Chronotype and Cancer: Emerging Relation Between Chrononutrition and Oncology from Human Studies

Nutrients, Journal Year: 2025, Volume and Issue: 17(3), P. 529 - 529

Published: Jan. 31, 2025

Fasting-feeding timing is a crucial pattern implicated in the regulation of daily circadian rhythms. The interplay between sleep and meal underscores importance maintaining alignment order to avoid creating metabolic environment conducive carcinogenesis following molecular systemic disruption performance immune function. chronicity such condition may support initiation progression cancer through variety mechanisms, including increased oxidative stress, suppression, activation proliferative signaling pathways. This review aims summarize current evidence from human studies provide an overview potential mechanisms underscoring role chrononutrition (including time-restricted eating) on risk. Current shows that morning chronotype, suggesting physiological rhythms eating timing, associated with lower risk cancer. Also, early prolonged nighttime fasting were also suggests chronotype influences cell cycle regulation, modulation pathways inflammation, gut microbiota fluctuations. In conclusion, although there are no clear guidelines this matter, emerging supports hypothesis time-related (i.e., time/calorie-restricted feeding intermittent/periodic fasting) could potentially lead reduced

Language: Английский

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Chrononutrition patterns and their association with body weight: Differences across multiple chronotypes

Endocrinología Diabetes y Nutrición (English ed ), Journal Year: 2025, Volume and Issue: 72(1), P. 4 - 13

Published: Jan. 1, 2025

Language: Английский

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Chrononutrition in type 2 diabetes mellitus and obesity: A narrative review

Diabetes/Metabolism Research and Reviews, Journal Year: 2024, Volume and Issue: 40(2)

Published: Feb. 1, 2024

Abstract Chrononutrition is a nutritional regimen that follows our biological clock, marked by the changes in metabolism occur during day. This includes distribution of energy, regularity and frequency meals, importance these factors for metabolic health. A growing body animal human evidence indicates timing food intake throughout day can have significant beneficial impact on health well‐being individuals. In particular, both meals been associated with obesity, type 2 diabetes mellitus (T2DM), cardiovascular disease, other chronic conditions. Today's busy lifestyle makes many people skip breakfast eat late at night. Eating night has shown to cause circadian misalignment, latter having negative weight control glucose metabolism. Additionally, some studies found relatively strong association between skipping insulin resistance, T2DM. Against backdrop escalating obesity T2DM rates, coupled recognized influence disease evolution control, this review aimed synthesize insights from epidemiological intervention interplay macronutrient consumption, reporting their

Language: Английский

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Chrononutrition in the Prevention and Management of Metabolic Disorders: A Literature Review

Nutrients, Journal Year: 2024, Volume and Issue: 16(5), P. 722 - 722

Published: March 1, 2024

Background: The concept of time-restricted eating (TRE) or feeding (TRF) promotes daily periods and fasting to determine whole-body physiology. Chronic misalignment circadian rhythms chrono-disruption is related an increased risk diverse metabolic disorders. progression non-communicable diseases seems be affected by the timing meals. As a result, intermittent promising approach for their management. aim present literature review examine scrutinize TRE protocols in fields prevention management Methods: This thorough reported associations among rhythm, disorders, diabetes mellitus, obesity, TRE, TRF, dietary habits, disruption, cardiovascular diseases, atherosclerosis, non-alcoholic fatty liver find already existing clinical studies from last decade (2014–2024) most precise scientific online databases, using relevant specific keywords. Several inclusion exclusion criteria were applied only longitudinal, cross-sectional, descriptive, prospective human studies. Results: currently available findings remain scarce suggest that chrononutrition behaviors such as TRF may promote several benefits, mainly body weight control fat loss. Improvements glucose levels lipid profiles are quite controversial since some show little no effect. far concerned, efficacy stronger disease due decline Conclusions: Even if there has been gradual increase few years, providing perspectives, currently, conclusive evidence role Future should well-designed with longer duration larger sample sizes. Moreover, it important best window its feasibility.

Language: Английский

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Intercropping Systems to Modify Bioactive Compounds and Nutrient Profiles in Plants: Do We Have Enough Information to Take This as a Strategy to Improve Food Quality? A Review

Plants, Journal Year: 2024, Volume and Issue: 13(2), P. 194 - 194

Published: Jan. 11, 2024

Various environmental, food security and population health problems have been correlated with the use of intensive agriculture production systems around world. This type system leads to loss biodiversity natural habitats, high usage rates agrochemicals resources, affects soil composition, human health, nutritional plant quality in rural areas. Agroecological intercropping that respect agrobiodiversity, on other hand, can significantly benefit ecosystems, by modifying profile content some health-promoting bioactive compounds species cultivated this system. However, research strategies focuses more benefits they offer less nutrient existing information is scattered. The topic merits further study, given critical impact it could nutrition. aim review therefore collect viable details status into nutrients different regions world unique mixed crops using species, along criteria for combining them, as well analyzed, exemplify possible contributions availability quality.

Language: Английский

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Effects of Early and Late Time-Restricted Feeding on Parameters of Metabolic Health: An Explorative Literature Assessment

Nutrients, Journal Year: 2024, Volume and Issue: 16(11), P. 1721 - 1721

Published: May 31, 2024

Chrono-nutrition (meal timing) aligns food consumption with one’s circadian rhythm. The first meal (e.g., breakfast) likely promotes synchronization of peripheral clocks, thereby supporting metabolic health. Time-restricted feeding (TRF) has been shown to reduce body weight (BW) and/or improve cardiovascular biomarkers. In this explorative literature assessment, 13 TRF randomized controlled trials (RCTs) were selected from PubMed and Scopus evaluate the effects early (eTRF: before 10:30 a.m.) late (lTRF: after 11:30 on parameters Although distinct variations in study design evident between reports, consistently decreased energy intake (EI) BW, improved insulin resistance as well systolic blood pressure. eTRF seemed have a greater beneficial effect than lTRF (HOMA-IR). Importantly, most studies did not appear consider chronotype their evaluation, which may underestimated effects. intervention be promising approach for risk reduction human diseases. To conclusively determine benefits identify clear differences lTRF, future should longer-term (≥8 weeks) well-defined (differences in) windows, include participants chronotypically matching intervention, compare outcomes those control groups without any dietary limitations.

