Journal of Materials Science, Journal Year: 2024, Volume and Issue: 59(15), P. 6169 - 6205
Published: March 24, 2024
Language: Английский
Biomolecules, Journal Year: 2021, Volume and Issue: 12(1), P. 31 - 31
Published: Dec. 25, 2021
Nanotechnology is a fast-expanding and multidisciplinary field with many applications in science technology [...]
Language: Английский
Citations
255
Green Chemistry Letters and Reviews, Journal Year: 2022, Volume and Issue: 15(1), P. 187 - 215
Published: Jan. 2, 2022
Copper and oxide nanoparticles have garnered a lot of attention among the metal nanoparticles, especially because their many characteristics applications in disciplines, notably nanomedicine biomedical sciences. We covered all conceivable green production techniques copper/copper this review. This manuscript also diagrammatically depicts exact mechanism biosynthetic routes. look at antibacterial, antifungal, antiviral, anticancer properties biosynthesized as well effects on plant growth, nutrition, defense mechanism.
Language: Английский
Citations
151
Bioinorganic Chemistry and Applications, Journal Year: 2022, Volume and Issue: 2022(1)
Published: Jan. 1, 2022
Orodental problems have long been managed using herbal medicine. The development of nanoparticle formulations with medicine has now become a breakthrough in dentistry because the synthesis biogenic metal nanoparticles (MNPs) plant extracts can address drawbacks treatments. Green production MNPs such as Ag, Au, and Fe enhanced by proven to be beneficial managing numerous orodental disorders, even outperforming traditional materials. Nanostructures are utilized dental advances diagnostics. Oral disease prevention medicines, prostheses, tooth implantation all employ nanoparticles. Nanomaterials also deliver oral fluid or pharmaceuticals, treating cancers providing high level healthcare. These found toothpaste, mouthwash, other care products. However, there is lack understanding about safety nanomaterials, necessitating additional study. Many problems, including medication resistance, might addressed produced green synthesis. This study reviews applied recent studies (2010–2021).
Language: Английский
Citations
124
Molecules, Journal Year: 2023, Volume and Issue: 28(1), P. 463 - 463
Published: Jan. 3, 2023
The unique biological and physicochemical characteristics of biogenic (green-synthesized) nanomaterials (NMs) have attracted significant interest in different fields, with applications the agrochemical, food, medication delivery, cosmetics, cellular imaging, biomedical industries. To synthesize nanomaterials, green synthesis techniques use microorganisms, plant extracts, or proteins as bio-capping bio-reducing agents their role bio-nanofactories for material at nanoscale size. Green chemistry is environmentally benign, biocompatible, nontoxic, economically effective. By taking into account findings from recent investigations, we shed light on most developments using types microbes plants. Additionally, cover green-synthesized food textile industries, water treatment, applications. Furthermore, discuss future perspectives to advance production
Language: Английский
Citations
124
Journal of Functional Biomaterials, Journal Year: 2022, Volume and Issue: 13(4), P. 274 - 274
Published: Dec. 5, 2022
In the last few years, progress made in field of nanotechnology has allowed researchers to develop and synthesize nanosized materials with unique physicochemical characteristics, suitable for various biomedical applications. Amongst these nanomaterials, metal oxide nanoparticles (MONPs) have gained increasing interest due their excellent properties, which a great extent differ from bulk counterpart. However, despite such positive advantages, substantial body literature reports on cytotoxic effects, are directly correlated nanoparticles’ therefore, better control over synthetic parameters will not only lead favorable surface characteristics but may also increase biocompatibility consequently lower cytotoxicity. Taking into consideration enormous potential MONPs, present review discuss most recent developments this referring mainly synthesis methods, physical chemical characterization biological including pro-regenerative antitumor potentials as well antibacterial activity. Moreover, section tackle pressing issue toxic effects MONPs tissues/organs cell lines.
Language: Английский
Citations
92
Biomedicine & Pharmacotherapy, Journal Year: 2022, Volume and Issue: 155, P. 113658 - 113658
Published: Sept. 23, 2022
Anti-microbial resistance (AMR) has recently emerged as an area of high interest owing to the rapid surge AMR phenotypes. Metal oxide NPs (MeONPs) have been identified novel phytomedicine and peaked a lot due their potential applications in combating phytopathogens, besides enhancing plant growth yields. Numerous MeONPs (Ti2O, MgO, CuO, Ag2O, SiO2, ZnO, CaO) synthesized tested validate antimicrobial roles without causing toxicity cells. This review discusses application with special emphasis on anti-microbial activities agriculture enlists how cellular caused through reactive oxygen species (ROS) production affects growth, morphology, viability. further highlights two-facet role silver copper including toxicities. Furthermore, factor modulating nanotoxicity immunomodulation for cytokine also discussed. Thus, this article will not only provide researchers bottlenecks but emphasizes comprehensive outline breakthroughs applicability agriculture.
