Preparation of polymer composites with electrostatic spinning promotes wound regeneration: A review DOI Creative Commons

Wanying Yang,

Cong Yang,

Guanghui Jing

et al.

AIP Advances, Journal Year: 2024, Volume and Issue: 14(9)

Published: Sept. 1, 2024

Wound dressings play a critical role in promoting healing by protecting wounds from external contaminants and providing an optimal environment for tissue regeneration. Traditional dressings, such as gauze cotton, offer basic physical barriers but lack the ability to maintain moist wound environment, which is essential healing. Modern particularly those incorporating electrospun nanofibers, have emerged advanced solutions that can sustain moisture, absorb exudate, support cell growth migration. This Review covers recent advances electrospinning technologies design of composite materials integrate natural synthetic polymers, bioactive agents, nanomaterials enhance In addition, it highlights key studies demonstrating efficacy these composites various models. The primary objective this inspire guide future research endeavors, address existing limitations, shed light on promising prospects field

Language: Английский

Advancements in 3D-printable polysaccharides, proteins, and synthetic polymers for wound dressing and skin scaffolding – A review DOI
Ali Sadeghianmaryan,

Nivad Ahmadian,

Sydney Wheatley

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 266, P. 131207 - 131207

Published: March 28, 2024

Language: Английский

Citations

26

Bringing innovative wound care polymer materials to the market: Challenges, developments, and new trends DOI
Pegah Sanjarnia, Matías L. Picchio,

Agustin N. Polegre Solis

et al.

Advanced Drug Delivery Reviews, Journal Year: 2024, Volume and Issue: 207, P. 115217 - 115217

Published: Feb. 27, 2024

Language: Английский

Citations

21

Advancements in Wound Dressing Materials: Highlighting Recent Progress in Hydrogels, Foams, and Antimicrobial Dressings DOI Creative Commons

A. S. Alberts,

Dana-Ionela Tudorache,

Adelina-Gabriela Niculescu

et al.

Gels, Journal Year: 2025, Volume and Issue: 11(2), P. 123 - 123

Published: Feb. 7, 2025

Recent advancements in wound dressing materials have significantly improved acute and chronic management by addressing challenges such as infection control, moisture balance, enhanced healing. Important progress has been made, especially with hydrogels, foams, antimicrobial for creating optimized dressings. Hydrogels are known maintaining optimal levels, while foam dressings excellent exudate absorbents. Meanwhile, incorporates various agents to reduce risks. These options healing time focusing on customized patient needs. Therefore, this review highlights the newest research prototypes applications, emphasizing their particular benefits clinical importance. Innovations stimuli-responsive hydrogels hybrid bioengineered composites discussed relation properties, including responsiveness pH, temperature, glucose, or enzymes drug delivery precision. Moreover, ongoing trials included, demonstrating potential of emerging solutions be soon translated from laboratory settings. By discussing interdisciplinary approaches that integrate advanced materials, nanotechnology, biological insights, work provides a contemporary framework patient-centric, efficient care strategies.

Language: Английский

Citations

7

New Perspectives of Hydrogels in Chronic Wound Management DOI Creative Commons

A. S. Alberts,

Ana‐Maria Bratu, Adelina-Gabriela Niculescu

et al.

Molecules, Journal Year: 2025, Volume and Issue: 30(3), P. 686 - 686

Published: Feb. 4, 2025

Chronic wounds pose a substantial healthcare concern due to their prevalence and cost burden. This paper presents detailed overview of chronic emphasizes the critical need for novel therapeutic solutions. The pathophysiology wound healing is discussed, including stages factors contributing chronicity. focus on diverse types wounds, such as diabetic foot necrosis, pressure ulcers, venous leg highlighting etiology, consequences, issues they provide. Further, modern care solutions, particularly hydrogels, are highlighted tackling challenges management. Hydrogels characterized multipurpose materials that possess vital characteristics like capacity retain moisture, biocompatibility, incorporation active drugs. Hydrogels’ effectiveness in applications demonstrated by how support healing, preserving ideal moisture levels, promoting cellular migration, possessing antibacterial properties. Thus, this hydrogel technology’s latest developments, emphasizing drug-loaded stimuli-responsive underscoring these advanced formulations greatly improve therapy outcomes enabling dynamic focused reactions environment. Future directions research promote development customized treatments digital health tools treatment wounds.

Language: Английский

Citations

5

Recent progresses of collagen dressings for chronic skin wound healing DOI Creative Commons

Shuangni Shi,

Lili Wang, Song Chen

et al.

