Cardiovascular and Metabolic Science,
Journal Year:
2023,
Volume and Issue:
34(3), P. 127 - 141
Published: Jan. 1, 2023
El
infarto
y
la
isquemia
del
miocardio
sin
lesiones
coronarias
obstructivas
(MINOCA,
INOCA,
por
sus
siglas
en
inglés)
son
conceptos
controvertidos.Una
lesión
no
obstructiva
≤
50%
implica
presencia
de
aterosclerosis
que
puede
complicarse
con
ruptura
o
erosión
placa
trombosis
presentes
los
síndromes
coronarios
agudos,
cuales
tiempo
dependientes
fácilmente
detectables
imagen
intravascular.El
mayor
registro
MINOCA
es
el
sueco,
reportó
9,092
pacientes
utilizando
angiografía
coronaria
únicamente,
intravascular,
lo
deja
poco
claro
si
hubo
disección,
placa;
así
como
tampoco
especifica
enfermedad
Takotsubo,
miocarditis
cardiomiopatía.El
diagnóstico
debe
tener
elevación
marcadores
enzimas
cardiacas,
cambios
electrocardiográficos
anomalías
movilidad
segmentaria,
e
intravascular.INOCA
un
estudio
inductor
positivo,
coronaria,
fisiológico
coronario
hiperémico
determinación
flujo
reserva
fraccional
(FFR,
(CFR,
para
certeza.
ABSTRACTMyocardial
infarction
with
non-obstructive
coronary
arteries
(MINOCA),
and
ischemia
(INOCA)
are
controversial
concepts.A
lesion
stenosis
in
acute
syndromes
may
have
an
atherosclerosis
process
plaque
erosion
or
fracture
thrombus
formation,
which
timedependent
not
easily
shown
by
intravascular
imaging
methods.The
largest
Registry
is
the
Swedish,
included
patients
MINOCA,
supported
only
angiography
without
imaging,
led
to
unknown
dissection,
erosion,
fracture,
did
discriminate
myocarditis,
cardiomyopathies.MINOCA
must
positive
cardiac
markers
enzymes,
electrocardiographic
(ECG)
changes,
regional
wall
motion
abnormalities
(WMA),
angiography,
image
confirm
diagnosis.In
INOCA
a
ischemic
stress
test,
hyperemic
physiologic
studies
as
fractional
flow
reserve
(FFR),
(CFR)
should
be
present
diagnosis.
Myocardial
and,
arteries,
COMECITE
recommendations
Infarto
arterias
obstructivas,
recomendaciones
Frontiers in Microbiology,
Journal Year:
2024,
Volume and Issue:
14
Published: Jan. 5, 2024
The
imbalance
of
microbial
composition
and
diversity
in
favor
pathogenic
microorganisms
combined
with
a
loss
beneficial
gut
microbiota
taxa
results
from
factors
such
as
age,
diet,
antimicrobial
administration
for
different
infections,
other
underlying
medical
conditions,
etc.
Probiotics
are
known
their
capacity
to
improve
health
by
stimulating
the
indigenous
microbiota,
enhancing
host
immunity
resistance
infection,
helping
digestion,
carrying
out
various
functions.
Concurrently,
metabolites
produced
these
microorganisms,
termed
postbiotics,
which
include
compounds
like
bacteriocins,
lactic
acid,
hydrogen
peroxide,
contribute
inhibiting
wide
range
bacteria.
This
review
presents
an
update
on
using
probiotics
managing
treating
human
diseases,
including
complications
that
may
emerge
during
or
after
COVID-19
infection.
Current Opinion in Endocrinology Diabetes and Obesity,
Journal Year:
2024,
Volume and Issue:
31(3), P. 122 - 130
Published: April 8, 2024
This
review
critically
examines
interconnected
health
domains
like
gut
microbiome,
bone
health,
interleukins,
chronic
periodontitis,
and
coronavirus
disease
2019
(COVID-19),
offering
insights
into
fundamental
mechanisms
clinical
implications,
contributing
significantly
to
healthcare
biomedical
research.
Nutrients,
Journal Year:
2025,
Volume and Issue:
17(4), P. 690 - 690
Published: Feb. 14, 2025
Background/Objectives:
Gut
microbiome
modulation
through
probiotics
is
a
growing
area
of
research,
with
several
investigations
reporting
beneficial
health
outcomes
for
the
host.
Physical
exercise
has
been
shown
to
impact
gut
diversity.
Emerging
evidence
suggests
that
probiotic
supplementation
can
affect
performance.
However,
mechanisms
and
domain-specific
effects
on
performance
remain
be
elucidated.
This
narrative
review
aims
investigate
potential
underpinning
ergogenic
benefits
further
define
current
base
specific
domains.
Discussion:
The
literature
improved
recovery
after
intense
training
regimes,
enhanced
nutrient
absorption,
alleviation
gastrointestinal
symptoms,
immune
function
may
underpin
sporting
A
small
number
trials
also
suggest
improve
symptoms
anxiety.
research
warranted
this
topic.
most
substantial
improvements
in
endurance
performance,
whilst
only
few
have
investigated
upon
power
albeit
promising
results.
