Microbial Biosurfactant as an Alternate to Chemical Surfactants for Application in Cosmetics Industries in Personal and Skin Care Products: A Critical Review

BioMed Research International, Journal Year: 2023, Volume and Issue: 2023(1)

Published: Jan. 1, 2023

Cosmetics and personal care items are used worldwide administered straight to the skin. The hazardous nature of chemical surfactant utilized in production cosmetics has caused alarm on a global scale. Therefore, bacterial biosurfactants (BS) becoming increasingly popular industrial product as biocompatible, low‐toxic alternative surfactant. Chemical surfactants can induce allergic responses skin irritations; thus, they should be replaced with less harmful substances for health. cosmetic industry seeks novel biological alternatives replace compounds improve qualities. Most these chemicals have origin obtained from plant, bacterial, fungal, algal sources. Various molecules intriguing capabilities, such biosurfactants, vitamins, antioxidants, pigments, enzymes, peptides. These safe, biodegradable, environmentally friendly than options. Plant‐based saponins, offer numerous advantages over synthetic surfactants, i.e., nontoxic, nature. Saponins promising source natural various academic applications. However, microbial glycolipids lipopeptides been biotechnology due their multifunctional character, including detergency, emulsifying, foaming, moisturizing capabilities. In addition, some them potential antibacterial agents. this review, we like enlighten application replacing existing skincare pharmaceutical formulations antibacterial, surface moisturizing, low toxicity characteristics.

Language: Английский

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Lactiplantibacillus (Lactobacillus) plantarum as a Complementary Treatment to Improve Symptomatology in Neurodegenerative Disease: A Systematic Review of Open Access Literature

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(5), P. 3010 - 3010

Published: March 5, 2024

This systematic review addresses the use of Lactiplantibacillus (Lactobacillus) plantarum in symptomatological intervention neurodegenerative disease. The existence gut microbiota dysbiosis has been associated with systemic inflammatory processes present disease, creating opportunity for new treatment strategies. involves modifying strains that constitute to enhance synaptic function through gut–brain axis. Recent studies have evaluated beneficial effects on motor and cognitive symptomatology, alone or combination. includes 20 research articles (n = 3 human n 17 animal models). main result this was combination produced improvements symptomatology related However, one included reported negative after administration plantarum. provides current relevant information about probiotic pathologies such as Alzheimer’s Parkinson’s disease Multiple Sclerosis.

Language: Английский

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Probiotics for Neurodegenerative Diseases: A Systemic Review

Microorganisms, Journal Year: 2023, Volume and Issue: 11(4), P. 1083 - 1083

Published: April 20, 2023

Neurodegenerative disorders (ND) are a group of conditions that affect the neurons in brain and spinal cord, leading to their degeneration eventually causing loss function affected areas. These can be caused by range factors, including genetics, environmental lifestyle choices. Major pathological signs these diseases protein misfolding, proteosomal dysfunction, aggregation, inadequate degradation, oxidative stress, free radical formation, mitochondrial dysfunctions, impaired bioenergetics, DNA damage, fragmentation Golgi apparatus neurons, disruption axonal transport, dysfunction neurotrophins (NTFs), neuroinflammatory or neuroimmune processes, neurohumoral symptoms. According recent studies, defects imbalances gut microbiota directly lead neurological through gut-brain axis. Probiotics ND recommended prevent cognitive which is major symptom diseases. Many vivo clinical trials have revealed probiotics (Lactobacillus acidophilus, Bifidobacterium bifidum, Lactobacillus casei, etc.) effective candidates against progression ND. It has been proven inflammatory process stress modulated modifying with help probiotics. As result, this study provides an overview available data, bacterial variety, axis defects, probiotics’ mode action averting A literature search on particular sites, PubMed, Nature, Springer Link, identified articles might pertinent subject. The contains following few groups terms: (1) OR (2) disorders. outcomes aid elucidating relationship between effects different neurodegenerative This systematic review will assist discovering new treatments future, as generally safe cause mild side some cases human body.

Language: Английский

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NAD+ Precursors Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR): Potential Dietary Contribution to Health

Current Nutrition Reports, Journal Year: 2023, Volume and Issue: 12(3), P. 445 - 464

Published: June 5, 2023

Language: Английский

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Clinical Evidence on the Potential Beneficial Effects of Probiotics and Prebiotics in Cardiovascular Disease

International Journal of Molecular Sciences, Journal Year: 2022, Volume and Issue: 23(24), P. 15898 - 15898

Published: Dec. 14, 2022

The ‘gut microbiome’—the hundreds of trillions bacteria in the human gastrointestinal tract—serves several functions. gut microbiome includes all microorganisms, bacteria, viruses, protozoa, and fungi tract their genetic material. It helps digest indigestible foods produces nutrients. Through metabolism sugars proteins, it intestinal barrier, immune system, metabolism. Some such as those microbiome, cause disease, but others are essential to our health. These “good” microbes protect us from pathogens. Numerous studies have linked an unhealthy obesity, insulin resistance, depression, cardiometabolic risk factors. To maximize probiotic benefits each case, knowledge bacterial strains how consume them should be increased. This study aims examine prebiotic organisms on cardiovascular health, specifically heart coronary stroke, hypertension. complete research, a literature review was conducted by gathering clinical data. evidence demonstrates beneficial effect probiotics microorganisms which has multiple for overall health especially diseases.

