Nutrients,
Journal Year:
2024,
Volume and Issue:
16(21), P. 3709 - 3709
Published: Oct. 30, 2024
Diabetes
mellitus
(DM)
is
currently
regarded
as
a
global
public
health
crisis
for
which
lifelong
treatment
with
conventional
drugs
presents
limitations
in
terms
of
side
effects,
accessibility,
and
cost.
Type
2
diabetes
(T2DM),
usually
associated
obesity,
characterized
by
elevated
blood
glucose
levels,
hyperlipidemia,
chronic
inflammation,
impaired
β-cell
function,
insulin
resistance.
If
left
untreated
or
when
poorly
controlled,
DM
increases
the
risk
vascular
complications
such
hypertension,
nephropathy,
neuropathy,
retinopathy,
can
be
severely
debilitating
life-threatening.
Plant-based
foods
represent
promising
natural
approach
management
T2DM
due
to
vast
array
phytochemicals
they
contain.
Numerous
epidemiological
studies
have
highlighted
importance
diet
rich
plant-based
(vegetables,
fruits,
spices,
condiments)
prevention
DM.
Unlike
medications,
products
are
widely
accessible,
affordable,
generally
free
from
adverse
effects.
Integrating
plant-derived
into
daily
not
only
helps
control
hyperglycemia
observed
but
also
supports
weight
obese
individuals
has
broad
benefits.
In
this
review,
we
provide
an
overview
pathogenesis
current
therapeutic
DM,
particular
focus
on
potential
foods.
Foods,
Journal Year:
2020,
Volume and Issue:
10(1), P. 45 - 45
Published: Dec. 26, 2020
Tomatoes
are
consumed
worldwide
as
fresh
vegetables
because
of
their
high
contents
essential
nutrients
and
antioxidant-rich
phytochemicals.
contain
minerals,
vitamins,
proteins,
amino
acids
(leucine,
threonine,
valine,
histidine,
lysine,
arginine),
monounsaturated
fatty
(linoleic
linolenic
acids),
carotenoids
(lycopene
β-carotenoids)
phytosterols
(β-sitosterol,
campesterol
stigmasterol).
Lycopene
is
the
main
dietary
carotenoid
in
tomato
tomato-based
food
products
lycopene
consumption
by
humans
has
been
reported
to
protect
against
cancer,
cardiovascular
diseases,
cognitive
function
osteoporosis.
Among
phenolic
compounds
present
tomato,
quercetin,
kaempferol,
naringenin,
caffeic
acid
lutein
most
common.
Many
these
have
antioxidant
activities
effective
protecting
human
body
various
oxidative
stress-related
diseases.
Dietary
tomatoes
increase
body's
level
antioxidants,
trapping
reactive
oxygen
species
reducing
damage
important
biomolecules
such
membrane
lipids,
enzymatic
proteins
DNA,
thereby
ameliorating
stress.
We
reviewed
nutritional
phytochemical
compositions
tomatoes.
In
addition,
impacts
constituents
on
health,
particularly
some
degenerative
also
discussed.
Antioxidants,
Journal Year:
2020,
Volume and Issue:
9(8), P. 706 - 706
Published: Aug. 4, 2020
Lycopene,
belonging
to
the
carotenoids,
is
a
tetraterpene
compound
abundantly
found
in
tomato
and
tomato-based
products.
It
fundamentally
recognized
as
potent
antioxidant
non-pro-vitamin
A
carotenoid.
Lycopene
has
been
be
efficient
ameliorating
cancer
insurgences,
diabetes
mellitus,
cardiac
complications,
oxidative
stress-mediated
malfunctions,
inflammatory
events,
skin
bone
diseases,
hepatic,
neural
reproductive
disorders.
This
review
summarizes
information
regarding
its
sources
uses
amongst
different
societies,
biochemistry
aspects,
potential
utilization
of
lycopene
possible
mechanisms
involved
alleviating
abovementioned
Furthermore,
future
directions
with
use
this
nutraceutical
against
lifestyle-related
disorders
are
emphasized.