Conclusions/Future
Perspectives:
In
summary,
performance;
future
wish
explore
action.
Microorganisms,
Journal Year:
2023,
Volume and Issue:
11(9), P. 2160 - 2160
Published: Aug. 26, 2023
The
fine
balance
between
symbiotic
and
potentially
opportunistic
and/or
pathogenic
microorganisms
can
undergo
quantitative
alterations,
which,
when
associated
with
low
intestinal
biodiversity,
could
be
responsible
for
the
development
of
gut
inflammation
so-called
“intestinal
dysbiosis”.
This
condition
is
characterized
by
disbalance
a
synergistic
mechanism
involving
mucosal
barrier,
neuroendocrine
system,
immune
system
that
results
in
an
acute
inflammatory
response
induced
different
causes,
including
viral
or
bacterial
infections
digestive
tract.
More
frequently,
however,
dysbiosis
slowly
subtly
subliminal
causal
factors,
resulting
chronic
related
to
diseases
affecting
tract
other
organs
apparatuses.
Studies
on
animal
models,
together
studies
humans,
highlight
significant
role
microbiota
microbiome
occurrence
conditions
such
as
metabolic
syndrome
cardiovascular
(CVDs);
neurodegenerative,
urologic,
skin,
liver,
kidney
pathologies;
premature
aging.
blood
translocation
fragments
has
been
found
one
processes
linked
possible
“metabolic
endotoxemia”
systemic
inflammation,
increased
risk
oxidative
stress
diseases.
In
this
context,
supplementation
probiotic
strains
shown
restore
eubiosis,
especially
if
administered
long-term
treatments.
aim
review
describe
anti-inflammatory
effects
specific
observed
clinical
trials
respective
indications,
highlighting
differences
efficacy
depending
strain,
formulation,
time
duration
treatment,
dosage
used.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(5), P. 720 - 720
Published: March 1, 2024
In
recent
years,
postbiotics
have
increased
in
popularity,
but
the
potential
relevancy
of
for
augmenting
exercise
performance,
recovery,
and
health
is
underexplored.
A
systematic
literature
search
Google
Scholar
PubMed
databases
was
performed
with
main
objective
being
to
identify
summarize
current
body
scientific
on
postbiotic
supplementation
outcomes
related
performance
recovery.
Inclusion
criteria
this
review
consisted
peer-reviewed,
randomized,
double-blind,
placebo-controlled
trials,
a
population
including
healthy
men
or
women
>18
years
age.
Studies
required
incorporation
regimen
an
outcome
linked
exercise.
Search
terms
included
paraprobiotics,
Tyndallized
probiotics,
ghost
biotics,
heat-killed
inactivated
nonviable
exercise,
Only
investigations
written
English
were
considered.
Nine
peer-reviewed
manuscripts
two
published
abstracts
from
conference
proceedings
reviewed.
Supplementation
periods
ranged
13
days
12
weeks.
total
477
subjects
participated
studies
(n
=
16–105/study)
reported
results
spanning
variety
recovery
lost
strength,
composition,
perceptual
fatigue
soreness,
daily
logs
physical
conditions,
changes
mood
states,
biomarkers
associated
muscle
damage,
inflammation,
immune
modulation,
oxidative
stress.
Early
evidence
has
provided
some
indication
that
may
help
support
mood,
reduce
fatigue,
increase
readiness
athletes
across
several
weeks
training.
However,
more
research
needed
further
understand
how
augment
health,
resiliency,
Future
should
include
longer
wider
competitive
exercising
populations.
Frontiers in Cardiovascular Medicine,
Journal Year:
2025,
Volume and Issue:
12
Published: Feb. 4, 2025
Atrial
cardiomyopathy
is
a
multifaceted
heart
disease
characterized
by
structural
and
functional
abnormalities
of
the
atria
closely
associated
with
atrial
fibrillation
its
complications.
Its
etiology
involves
number
factors,
including
genetic,
infectious,
immunologic,
metabolic
factors.
Recent
research
has
highlighted
critical
role
gut
microbiota
in
pathogenesis
cardiomyopathy,
this
consistent
gut–heart
axis
having
major
implications
for
cardiac
health.
The
aim
work
to
bridge
knowledge
gap
regarding
interactions
between
particular
focus
on
elucidating
mechanisms
which
dysbiosis
may
induce
remodeling
dysfunction.
This
article
provides
an
overview
changes
composition
effects
metabolites.
We
also
discuss
how
diet
exercise
affect
influencing
microbiota,
as
well
possible
future
therapeutic
approaches
targeting
axis.
A
healthy
can
prevent
disease,
but
ecological
lead
variety
symptoms,
induction
disease.
pathophysiological
aspects
impact
structure
function,
strategies
exploring
modulation
treatment
cardiomyopathy.
Finally,
we
fecal
transplantation
oral
probiotics
or
prebiotics.
Our
study
highlights
importance
homeostasis
cardiovascular
health
suggests
that
targeted
interventions
pave
way
innovative
preventive