Nutrition, Physical Activity, and Other Lifestyle Factors in the Prevention of Cognitive Decline and Dementia

Nutrients, Journal Year: 2021, Volume and Issue: 13(11), P. 4080 - 4080

Published: Nov. 15, 2021

Multiple factors combined are currently recognized as contributors to cognitive decline. The main independent risk factor for impairment and dementia is advanced age followed by other determinants such genetic, socioeconomic, environmental factors, including nutrition physical activity. In the next decades, a rise in cases expected due largely aging of world population. There no hitherto effective pharmaceutical therapies treat age-associated dementia, which underscores crucial role prevention. A relationship among diet, activity, lifestyle with function has been intensively studied mounting evidence supporting these development decline chief cause disability globally. Several dietary patterns, foods, nutrients have investigated this regard, some encouraging disappointing results. This review presents current effects components, supplements, sleep social engagement on prevention or delay onset age-related dementia.

Language: Английский

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Diet, Obesity, and Depression: A Systematic Review

Journal of Personalized Medicine, Journal Year: 2021, Volume and Issue: 11(3), P. 176 - 176

Published: March 3, 2021

Background: Obesity and depression co-occur in a significant proportion of the population. Mechanisms linking two disorders include immune endocrine system, psychological social mechanisms. The aim this systematic review was to ascertain whether weight loss through dietary interventions has additional effect ameliorating depressive symptoms obese patients. Methods: We systematically searched three databases (Pubmed, Medline, Embase) for longitudinal clinical trials testing intervention people with obesity or depression. Results: Twenty-four studies met eligibility criteria total 3244 included Seventeen examined effects calorie-restricted diets eight supplements (two both). Only diagnosis both majority showed that using diet resulted decreases scores, sizes between ≈0.2 ≈0.6. results were less clear supplements. Conclusions: People appear be specific subgroup depressed patients which might constitute promising personalized treatment approach. reduction may related immunoendocrine psychosocial

Language: Английский

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The Effect of Dietary Interventions on Hypertriglyceridemia: From Public Health to Molecular Nutrition Evidence

Nutrients, Journal Year: 2022, Volume and Issue: 14(5), P. 1104 - 1104

Published: March 5, 2022

Approximately 25–50% of the population worldwide exhibits serum triglycerides (TG) (≥150 mg/dL) which are associated with an increased level highly atherogenic remnant-like particles, non-alcoholic fatty liver disease, and pancreatitis risk. High TG levels could be related to cardiovascular is most prevalent cause mortality in Western countries. The etiology hypertriglyceridemia (HTG) multifactorial can classified as primary secondary causes. Among causes genetic disorders. On other hand, HTG comprise lifestyle factors, medical conditions, drugs. changes, adequate diets nutrition initial steps treat prevent lipid alterations. Dietary intervention for recommended order modify amount macronutrients. Macronutrient distribution changes such fat or protein, low-carbohydrate diets, caloric restriction seem effective strategies reducing levels. Particularly, Mediterranean diet dietary pattern consistent evidence efficacy while use omega-3 supplements consumption component highest number randomized clinical trials (RCT) carried out results on TG. aim this review was provide a better comprehension between human metabolism.

Language: Английский

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Randomised controlled trials for the prevention of cognitive decline or dementia: A systematic review

Ageing Research Reviews, Journal Year: 2022, Volume and Issue: 82, P. 101777 - 101777

Published: Nov. 4, 2022

Language: Английский

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Almond Consumption and Risk Factors for Cardiovascular Disease: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Advances in Nutrition, Journal Year: 2019, Volume and Issue: 10(6), P. 1076 - 1088

Published: March 29, 2019

Language: Английский

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Health Benefits Related to Tree Nut Consumption and Their Bioactive Compounds

International Journal of Molecular Sciences, Journal Year: 2021, Volume and Issue: 22(11), P. 5960 - 5960

Published: May 31, 2021

Long-term studies with regular tree nut consumption have indicated positive outcomes for multiple health benefits. Here, we review the beneficial effects of nuts, highlighting impact on glucose modulation, body weight management, cardiovascular risk, inflammation, oxidative stress, cognitive performance, and gut microbiota. Nuts are important sources nutrients phytochemicals, which, together a healthy lipid profile, could help prevent certain chronic diseases, protect against stress improve thus reducing aging neurodegeneration.

Language: Английский

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Nuts and seeds consumption and risk of cardiovascular disease, type 2 diabetes and their risk factors: a systematic review and meta-analysis

