Plant-Based Diets and Phytochemicals in the Management of Diabetes Mellitus and Prevention of Its Complications: A Review DOI Open Access
Prawej Ansari, Joyeeta T. Khan,

Suraiya Chowdhury

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(21), P. 3709 - 3709

Published: Oct. 30, 2024

Diabetes mellitus (DM) is currently regarded as a global public health crisis for which lifelong treatment with conventional drugs presents limitations in terms of side effects, accessibility, and cost. Type 2 diabetes (T2DM), usually associated obesity, characterized by elevated blood glucose levels, hyperlipidemia, chronic inflammation, impaired β-cell function, insulin resistance. If left untreated or when poorly controlled, DM increases the risk vascular complications such hypertension, nephropathy, neuropathy, retinopathy, can be severely debilitating life-threatening. Plant-based foods represent promising natural approach management T2DM due to vast array phytochemicals they contain. Numerous epidemiological studies have highlighted importance diet rich plant-based (vegetables, fruits, spices, condiments) prevention DM. Unlike medications, products are widely accessible, affordable, generally free from adverse effects. Integrating plant-derived into daily not only helps control hyperglycemia observed but also supports weight obese individuals has broad benefits. In this review, we provide an overview pathogenesis current therapeutic DM, particular focus on potential foods.

Language: Английский

Nutritional Composition and Bioactive Compounds in Tomatoes and Their Impact on Human Health and Disease: A Review DOI Creative Commons
Md. Yousuf Ali, Abu Ali Ibn Sina, Shahad Saif Khandker

et al.

Foods, Journal Year: 2020, Volume and Issue: 10(1), P. 45 - 45

Published: Dec. 26, 2020

Tomatoes are consumed worldwide as fresh vegetables because of their high contents essential nutrients and antioxidant-rich phytochemicals. contain minerals, vitamins, proteins, amino acids (leucine, threonine, valine, histidine, lysine, arginine), monounsaturated fatty (linoleic linolenic acids), carotenoids (lycopene β-carotenoids) phytosterols (β-sitosterol, campesterol stigmasterol). Lycopene is the main dietary carotenoid in tomato tomato-based food products lycopene consumption by humans has been reported to protect against cancer, cardiovascular diseases, cognitive function osteoporosis. Among phenolic compounds present tomato, quercetin, kaempferol, naringenin, caffeic acid lutein most common. Many these have antioxidant activities effective protecting human body various oxidative stress-related diseases. Dietary tomatoes increase body's level antioxidants, trapping reactive oxygen species reducing damage important biomolecules such membrane lipids, enzymatic proteins DNA, thereby ameliorating stress. We reviewed nutritional phytochemical compositions tomatoes. In addition, impacts constituents on health, particularly some degenerative also discussed.

Language: Английский

Citations

332

Lycopene as a Natural Antioxidant Used to Prevent Human Health Disorders DOI Creative Commons
Muhammad Imran, Fereshteh Ghorat,

Iahtisham Ul-Haq

et al.

Antioxidants, Journal Year: 2020, Volume and Issue: 9(8), P. 706 - 706

Published: Aug. 4, 2020

Lycopene, belonging to the carotenoids, is a tetraterpene compound abundantly found in tomato and tomato-based products. It fundamentally recognized as potent antioxidant non-pro-vitamin A carotenoid. Lycopene has been be efficient ameliorating cancer insurgences, diabetes mellitus, cardiac complications, oxidative stress-mediated malfunctions, inflammatory events, skin bone diseases, hepatic, neural reproductive disorders. This review summarizes information regarding its sources uses amongst different societies, biochemistry aspects, potential utilization of lycopene possible mechanisms involved alleviating abovementioned Furthermore, future directions with use this nutraceutical against lifestyle-related disorders are emphasized. Its protective effects recommended doses toxic agents toxicity safety also discussed.

Language: Английский

Citations

293

Carotenoids: Dietary Sources, Extraction, Encapsulation, Bioavailability, and Health Benefits—A Review of Recent Advancements DOI Creative Commons
Ramesh Kumar Saini,

Prasad Parchuri,

Veeresh Lokesh

et al.

