Nanotechnology and Precision Engineering,
Journal Year:
2023,
Volume and Issue:
7(1)
Published: Nov. 15, 2023
As
a
promising
cancer
treatment
method,
cold
atmospheric
plasma
has
received
widespread
attention
in
recent
years.
However,
previous
research
focused
more
on
how
to
realize
and
expand
the
anti-cancer
scope
of
jet.
There
are
also
studies
killing
small-scale
cells,
but
effects
jet
normal
cells
cell
clusters
have
been
ignored.
Therefore,
we
proposed
50
µm
sized
micro-plasma
device,
used
device
treat
melanoma
(A-375)
human
glial
(HA1800)
evaluate
their
cells.
The
experimental
results
show
that
this
kind
can
effectively
inactivate
short
period
time,
while
having
little
effect
This
work
provides
certain
basis
for
application
fine
clinically
Aggregate,
Journal Year:
2022,
Volume and Issue:
4(2)
Published: Oct. 3, 2022
Abstract
Digital
light
processing
(DLP)‐based
bioprinting
technology
has
recently
aroused
considerable
concerns
as
a
strategy
to
deliver
biomedical
materials
and/or
specific
cells
create
sophisticated
structures
for
various
tissue
modeling
and
regeneration.
In
this
review,
we
display
concise
introduction
of
DLP
bioprinting,
further
discussion
on
the
design
manufacture
(bio)printer
with
varied
bioinks
their
applications
toward
drug
screening,
disease
modeling,
repair,
regenerative
medicine.
Finally,
advantages,
challenges,
perspectives
printing
platforms
are
detailed.
It
is
believed
that
will
play
decisive
role
in
field
model
medicine,
mainly
due
its
time‐efficient,
higher
resolution,
amenability
automation
needs.
Biomaterials Science,
Journal Year:
2024,
Volume and Issue:
12(8), P. 1950 - 1964
Published: Jan. 1, 2024
This
review
introduces
different
methods
used
to
generate
microgels
and
the
microgel-based
bioink
for
bioprinting.
Besides,
further
tendency
of
microgel
development
in
future
is
predicted.
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2022,
Volume and Issue:
10
Published: Feb. 16, 2022
Increasing
population
is
suffering
from
neurological
disorders
nowadays,
with
no
effective
therapy
available
to
treat
them.
Explicit
knowledge
of
network
neurons
(NoN)
in
the
human
brain
key
understanding
pathology
diseases.
Research
NoN
developed
slower
than
expected
due
complexity
and
ethical
considerations
for
vivo
studies.
However,
advances
nanomaterials
micro-/nano-microfabrication
have
opened
up
chances
a
deeper
ex
,
one
step
closer
This
review
therefore
summarizes
latest
lab-on-chip
microsystems
studies
by
focusing
on
advanced
materials,
techniques,
models
The
essential
methods
constructing
are
microfluidics
microelectrode
arrays.
Through
combination
functional
biomaterials
biocompatible
arrays
enable
development
various
also
includes
state-of-the-art
slide
organoid-on-chip
models.
end
this
discusses
previous
issues
future
perspectives
Translational Oncology,
Journal Year:
2023,
Volume and Issue:
37, P. 101750 - 101750
Published: Aug. 10, 2023
Cancerous
tumors
are
among
the
most
fatal
diseases
worldwide,
claiming
nearly
10
million
lives
in
2020.
Due
to
their
complex
and
dynamic
nature,
modeling
accurately
is
a
challenging
task.
Current
models
suffer
from
inadequate
translation
between
vitro
vivo
results,
primarily
due
isotropic
nature
of
microenvironment's
relationship.
To
address
these
limitations,
hydrogel-based
3D
bioprinting
emerging
as
promising
approach
mimic
cancer
development
behavior.
It
provides
precise
control
over
individual
elements'
size
distribution
within
microenvironment
enables
use
patient-derived
tumor
cells,
rather
than
commercial
lines.