Language: Английский

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Microbiome–Gut–Mucosal–Immune–Brain Axis and Autism Spectrum Disorder (ASD): A Novel Proposal of the Role of the Gut Microbiome in ASD Aetiology

Behavioral Sciences, Journal Year: 2023, Volume and Issue: 13(7), P. 548 - 548

Published: June 30, 2023

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder characterised by deficits in social interaction and communication, as well restricted stereotyped interests. Due of the high prevalence gastrointestinal disorders individuals with ASD, researchers have investigated gut microbiota potential contributor to its aetiology. The relationship between microbiome, gut, brain (microbiome–gut–brain axis) has been acknowledged key factor modulating function behaviour, but connection aetiology ASD not understood. Recently, there increasing attention on immune system, neurological issues particularly relation loss specific species or decrease microbial diversity. It focuses how dysbiosis can affect permeability, metabolites ASD. However, very complete study suggests that consequence disease it practically no effect autistic manifestations. This review diversity microbiome–gut–brain axis development symptoms severity proposal novel role microbiome where ASD-related behaviour turn accentuates manifestations patients via feedback circuit.

Language: Английский

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Gut Microbial Metabolome and Dysbiosis in Neurodegenerative Diseases: Psychobiotics and Fecal Microbiota Transplantation as a Therapeutic Approach—A Comprehensive Narrative Review

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(17), P. 13294 - 13294

Published: Aug. 27, 2023

The comprehensive narrative review conducted in this study delves into the mechanisms of communication and action at molecular level human organism. addresses complex mechanism involved microbiota-gut-brain axis as well implications alterations microbial composition patients with neurodegenerative diseases. pathophysiology diseases neuronal loss or death is analyzed, main metabolites bidirectional through axis. In addition, interventions targeting gut microbiota restructuring fecal transplantation use psychobiotics-pre- pro-biotics-are evaluated an opportunity to reduce symptomatology associated neurodegeneration these pathologies. This provides valuable information facilitates a better understanding neurobiological be addressed treatment

Language: Английский

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The Alterations of Gut Microbiome and Lipid Metabolism in Patients with Spinal Muscular Atrophy

Neurology and Therapy, Journal Year: 2023, Volume and Issue: 12(3), P. 961 - 976

Published: April 27, 2023

Spinal muscular atrophy (SMA) can cause multiple system dysfunction, especially lipid metabolic disorders, for which management strategies are currently lacking. Microbes related to metabolism and the pathogenesis of neurological diseases. This study aimed preliminarily explore alterations in gut microbiota SMA potential relationship between altered disorders. Fifteen patients with 17 gender- age-matched healthy controls were enrolled study. Feces fasting plasma samples collected. 16S ribosomal RNA sequencing nontargeted metabolomics analysis performed correlation differential metabolites. No significant difference was found microbial diversity (α- β-diversity) control groups, both groups having a relatively similar community structure. However, compared group, group showed an increased relative abundance genera Ruminiclostridium, Gordonibacter, Enorma, Lawsonella, Frisingicoccus, Anaerofilum decreased Catabacter, Howardella, Marine_Methylotrophic_Group_3, Lachnospiraceae_AC2044_group. The concurrent metabolomic that had 56 different kinds metabolite levels than did group. Additionally, Spearman suggested metabolites above-mentioned microbiota. microbiome differed subjects. may be disorders SMA. further is necessary clarify mechanism develop improve complications

Language: Английский

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Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barrier in APP/PS1 mice

Frontiers in Neuroscience, Journal Year: 2025, Volume and Issue: 19

Published: Feb. 4, 2025

Background Gut microbiota dysbiosis is closely related to the occurrence and progression of Alzheimer’s disease (AD). The destruction intestinal mucosal barrier caused by a decrease in short-chain fatty acids (SCFAs) plays key role gut dysbiosis-induced neuroinflammation AD. Our previous research confirmed for first time that manual acupuncture (MA) can benignly modulate dysbiosis, alleviating barrier. However, regulatory effect MA on SCFAs remains elusive, underlying mechanism which improves function requires elucidation. Methods In APP/PS1 (Am) group, was applied at Baihui (GV20), Yintang (GV29), Zusanli (ST36). Probiotics were delivered probiotic (Ap) group. Alterations spatial learning memory, function, feces serum, expression FFAR3 NF-κB, inflammatory cytokines evaluated each Results Compared with those C57BL/6 control (Cc) cognitive ability significantly decreased, obviously integrity drastically impaired, NF-κB levels IL-1β TNF- α increased (Ac) These changes reversed probiotics. Conclusion reduce inflammation alleviate mice. SCFAs/FFAR3/NF-κB may be important targets through regulates function.

Language: Английский

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Impact of Macrolide Antibiotics on Gut Microbiota Diversity with Age-Specific implications and Scientific Insights

Medicine in Microecology, Journal Year: 2025, Volume and Issue: unknown, P. 100122 - 100122

Published: Feb. 1, 2025

Language: Английский

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