Antioxidants, Journal Year: 2022, Volume and Issue: 11(4), P. 795 - 795

Published: April 18, 2022

Natural carotenoids (CARs), viz. β-carotene, lutein, astaxanthin, bixin, norbixin, capsanthin, lycopene, canthaxanthin, β-Apo-8-carotenal, zeaxanthin, and β-apo-8-carotenal-ester, are being studied as potential candidates in fields such food, feed, nutraceuticals, cosmeceuticals. CAR research is advancing the following three major fields: (1) production from natural sources optimization of its downstream processing; (2) encapsulation for enhanced physical chemical properties; (3) preclinical, clinical, epidemiological studies CARs’ health benefits. This review critically discusses recent developments chemistry antioxidant activity, marketing trends, dietary sources, extraction, bioaccessibility bioavailability, methods, intake, benefits CARs. Preclinical, on cancer, obesity, type 2 diabetes (T2D), cardiovascular diseases (CVD), osteoporosis, neurodegenerative disease, mental health, eye, skin also discussed.

Language: Английский

Citations

175

Tomatoes: An Extensive Review of the Associated Health Impacts of Tomatoes and Factors That Can Affect Their Cultivation DOI Creative Commons
Edward Collins, Cressida Bowyer,

Audrey Tsouza

et al.

Biology, Journal Year: 2022, Volume and Issue: 11(2), P. 239 - 239

Published: Feb. 4, 2022

This review outlines the health benefits associated with regular consumption of tomatoes and tomato products. The first section provides a detailed account horticultural techniques that can impact quality fruit its nutritional properties, including water availability, light intensity, temperature, growing media. next information on components are likely to contribute effects. then details some consumption, anticancer cardiovascular neurodegenerative diseases skin health. also discusses have gut microbiome benefits, reducing risk inflammatory bowel diseases. Other eating discussed in relation effects diabetes, immune response, exercise recovery, fertility. Finally, this addresses negative occur as result overconsumption products lycopene supplements.

Language: Английский

Citations

158

Overview of the Potential Beneficial Effects of Carotenoids on Consumer Health and Well-Being DOI Creative Commons
Pasquale Crupi, Maria Felicia Faienza,

Muhammad Yasir Naeem

et al.

Antioxidants, Journal Year: 2023, Volume and Issue: 12(5), P. 1069 - 1069

Published: May 10, 2023

Well-known experimental research demonstrates that oxidative stress is the leading cause of onset and progression major human health disorders such as cardiovascular, neurological, metabolic, cancer diseases. A high concentration reactive oxygen species (ROS) nitrogen leads to damage proteins, lipids, DNA associated with susceptibility chronic degenerative disorders. Biological pharmaceutical investigations have recently focused on exploring both its defense mechanisms manage Therefore, in recent years there has been considerable interest bioactive food plant compounds naturally occurring antioxidant sources able prevent, reverse, and/or reduce disease. To contribute this aim, herein, we reviewed beneficial effects carotenoids health. Carotenoids are widely existing natural fruits vegetables. Increasing confirmed various biological activities, antioxidant, anti-tumor, anti-diabetic, anti-aging, anti-inflammatory activities. This paper presents an overview latest progress biochemistry preventative therapeutic benefits carotenoids, particularly lycopene, promoting review could be a starting point for improving investigation possible ingredients functional foods nutraceuticals fields healthy products, cosmetics, medicine, chemical industry.

Language: Английский

Citations

105

Tomato pomace as a source of valuable functional ingredients for improving physicochemical and sensory properties and extending the shelf life of foods: A review DOI Creative Commons
Ifagbémi Bienvenue Chabı, Oscar Zannou,