Its
protective
effects
recommended
doses
toxic
agents
toxicity
safety
also
discussed.
Antioxidants,
Journal Year:
2022,
Volume and Issue:
11(4), P. 795 - 795
Published: April 18, 2022
Natural
carotenoids
(CARs),
viz.
β-carotene,
lutein,
astaxanthin,
bixin,
norbixin,
capsanthin,
lycopene,
canthaxanthin,
β-Apo-8-carotenal,
zeaxanthin,
and
β-apo-8-carotenal-ester,
are
being
studied
as
potential
candidates
in
fields
such
food,
feed,
nutraceuticals,
cosmeceuticals.
CAR
research
is
advancing
the
following
three
major
fields:
(1)
production
from
natural
sources
optimization
of
its
downstream
processing;
(2)
encapsulation
for
enhanced
physical
chemical
properties;
(3)
preclinical,
clinical,
epidemiological
studies
CARs’
health
benefits.
This
review
critically
discusses
recent
developments
chemistry
antioxidant
activity,
marketing
trends,
dietary
sources,
extraction,
bioaccessibility
bioavailability,
methods,
intake,
benefits
CARs.
Preclinical,
on
cancer,
obesity,
type
2
diabetes
(T2D),
cardiovascular
diseases
(CVD),
osteoporosis,
neurodegenerative
disease,
mental
health,
eye,
skin
also
discussed.
Biology,
Journal Year:
2022,
Volume and Issue:
11(2), P. 239 - 239
Published: Feb. 4, 2022
This
review
outlines
the
health
benefits
associated
with
regular
consumption
of
tomatoes
and
tomato
products.
The
first
section
provides
a
detailed
account
horticultural
techniques
that
can
impact
quality
fruit
its
nutritional
properties,
including
water
availability,
light
intensity,
temperature,
growing
media.
next
information
on
components
are
likely
to
contribute
effects.
then
details
some
consumption,
anticancer
cardiovascular
neurodegenerative
diseases
skin
health.
also
discusses
have
gut
microbiome
benefits,
reducing
risk
inflammatory
bowel
diseases.
Other
eating
discussed
in
relation
effects
diabetes,
immune
response,
exercise
recovery,
fertility.
Finally,
this
addresses
negative
occur
as
result
overconsumption
products
lycopene
supplements.
Antioxidants,
Journal Year:
2023,
Volume and Issue:
12(5), P. 1069 - 1069
Published: May 10, 2023
Well-known
experimental
research
demonstrates
that
oxidative
stress
is
the
leading
cause
of
onset
and
progression
major
human
health
disorders
such
as
cardiovascular,
neurological,
metabolic,
cancer
diseases.
A
high
concentration
reactive
oxygen
species
(ROS)
nitrogen
leads
to
damage
proteins,
lipids,
DNA
associated
with
susceptibility
chronic
degenerative
disorders.
Biological
pharmaceutical
investigations
have
recently
focused
on
exploring
both
its
defense
mechanisms
manage
Therefore,
in
recent
years
there
has
been
considerable
interest
bioactive
food
plant
compounds
naturally
occurring
antioxidant
sources
able
prevent,
reverse,
and/or
reduce
disease.
To
contribute
this
aim,
herein,
we
reviewed
beneficial
effects
carotenoids
health.
Carotenoids
are
widely
existing
natural
fruits
vegetables.
Increasing
confirmed
various
biological
activities,
antioxidant,
anti-tumor,
anti-diabetic,
anti-aging,
anti-inflammatory
activities.
This
paper
presents
an
overview
latest
progress
biochemistry
preventative
therapeutic
benefits
carotenoids,
particularly
lycopene,
promoting
review
could
be
a
starting
point
for
improving
investigation
possible
ingredients
functional
foods
nutraceuticals
fields
healthy
products,
cosmetics,
medicine,
chemical
industry.