Language: Английский

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Scoping review protocol: The chrononutrition factors in association with glycemic outcomes in adult population

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(2), P. e0313931 - e0313931

Published: Feb. 14, 2025

Chrononutrition, which examines the relationship between circadian rhythms and nutrition, has been associated with glycemic outcomes in adults. However, published data on delayed meal timing, increased frequency frequent breakfast skipping have shown inconsistent due to variations methodologies populations studied. This review presents scoping protocol designed map evidence association chrononutrition factors The methodology framework from Arksey O’Malley will be adapted for this review. Relevant publications searched databases including PubMed, EBSCO Host, ProQuest Central, MEDLINE & Ovid, Scopus Web of Science. focuses original articles January 2014 2024, involving participants aged 18 years older, English, encompassing experimental observational studies. A comprehensive keyword search strategy developed identify relevant articles. Two reviewers independently screen abstracts titles determine eligibility. Subsequently, full text potentially eligible reviewed by additional independent reviewer final inclusion, screening being verified two reviewers, interrater reliability conducted. Data included extracted, collated charted summarize methods, key findings. Preferred Reporting Items Systematic Reviews Meta-Analyses extension Scoping (PRISMA-ScR) checklist used guide development protocol. represents a novel approach among We anticipate findings provide stakeholder crucial evidence-based information effective intervention manage outcome prospectively registered Open Science Framework ( https://doi.org/10.17605/OSF.IO/PA9BU ).

Language: Английский

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Beyond the Scales: A Qualitative Study on the Biopsychosocial Impacts of Time-Restricted Eating in Free-Living Individuals

Obesities, Journal Year: 2025, Volume and Issue: 5(1), P. 10 - 10

Published: Feb. 18, 2025

Time-restricted eating (TRE) has gained attention as an effective approach for weight management and overall well-being by focusing on limiting the window, rather than reducing calories. This study explores biopsychosocial impacts of TRE in free-living individuals using a qualitative design. Twenty-one adults (aged 27–60 years) from Western Australia who had practised at least three months were purposively recruited, semi-structured interviews conducted. The data analysed thematic analysis to identify key themes. participants reported range benefits, including loss, reduced joint pain, better digestion, improved mental clarity, increased energy, more positive body image. Socially, facilitated simplified daily routines but also introduced challenges, such disruptions social interactions family meal dynamics. Some mixed negative reported, changes sleep exercise patterns. These findings highlight TRE’s potential holistic dietary intervention. Further research, particularly well-controlled, randomised controlled trials longitudinal studies, is needed confirm these insights guide their appropriate application clinical public health settings.

Language: Английский

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The Association Between Midpregnancy Food Intake Timing Patterns and Gestational Weight Gain

Journal of Women s Health, Journal Year: 2025, Volume and Issue: unknown

Published: April 14, 2025

Background: This article aims to characterize midpregnancy food timing profiles and examine their association with gestational weight gain (GWG). Materials Methods: secondary data analysis of a randomized controlled trial two diabetes screening approaches included 641 individuals primary exposures outcomes data. Food indicators (i.e., first last eating episode time, caloric midpoint the total window) were assessed using 24-hour dietary recalls conducted in midpregnancy. Latent profile was used identify distinct based on these indicators. Regression analyses explored associations between individual intake indicators, profiles, GWG. Results: We identified four profiles: extended window (n = 133; earliest longest window), restricted 120; latest shortest early 188; midpoint), typical 200; aligning sample median). Participants (vs. profile) had an increased risk insufficient GWG (unadjusted relative [RR] 1.85, 95% confidence interval [CI] 1.12, 3.05). Each hour increase associated 0.39 kg (0.03, 0.75) higher Both attenuated adjusted models no longer statistically significant models. Conclusions: but not independently These findings suggest that may play major role

Language: Английский

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Impact of chrono-nutrition profile on academic performance with reference to demographic characteristics of young adults: A cross-sectional study

Nutrition and Health, Journal Year: 2025, Volume and Issue: unknown

Published: April 21, 2025

Background The circadian rhythm, which governs sleep patterns and dietary habits, is crucial to people's metabolic health. Disruptions these established routines can result in serious disorders may impact youngster's academic performance. Aim This study aimed assess the chrono-nutrition profile of university students its on It also explored relationship between demographic characteristics, patterns, scores. Methods A cross-sectional was conducted from May 2023 July how disruptions eating sleeping performance through data collected 288 young adults (18–30 years). Participants completed Chrono-nutrition Profile Academic Performance Questionnaire ( Veronda et al., 2020 ) provided information responses self-awareness questions. Results average age participants 21 years, with 19% being males 81% females; 56.3% were day scholars 42.4% hostelites. duration sample workdays 7 h, compared 9 h days off. mean score indicated excellent (score: 25–32). actual window not statistically significant (p = 0.905). Similarly, skipping breakfast did show a association scores 0.693). Conclusion associated scores, as there variability habits windows both We recommend that future research gather prospective further investigate findings.

Language: Английский

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