Deleted Journal, Journal Year: 2023, Volume and Issue: 5(1)

Published: Oct. 23, 2023

Abstract The skin plays a fundamental role in regulating the body’s internal balance and protecting against external traumas. A broad variety of environmental risk factors frequently result acute wounds, whose inappropriate treatments would lead to chronic wounds that are difficult heal. Traditional dressings have been widely used repair however their drawbacks such as insufficient hemostatic efficacy non-moist environment severely limited clinical applications. As principal component skin, collagen has always research hotspot field due its advantages low antigenicity, high biocompatibility superior bioactivity. Collagen-based increasingly developed heal during past decades, arising from capability decreasing protein electrolyte losses wound exudate, preventing bacterial contamination, permitting less painful dressing changes, improving healing quality. This review overviews recent progress for healing. Various commonly management first introduced. Collagen categorized films, sponges, hydrogels, nanofibers, powders, compared. critical functions healing, stopping bleeding, shortening inflammation, promoting angiogenesis, stimulating tissue regeneration elaborated. applications different types thoroughly summarized. comprehensive list commercialized updated, an outlook finally speculated. Graphical

Language: Английский

Citations

30

Animal tissue-derived biomaterials for promoting wound healing DOI
Xinyue Cao, Xiang Lin, Ning Li

et al.

Materials Horizons, Journal Year: 2023, Volume and Issue: 10(9), P. 3237 - 3256

Published: Jan. 1, 2023

This work highlights the animal tissue-derived biomaterials in wound treatment field based on an evaluation of their critical properties, advanced design strategies and latest applications.

Language: Английский

Citations

28

Antibacterial Aloe vera Based Biocompatible Hydrogel for Use in Dermatological Applications DOI Open Access
Mariana Chelu, Adina Magdalena Musuc, Ludmila Aricov

et al.

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(4), P. 3893 - 3893

Published: Feb. 15, 2023

The present research aims to describe a new methodology obtain biocompatible hydrogels based on Aloe vera used for wound healing applications. properties of two (differing in concentration, AV5 and AV10) prepared by an all-green synthesis method from raw, natural, renewable bioavailable materials such as salicylic acid, allantoin xanthan gum were investigated. morphology the hydrogel biomaterials was studied SEM analysis. rheological hydrogels, well their cell viability, biocompatibility cytotoxicity, determined. antibacterial activity evaluated both Gram-positive, Staphylococcus aureus Gram-negative, Pseudomonas aeruginosa strains. obtained novel green showed good properties. In vitro scratch assay demonstrated capacity AV10 accelerate proliferation migration induce closure wounded area. A corroboration all morphological, rheological, cytocompatibility viability results indicates that this may be suitable

Language: Английский

Citations

27

Polymer-Based Functional Materials Loaded with Metal-Based Nanoparticles as Potential Scaffolds for the Management of Infected Wounds DOI Creative Commons
Xhamla Nqoro, Raymond Taziwa

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(2), P. 155 - 155

Published: Jan. 23, 2024

Wound infection due to bacterial invasion at the wound site is one of primary challenges associated with delayed healing. Microorganisms tend form biofilms that protect them from harm, leading their multidrug resistance. The alarming increase in antibiotic resistance poses a threat Hence, urgent need for novel dressing materials capable managing crucial expediting recovery. There considerable interest polymeric dressings embedded bioactive substances, such as metal-based nanoparticles, potential solutions treating microbially infected wounds. Metal-based nanoparticles have been widely used management wounds broad antimicrobial efficacy. This review focuses on polymer-based and loaded like silver, gold, magnesium oxide, or zinc oxide. When compared, oxide-loaded exhibited higher antibacterial activity against Gram-positive strains silver nanoparticle-loaded gram-negative strains. However, infused both displayed synergistic effect bacteria. Furthermore, these antibiofilm generation reactive oxygen species while accelerating closure vitro vivo.

Language: Английский

Citations

13

Recent advances in harnessing biological macromolecules for wound management: A review DOI

Jingxuan Yuan,

Shuo Wang, Jie Yang

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 266, P. 130989 - 130989

Published: March 18, 2024

Language: Английский

Citations

11

Diabetic wound healing potential of silk sericin protein based hydrogels enriched with plant extracts DOI

Samia Zahoor,

Hafiz Muhammad Tahir, Shaukat Ali

et al.

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 242, P. 125184 - 125184

Published: June 3, 2023

Language: Английский

Citations

19