Effects of time-restricted feeding on body weight and metabolism. A systematic review and meta-analysis

Reviews in Endocrine and Metabolic Disorders, Journal Year: 2019, Volume and Issue: 21(1), P. 17 - 33

Published: Dec. 6, 2019

Language: Английский

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Diabetes and Ramadan: Practical guidelines 2021

Diabetes Research and Clinical Practice, Journal Year: 2022, Volume and Issue: 185, P. 109185 - 109185

Published: Jan. 8, 2022

Language: Английский

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Chronic cerebral hypoperfusion: a critical feature in unravelling the etiology of vascular cognitive impairment

Acta Neuropathologica Communications, Journal Year: 2023, Volume and Issue: 11(1)

Published: June 12, 2023

Vascular cognitive impairment (VCI) describes a wide spectrum of deficits related to cerebrovascular diseases. Although the loss blood flow cortical regions critically involved in processes must feature as main driver VCI, underlying mechanisms and interactions with disease remain be fully elucidated. Recent clinical studies cerebral measurements have supported role chronic hypoperfusion (CCH) major vascular pathology manifestations VCI. Here we review pathophysiological well neuropathological changes CCH. Potential interventional strategies for VCI are also reviewed. A deeper understanding how CCH can lead accumulation VCI-associated could potentially pave way early detection development disease-modifying therapies, thus allowing preventive interventions instead symptomatic treatments.

Language: Английский

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Gut Microbiota at the Crossroad of Hepatic Oxidative Stress and MASLD

Antioxidants, Journal Year: 2025, Volume and Issue: 14(1), P. 56 - 56

Published: Jan. 6, 2025

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent chronic condition marked by excessive lipid accumulation in hepatic tissue. This disorder can lead to range of pathological outcomes, including metabolic steatohepatitis (MASH) and cirrhosis. Despite extensive research, the molecular mechanisms driving MASLD initiation progression remain incompletely understood. Oxidative stress peroxidation are pivotal "multiple parallel hit model", contributing cell death tissue damage. Gut microbiota plays substantial role modulating oxidative through multiple pathways: impairing intestinal barrier, which results bacterial translocation inflammation; modifying bile acid structure, impacts signaling cascades involved lipidic metabolism; influencing hepatocytes' ferroptosis, form programmed death; regulating trimethylamine N-oxide (TMAO) activating platelet function, both recently identified as pathogenetic factors MASH progression. Moreover, various exogenous impact gut its involvement MASLD-related stress, such air pollution, physical activity, cigarette smoke, alcohol, dietary patterns. manuscript aims provide state-of-the-art overview focused on intricate interplay between microbiota, peroxidation, pathogenesis, offering insights into potential strategies prevent associated complications.

Language: Английский

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Energy Metabolism and Intermittent Fasting: The Ramadan Perspective

Nutrients, Journal Year: 2019, Volume and Issue: 11(5), P. 1192 - 1192

Published: May 27, 2019

Intermittent fasting (IF) has been gaining popularity as a means of losing weight. The Ramadan fast (RF) is form IF practiced by millions adult Muslims globally for whole lunar month every year. It entails major shift from normal eating patterns to exclusive nocturnal eating. RF state intermittent liver glycogen depletion and repletion. earlier (morning) part the day marked dominance carbohydrate main fuel, but lipid becomes more important towards afternoon time breaking at sunset (iftar) gets closer. practice observing accompanied changes in sleeping activity patterns, well circadian rhythms hormones including cortisol, insulin, leptin, ghrelin, growth hormone, prolactin, sex hormones, adiponectin. Few studies have investigated energy expenditure context resting metabolic rate (RMR) total (TEE) found no significant with RF. Changes however do occur are different non-Ramadan days. Weight variable typically modest wise inter-individual variation. As its direct relevance many religious observers, understanding may implications on weight loss strategies even broader potential implications. This review examines current knowledge aspects balance RF, common model learn also map out healthier outcomes such settings.

