Sustainable technologies for the recycling and upcycling of precious metals from e-waste

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 916, P. 170154 - 170154

Published: Jan. 18, 2024

Language: Английский

---

Model for Gold Nanoparticle Synthesis: Effect of pH and Reaction Time

ACS Omega, Journal Year: 2021, Volume and Issue: 6(26), P. 16847 - 16853

Published: June 24, 2021

The synthesis of gold nanoparticles is dependent on both the concentration trisodium citrate dihydrate and time that it interacts with tetrachloroauric acid. A wide range various sizes dispersity can be produced based control variables, such as reaction acid concentration, using a similar approach to Turkevich model. In this model, pH solution decreases slightly throughout (0.005 unit/min) due chemical interactions between Dicarboxy acetone formed during oxidization, resulting in nuclei formation over time. addition, nanoparticle nucleation causes fluctuation sizes. An inverse correlation (coefficient smaller than −0.97) was calculated at different ratios Regression analysis used develop model for prediction size ranging from 18 38 nm

Language: Английский

---

Development of nucleic acid aptamer-based lateral flow assays: A robust platform for cost-effective point-of-care diagnosis

Theranostics, Journal Year: 2021, Volume and Issue: 11(11), P. 5174 - 5196

Published: Jan. 1, 2021

Lateral flow assay (LFA) has made a paradigm shift in the

Language: Английский

---

Functionalization of Metal and Carbon Nanoparticles with Potential in Cancer Theranostics

Molecules, Journal Year: 2021, Volume and Issue: 26(11), P. 3085 - 3085

Published: May 21, 2021

Cancer theranostics is a new concept of medical approach that attempts to combine in unique nanoplatform diagnosis, monitoring and therapy so as provide eradication solid tumor non-invasive fashion. There are many available solutions tackle cancer using theranostic agents such photothermal (PTT) photodynamic (PDT) under the guidance imaging techniques (e.g., magnetic resonance-MRI, photoacoustic-PA or computed tomography-CT imaging). Additionally, there several potential nanoplatforms able diagnosis at once, gold nanoparticles (GNPs), graphene oxide (GO), superparamagnetic iron (SPIONs) carbon nanodots (CDs). Currently, surface functionalization these an extremely useful protocol for effectively tuning their structures, interface features physicochemical properties. This much more reliable amenable fine adjustment, reaching both regulatory requirements function specific field application. Here, we summarize compare most promising metal- carbon-based tools reported candidates precision theranostics. We focused our review on latest developments strategies nanosystems, hybrid nanocomposites consisting combination, discuss main characteristics applications medicine.

Language: Английский

---

Engineering gold nanoparticles for molecular diagnostics and biosensing

Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology, Journal Year: 2022, Volume and Issue: 15(1)

Published: Aug. 5, 2022

Abstract Advances in nanotechnology and medical science have spurred the development of engineered nanomaterials nanoparticles with particular focus on their applications biomedicine. In particular, gold (AuNPs) been great interest, due to exquisite intrinsic properties, such as ease synthesis surface functionalization, tunable size shape, lack acute toxicity favorable optical, electronic, physicochemical features, which possess value for application biodetection diagnostics purposes, including molecular sensing, photoimaging, under form portable simple biosensors (e.g., lateral flow immunoassays that extensively exploited during current COVID‐19 pandemic). We shall discuss main properties AuNPs, conjugation biorecognition moieties, trends sensing detection biomedicine diagnostics. This article is categorized under: Diagnostic Tools > Biosensing Vitro Nanoparticle‐Based Sensing Vivo Nanodiagnostics Imaging

Language: Английский

---

Metal‐based nanomaterials and nanocomposites as promising frontier in cancer chemotherapy

MedComm, Journal Year: 2023, Volume and Issue: 4(2)

Published: April 1, 2023

Abstract Cancer is a disease associated with complex pathology and one of the most prevalent leading reasons for mortality in world. Current chemotherapy has challenges cytotoxicity, selectivity, multidrug resistance, formation stemlike cells. Nanomaterials (NMs) have unique properties that make them useful various diagnostic therapeutic purposes cancer research. NMs can be engineered to target cells early detection deliver drugs directly cells, reducing side effects improving treatment efficacy. Several also used photothermal therapy destroy or enhance immune response by delivering immune‐stimulating molecules modulating tumor microenvironment. are being modified overcome issues, such as toxicity, lack increase drug capacity, bioavailability, wide spectrum therapies. To improve targeted delivery using nano‐carriers, noteworthy research required. metal‐based been studied expectation finding cure treatment. In this review, current development potential plant their on size shape discussed along more effective usage diagnosis

