Journal of Nanomaterials,
Journal Year:
2024,
Volume and Issue:
2024, P. 1 - 23
Published: Jan. 8, 2024
Chronic
wounds,
which
include
venous
leg
ulcers,
diabetic
foot
and
pressure
are
a
global
health
issue
that
affects
between
1%
2%
of
the
developed
world’s
population.
wound
healing
necessitates
extensive
medical
intervention
at
costly
healthcare
expenses.
Wound
care
management
is
mainly
dependent
on
discovery
new
appropriate
chronic
dressing
materials,
it
remains
focus
research
in
care.
Biocompatible
metallic
nanoparticle-loaded
offers
novel
opportunity
for
effectively
overcoming
inherent
drawbacks
traditional
particularly
nonhealing
wounds
due
to
their
clinical
complexity,
example,
infections,
irritation,
trauma,
persistence
foreign
body
or
bacterial
proteins,
ischemia.
In
this
review,
we
will
primarily
advancements
nanoparticle-based
antibacterial
antioxidant
materials
(e.g.,
hydrogels,
electrospun
scaffolds,
sponges,
films)
treatment
overcome
limitations
dressings.
ACS Biomaterials Science & Engineering,
Journal Year:
2024,
Volume and Issue:
10(5), P. 2703 - 2724
Published: April 22, 2024
The
scientific
world
is
increasingly
focusing
on
rare
earth
metal
oxide
nanomaterials
due
to
their
consequential
biological
prospects,
navigated
by
breakthroughs
in
biomedical
applications.
Terbium
belongs
elements
(lanthanide
series)
and
possesses
remarkably
strong
luminescence
at
lower
energy
emission
signal
transduction
properties,
ushering
wide
applications
for
diagnostic
measurements
(i.e.,
bioimaging,
biosensors,
fluorescence
imaging,
etc.)
the
sectors.
In
addition,
theranostic
of
terbium-based
nanoparticles
further
permit
targeted
delivery
drugs
specific
site
disease.
Furthermore,
antimicrobial
properties
terbium
induced
via
reactive
oxygen
species
(ROS)
cause
oxidative
damage
cell
membrane
nuclei
living
organisms,
ion
release,
surface
charge
interaction,
thus
creating
or
exhibiting
excellent
antioxidant
characteristics.
Moreover,
recent
tissue
engineering,
wound
healing,
anticancer
activity,
etc.,
angiogenesis,
proliferation,
promotion
growth
factors,
biocompatibility,
cytotoxicity
mitigation,
anti-inflammatory
potentials,
make
this
nanoparticle
anticipate
a
future
epoch
nanomaterials.
stand
as
game
changer
realm
research,
proffering
array
possibilities,
from
revolutionary
imaging
techniques
advanced
drug
systems.
Their
unique
including
luminescence,
magnetic
characteristics,
have
redefined
boundaries
what
can
be
achieved
biomedicine.
This
review
primarily
delves
into
various
mechanisms
involved
physicochemical
article
explains
potential
with
in-depth
significant
individual
literature.
additionally
stands
first
instance
furnish
"single-platted"
comprehensive
acquaintance
shaping
healthcare
well
limitations
overcoming
strategies
that
require
exploration
before
being
trialed
clinical
settings.
ACS Nano,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 17, 2025
Since
their
inception
in
the
early
1960s,
development
and
use
of
nanoscale
materials
have
progressed
tremendously,
roles
diverse
fields
ranging
from
human
health
to
energy
electronics
are
undeniable.
The
application
nanotechnology
inventions
has
revolutionized
many
aspects
everyday
life
including
various
medical
applications
specifically
drug
delivery
systems,
maximizing
therapeutic
efficacy
contained
drugs
by
means
bioavailability
enhancement
or
minimization
adverse
effects.
In
this
review,
we
utilize
CAS
Content
Collection,
a
vast
repository
scientific
information
extracted
journal
patent
publications,
analyze
trends
nanoscience
research
relevant
an
effort
provide
comprehensive
detailed
picture
field.
We
examine
publication
landscape
area
insights
into
current
knowledge
advances
developments.
review
major
classes
nanosized
routes,
targeted
diseases.
outline
most
discussed
concepts
assess
advantages
nanocarriers.
objective
is
broad
overview
evolving
regarding
challenges,
evaluate
growth
opportunities.
merit
stems
extensive,
wide-ranging
coverage
up-to-date
information,
allowing
unmatched
breadth
analysis
in-depth
insights.
Saudi Pharmaceutical Journal,
Journal Year:
2023,
Volume and Issue:
31(3), P. 462 - 471
Published: Feb. 1, 2023
The
intricate
process
of
wound
healing
involves
replacing
the
cellular
or
tissue
structure
that
has
been
destroyed.
