Intelligent Internet of Medical Things for Depression: Current Advancements, Challenges, and Trends DOI Creative Commons
Md Belal Bin Heyat, Deepak Adhikari, Faijan Akhtar

et al.

International Journal of Intelligent Systems, Journal Year: 2025, Volume and Issue: 2025(1)

Published: Jan. 1, 2025

We investigated the fusion of Intelligent Internet Medical Things (IIoMT) with depression management, aiming to autonomously identify, monitor, and offer accurate advice without direct professional intervention. Addressing pivotal questions regarding IIoMT’s role in identification, its correlation stress anxiety, impact machine learning (ML) deep (DL) on depressive disorders, challenges potential prospects integrating management IIoMT, this research offers significant contributions. It integrates artificial intelligence (AI) (IoT) paradigms expand studies, highlighting data science modeling’s practical application for intelligent service delivery real‐world settings, emphasizing benefits within IoT. Furthermore, it outlines an IIoMT architecture gathering, analyzing, preempting employing advanced analytics enhance intelligence. The study also identifies current challenges, future trajectories, solutions domain, contributing scientific understanding management. evaluates 168 closely related articles from various databases, including Web Science (WoS) Google Scholar, after rejection repeated books. shows that there is 48% growth articles, mainly focusing symptoms, detection, classification. Similarly, most being conducted United States America, trend increasing other countries around globe. These results suggest essence automated monitoring, suggestions handling depression.

Language: Английский

Heart rate variability as a biomarker in health and affective disorders: A perspective on neuroimaging studies DOI

James Mulcahy,

Dennis E O Larsson, Sarah N. Garfinkel

et al.

NeuroImage, Journal Year: 2019, Volume and Issue: 202, P. 116072 - 116072

Published: Aug. 3, 2019

Language: Английский

Citations

125
Gut microbiome patterns depending on children’s psychosocial stress: Reports versus biomarkers DOI
Nathalie Michels, Tom Van de Wiele, Fiona Fouhy

et al.

Brain Behavior and Immunity, Journal Year: 2019, Volume and Issue: 80, P. 751 - 762

Published: May 18, 2019

Language: Английский

Citations

92
Psychological and biological resilience modulates the effects of stress on epigenetic aging DOI
Zachary M. Harvanek, Nia Fogelman, Ke Xu

et al.

Translational Psychiatry, Journal Year: 2021, Volume and Issue: 11(1)

Published: Nov. 27, 2021

Language: Английский

Citations

75
FK506 binding proteins and inflammation related signalling pathways; basic biology, current status and future prospects for pharmacological intervention DOI
Stephanie Annett, Gillian Moore, Tracy Robson

et al.

Pharmacology & Therapeutics, Journal Year: 2020, Volume and Issue: 215, P. 107623 - 107623

Published: July 2, 2020

Language: Английский

Citations

74
Strategies for Promotion of a Healthy Lifestyle in Clinical Settings: Pillars of Ideal Cardiovascular Health: A Science Advisory From the American Heart Association DOI Open Access
Penny M. Kris‐Etherton, Kristina H. Petersen, Jean‐Pierre Després

et al.

Circulation, Journal Year: 2021, Volume and Issue: 144(24)

Published: Oct. 25, 2021

Engagement in healthy lifestyle behaviors is suboptimal. The vast majority of the US population does not meet current recommendations. A defined by consuming a dietary pattern, engaging regular physical activity, avoiding exposure to tobacco products, habitually attaining adequate amounts sleep, and managing stress levels. For all these health there are well-established guidelines; however, promotion clinical settings can be challenging. It critical overcome challenges because greater heathy practices effectively motivates initiates patient behavior change. 5A Model (assess, advise, agree, assist, arrange) was developed provide framework for counseling with requisite attention demands settings. In this science advisory, we present strategies, based on Model, that clinicians other care professionals use efficient lifestyle-related change patients at levels cardiovascular disease risk every visit. addition, discuss underlying role psychological well-being counseling, how leverage technologies when providing brief patient-centered counseling. Greater during routine clinician visits will contribute promoting health.

Language: Английский

Citations

69
Pretreatment with Panaxatriol Saponin Attenuates Mitochondrial Apoptosis and Oxidative Stress to Facilitate Treatment of Myocardial Ischemia-Reperfusion Injury via the Regulation of Keap1/Nrf2 Activity DOI Open Access
Huan Yao, Qian Xie,

Qingman He

et al.

Oxidative Medicine and Cellular Longevity, Journal Year: 2022, Volume and Issue: 2022, P. 1 - 20

Published: May 27, 2022

Myocardial ischemia-reperfusion injury (MIRI) is a type of severe to the ischemic myocardium that can occur following recovery blood flow, and for which, there no effective treatment. Panaxatriol saponin (PTS), major active component P. notoginseng, has been used clinically treat ischemia-related encephalopathy due its antioxidant activity, but effect on cardiomyopathy underlying mechanism action still unclear. This study was performed investigate protective PTS against MIRI explore potential mechanisms. Hydrogen peroxide (H2O2) stimulate cardiomyocytes, mimic in vitro. Cell viability tested using CCK-8 method. The activity H9c2 rat cardiomyocyte cell line examined 2',7'-dichlorodihydrofluorescein diacetate (DCFH-DA). levels superoxide dismutase-1 (SOD1), SOD2, heme oxygenase (HO-1) were determined by Western blotting and/or immunofluorescence. antiapoptotic determined. In addition, mitochondrial permeability transition pore (mPTP) opening membrane (ΔΨm) changes assessed. Changes Keap1/Nrf2 activation evaluated analysis, molecular docking, immunoprecipitation. An vivo model established rats, myocardial infarct size measured 2,3,5-triphenyltetrazolium chloride (TTC) staining. enzyme activities ELISA or biochemical analyses. Furthermore, Nrf2 evaluated, regulatory apoptosis blocker, ML385. results showed ameliorated induced H2O2, characterized increased viability, decreased reactive oxygen species (ROS) production, promotion SOD1, HO1 expression. inhibited also reduced mPTP stabilized ΔΨm cells. Molecular docking immunoprecipitation revealed disrupt interaction directly blocking binding site Keap1 protein. vivo, area infarction attenuated pathological damage (I/R) rats. markers PTS. Finally, regulated nuclear translocation Nrf2, ML385 blocked therapeutic These suggested targeting activity.

