Molecules,
Journal Year:
2022,
Volume and Issue:
28(1), P. 207 - 207
Published: Dec. 26, 2022
Supercritical
CO2
extraction
(SCCO2)
of
cannabis
oil
from
Indian
(Cannabis
indica)
leaves
was
optimized
through
a
central
composite
design
using
pressure
(150–250
bar),
temperature
(30–50
°C)
and
time
(1–2
h).
From
the
regression
model,
optimal
pressure,
were
250
bar,
43
°C
1.7
h,
respectively
resulting
in
experimental
yield
4.9
wt%
via
SCCO2
extraction.
The
extract
contained
cannabidiol,
tetrahydrocannabivarin,
Δ9-tetrahydrocannabinol
Δ8-tetrahydrocannabinol
as
well
two
terpenoids
such
cis-caryophyllene
α-humulene.
Besides
oil,
raffinate
biomass
utilized
to
polyphenols
water
medium.
Cannabis
extractive
investigated
for
their
half-maximal
inhibitory
concentration
(IC50)
values,
which
found
be
1.3
0.6
mg/mL,
respectively.
This
is
comparable
commercially
available
antioxidant
butylated
hydroxytoluene
with
an
IC50
value
0.5
mg/mL.
work
on
cannabinoids
other
valuable
bioactive
compounds
provides
environmentally
sustainable
technique
valorize
leaves.
The Canadian Journal of Chemical Engineering,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 19, 2025
Abstract
In
this
study,
supercritical
fluid
extraction
(SFE)
was
used
to
extract
cannabis
essential
oil
and
cannabinoids
from
the
same
matrix
by
changing
decarboxylation
conditions
CO
2
density.
Cannabis
extracted
at
90
bar
50°C
(0.288
g/cm
3
density),
it
mainly
composed
of
α‐pinene,
eucalyptol,
β‐caryophyllene,
selinene.
Subsequently,
carried
out
on
vegetable
matter
operating
105°C
for
15
min
and,
then,
120°C
1
h.
The
largest
cannabidiol
(2.96%
w/w)
yield
obtained
when
SFE
performed
100
40°C
(0.623
density).
An
effective
online
fractional
separation
compounds
also
SFE,
since
no
cuticular
waxes
were
detected
in
GC–MS
traces
products
interest.
Operating
way,
expensive,
time‐consuming,
polluting
post‐processing
steps
not
required,
producing
a
ready‐to‐use
market.
Journal of Natural Fibers,
Journal Year:
2024,
Volume and Issue:
21(1)
Published: June 27, 2024
Industrial
hemp
cultivation
was
restricted
years
ago
in
most
countries,
thus
wiping
out
centuries
of
science
and
genetic
resources.
It
is
only
since
the
1990s
that
has
been
experiencing
its
renaissance,
which
nowadays
driven
by
new
strategies.
The
objective
review
to
compile
summarize
latest
research
achievements.
focus
on
from
2018
2023.
VOSviewer
software
used
define
main
areas
trends.
Most
articles
were
discussed,
among
others
determination
average
yield
loss
due
water
stress
(8.7
Mg
ha−1)
low
temperatures
(0.4
ha−1);
increase
up
25%
achieving
rejecting
smallest
seeds;
or
definition
optimum
dose
sewage
sludge
application
(25
ha−1).
Regarding
composition
properties:
identification
caflanone
flavonoid
(selective
activity
against
certain
neoplasms);
71
compounds
(monoterpenes,
sesquiterpenes
CBs)
EO;
antioxidant
capacity
EO
(63
mg
TE
g−1
438
g−1);
comparison
content
monoicous,
female
male
inflorescences
(0.10%,
0.15%
0.07%
respectively).
current
possibilities
using,
e.g.
for
phytoremediation
bioenergy,
presented.
Also
knowledge
gaps
future
identified.
Plant-based
proteins,
like
those
derived
from
hemp
and
rapeseed
can
significantly
contribute
to
a
balanced
diet
human
daily
nutritional
requirements
by
providing
essential
nutrients
such
as
protein,
fiber,
vitamins,
minerals,
antioxidants.
According
numerous
recent
research
papers
the
consumption
of
plant-based
proteins
has
been
associated
with
health
benefits,
including
reduced
risk
chronic
diseases
heart
disease,
diabetes,
certain
cancers.
diets
are
often
lower
in
saturated
fat
cholesterol
higher
fiber
phytonutrients,
which
support
overall
well-being.
Present
investigates
attributes,
functional
properties,
potential
food
applications
protein
for
use
new
product
development,
focus
on
identifying
anti-nutritional
factors
bioactive
compounds.
