Nutrition, Physical Activity, and Other Lifestyle Factors in the Prevention of Cognitive Decline and Dementia

Nutrients, Journal Year: 2021, Volume and Issue: 13(11), P. 4080 - 4080

Published: Nov. 15, 2021

Multiple factors combined are currently recognized as contributors to cognitive decline. The main independent risk factor for impairment and dementia is advanced age followed by other determinants such genetic, socioeconomic, environmental factors, including nutrition physical activity. In the next decades, a rise in cases expected due largely aging of world population. There no hitherto effective pharmaceutical therapies treat age-associated dementia, which underscores crucial role prevention. A relationship among diet, activity, lifestyle with function has been intensively studied mounting evidence supporting these development decline chief cause disability globally. Several dietary patterns, foods, nutrients have investigated this regard, some encouraging disappointing results. This review presents current effects components, supplements, sleep social engagement on prevention or delay onset age-related dementia.

Language: Английский

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Active Aging and Public Health: Evidence, Implications, and Opportunities

Annual Review of Public Health, Journal Year: 2021, Volume and Issue: 43(1), P. 439 - 459

Published: Dec. 15, 2021

By 2050, 20% of the world's population will be over age 65 years, with projections that 80% older adults living in low- to middle-income countries. Physical inactivity and sedentary time are particularly high adults, presenting unique public health challenges. In this article, we first review evidence points multiple beneficial outcomes active aging, including better physical function, cognitive mental health, social sleep, suggest need shift research focus from chronic disease more relevantoutcomes affect independence quality life. Second, critical role age-friendly environments facilitating aging equitably across different countries cultures. Finally, consider emerging opportunities related engagement technology-enabled mobility can facilitate aging. all these contexts, it is a priority understand address diversity within global population.

Language: Английский

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Cognitive Aging and the Promise of Physical Activity

Annual Review of Clinical Psychology, Journal Year: 2022, Volume and Issue: 18(1), P. 417 - 442

Published: Jan. 19, 2022

Is the field of cognitive aging irretrievably concerned with decline and deficits, or is it shifting to emphasize hope preservation enhancement function in late life? A fragment an answer comes from research attempting understand reasons for individual variability extent rate decline. This body work has created a sense optimism based on evidence that there are some health behaviors amplify performance mitigate age-related In this context, we discuss role physical activity neurocognitive adulthood summarize how can be conceptualized as constructive approach both maintenance therapeutic enhancing optimizing life. way, used shape perceptions aging.

Language: Английский

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Physical Activity Improves Cognition and Activities of Daily Living in Adults with Alzheimer’s Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(3), P. 1216 - 1216

Published: Jan. 22, 2022

Objective: The purpose of this meta-analysis was to examine the effects physical activity (PA) on cognition and activities daily living in adults with Alzheimer’s Disease (AD). Methods: Six electronic databases (MEDLINE, CINAHL, PsycArticles, SPORTDiscus, EMBASE CNKI) were used search for potential studies from inception until October 2021. Randomized controlled trials (RCTs) investigating effect AD patients compared a control condition included. sizes synthesized using random model 95% confidence interval (CI). Results: Sixteen articles including 945 participants (aged 70 88 years, 34.6% male) met inclusion criteria. pooled demonstrated that PA intervention associated significant improvements global (Standard Mean Difference (SMD) = 0.41, CI [0.24, 0.58], p < 0.01) (SMD 0.56, [0.32, 0.79], patients. Subgroup analyses suggested 3–4 times per week 30–45 min more than 12 weeks had relatively strong improving sensitivity analysis showed robust results. Conclusions: findings current can improve their Activities Daily Living (ADL) through engaging aerobic mixed exercise (aerobic anaerobic exercise).

Language: Английский

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Physical activity and exercise for the prevention and management of mild cognitive impairment and dementia: a collaborative international guideline

European Geriatric Medicine, Journal Year: 2023, Volume and Issue: 14(5), P. 925 - 952

Published: Sept. 28, 2023

Physical activity and exercise have been suggested as effective interventions for the prevention management of mild cognitive impairment (MCI) dementia, but there are no international guidelines.

