Nanotechnology based delivery of nutraceuticals DOI Creative Commons
Shailendra Gurav, Sameer Nadaf, Goutam Kumar Jena

et al.

Elsevier eBooks, Journal Year: 2023, Volume and Issue: unknown, P. 1 - 34

Published: Jan. 1, 2023

Language: Английский

Biogenic synthesis of zinc oxide nanoparticles using mushroom fungus Cordyceps militaris: Characterization and mechanistic insights of therapeutic investigation DOI

Charmaine Dias,

Muniappan Ayyanar, Singamoorthy Amalraj

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2022, Volume and Issue: 73, P. 103444 - 103444

Published: May 23, 2022

Language: Английский

Citations

55
Nanosponges for Drug Delivery and Cancer Therapy: Recent Advances DOI Creative Commons
Siavash Iravani, Rajender S. Varma

Nanomaterials, Journal Year: 2022, Volume and Issue: 12(14), P. 2440 - 2440

Published: July 16, 2022

Nanosponges with three-dimensional (3D) porous structures, narrow size distribution, and high entrapment efficiency are widely engineered for cancer therapy drug delivery purposes. They protect the molecular agents from degradation help to improve solubility of lipophilic therapeutic agents/drugs targeted options in addition being magnetized attain suitable magnetic features. Nanosponge-based systems have been applied specificity, biocompatibility, degradability, prolonged release behavior. In this context, loading within nanosponges is influenced by crystallization degree. Notably, 3D printing technologies can be development novel nanosponge-based biomedical applications. The impacts polymers, cross-linkers, type drugs, temperature, mechanism release, fabrication methods, substitution degree ought analytically evaluated. Eco-friendly techniques manufacturing still need uncovered existing such as solvent techniques, ultrasound-assisted preparation, melting strategies, emulsion diffusion methods. Herein, recent advancements associated potential (chiefly, cyclodextrin-based, DNAzyme, ethylcellulose nanosponges) deliberated, focusing on important challenges future perspectives.

Language: Английский

Citations

53
Eco synthesized chitosan/zinc oxide nanocomposites as the next generation of nano-delivery for antibacterial, antioxidant, antidiabetic potential, and chronic wound repair DOI

Diksha Halarnekar,

Muniappan Ayyanar,

Peramaiyan Gangapriya

et al.

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 242, P. 124764 - 124764

Published: May 5, 2023

Language: Английский

Citations

39
Revolutionizing the biomedical and environmental clean-up through polymeric nano-sponges: A review DOI
Ashwini Kumar, Popat Mohite, Shubham Munde

et al.

Nano-Structures & Nano-Objects, Journal Year: 2024, Volume and Issue: 39, P. 101193 - 101193

Published: June 10, 2024

Language: Английский

Citations

10
Fabrication of chitosan nanocomposites loaded with biosynthetic metallic nanoparticles and their therapeutic investigation DOI

Slavika Gracias,

Muniappan Ayyanar,

Gangapriya Peramaiyan

et al.

Environmental Research, Journal Year: 2023, Volume and Issue: 234, P. 116609 - 116609

Published: July 10, 2023

Language: Английский

Citations

21
Nanosponge: A promising and intriguing strategy in medical and pharmaceutical Science DOI Creative Commons
Akash Garg, Wen‐Cheng Lai, Himansu Chopra

et al.

Heliyon, Journal Year: 2023, Volume and Issue: 10(1), P. e23303 - e23303

Published: Dec. 6, 2023

The complicated chemical reactions involved in the production of newer drug delivery systems have mainly impeded efforts to build successful targeted for a prolonged duration time. Nanosponges, recently created colloidal system, potential overcome issues with medication toxicity, decreased bioavailability, and release over wide area because they can be modified work both hydrophilic hydrophobic types drugs. Nanosponges are small sized three-dimensional network having porous cavity. They prepared easily by crosslinking cyclodextrins different compounds. Due Cyclodextrin's outstanding biocompatibility, stability, safety, number Cyclodextrin-based been developed promptly. nanosponge system possesses various applications ailments such as cancer, autoimmune diseases, theranostic applications, enhanced etc. This review elaborates on benefits drawbacks, preparation techniques, factors affecting their preparation, characterization most current developments nanosponges.

Language: Английский

Citations

21
QbD-guided phospholipid-tagged nanonized boswellic acid naturosomal delivery for effective rheumatoid arthritis treatment DOI Creative Commons

Poonam Usapkar,

Suprit D. Saoji,

Pradnya Jagtap

et al.

International Journal of Pharmaceutics X, Journal Year: 2024, Volume and Issue: 7, P. 100257 - 100257

Published: May 19, 2024

Studies have reported the potential role of Boswellic acids (BAs), bioactive pentacyclic triterpenes from Boswellia serrata, in treating rheumatoid arthritis (RA). However, poor water solubility and limited oral absorption are restricting factors for its better therapeutic efficacy. Based on these assumptions, current study set out to develop naturosomal delivery BAs boost their extremely low bioavailability, colloidal stability, solubility. Nanonized naturosomes were developed subsequently analyzed show physicochemical functional features employing quality-by-design approach. The analysis acid (BSENs) revealed a 16 times improvement aqueous compared BS extract (BSE). zeta dynamic light scattering findings BSENs demonstrated stability with regulated nano-size particles. Additionally, BSE (⁓31%), in-vitro dissolution experiments showed that >99% released BSENs. ex-vivo permeation BSENs' (>79%) significantly improved over BSE's (⁓20%). In-vivo efficacy studies using CFA-prompted rodents critical expansion body wt an undeniable reduction paw thickness, volume, TNF-α treated BSEN control BSE-treated group. These suggest can help treat RA drugs by demonstrating further clinical research validate significant improvements.

Language: Английский

Citations

7
Endophytic fungi-assisted biomass synthesis of eco-friendly formulated silver nanoparticles for enhanced antibacterial, antioxidant, and antidiabetic activities DOI

Frazer Andrade,

Christopher Jenipher, Nilambari Gurav

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 97, P. 105749 - 105749

Published: May 6, 2024

Language: Английский

Citations

6
Design and optimization of chitosan-coated solid lipid nanoparticles containing insulin for improved intestinal permeability using piperine DOI

Indu Raghunath,

Marina Koland,

C. Sarathchandran

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 135849 - 135849

Published: Sept. 1, 2024

Language: Английский

Citations

6
Pteroyl-γ-l-glutamate/Pluronic® F68 modified polymeric micelles loaded with docetaxel for targeted delivery and reduced toxicity DOI
Nilesh Rarokar, Roshani Agrawal Khatry, Sakshi Yadav

et al.

Journal of Molecular Liquids, Journal Year: 2022, Volume and Issue: 369, P. 120842 - 120842

Published: Nov. 24, 2022

Language: Английский

Citations

25