Language: Английский
Citations
83
Nanotechnology Reviews, Journal Year: 2022, Volume and Issue: 11(1), P. 1322 - 1331
Published: Jan. 1, 2022
Abstract In the present study, pumpkin seed extract was used to synthesize copper oxide nanoparticles (CuO NPs) along with evaluating its anticancer activity using different molecular biology tools in human colorectal cancer cell line (HCT-116). Morphological and structural properties of biogenically synthesized CuO NPs were characterized by UV-visible spectrophotometry (UV-vis), energy-dispersive X-ray spectroscopy (EDS), scanning electron microscopy (SEM), transmission (TEM). For estimating efficacy, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide cytotoxicity, morphological alteration, reactive oxygen species (ROS) formation, alterations mitochondrial membrane potential (MMP) determined. SEM TEM data revealed formation spherical possessing an average size 20 nm. The showed 50% inhibitory concentration (IC 50 ) at 25 µg/mL against HCT-116 line. treatment IC significant shrinking, detachment, blebbing, shape distortion cells. Similarly, dose significantly early apoptosis cells compared late apoptosis. also a dose-dependent increase decrease ROS MMP, respectively. results obtained through various assays indicated efficacy NPs. Thus, further studies are recommended validate our ex vivo models.
Language: Английский
Citations
82
Biomolecules, Journal Year: 2023, Volume and Issue: 13(2), P. 194 - 194
Published: Jan. 18, 2023
Apoptosis is the elimination of functionally non-essential, neoplastic, and infected cells via mitochondrial pathway or death receptor pathway. The process apoptosis highly regulated through membrane channels apoptogenic proteins. maintains cellular balance within human body cell cycle progression. Loss control prolongs cancer survival allows accumulation mutations that can promote angiogenesis, proliferation, disrupt differentiation, increase invasiveness during tumor apoptotic has been extensively studied as a potential drug target in treatment. However, off-target activities drugs negative implications have matter concern over years. Phytochemicals (PCs) for their efficacy various lines individually synergistically. development nanoparticles (NPs) green synthesis added new dimension to advancement plant-based nanomaterials effective This review provides detailed insight into fundamental molecular pathways programmed highlights role PCs along with existing NPs treating by targeting its (PCD) network.
Language: Английский
Citations
72
Inorganic Chemistry Communications, Journal Year: 2023, Volume and Issue: 155, P. 111088 - 111088
Published: July 19, 2023
Language: Английский
Citations
61
Journal of Nanobiotechnology, Journal Year: 2024, Volume and Issue: 22(1)
Published: Jan. 5, 2024
Abstract Periodontitis, one of the most prevalent dental diseases, causes loss bone and gum tissue that hold teeth in place. Several bacteria, commonly present clinically healthy oral cavities, may induce perpetuate periodontitis when their concentration rises gingival sulcus. Antibacterial effect against various Gram-negative Gram-positive including pathogenic drug-resistant ones, has been shown for several distinct transient metal oxide NPs. Therefore, NPs be used biomedicine to treat periodontal problems nanotechnology inhibit development microorganisms. Instead using harmful chemicals or energy-intensive machinery, biosynthesis nanoparticles (NPs) suggested. To produce NPs, ideal technique is “Green” synthesis because its low toxicity safety human health environment. Gold (AuNPs) appear less toxic mammalian cells than other nanometals antibacterial activity not dependent on reactive oxygen species (ROS). AgNPs also possess chemical stability, catalytic activity, superior electrical thermal conductivity, name a few advantageous characteristics. It was observed zinc (ZnO) copper (Cu) exhibited discernible inhibitory effects gram-positive gram-negative bacterial strains, respectively. ZnO demonstrated bactericidal microorganisms responsible periodontitis. Medications containing magnetic are highly effective multidrug-resistant fungal infections. The titanium dioxide (TiO 2 ) implicated elevating salivary peroxidase individuals diagnosed with chronic Furthermore, specific metallic have potential enhance antimicrobial efficacy treatments combined. these as well only some metals oxides synthesized environmentally friendly ways therapeutic benefits Graphical
Language: Английский
Citations
60