Food & Nutrition Research, Journal Year: 2023, Volume and Issue: 67

Published: Feb. 14, 2023

Objectives: We aimed to systematically review studies and evaluate the strength of evidence on nuts/seeds consumption cardiometabolic diseases their risk factors among adults. Methods: A protocol was pre-registered in PROSPERO (CRD42021270554). searched MEDLINE, Embase, Cochrane Central Register Controlled Trials Scopus up September 20, 2021 for prospective cohort ≥12-week randomized controlled trials (RCTs). Main outcomes were cardiovascular disease (CVD), coronary heart (CHD), stroke type 2 diabetes (T2D), secondary total-/low density lipoprotein (LDL)-cholesterol, blood pressure glycaemic markers. Data extraction bias (RoB) assessments (using RoB 2.0 RoB-NObS) performed duplicate. Effect sizes pooled using random-effects meta-analyses expressed as relative (RR) or weighted mean differences with 95% confidence intervals (CI); heterogeneity quantified I2. One-stage dose-response analyses assessed linear non-linear associations CVD, CHD, T2D. The classified per World Cancer Research Fund criteria. Results: After screening 23,244 references, we included 42 papers from (28 unique cohorts, 1,890,573 participants) 18 RCTs (2,266 participants). In mainly populations low consumption, high versus total inversely associated CVD (RR 0.81; CI 0.75, 0.86; I2 = 67%), mortality (0.77; 0.72, 0.82; 59.3%), CHD (0.82; 0.76, 0.89; 64%), (0.75; 0.65, 0.87; 66.9%) non-fatal (0.85; 0.96; 62.2%). According analyses, 30 g/day RRs similar magnitude. For T2D summary RR intake 0.91 (95% 0.85, 0.97; 24.8%) 0.95 (0.75, 1.21; 82.2%). Intake nuts (median ~50 g/day) lowered (−0.15 mmol/L; −0.22, −0.08; 31.2%) LDL-cholesterol (−0.13 −0.21, −0.05; 68.6%), but not pressure. Findings fasting glucose, HbA1c insulin resistance conflicting. results robust sensitivity subgroup analyses. rated between both probable. There limited suggestive no association stroke. No conclusion could be made Conclusion: is a probable relationship lower mostly driven by possibly part through effects lipids. More research may affect conclusions. specific should further investigated.

Language: Английский

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A Comprehensive Review of Almond Clinical Trials on Weight Measures, Metabolic Health Biomarkers and Outcomes, and the Gut Microbiota

Nutrients, Journal Year: 2021, Volume and Issue: 13(6), P. 1968 - 1968

Published: June 8, 2021

This comprehensive narrative review of 64 randomized controlled trials (RCTs) and 14 systematic reviews and/or meta-analyses provides an in-depth analysis the effect almonds on weight measures, metabolic health biomarkers outcomes, colonic microbiota, with extensive use figures tables. Almonds are a higher energy-dense (ED) food that acts like lower ED when consumed. Recent nut RCTs showed were only had small but significant decrease in both mean body mass fat mass, compared to control diets. The biological mechanisms for almond include enhanced displacement other foods, decreased macronutrient bioavailability net metabolizable energy (ME), upregulation acute signals reduced hunger, elevated satiety increased resting expenditure. intake 42.5 g/day significantly lowered low-density lipoprotein cholesterol (LDL-C), 10-year Framingham estimated coronary heart disease (CHD) risk associated cardiovascular (CVD) medical expenditures. Diastolic blood pressure (BP) was modestly consumed at >42.5 or >6 weeks. suggest possible emerging benefits such as cognitive performance, improved rate variability under mental stress, facial skin aging from exposure ultraviolet (UV) B radiation. Eight show can support microbiota by promoting microflora richness diversity, increasing ratio symbiotic pathogenic microflora, concentrations health-promoting bioactives. premier healthy snack precision nutrition diet plans.

Language: Английский

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Tree Nut and Peanut Consumption and Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Advances in Nutrition, Journal Year: 2023, Volume and Issue: 14(5), P. 1029 - 1049

Published: May 5, 2023

Cardiovascular disease (CVD) is the leading cause of death globally. Habitual consumption tree nuts and peanuts associated with cardioprotective benefits. Food-based dietary guidelines globally recommend as a key component healthy diet. This systematic review meta-analysis were conducted to examine relationship between nut peanut risk factors for CVD in randomized controlled trials (RCTs) (PROSPERO: CRD42022309156). MEDLINE, PubMed, CINAHL, Cochrane Central databases searched up 26 September, 2021. All RCT studies that assessed effects or any dose on included. Review Manager software was used conduct random effect outcomes from RCTs. Forest plots generated each outcome, between-study heterogeneity estimated using I

Language: Английский

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The Relationship of Tree Nuts and Peanuts with Adiposity Parameters: A Systematic Review and Network Meta-Analysis

Nutrients, Journal Year: 2021, Volume and Issue: 13(7), P. 2251 - 2251

Published: June 30, 2021

The network meta-analysis and systematic review conducted aim to comparatively assess the effects of tree nuts peanuts on body weight (BW), mass index (BMI), waist circumference (WC), fat percentage (BF%). A search up 31 December 2020 was performed. random-effects following PRISMA-NMA statement. total 105 randomized controlled trials (RCTs) with measures BW (n = 6768 participants), BMI 2918), WC 5045), BF% 1226) were included. transitivity assumption met based baseline characteristics. In comparisons nut consumption versus a control diet, there no significant increase observed in any adiposity-related examined except for hazelnut-enriched diets, which raised WC. Moreover, almond-enriched diets significantly reduced compared diet pistachio-, mixed nuts-, diets. subgroup analyses only RCTs, designed whether affected loss, almonds associated walnuts %BF. evidence supports that: (1) peanut do not influence adiposity, (2) circumference.

Language: Английский

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