Through
comprehensive
analysis,
compounds
were
elucidated,
shedding
light
their
impact
quality
digestibility.
The
study
also
delves
into
properties
unveiling
versatility
various
applications.
Insights
this
deeper
understanding
value
paving
way
further
utilization
innovative
products
enhanced
notable
benefits.
Journal of Agricultural and Food Chemistry,
Journal Year:
2024,
Volume and Issue:
72(23), P. 12975 - 12987
Published: May 28, 2024
This
study
discovered
the
impact
of
high-tunnel
(i.e.,
unheated
greenhouse)
and
open-field
production
on
two
industrial
hemp
cultivars
(SB1
CJ2)
over
their
yield
parameters,
cannabinoid
development,
volatile
profiles.
Development
neutral
cannabinoids
(CBD,
THC,
CBC),
acidic
(CBDA,
THCA,
CBCA),
total
during
floral
maturation
were
investigated.
The
profiles
flowers
holistically
compared
via
HS-SPME-GC/MS.
Findings
indicated
a
high
tunnel
as
an
efficient
practice
for
achieving
greater
weight,
stem
number,
caliper,
especially
in
SB1
cultivar.
Harvesting
high-tunnel-grown
early
flower
could
obtain
CBD
while
complying
with
THC
regulations.
Considering
profiles,
mainly
consisted
mono-
sesquiterpenoids,
well
oxygenated
sesquiterpenoids.
Volatile
analysis
revealed
substantial
profile
to
systems.
Case Studies in Chemical and Environmental Engineering,
Journal Year:
2023,
Volume and Issue:
9, P. 100550 - 100550
Published: Nov. 22, 2023
As
a
versatile
and
multipurpose
plant,
hemp
(Cannabis
sativa
L.)
possesses
immense
potential
for
its
application
in
nutraceuticals,
food
nutrition,
fibre,
construction
material.
However,
broader
industrial
potentials
are
hindered
by
the
lack
of
sufficient
knowledge
on
varietal
differences,
phytochemical
properties,
fibre
processing
techniques,
bioenergy
valorisation
whole
clinical
evidence,
standardised
quality
control
mechanisms.
In
this
context,
we
systematically
reviewed
101
reviews
655
research
papers
to
map
what
already
know
still
need
about
hemp,
across
supply
chain;
from
cultivar
selection
through
production
end
use.
We
literature
based
major
themes
sub-themes.
Existing
spanned
33
sub-themes
which
can
be
classified
under
five
broad
themes:
production,
material,
health,
futures,
education.
The
'material'
theme
(42%)
was
most
researched,
followed
'production'
(27%)
'health'
(19%).
At
sub-theme
level,
one-fifth
articles
covered
composite
material
(n
=
139),
analysis
potency
testing
45),
hempcrete
applications
43),
germination
plantation
techniques
41).
More
than
half
selected
were
published
last
three
years
(2020–2022),
concentrated
mainly
North
America,
Europe,
China.
Cannabidiol,
seed
oil
considered
as
quick
wins
industry
(hemp
champions).
Based
our
review,
have
discussed
various
gaps
priorities
chain,
beginning
early
detection
breed
hurd
residue
address
opportunities
challenges
development
products.
Antibiotics,
Journal Year:
2024,
Volume and Issue:
13(4), P. 369 - 369
Published: April 17, 2024
The
compounds
present
in
hemp
show
multidirectional
biological
activity.
It
is
related
to
the
presence
of
secondary
metabolites,
mainly
cannabinoids,
terpenes,
and
flavonoids,
synergy
their
aim
this
study
was
assess
activity
Henola
Cannabis
sativae
extract
its
combinations
with
selected
carriers
(polyvinyl
caprolactam–polyvinyl
acetate–polyethylene
glycol
graft
copolymer,
magnesium
aluminometasilicate,
hydroxypropyl-β-cyclodextrin)
terms
antimicrobial,
probiotic,
immunobiological
effects.
As
a
result
conducted
research,
antimicrobial
confirmed
relation
following
microorganisms:
Clostridium
difficile,
Listeria
monocytogenes,
Enterococcus
faecalis,
Staphylococcus
aureus,
pyrogenes,
Escherichia
coli,
Klebsiella
pneumoniae,
Salmonella
typhimurium,
Pseudomonas
aereuginosa,
Candida
albicans
(microorganism
count
reduced
from
~102
CFU
mL−1
<10
most
cases).
Additionally,
for
system
hydroxypropyl-β-cyclodextrin,
significant
probiotic
potential
against
bacterial
strains
established
Lactobacillus
acidophilus,
casei,
plantarum,
brevis,
rhamnosus,
reuteri,
Pediococcus
pentosaceus,
Lactococcus
lactis,
fermentum,
Streptococcus
thermophilus
increased
104–107).
