses
a
major
challenge.
Herein,
we
give
full
overview
the
stimulus-controlled
that
have
developed
thus
far,
including
application
membrane
In
addition
potential
operation
as
carriers,
use
recognition
motifs
forming
responsive
membrane-spanning
channels
is
discussed.
With
this
review
article,
intend
increase
interest
among
scientists
working
on
host–guest
complexes
dynamic
functional
systems
order
stimulate
further
developments.
Chemical Society Reviews,
Journal Year:
2024,
Volume and Issue:
53(5), P. 2643 - 2692
Published: Jan. 1, 2024
This
review
discusses
the
structures
and
engineering
strategies
of
nanocatalysts,
highlighting
their
underlying
mechanisms
applications
in
cancer
immunotherapy.
Nano TransMed,
Journal Year:
2024,
Volume and Issue:
3, P. 100032 - 100032
Published: Jan. 29, 2024
Nanozymes
exhibit
immense
potential
and
promising
prospects
in
the
realm
of
diagnostic
imaging
tumor
therapy,
owing
to
their
inherent
physicochemical
properties
enzymatic
activities.
With
further
development
application
nanotechnology,
nanozymes
are
expected
become
an
important
tool
field
medicine,
providing
new
solutions
for
disease
diagnosis
treatment.
This
review
provides
overview
recent
studies
over
past
five
years
on
capable
responding
microenvironment
(TME)
multimodal
imaging,
with
a
focus
hypoxia,
acid
pH,
excess
GSH
ROS.
In
addition,
we
present
current
status
several
common
related
contrast
agents,
such
as
MRI/CT,
MRI/PET,
MRI/SPECT,
PET/CT.
Moreover,
some
thoughts
challenges,
future
development,
clinical
translation
microenvironment-responsive
shared.
aims
provide
up-to-date
theranostic
nanomedicine
reference
those
who
fields,
promote
progress
this
interdisciplinary
subject,
accelerate
translation.
Biomedicine & Pharmacotherapy,
Journal Year:
2021,
Volume and Issue:
141, P. 111872 - 111872
Published: July 7, 2021
Ferroptosis
is
a
type
of
regulated
cell
death
driven
by
iron
dependent
accumulation
cellular
reactive
oxygen
species
(ROS)
when
glutathione
(GSH)-dependent
lipid
peroxidation
repair
systems
are
compromised.
Nuclear
receptor
co-activator
4
(NCOA4)-mediated
selective
autophagy
ferritin,
termed
ferritinophagy,
involves
the
regulation
ferroptosis.
Emerging
evidence
has
revealed
that
ferritinophagy
and
ferroptosis
exert
significant
role
in
occurrence
development
cardiovascular
disease.
In
present
review,
we
aimed
to
brief
overview
focusing
on
underlying
mechanism
regulations
involved.
We
summarize
discuss
relevant
research
progress
diseases
accompanied
with
potential
applications
modulators
treatment
ferroptosis-associated
diseases.