Language: Английский

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Effects of physical activity and exercise interventions on Alzheimer’s disease: an umbrella review of existing meta-analyses

Journal of Neurology, Journal Year: 2022, Volume and Issue: 270(2), P. 711 - 725

Published: Nov. 7, 2022

Language: Английский

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The Cause of Alzheimer’s Disease: The Theory of Multipathology Convergence to Chronic Neuronal Stress

Aging and Disease, Journal Year: 2022, Volume and Issue: 13(1), P. 37 - 37

Published: Jan. 1, 2022

The field of Alzheimer's disease (AD) research critically lacks an all-inclusive etiology theory that would integrate existing hypotheses and explain the heterogeneity trajectory pathologies observed in each individual patient. Here, we propose a novel comprehensive named: multipathology convergence to chronic neuronal stress. Our new reconsiders long-standing dogmas advanced by previous incomplete theories. Firstly, while it is undeniable amyloid beta (Aβ) involved AD, seminal stage Aβ unlikely pathogenic. Instead, hypothesize root cause AD stress central nervous system (CNS), expressed as part physiological response protect CNS neurons from If there no return homeostasis, then becomes overexpressed, this includes generation longer forms are more toxic prone oligomerization. Secondly, plausibly not strictly compartmentalized within but may also result dysfunction other systems entire body. This view implies have single cause, rather needs be considered spectrum multiple pathological modalities converging persistent stressing neurons. These modalities, which include cardiovascular disease, metabolic disorders, structural changes, often start individually, over time combine with incrementally escalate amount applied We present case for considering marker hypoxic, toxic, starvation events, than solely AD. detail numerous human conditions can lead CNS, making link co-morbidities encountered daily clinical practice. Finally, how our could leveraged improve care related dementia personalized medicine paradigms near future.

Language: Английский

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Effects of exercise training on the cognitive function of older adults with different types of dementia: a systematic review and meta-analysis

British Journal of Sports Medicine, Journal Year: 2022, Volume and Issue: 56(16), P. 933 - 940

Published: May 16, 2022

Objectives To assess the effect of exercise training on cognitive function older adults living with different types dementia, as well potential moderators efficacy. Design Systematic review and meta-analysis. Data sources Cochrane Central, PsycINFO, Embase, Medline CINAHL. Eligibility criteria Peer-reviewed, randomised controlled trials, in English (1990–present), which examined effects dementia. Study appraisal synthesis Risk bias study quality were assessed (Cochrane Bias Tool 2.0 Physiotherapy Evidence Database Scale). We performed random-effects models using robust variance estimation tested approximate Hotelling-Zhang test. Results Twenty-eight studies (n=2158) included qualitative 25 For all-cause a small was observed ( g =0.19; 95% CI 0.05 to 0.33; p=0.009). Type dementia characteristics did not moderate (p>0.05). Adherence intervention moderated outcome size such that greater mean adherence associated sizes b =0.02; SE =0.01; p=0.005). Conclusion Exercise showed benefits for More research standardised reporting can strengthen evidence what works best PROSPERO registration number CRD42020198716.

Language: Английский

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Thirty years of research on physical activity, mental health, and wellbeing: A scientometric analysis of hotspots and trends

Frontiers in Public Health, Journal Year: 2022, Volume and Issue: 10

Published: Aug. 9, 2022

The sheer volume of research publications on physical activity, mental health, and wellbeing is overwhelming. aim this study was to perform a broad-ranging scientometric analysis evaluate key themes trends over the past decades, informing future lines research. We searched Web Science Core Collection from inception until December 7, 2021, using appropriate search terms such as “physical activity” or “mental health,” with no limitation language time. Eligible studies were articles, reviews, editorial material, proceeding papers. retrieved 55,353 documents published between 1905 2021. annual scientific production exponential mean growth rate 6.8% since 1989. 1988–2021 co-cited reference network identified 50 distinct clusters that presented significant modularity silhouette scores indicating highly credible ( Q = 0.848, S 0.939). This 6 major namely cardiovascular diseases, somatic disorders, cognitive decline/dementia, illness, athletes' performance, related health issues, eating COVID-19 pandemic. A focus latest found greenness/urbanicity (2014), concussion/chronic traumatic encephalopathy (2015), (2019) most active USA central, Chinese network, although important in size, relatively isolated. Our results strengthen expand central role activity public calling for systematic involvement professionals stakeholders decision-making process.

Language: Английский

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Preventive Strategies for Cognitive Decline and Dementia: Benefits of Aerobic Physical Activity, Especially Open-Skill Exercise

Brain Sciences, Journal Year: 2023, Volume and Issue: 13(3), P. 521 - 521

Published: March 21, 2023

As there is no curative treatment for dementia, including Alzheimer’s disease (AD), it important to establish an optimal nonpharmaceutical preventive intervention. Physical inactivity a representative modifiable risk factor especially AD in later life (>65 years). physical activity and exercise are inexpensive easy initiate, they may represent effective intervention the maintenance of cognitive function. Several studies have reported that interventions preventing decline dementia. This review outlines effects exercise-associated older adults with without impairment subsequently summarizes their possible mechanisms. Furthermore, this describes differences between two types exercise—open-skill (OSE) closed-skill (CSE)—in terms on Aerobic particularly useful OSE exerting stronger protective effect functions than CSE. Therefore, need actively promote worldwide emphasized.

Language: Английский

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