Language: Английский

---

Photothermal Effect of Gold Nanoparticles as a Nanomedicine for Diagnosis and Therapeutics

Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(9), P. 2349 - 2349

Published: Sept. 19, 2023

Gold nanoparticles (AuNPs) have received great attention for various medical applications due to their unique physicochemical properties. AuNPs with tunable optical properties in the visible and near-infrared regions been utilized a variety of such as vitro diagnostics, vivo imaging, therapeutics. Among applications, this review will pay more recent developments diagnostic therapeutic based on photothermal (PT) effect AuNPs. In particular, PT has played an important role utilizing light, photoacoustic photon polymerase chain reaction (PCR), hyperthermia therapy. First, we discuss fundamentals detail understand background For ability efficiently convert absorbed light energy into heat generate enhanced acoustic waves can lead significant enhancements signal intensity. Integration PCR may open new opportunities technological innovation called photonic PCR, where is used enable fast accurate temperature cycling DNA amplification. Additionally, beyond existing thermotherapy AuNPs, be further applied cancer immunotherapy. Controlled damage cells triggers immune response, which useful obtaining better outcomes combination checkpoint inhibitors or vaccines. Therefore, examines nanomedicine among understands basic principles, advantages disadvantages each technology, importance multidisciplinary approach. Based this, it expected that help current status development direction nanoparticle-based disease diagnosis methods treatment methods, hope inspire innovative technologies.

Language: Английский

---

Nano‐Biotechnology and Challenges of Drug Delivery System in Cancer Treatment Pathway: Review Article

Chemistry & Biodiversity, Journal Year: 2023, Volume and Issue: 20(6)

Published: March 1, 2023

Abstract In this review, we discuss Nanotechnology models, which have been developed recently in cancer treatment. manipulates matter at the atomic and molecular scale to create materials with new advanced properties. Nano‐biotechnology consists of branches nanotechnology that applied biology (molecular cellular genetics) biotechnology. allows us put components compounds into cells build using methods like assembly. Cancer is a disease caused by an uncontrolled division abnormal part body. Its therapeutic include chemotherapy, radiation, or surgery, but effects these techniques are not only on tumor tissue may affect healthy tissues. Nano‐Biotech applications regarding drug delivery, treatment, foresight therapy. This review article aims obtain proper mentality current technologies for

Language: Английский

---

Functionalized Metal Nanoparticles in Cancer Therapy

Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(7), P. 1932 - 1932

Published: July 11, 2023

Currently, there are many studies on the application of nanotechnology in therapy. Metallic nanoparticles promising nanomaterials cancer therapy; however, functionalization these with biomolecules has become relevant as their effect cells is considerably increased by photothermal and photodynamic therapies, drug nanocarriers, specificity antibodies, resulting new therapies that more specific against different types cancer. This review describes functionalized palladium, gold, silver platinum treatment cancer, themselves show an anticancer effect. further enhanced when NPs either DNA, RNA, peptides, proteins, or folic acid other molecules. These can penetrate cell accumulate tumor tissue, a cytotoxic through generation ROS, induction apoptosis, cycle arrest, DNA fragmentation, NP-based therapy strategy be used synergistically chemotherapy radiotherapy to achieve effective reduce side effects.

Language: Английский

---

Recent Advances in Synergistic Effect of Nanoparticles and Its Biomedical Application

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(6), P. 3266 - 3266

Published: March 13, 2024

The synergistic impact of nanomaterials is critical for novel intracellular and/or subcellular drug delivery systems minimal toxicity. This synergism results in a fundamental bio/nano interface interaction, which discussed terms nanoparticle translocation, outer wrapping, embedding, and interior cellular attachment. morphology, size, surface area, ligand chemistry charge nanoparticles all play role translocation. In this review, we suggest generalized mechanism to characterize the interface, as discuss interaction between cells, tissues, other biological systems. Novel perceptions are reviewed regarding ability improve hybrid nanocarriers with homogeneous structures enhance multifunctional biomedical applications, such bioimaging, tissue engineering, immunotherapy, phototherapy.

Language: Английский

---