In
immunomodulatory
properties,
it
determined
that
tested
systems
caused
changes
IL-6,
IL-8,
TNF-α
levels.
Plants,
Journal Year:
2024,
Volume and Issue:
13(9), P. 1195 - 1195
Published: April 25, 2024
Plant-based
proteins,
like
those
derived
from
hemp
and
rapeseed
can
contribute
significantly
to
a
balanced
diet
meet
human
daily
nutritional
requirements
by
providing
essential
nutrients
such
as
protein,
fiber,
vitamins,
minerals,
antioxidants.
According
numerous
recent
research
papers,
the
consumption
of
plant-based
proteins
has
been
associated
with
health
benefits,
including
reduced
risk
chronic
diseases
heart
disease,
diabetes,
certain
cancers.
diets
are
often
lower
in
saturated
fat
cholesterol
higher
fiber
phytonutrients,
which
support
overall
well-being.
Present
investigates
attributes,
functional
properties,
potential
food
applications
protein
for
use
new
food-product
development,
focus
on
identifying
anti-nutritional
factors
bioactive
compounds.
Through
comprehensive
analysis,
compounds
were
elucidated,
shedding
light
their
impact
quality
digestibility.
The
study
also
delves
into
properties
unveiling
versatility
various
applications.
Insights
this
deeper
understanding
value
paving
way
further
utilization
innovative
products
enhanced
notable
benefits.
Phytochemical Analysis,
Journal Year:
2024,
Volume and Issue:
35(5), P. 927 - 989
Published: June 4, 2024
Organic
molecules
that
bind
to
cannabinoid
receptors
are
known
as
cannabinoids.
These
possess
pharmacological
properties
similar
those
produced
by
Cannabis
sativa
L.
High-performance
liquid
chromatography
(HPLC)
and
ultra-performance
(UPLC,
also
ultra-high-performance
chromatography,
UHPLC)
have
become
the
most
widely
used
analytical
tools
for
detection
quantification
of
phytocannabinoids
in
various
matrices.
HPLC
UPLC
(or
usually
coupled
an
ultraviolet
(UV),
photodiode
array
(PDA),
or
mass
spectrometric
(MS)
detector.
Applied Sciences,
Journal Year:
2025,
Volume and Issue:
15(2), P. 624 - 624
Published: Jan. 10, 2025
Recent
research
has
increasingly
focused
on
the
benefits
of
various
plants,
including
hemp,
which
gained
prominence
for
its
medical
and
industrial
applications.
The
incorporation
hemp
in
beer
brewing
further
popularized
this
age-old
beverage.
In
several
countries,
cultivation
containing
a
maximum
0.2%
THC
(Δ9-tetrahydrocannabinol)
been
legalized,
leading
to
growing
recognition
plant’s
potential
derived
products.
objective
study
was
produce
infused
with
dried
inflorescences.
Additionally,
sensory
analysis
conducted
panelists
evaluate
drinkability
produced
beer,
revealing
that
both
variants
added
inflorescence
received
higher
scores.
addition
during
boiling
resulted
specific
gravity
(1.01071
mg/L)
regard
control
(1.01015
subjected
dry
hemping
(1.01018
mg/L).
Generally,
significant
difference
most
physical–chemical
parameters
noted
sample
boiled
inflorescence,
while
dry-hemped
showed
no
statistically
difference.
only
property
between
all
samples,
control,
bitterness,
exhibited
change
relation
mode
addition.
Comprehensive Reviews in Food Science and Food Safety,
Journal Year:
2025,
Volume and Issue:
24(1)
Published: Jan. 1, 2025
Abstract
This
review
focuses
on
antimicrobial
packaging
for
food
safety,
critically
examining
the
activity
and
efficacy
of
cannabinoids
against
commonly
found
microorganisms
exploring
their
mechanisms.
Specifically,
considers
derived
from
industrial
hemp
plants,
which
are
characterized
by
low
levels
psychoactive
components.
It
also
outlines
viable
strategies
to
control
sustained
release
packaging,
enabling
extended
storage
enhanced
safety
products.
Research
demonstrates
that
effective
both
foodborne
bacteria
fungi,
with
action
primarily
attributed
microbial
membrane
instability.
Cannabinoids
can
be
utilized
prepare
films
edible
coatings;
however,
number
studies
in
this
area
remains
limited.
The
potential
contribute
intelligent
systems
is
discussed,
an
emphasis
regulatory
aspects
challenges
associated
incorporating
into
packaging.
Finally,
identifies
future
research
directions
address
current
limitations
advance
hemp‐based
solutions.