Emmanuelle S.C.A. Dedehou

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(3), P. e25261 - e25261

Published: Jan. 29, 2024

Due to its nutritional and bioactive content, tomato pomace (TP) remains among the world's richest fruits vegetables. Tomatoes TP (generated coproduct) are a very rich source of lycopene other carotenoid compounds contain an essential amount polyphenols, policosanol, phytosterols, organic acids, dietary fibers, minerals, vitamins. is promising significant with antioxidant antimicrobial potential. Therefore, their consumption known be effective in preventing certain chronic diseases. For example, prevents prostate cancer acts as hepatoprotector genoprotector against mycotoxins, pesticide residues, heavy metals. Thus, valorization food ingredient can great health, economic environmental interest contribute improving nutrition security. During last decades, considerable efforts have been made valorize crucial functional improving: (i) properties, (ii) sensory characteristics (iii) shelf life many foods. The current review aims update summarize knowledge on recent applications TP, particularly use improve properties

Language: Английский

Citations

18

Preparation of sodium alginate/konjac glucomannan active films containing lycopene microcapsules and the effects of these films on sweet cherry preservation DOI

Yuanbo Zeng,

Yue Wang, Jinhui Tang

et al.

International Journal of Biological Macromolecules, Journal Year: 2022, Volume and Issue: 215, P. 67 - 78

Published: June 16, 2022

Language: Английский

Citations

55

Clinical Evidence of the Benefits of Phytonutrients in Human Healthcare DOI Open Access
Nicolas Monjotin, Marie Josèphe Amiot,

Jacques Fleurentin

et al.

Nutrients, Journal Year: 2022, Volume and Issue: 14(9), P. 1712 - 1712

Published: April 20, 2022

Phytonutrients comprise many different chemicals, including carotenoids, indoles, glucosinolates, organosulfur compounds, phytosterols, polyphenols, and saponins. This review focuses on the human healthcare benefits of seven phytochemical families highlights significant potential contribution phytonutrients in prevention management pathologies symptoms field family health. The structure function these their dietary sources are presented, along with an overview activities across health therapeutic targets. evaluation has enabled complementary effects same area to be recognized.

Language: Английский

Citations

53

The Importance of Antioxidant Activity for the Health-Promoting Effect of Lycopene DOI Open Access
Anna Kulawik, Judyta Cielecka‐Piontek, Przemysław Zalewski

et al.

Nutrients, Journal Year: 2023, Volume and Issue: 15(17), P. 3821 - 3821

Published: Aug. 31, 2023

Lycopene is a compound of colored origin that shows strong antioxidant activity. The positive effect lycopene the result its pleiotropic effect. ability to neutralize free radicals via one foundations pro-health effect, including inhibit development many civilization diseases. Therefore, this study focuses on importance in inhibiting diseases such as cardiovascular diseases, within nervous system, diabetes, liver and ulcerative colitis. According research mentioned, supplementation has significant promise for treatment illnesses marked by chronic inflammation oxidative stress. However, majority supporting data lycopene′s health benefits comes from experimental research, whereas evidence clinical studies both scarcer less certain any benefits. Research humans still required establish effectiveness.

Language: Английский

Citations

29

Underutilized plants increase biodiversity, improve food and nutrition security, reduce malnutrition, and enhance human health and well-being. Let’s put them back on the plate! DOI Creative Commons
Marija Knez, Marija Ranić, Mirjana Gurinović

et al.

Nutrition Reviews, Journal Year: 2023, Volume and Issue: 82(8), P. 1111 - 1124

Published: Aug. 29, 2023

Abstract The global food system depends on a limited number of plant species. Plants with unsatisfactory nutritional value are overproduced, whereas the wide variety nutrient-rich species used in earlier times remains neglected. Basing our diet few crops has wide-ranging negative consequences nutrition and security. Although still under-researched, underutilized plants slowly starting to receive increased recognition. These have superior content immense potential contribute security sustainability. This narrative review provides evidence encourage promotion, domestication, commercialization plants. anti-inflammatory, antidiabetic, anticancer effects some presented this review. outstanding ability forgotten increase security, boost dietary diversity, reduce malnutrition, enhance human health well-being is demonstrated. main barriers obstacles reintroducing foods reviewed recommendations for overcoming dietary-related challenges re-establishing into presented. expansion use paramount importance. exceptional properties, bioactive potential, proven benefits indicate that these should be strongly supported. Besides benefits, marginalized improve people’s lives many ways, retain biodiversity, develop local economies. Therefore, broader context well-balanced healthy diets.

Language: Английский

Citations

28