Lemon peel-based fluorescent carbon quantum dots as a functional filler in polyvinyl alcohol-based films for active packaging applications

Industrial Crops and Products, Journal Year: 2024, Volume and Issue: 209, P. 117968 - 117968

Published: Jan. 4, 2024

Language: Английский

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Recent Developments in Citrus aurantium L.: An Overview of Bioactive Compounds, Extraction Techniques, and Technological Applications

Processes, Journal Year: 2025, Volume and Issue: 13(1), P. 120 - 120

Published: Jan. 5, 2025

This review provides an overview of recent developments in Citrus aurantium L. (sour or bitter orange), focusing on its bioactive compounds, innovative extraction techniques, and technological applications. C. is rich compounds such as flavonoids (naringin, hesperidin, kaempferol, quercetin), essential oils (β-pinene, limonene), vitamin C, which represents significant biological activities including antioxidant, antimicrobial, anti-inflammatory, anticancer effects. The discusses traditional methods, solvent hydrodistillation, alongside newer, eco-friendly approaches like ultrasound-assisted extraction, microwave-assisted supercritical fluid natural deep eutectic solvents. It also highlights cutting-edge molecular imprinting polymer-based enable the more efficient enrichment purification specific synephrine. Finally, examines diverse industrial applications these sectors foods, pharmaceuticals, cosmetics, while emphasizing growing need for sustainable technologies.

Language: Английский

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Unveiling the Chemistry of Citrus Peel: Insights into Nutraceutical Potential and Therapeutic Applications

Foods, Journal Year: 2024, Volume and Issue: 13(11), P. 1681 - 1681

Published: May 27, 2024

The recent millennium has witnessed a notable shift in consumer focus towards natural products for addressing lifestyle-related disorders, driven by their safety and cost-effectiveness. Nutraceuticals functional foods play an imperative role meeting nutritional needs offering medicinal benefits. With increased scientific knowledge awareness, the significance of healthy lifestyle, including diet, reducing disease risk is widely acknowledged, facilitating access to diverse safer diet longevity. Plant-based rich phytochemicals are increasingly popular effectively utilized management. Agricultural waste from plant-based being recognized as valuable source nutraceuticals dietary interventions. Citrus peels, known flavonoids, emerging promising health-promoting ingredient. Globally, citrus production yields approximately 15 million tons by-products annually, highlighting substantial potential utilizing phyto-therapeutic nutraceutical applications. peels with concentrations ranging 2.5 5.5 g/100 g dry weight, depending on variety. most abundant flavonoids peel include hesperidin naringin, well essential oils monoterpenes like limonene. extracts exhibit high antioxidant capacity, DPPH radical scavenging activities 70 90%, comparable synthetic antioxidants BHA BHT. Additionally, present have been found properties, which can help reduce oxidative stress 30% cardiovascular 25%. Potent anti-inflammatory effects also demonstrated, inflammatory markers such IL-6 TNF-α up 40% cell culture studies. These findings highlight diet-based therapies.

Language: Английский

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Polyphenol-Rich Extracts and Essential Oil from Egyptian Grapefruit Peel as Potential Antioxidant, Antimicrobial, and Anti-Inflammatory Food Additives

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(7), P. 2776 - 2776

Published: March 26, 2024

Grapefruit (GF) processing generates significant nutrient and economic losses due to the production of 50% by-products, primarily peels. GF peels are a rich sustainable source bioactive compounds (BCs), such as essential oils (EOs) phenolic compounds. Thus, finding value-added solutions based on circular economy is paramount. This research aims assess antioxidant, anti-inflammatory, antimicrobial properties hydroethanolic polyphenol-rich extract from crude (GF-CE), oil (GF-EO), after extraction (GF-PE). The GF-CE GF-PE showed high concentrations naringenin (7.71 48.60 mg/g dry (DE)), narirutin (15.03 28.73 DE), hesperidin (0.67 0.29 mg/mL), respectively. Extracting firstly EOs improved release acids (p-coumaric, ferulic, chlorogenic acid). exhibited stronger free radical scavenging activity mainly in DPPH (IC50 = 75.69 ± 0.81 µg/mL) than GF-EO (1271 0.85 (113.45 µg/mL). demonstrated moderate against Gram-positive bacteria compared reference standard (amoxicillin) strong yeast Candida albicans (inhibition zone 16 mm). major included D-limonene (25%), nootkatone (24%), β-pinene (8%). Both extracts promising activities COX1 COX2 inhibitors with IC50 values 25 0.1 0.28 0.00 µg/mL (compared celecoxib (97.5 0.31 0.01 indomethacin (6.25 0.52 standards), study concludes that valuable BCs bioactivities, offering multi-cascade approach recovering alignment principles open opportunities functional ingredients for food applications.

Language: Английский

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Citrus clementine Peel Essential Oil Ameliorates Potassium Dichromate-Induced Lung Injury: Insights into the PI3K/AKT Pathway

Metabolites, Journal Year: 2024, Volume and Issue: 14(1), P. 68 - 68

Published: Jan. 19, 2024

Acute Lung Injury (ALI) is a life-threatening syndrome that has been identified as potential complication of COVID-19. There critical need to shed light on the underlying mechanistic pathways and explore novel therapeutic strategies. This study aimed examine effects Citrus clementine essential oil (CCEO) in treating potassium dichromate (PDC)-induced ALI. The chemical profile CCEO was created through GC–MS analysis. An vivo rats conducted evaluate effect administrated via two different delivery systems (oral/inhalation) mitigating acute lung injury induced by intranasal instillation PDC. Eight volatile compounds were identified, with monoterpene hydrocarbons accounting for 97.03% constituents, including 88.84% D-limonene. at doses 100 200 mg/kg bw exhibited antioxidant anti-inflammatory properties. These significant properties revealed reduction malondialdehyde (MDA) restoration reduced glutathione (GSH). In addition, inflammation observed decreasing levels cytokines tumor necrosis factor-α growth factor-β (TNF-α TGF-β), along an increase phosphatidylinositide-3-kinase (PI3K) Akt overexpression tissue homogenate, both oral inhalation routes, compared PDC-induced group. results supported histopathological studies immunohistochemical assessment TGF-β tissues. findings plays integral role relieving ALI PDC suggests it promising remedy.

