Mediterranean Diet as an Antioxidant: The Impact on Metabolic Health and Overall Wellbeing

Nutrients, Journal Year: 2021, Volume and Issue: 13(6), P. 1951 - 1951

Published: June 6, 2021

It has been established, worldwide, that non-communicable diseases such as obesity, diabetes, metabolic syndrome, and cardiovascular events account for a high percentage of morbidity mortality in contemporary societies. Several modifiable risk factors, sedentary activities, sleep deprivation, smoking, unhealthy dietary habits have contributed to this increase. Healthy nutrition terms adherence the Mediterranean diet (MD), rich fruits, legumes, vegetables, olive oil, herbs, spices, fiber intake may contribute decrease pandemic. The beneficial effects MD can be mainly attributed its numerous components anti-inflammatory antioxidant properties. Moreover, further improvement reproductive health, modify neurodegenerative diseases, protect against depression psychosocial maladjustment. There is also evidence highlighting impact healthy female people on composition gut microbiota future overall health their offspring. therefore important highlight metabolic, reproductive, mental while shaping generations. enhanced by increased physical activity context well-balanced lifestyle.

Language: Английский

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Single and Double Strand Sperm DNA Damage: Different Reproductive Effects on Male Fertility

Genes, Journal Year: 2019, Volume and Issue: 10(2), P. 105 - 105

Published: Jan. 31, 2019

Reproductive diseases have become a growing worldwide problem and male factor plays an important role in the reproductive diagnosis, prognosis design of assisted treatments. Sperm cell holds mission carrying paternal genetic complement to oocyte order contribute euploid zygote with proper DNA integrity. fragmentation had been used for decades as fertility test, however, its usefulness arisen multiple debates, especially around Intracytoplasmic Injection (ICSI) In recent years, it has described that different types sperm breaks (single double strand breaks) cause clinical effects. On one hand, single-strand are present extensively break points all regions genome, related oxidative stress lack pregnancy or increase conception time. other double-strand mainly localized attached nuclear matrix very few points, possibly repair meiosis higher risk miscarriage, low embryo quality implantation failure ICSI cycles. The work also reviews studies may understanding chromatin well treatments prevent damage.

Language: Английский

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Bioactive food compounds, epigenetics and chronic disease prevention: Focus on early-life interventions with polyphenols

Food Research International, Journal Year: 2019, Volume and Issue: 125, P. 108646 - 108646

Published: Aug. 24, 2019

Language: Английский

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Green and white teas as health-promoting foods

Food & Function, Journal Year: 2021, Volume and Issue: 12(9), P. 3799 - 3819

Published: Jan. 1, 2021

Tea is one of the most consumed beverages around world and as such, it constantly object novel research.

Language: Английский

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Plant Extracts as Alternative Additives for Sperm Preservation

Antioxidants, Journal Year: 2021, Volume and Issue: 10(5), P. 772 - 772

Published: May 13, 2021

Sperm preservation is a crucial factor for the success of assisted reproductive technology (ART) in humans, livestock, and wildlife. Irrespective extender storage conditions used, semen handling negatively affect sperm quality. Moreover, oxidative stress, which often arises during storage, significantly reduces function compromises fertilizing ability by inducing damage to proteins, lipids, nucleic acids. Plant extracts have recently emerged as cheap natural source additives preserve enhance storage. The present work provides an update on use these compounds alternative 13 animal species, including humans. A detailed description effects 45 plant belonging 28 families, presented. material extraction method employed, dosage, possible toxic effects, antimicrobial properties are provided.

Language: Английский

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T-2 Toxin Nephrotoxicity: Toxic Effects, Mechanisms, Mitigations, and Future Perspectives

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 27, 2025

T-2 toxin is a highly toxic fungal that threatens humans and animals' health. As major detoxifying metabolic organ, the kidney also target of toxin. This article reviews nephrotoxicity research progress, covering renal structure function damage, mechanisms, detoxification methods to future directions. damages structure, causing dysfunction. The mechanism involves multiple factors including oxidative stress, endoplasmic reticulum mitophagy, inflammatory responses, apoptosis, which are intertwined interdependent. Current strategies mainly involve reducing in feedstuff using antioxidant substances, but both have limits. Future should focus on cells sensitivity toxin, exploring key molecules toxin's nephrotoxicity, injury's impact other organs, better methods. review aims guide underpin toxin-induced prevention treatment.

Language: Английский

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Ameliorating Effects of Natural Antioxidant Compounds on Female Infertility: a Review

Reproductive Sciences, Journal Year: 2020, Volume and Issue: 28(5), P. 1227 - 1256

Published: Sept. 15, 2020

Language: Английский

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Nutritional applications and beneficial health applications of green tea and l‐theanine in some animal species: A review

Journal of Animal Physiology and Animal Nutrition, Journal Year: 2019, Volume and Issue: 104(1), P. 245 - 256

Published: Oct. 8, 2019

Abstract Green tea ( Camellia sinensis ) is a popular herbal plant with abundant health benefits, and thus, it has been used as potent antioxidant for long time. Based on the available literature, diversity availability of multifunctional compounds in green offer its noteworthy potential against many diseases such liver heart diseases, inflammatory conditions different metabolic syndromes. Owing to bioactive constituents including caffeine, amino acids, l ‐theanine, polyphenols/flavonoids carbohydrates among other molecules, pharmacological physiological effects. The effects include anti‐oxidative, anti‐inflammatory, anti‐arthritic, anti‐stress, hypolipidaemic, hypocholesterolaemic, skin/collagen protective, hepatoprotective, anti‐diabetic, anti‐microbial, anti‐infective, anti‐parasitic, anti‐cancerous, inhibition tumorigenesis angiogenesis, anti‐mutagenic, memory bone health‐improving activities. Apart from utilization humans, also played significant role livestock production dairy, piggery, goatry poultry industries. Supplementation animal feeds products line modern concepts organic production. Hence, incorporating or by‐products into diet can enhance value obtained these animals. Herein, an effort made extend knowledge importance useful applications important poultry. This review will be guideline researchers entrepreneurs who want explore supplemented enhancement

Language: Английский

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Hormonal regulation of health-promoting compounds in tea (Camellia sinensis L.)

Plant Physiology and Biochemistry, Journal Year: 2022, Volume and Issue: 185, P. 390 - 400

Published: June 21, 2022

Language: Английский

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The emergence of natural products as potential therapeutics for male infertility

Andrology, Journal Year: 2024, Volume and Issue: 12(6), P. 1191 - 1208

Published: Jan. 8, 2024

Infertility is a major reproductive health problem. Approximately 50% of all documented cases infertility are attributable to male factors, such as poor testicular function and semen quality. The recent significant global decline in sperm counts has serious implications for fertility, but the armamentarium improving quality limited. Natural products have wide range activities source drugs disease prevention treatment. To provide ideas theoretical basis research development therapeutic infertility, this review summarizes natural (mostly monomers) that been shown improve their possible mechanisms action. These primarily via antioxidant, antiapoptotic, anti-inflammatory effects, addition increasing serum testosterone reducing DNA damage spermatozoa cells. Prospects application treatment discussed.

Language: Английский

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