A Review of Nanotechnology in microRNA Detection and Drug Delivery DOI Creative Commons
Hsiuying Wang

Cells, Journal Year: 2024, Volume and Issue: 13(15), P. 1277 - 1277

Published: July 30, 2024

MicroRNAs (miRNAs) are small, non-coding RNAs that play a crucial role in regulating gene expression. Dysfunction miRNAs can lead to various diseases, including cancers, neurological disorders, and cardiovascular conditions. To date, approximately 2000 have been identified humans. These small molecules shown promise as disease biomarkers potential therapeutic targets. Therefore, identifying miRNA for diseases developing effective drug delivery systems essential. Nanotechnology offers promising new approaches addressing scientific medical challenges. Traditional detection methods include next-generation sequencing, microarrays, Northern blotting, reverse transcription-quantitative polymerase chain reaction (RT-qPCR). serve an alternative blotting RT-qPCR detection. Moreover, nanomaterials exhibit unique properties differ from larger counterparts, enabling therapeutics more effectively enter target cells, reduce degradation the bloodstream, be released specific tissues or cells. This paper reviews application of nanotechnology systems. Given still stages, holds great accelerating development.

Language: Английский

Conductive hydrogels for tissue repair DOI Creative Commons
Yongping Liang, Lipeng Qiao,

Bowen Qiao

et al.

Chemical Science, Journal Year: 2023, Volume and Issue: 14(12), P. 3091 - 3116

Published: Jan. 1, 2023

This work reviewed the new progress of conductive hydrogels in application tissue repair and provided a useful reference for further preparation safer more efficient engineering.

Language: Английский

Citations

81

Advances in Electrochemical Nano-Biosensors for Biomedical and Environmental Applications: From Current Work to Future Perspectives DOI Creative Commons
Rabeay Y. A. Hassan

Sensors, Journal Year: 2022, Volume and Issue: 22(19), P. 7539 - 7539

Published: Oct. 5, 2022

Modern life quality is strongly supported by the advances made in biosensors, which has been attributed to their crucial and viable contribution point-of-care (POC) technology developments. POC devices are exploited for fast tracing of disease progression, rapid analysis water, food assessment. Blood glucose meters, home pregnancy strips, COVID-19 tests all represent common examples successful biosensors. Biosensors can provide great specificity due incorporation selective bio-recognition elements portability at significantly reduced costs. Electrochemical biosensor platforms one most advantageous these because they offer many merits, such as being cheap, selective, specific, rapid, portable. Furthermore, be incorporated into smartphones various analytical approaches order increase sensitivity other properties. As a very broad interdisciplinary area research development, biosensors include disciplines backgrounds from materials science, chemistry, physics, medicine, microbiology/biology, engineering. Accordingly, this state-of-the-art article, historical background alongside long journey biosensing construction starting Clark oxygen electrode until reaching highly advanced wearable stretchable devices, discussed. Consequently, selected among miscellaneous applications nanobiosensors (such microbial detection, cancer diagnosis, toxicity analysis, quality-control assurance, point care, health prognosis) described. Eventually, future perspectives intelligent commercialization exploitation real-life that going machine learning artificial intelligence (AI) stated.

Language: Английский

Citations

78

Biogeneration of Valuable Nanomaterials from Agro-Wastes: A Comprehensive Review DOI Creative Commons
Pinku Chandra Nath,

Amiya Ojha,

Shubhankar Debnath

et al.

Agronomy, Journal Year: 2023, Volume and Issue: 13(2), P. 561 - 561

Published: Feb. 15, 2023

The exponential growth of agricultural output is a result the increasing world population. Agro-wastes are now acknowledged as an alternative material for manufacture renewable, inexpensive, and sustainable bio-composite-based products. Huge amounts produce often lost owing to lack processing facilities or storage space. Agriculture wastes contain significant concentration carbohydrates well various multifunctional groups organic substances, such polymeric proteins. Interestingly, nanotechnology provides better potential transform easily into valuable cost-effective products, removing need utilize noxious chemicals, which can create variety health environmental difficulties. Recently, there has been increase in interest eco-friendly nanomaterial (NM) production techniques that extracts generated from waste. Such nanoparticles (NPs) have extensively studied numerous uses, including antibacterial agents, water purification, breakdown industrial colours, many others. Consequently, purpose this review investigate different sources, characteristics, nano-management agro-waste; NMs derived their possible applications.

Language: Английский

Citations

52

A review of nanomaterials for biosensing applications DOI
Lei Li, Tianshu Wang, Yuting Zhong

et al.