Language: Английский

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Response surface methodology and repeated-batch fermentation strategies for enhancing lipid production from marine oleaginous Candida parapsilosis Y19 using orange peel waste

Microbial Cell Factories, Journal Year: 2025, Volume and Issue: 24(1)

Published: Jan. 10, 2025

Abstract Oleaginous yeasts are considered promising sources for lipid production due to their ability accumulate high levels of lipids under appropriate growth conditions. The current study aimed isolate and identify oleaginous having superior quantities lipids; enhancing using response surface methodology repeated-batch fermentation. Results revealed that, twenty marine were isolated, the most potent producer was Candida parapsilosis Y19 according qualitative screening test Nile-red dye. Orange peels used as substrate where C. produced 1.14 g/l at 23.0% in batch To enhance production, statistical optimization Taguchi design through Response carried out. Total increased 2.46 content 30.7% optimal conditions of: orange peel 75 g/l, peptone 7 yeast extract 5 inoculum size 2% ( v/v ), pH incubation period 6 d. Furthermore, fermentation enhanced total 4.19 folds (4.78 g/l) compared culture (before optimization). Also, 1.7 (39.1%) Fatty acid profile includes unsaturated fatty acids (USFAs) 74.8% saturated (SFAs) 25.1%. Additionally, fermentation, major oleic 45.0%; followed by linoleic 26.0%. In conclusion, is a strain production. both optimizations RSM efficient methods from Y19.

Language: Английский

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Citrus By-Products as a Valuable Source of Biologically Active Compounds with Promising Pharmaceutical, Biological and Biomedical Potential

Pharmaceuticals, Journal Year: 2023, Volume and Issue: 16(8), P. 1081 - 1081

Published: July 29, 2023

Citrus fruits processing results in the generation of huge amounts citrus by-products, mainly peels, pulp, membranes, and seeds. Although they represent a major concern from both economical environmental aspects, it is very important to emphasize that these by-products contain rich source value-added bioactive compounds with wide spectrum applications food, cosmetic, pharmaceutical industries. The primary aim this review highlight great potential isolated phytochemicals extracts individual properties (e.g., antitumor, antimicrobial, antiviral, antidiabetic, antioxidant, other beneficial activities health-promoting abilities) their pharmaceutical, biomedical, biological applications. This on contains following parts: structural chemical characteristics; utilization by-products; bioactivities present waxes carotenoids, essential oils, pectins, phenolic compounds; by-product formulations enhanced biocactivities. A summary recent developments applying for treatment different diseases protection human health also provided, emphasizing innovative methods bioaccessibility enhancements extract/component encapsulation, synthesis biomass-derived nanoparticles, nanocarriers, or biofilm preparation). Based representative phytochemical groups, an evaluation studies past six years (from 2018 2023) reporting specific citrus-based provided. Finally, discusses advanced modern approaches pharmaceutical/biological drug delivery carbon precursors preparation nanoparticles promising antimicrobial activity, production fluorescent application as antitumor agents, cellular imaging). implementing nanotechnology food science biotechnology could bring about new insights into providing solutions medical discoveries.

Language: Английский

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Valorisation of fruit waste for harnessing the bioactive compounds and its therapeutic application

Trends in Food Science & Technology, Journal Year: 2023, Volume and Issue: 144, P. 104302 - 104302

Published: Dec. 17, 2023

Language: Английский

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Industrial and Environmental Applications of Plant-Derived Saponins: An Overview and Future Prospective

Journal of Plant Growth Regulation, Journal Year: 2024, Volume and Issue: 43(9), P. 3012 - 3026

Published: Jan. 5, 2024

Language: Английский

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Egyptian Citrus Essential Oils Recovered from Lemon, Orange, and Mandarin Peels: Phytochemical and Biological Value

Horticulturae, Journal Year: 2024, Volume and Issue: 10(2), P. 180 - 180

Published: Feb. 16, 2024

Citrus peels are an important by-product of citrus processing industries, but a large part is considered waste. There has been increased attention in the last five years on these industrial by-products, especially those containing residual essential oils (EOs). Lemon, orange, and mandarin from Egypt were subjected to hydro-distillation obtain EOs, which analyzed via mass spectrometry (GC/MS) by building Global Natural Products Social Molecular Networking (GNPS-MN) for purpose visually exploring volatile components species. The constructed MN revealed that D-Limonene, α-pinene, β-pinene dominant constituents three Egyptian EOs exhibited promising activities as antioxidants using two tested methods: 1,1-diphenyl-2-picryl-hydrazil (DPPH) nitric oxide (NO) compared with vitamin C. Lemon EO proved excellent antimicrobial activity against Gram-positive negative bacteria. Additionally, showed good yeast Candida albicans. Regarding anti-inflammatory assay, COX-1 COX-2 inhibitors. This study concludes extracted peel waste can be valorized innovative strategy food preservation or may incorporated cosmetics pharmaceutical formulations alignment circular economy principles.

Language: Английский

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