Language: Английский

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Effect of diurnal fasting on sleep during Ramadan: a systematic review and meta-analysis

Sleep And Breathing, Journal Year: 2019, Volume and Issue: 24(2), P. 771 - 782

Published: Dec. 12, 2019

Language: Английский

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Impact of Ramadan diurnal intermittent fasting on the metabolic syndrome components in healthy, non-athletic Muslim people aged over 15 years: a systematic review and meta-analysis

British Journal Of Nutrition, Journal Year: 2019, Volume and Issue: 123(1), P. 1 - 22

Published: Oct. 4, 2019

Abstract Studies on the impact of Ramadan diurnal intermittent fasting (RDIF) metabolic syndrome (MetS) components among healthy Muslims observing month have yielded contradictory results. This comprehensive meta-analysis aimed to obtain a more stable estimate effect size during MetS components, examine variability studies, assess generalisability reported results and perform subgroup analyses for associated factors. We searched CINAHL, Cochrane, EBSCOhost, Google Scholar, ProQuest Medical, PubMed/MEDLINE, ScienceDirect, Scopus Web Science databases relevant studies published from 1950 March 2019. The analysed were: waist circumference (WC), systolic blood pressure (SBP), plasma/serum glucose (FG), TAG, HDL-cholesterol. identified eighty-five (4326 participants in total) that were conducted twenty-three countries between 1982 RDIF-induced sizes small reductions WC (no. K = 24, N 1557, Hedges’ g −0·312, 95 % CI −0·387, −0·236), SBP ( 22, 1172, −0·239, −0·372, −0·106), FG 51, 2318, −0·101, −0·260, 0·004) TAG 63, 2862, −0·088, −0·171, −0·004) increase HDL-cholesterol 57, 2771, 0·150, 0·064, 0·236). concluded people, RDIF shows improvement five components: WC, SBP, HDL.

Language: Английский

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Intermittent Fasting and Metabolic Health: From Religious Fast to Time‐Restricted Feeding

Obesity, Journal Year: 2020, Volume and Issue: 28(S1)

Published: July 1, 2020

Over the past 10 to 15 years, intermittent fasting has emerged as an unconventional approach reduce body weight and improve metabolic health beyond simple calorie restriction. In this review, we summarize findings related Ramadan Sunnah fasting. We then discuss role of caloric restriction not only intervention for control, but importantly, a strategy healthy aging longevity. Finally, review four most common (IF) strategies used date management cardiometabolic health. Weight loss is after IF does appear be different than daily when compared directly. may also provide additional benefit, such insulin sensitization, that independent from loss. While no specific regimen stands out superior at time, there indeed heterogeneity in responses these diets. This suggests one dietary ideally suited every individual. Future studies should consider tailoring prescriptions, including IF, based on advanced phenotyping genotyping prior diet initiation.

Language: Английский

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A systematic review, meta-analysis, and meta-regression of the impact of diurnal intermittent fasting during Ramadan on body weight in healthy subjects aged 16 years and above

European Journal of Nutrition, Journal Year: 2020, Volume and Issue: 59(6), P. 2291 - 2316

Published: March 10, 2020

Language: Английский

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Islamic fasting leads to an increased abundance of Akkermansia muciniphila and Bacteroides fragilis group: A preliminary study on intermittent fasting

The Turkish Journal of Gastroenterology, Journal Year: 2019, Volume and Issue: 30(12), P. 1030 - 1035

Published: Dec. 11, 2019

It has been largely accepted that dietary habits affect intestinal microbiota composition. In this pilot study, we hypothesized time-restricted feeding, which can be regarded as a type of intermittent fasting, may have distinct effect on microbiota. Ramadan fasting is an excellent model to understand how feeding the microbiota.A total nine subjects were included in study during Ramadan, consisting 17 h fasting/day 29-day period. Stool samples collected at baseline and day end Ramadan. 16S rRNA qPCR assay performed for quantification Akkermansia muciniphila, Faecalibacterium prausnitzii, Bifidobacterium spp., Lactobacillus Bacteroides fragilis group, Enterobacteriaceae. Blood also test metabolic nutritional parameters.A significantly increased abundance A. muciniphila B. group was observed all after Islamic when compared with levels (p=0.004 0.008, respectively). Serum glucose cholesterol reduced (p<0.01 p=0.009, respectively).Islamic represents leads increase considered healthy gut members. Although should tested larger sample size, there are very limited number studies literature human subjects. Thus, our present findings contribute understanding fasting-gut interaction.

Language: Английский

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