Language: Английский

Citations

44
Dietary Inflammatory Index and Its Association with the Prevalence of Coronary Heart Disease among 45,306 US Adults DOI Open Access
Li‐Da Wu, Yi Shi, Chaohua Kong

et al.

Nutrients, Journal Year: 2022, Volume and Issue: 14(21), P. 4553 - 4553

Published: Oct. 28, 2022

Inflammation plays a pivotal in the occurrence and development of coronary heart disease (CHD). We aim to investigate association between Dietary Inflammatory Index (DII) CHD present study. In this cross-sectional study, adult participants from National Health Nutrition Examination Survey (NHANES) (1999–2018) were enrolled. The social demographic information, lifestyle factors, blood biochemical measurements, dietary status all systematically collected. Multivariable logistic regression was adopted risk DII. Besides, restricted cubic spline (RCS) analysis used explore whether there nonlinear DII CHD. Subgroup stratified by sex, age, race/ethnicity, BMI conducted evaluate among different populations. A total 45,306 adults NHANES included. Compared with individuals without CHD, DIIs significantly elevated. positive observed multivariable after adjusting for education levels, smoking, drinking, diabetes, hypertension, body mass index (BMI). Results RCS suggested relationship addition, increment had greater impact on female compared male individuals. is closely associated For better prevention treatment more attention should be paid controlling inflammation.

Language: Английский

Citations

44
Psychological Stress and Heart Disease: Fact or Folklore? DOI Creative Commons
Glenn N. Levine

The American Journal of Medicine, Journal Year: 2022, Volume and Issue: 135(6), P. 688 - 696

Published: March 9, 2022

Abstract

For at least a few centuries, if not millennia, psychological stress has been popularly believed to contribute heart disease. Does really disease? Are anecdotal, patient, and lay press reports that angina, attack, even cardiac death are caused by based on fact, or they just folklore? In this review, the study data supporting associations between cardiovascular risk, as well potential mechanisms which might disease precipitate myocardial ischemia infarction, critically reviewed summarized.

Language: Английский

Citations

43
The Impact of Mental Stress on Cardiovascular Health—Part II DOI Open Access
Michael Y. Henein,

Sergio Vancheri,

Giovanni Longo

et al.

Journal of Clinical Medicine, Journal Year: 2022, Volume and Issue: 11(15), P. 4405 - 4405

Published: July 28, 2022

Endothelial dysfunction is one of the earliest manifestations atherosclerosis, contributing to its development and progression. Mental stress induces endothelial through increased activity sympathetic nervous system, release corticotropin-releasing hormone from hypothalamus, inhibition nitric oxide (NO) synthesis by cortisol, levels pro-inflammatory cytokines. Mental-stress-induced output system concomitant withdrawal parasympathetic inflammatory reflex results in systemic inflammation activation a neural–hematopoietic–arterial axis. This includes brainstem subcortical regions network, bone marrow activation, leukocytes into circulation their migration arterial wall atherosclerotic plaques. Low-grade, sterile involved all steps atherogenesis, coronary plaque formation destabilisation rupture. Increased tone may cause smooth-muscle-cell proliferation, resulting vascular hypertrophy, thus hypertension. Emotional events also instability cardiac repolarisation due brain lateralised imbalance autonomic stimulation, which lead asymmetric arrhythmia. Acute emotional can provoke severe catecholamine release, leading direct myocyte injury calcium overload, known as myocytolysis, microvascular vasoconstriction, an increase left ventricular afterload. These changes trigger heart failure syndrome mimicking acute myocardial infarction, characterised transient apical ballooning, (Takotsubo) cardiomyopathy. Women are more prone than men develop mental-stress-induced ischemia (MSIMI), probably reflecting gender differences patterns during mental stress. Although guidelines on CV prevention recognise psychosocial factors risk modifiers improve prediction decision making, evidence that assessment treatment will prevent CAD needs further evaluation.

Language: Английский

Citations

40
Glucocorticoid regulation of cancer development and progression DOI Creative Commons
Stuti Khadka,

Sara R. Druffner,

Benjamin C. Duncan

et al.

Frontiers in Endocrinology, Journal Year: 2023, Volume and Issue: 14

Published: April 18, 2023

Glucocorticoids are steroid hormones that regulate a host of cellular and physiological functions. However, they arguably best known for their potent anti-inflammatory properties. Chronic inflammation is well-known to promote the development progression numerous types cancer, emerging evidence suggests glucocorticoid regulation affects cancer development. timing, intensity, duration signaling have important but often contradictory effects on Moreover, glucocorticoids widely used in parallel with radiation chemotherapy control pain, dyspnea, swelling, use may compromise anti-tumor immunity. This review will explore particular focus pro

Language: Английский

Citations

29