Consequently,
hydrogel
expected
become
state-of-the-art
technique
for
research.
This
manuscript
presents
an
overview
statistics,
current
methods,
limitations.
Additionally,
we
highlight
significance
bioprinting,
its
applications
modeling,
importance
selection.
We
further
explore
state
creating
five
deadliest
cancers
using
bioprinting.
Finally,
discuss
trends
future
perspectives
on
clinical
Advanced Materials Technologies,
Journal Year:
2022,
Volume and Issue:
8(4)
Published: Oct. 30, 2022
Abstract
Porous
GelMA
microgels
are
promising
scaffolds
for
biomedical
research
and
regenerative
medicine
due
to
their
special
topology,
cell‐loading
capacity,
high
biocompatibility.
However,
the
traditional
preparation
of
porous
is
often
limited
by
some
complex
postprocessing
processes
such
as
freeze‐drying
swelling
equilibrium.
Herein,
we
present
a
simple
strategy
in
situ
generation
cell
carriers
integrating
placeholder
polyethylene
oxide
(PEO)
chaotic
advection
effect
droplets
microfluidic
devices.
The
device
mainly
composed
four
functional
units,
including
droplet
generation,
rapid
mixing,
photopolymerization,
collection.
allows
precise
control
size
porosity
changing
flow
rates
continuous
dispersed
phases.
Furthermore,
both
human
mesenchymal
stem
cells
(hMSCs)
umbilical
vein
endothelial
(HUVECs)
cultured
on
surface
obtained
show
viability,
spreading,
proliferation,
which
indicate
good
biocompatibility
potential
microcarriers
various
types.
proposed
provides
novel
approach
holding
promise
tissue
engineering
scalable
expansion.
Materials & Design,
Journal Year:
2022,
Volume and Issue:
223, P. 111152 - 111152
Published: Sept. 13, 2022
Bioprinting
of
cell-laden
hydrogel
constructs
providing
three-dimensional
(3D)
spatial
pattern
capacity
and
suitable
cellular
microenvironment
have
become
essential
tools
in
the
field
tissue
engineering.
For
heterogeneous
development,
printing
approaches
permitting
controllable
deposition
multicellular
components
a
flexible
manner
are
urgently
needed.
Here,
facile
dot-extrusion
(DEP)
system
for
one-step
generation
gelatin
methacrylate
(GelMa)
beads
(GHBs)
is
developed,
which
allows
size-tunable
GHBs
programmable
positioned
into
complex
3D
constructs.
The
GelMa
situ
semi-gelled
at
printhead,
thus
enabling
onto
platform,
as
result
improved
simplicity,
fidelity
flexibility.
size
position
adjustable
by
programming
G-code
parameters.
Further,
integrating
multiple
printheads,
encapsulating
different
can
be
printed
to
fabricate
constructs,
maintain
post-printed
cell
viability
over
95%.
As
an
example
application,
two
tumor-stroma
phases
were
developed
through
regionally
tumor
cells
normal
fibroblasts
juxtapositional
or
overlapping
microcapsule
structures,
giving
access
study
interactions
microenvironments.
DEP
holds
promise
creation
tissues
toward
various
biology
studies.
Current Issues in Molecular Biology,
Journal Year:
2023,
Volume and Issue:
45(2), P. 1100 - 1112
Published: Jan. 30, 2023
Cell
culture
is
an
important
tool
in
biological
research.
Most
studies
use
2D
cell
culture,
but
cells
grown
have
drawbacks,
including
limited
and
cell-extracellular
matrix
interactions,
which
make
it
inaccurate
to
model
conditions
vivo.
Anticancer
drug
screening
research
development
process
for
developing
new
drugs.
As
experiment
mimic
the
cancer
environment
vivo,
several
been
carried
out
on
3-dimensional
(3D)
cultures
with
added
biomaterials.
The
of
hydrogel
3D
currently
developing.
type
used
might
influence
morphology,
viability,
outcome.
Therefore,
this
review
discusses
regarding
addition