Journal of Materials Chemistry B, Journal Year: 2023, Volume and Issue: 12(5), P. 1168 - 1193

Published: Dec. 21, 2023

A biosensor is a device that reacts with the analyte to be analyzed, detects its concentration, and generates readable information, which plays an important role in medical diagnosis, detection of physiological indicators, disease prevention. Nanomaterials have received increasing attention fabrication improvement biosensors due their unique physicochemical optical properties. In this paper, properties nanomaterials such as size effect, electrical properties, advantages field biosensing are briefly summarized, application can effectively improve sensitivity reduce limit biosensors. The commonly used gold nanoparticles (AuNPs), carbon nanotubes (CNTs), quantum dots (QDs), graphene, magnetic nanobeads for applications also reviewed. Besides, two main types using involved construction working principles described, toxicity biocompatibility future direction nanomaterial discussed.

Language: Английский

Citations

52

Carbon Nanomaterials for Biomedical Applications: Progress and Outlook DOI
Shweta J. Malode, Saravanan Pandiaraj, Abdullah N. Alodhayb

et al.

ACS Applied Bio Materials, Journal Year: 2024, Volume and Issue: 7(2), P. 752 - 777

Published: Jan. 25, 2024

Recent developments in nanoscale materials have found extensive use various fields, especially the biomedical industry. Several substantial obstacles must be overcome, particularly those related to nanostructured biomedicine, before they can used therapeutic applications. Significant concerns biomedicine include biological processes, adaptability, toxic effects, and nano-biointerfacial properties. Biomedical researchers difficulty choosing suitable for drug carriers, cancer treatment, antiviral uses. Carbon nanomaterials are among nanoparticle forms that continually receiving interest They owing their distinctive physical chemical properties, such as electrical, high-temperature, mechanical, optical diversification. An individualized, controlled, dependable, low-carcinogenic, target-specific delivery system diagnose treat infections The variety of carbon at is remarkable. Allotropes other same element, carbon, represented dimensions. These show promise a wide range with exceptional thermal properties graphene nanotubes. potentially revolutionize industries, including electronics, energy, medicine. Ongoing investigation expansion efforts continue unlock possibilities these materials, making them key player shaping future advanced technology. explore potential positive effects reducing greenhouse effect. current state sector covered this review, along synthesis techniques

Language: Английский

Citations

42

Electrochemical sensing mechanisms of neonicotinoid pesticides and recent progress in utilizing functional materials for electrochemical detection platforms DOI
Longhua Ding, Jiawei Guo, Shu Chen

et al.

Talanta, Journal Year: 2024, Volume and Issue: 273, P. 125937 - 125937

Published: March 16, 2024

Language: Английский

Citations

29

Carbon-based nanocomposites for biomedical applications DOI Creative Commons
Minkyu Shin, Joungpyo Lim,

Yongseon Park

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(10), P. 7142 - 7156

Published: Jan. 1, 2024

Carbon nanomaterials have attracted significant attention in the biomedical field, including for biosensing, drug delivery, and tissue engineering applications. Based on their inherent properties such as unique structure high conductivity, carbon can overcome current limitations research poor stability of biomolecules, low sensitivity selectivity biosensors, difficulty precise delivery. In addition, recently, several novel been integrated with to develop carbon-based nanocomposites application research. this review, we discuss recent studies First, representative composed other nanomaterials. Next, applications field are discussed according topics field. We engineering. conclusion, believe that review provides potential applicability suggests future directions

Language: Английский

Citations

25

Advancements in electrochemical glucose sensors DOI
Qing Huang, Jingqiu Chen, Yunong Zhao

et al.

Talanta, Journal Year: 2024, Volume and Issue: 281, P. 126897 - 126897

Published: Sept. 17, 2024

Language: Английский

Citations

23

Recent advances in gold nanoparticles-based biosensors for tuberculosis determination DOI
Reza Eivazzadeh‐Keihan, Zahra Saadatidizaji, Mohammad Mahdavi

et al.

Talanta, Journal Year: 2024, Volume and Issue: 275, P. 126099 - 126099

Published: April 12, 2024

Language: Английский

Citations

18

A dual-purpose electrode material for voltametric quantification of uric acid and supercapacitor performance using dysprosium-doped CaZrO3 DOI
Nandini Robin Nadar,

J. Deepak,

S.C. Sharma

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113081 - 113081

Published: Feb. 1, 2025

Language: Английский

Citations

2