In
recent
years
various
dressings
were
launched
but
reported
several
limitations.
topical
gel
preparations
are
intended
for
certain
skin
conditions
local
action.
Chitosan-based
hemostatic
materials
most
effective
in
halting
acute
hemorrhage,
and
naturally
occurring
silk
fibroin
is
widely
utilized
regeneration.
So,
this
study
was
conducted
to
evaluate
potential
chitosan
hydrogel(CHI-HYD)
hydrogel
(CHI-SF-HYD)
on
blood
clotting
healing.Hydrogel
prepared
using
concentrations
with
guar
gum
as
a
gelling
agent.
optimized
formulations
evaluated
visual
appearance,
Fourier
transforms
infrared
spectroscopy
(FT-IR),
pH,
spreadability,
viscosity,
antimicrobial
activity,
HR-TEM
analysis,
ex
vivo
permeation,
irritation,
stability
studies,
studies
by
adult
male
Wistar
albino
rats.Based
outcome
FT-IR,
no
chemical
interaction
between
components
noticed.
developed
hydrogels
exhibited
viscosity
79.2
±
4.2
Pa.s
(CHI-HYD),
79.8
3.8
(CHI-SF-HYD),
pH
5.87
0.2
5.96
0.1
(CHI-SF-HYD).
sterile
non-irritant
skin.
outcomes
show
CHI-SF-HYD
treated
group
significantly
shortened
span
reformation
than
other
groups.
This
demonstrated
could
consequently
accelerate
regeneration
damaged
area.Overall,
positive
revealed
improved
coagulation
re-epithelialization.
indicates
be
used
develop
novel
wound-healing
devices.
Advanced Functional Materials,
Journal Year:
2023,
Volume and Issue:
34(7)
Published: Oct. 31, 2023
Abstract
Nanosponges
are
unique
sponge‐like
carrier
systems
with
numerous
cavities
and
a
mesh‐like
network
throughout
their
surface.
They
categorized
into
three
types
based
on
the
material
of
construction,
i.e.,
polymer‐,
inorganic‐,
bio‐derived
material‐based
nanosponges.
Unlike
conventional
nanoparticles,
nanosponges
bear
countless
interconnected
voids
that
enables
maximum
drug,
imaging
probe,
or
photosensitizer
loading
via
absorption,
encapsulation,
conjugation,
complexion.
The
can
be
further
sealed
using
suitable
lipids
polymers
to
avoid
leakage
drugs
at
non‐target
site,
protect
therapeutics
from
biological
conditions,
control
release
for
prolonged
period.
Recently,
have
grasped
attention
researchers
in
area
cancer
by
overcoming
drawbacks
associated
delivery
immunotherapeutic,
targeted
therapeutic,
chemotherapeutic
agents.
Interestingly,
several
reports
also
witnessed
potential
theranostics.
Owing
this
supremacy,
could
an
apt
platform
therapy
diagnosis.
current
review
discusses
general
aspects,
types,
preparation
methods
In
addition,
ambit
treating
different
is
meticulously
discussed,
along
detailed
descriptions
corresponding
patents.
Furthermore,
role
phototherapy
theranostics
selectively
canvassed.
Materials Today Chemistry,
Journal Year:
2024,
Volume and Issue:
39, P. 102178 - 102178
Published: July 1, 2024
Inflammatory
arthritis
is
a
growing
worldwide
concern,
afflicting
millions
of
individuals
and
leading
to
depreciating
quality
life,
significant
morbidity,
subsequent
healthcare
burden.
Conventional
therapies
for
inflammatory
often
hold
limitations,
including
systemic
cross-reactivities,
side
effects,
inadequate
management
inflammation.
Therefore,
"Smart"
stimuli-responsive
biomaterials
are
materialized
as
promising
theranostic
approaches
management.
These
designed
specific
external
internal
stimulation,
enabling
the
sustained
release
bioactive
therapeutic
agents
during
local
or
administration.
Stimuli-responsive
allow
precise
spatiotemporal
control
over
drug
release,
minimizing
exposure,
reducing
off-target
real-time
monitoring
pathological
conditions,
driving
potential
breakthrough
in
managing
arthritis.
Owing
this
prominence,
review
article
expounds
on
emerging
prospects
targeting
molecular
signatures
associated
with
intricately
elicit
minimal
no
contradictory
effects.
In
addition,
application
these
disease
progression
multi-stimuli-responsive
comprehended
show
progress
diagnosis
treatment.
This
"single-platted"
comprehensive
acquaintance
clinical-based
outcomes
navigates
microenvironment,
proposing
an
optimistic
avenue
personalized
effective
minimized