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(3), P. e25261 - e25261
Published: Jan. 29, 2024
Due
to
its
nutritional
and
bioactive
content,
tomato
pomace
(TP)
remains
among
the
world's
richest
fruits
vegetables.
Tomatoes
TP
(generated
coproduct)
are
a
very
rich
source
of
lycopene
other
carotenoid
compounds
contain
an
essential
amount
polyphenols,
policosanol,
phytosterols,
organic
acids,
dietary
fibers,
minerals,
vitamins.
is
promising
significant
with
antioxidant
antimicrobial
potential.
Therefore,
their
consumption
known
be
effective
in
preventing
certain
chronic
diseases.
For
example,
prevents
prostate
cancer
acts
as
hepatoprotector
genoprotector
against
mycotoxins,
pesticide
residues,
heavy
metals.
Thus,
valorization
food
ingredient
can
great
health,
economic
environmental
interest
contribute
improving
nutrition
security.
During
last
decades,
considerable
efforts
have
been
made
valorize
crucial
functional
improving:
(i)
properties,
(ii)
sensory
characteristics
(iii)
shelf
life
many
foods.
The
current
review
aims
update
summarize
knowledge
on
recent
applications
TP,
particularly
use
improve
properties
Nutrients,
Journal Year:
2022,
Volume and Issue:
14(9), P. 1712 - 1712
Published: April 20, 2022
Phytonutrients
comprise
many
different
chemicals,
including
carotenoids,
indoles,
glucosinolates,
organosulfur
compounds,
phytosterols,
polyphenols,
and
saponins.
This
review
focuses
on
the
human
healthcare
benefits
of
seven
phytochemical
families
highlights
significant
potential
contribution
phytonutrients
in
prevention
management
pathologies
symptoms
field
family
health.
The
structure
function
these
their
dietary
sources
are
presented,
along
with
an
overview
activities
across
health
therapeutic
targets.
evaluation
has
enabled
complementary
effects
same
area
to
be
recognized.
Nutrients,
Journal Year:
2023,
Volume and Issue:
15(17), P. 3821 - 3821
Published: Aug. 31, 2023
Lycopene
is
a
compound
of
colored
origin
that
shows
strong
antioxidant
activity.
The
positive
effect
lycopene
the
result
its
pleiotropic
effect.
ability
to
neutralize
free
radicals
via
one
foundations
pro-health
effect,
including
inhibit
development
many
civilization
diseases.
Therefore,
this
study
focuses
on
importance
in
inhibiting
diseases
such
as
cardiovascular
diseases,
within
nervous
system,
diabetes,
liver
and
ulcerative
colitis.
According
research
mentioned,
supplementation
has
significant
promise
for
treatment
illnesses
marked
by
chronic
inflammation
oxidative
stress.
However,
majority
supporting
data
lycopene′s
health
benefits
comes
from
experimental
research,
whereas
evidence
clinical
studies
both
scarcer
less
certain
any
benefits.
Research
humans
still
required
establish
effectiveness.
Nutrition Reviews,
Journal Year:
2023,
Volume and Issue:
82(8), P. 1111 - 1124
Published: Aug. 29, 2023
Abstract
The
global
food
system
depends
on
a
limited
number
of
plant
species.
Plants
with
unsatisfactory
nutritional
value
are
overproduced,
whereas
the
wide
variety
nutrient-rich
species
used
in
earlier
times
remains
neglected.
Basing
our
diet
few
crops
has
wide-ranging
negative
consequences
nutrition
and
security.
Although
still
under-researched,
underutilized
plants
slowly
starting
to
receive
increased
recognition.
These
have
superior
content
immense
potential
contribute
security
sustainability.
This
narrative
review
provides
evidence
encourage
promotion,
domestication,
commercialization
plants.
anti-inflammatory,
antidiabetic,
anticancer
effects
some
presented
this
review.
outstanding
ability
forgotten
increase
security,
boost
dietary
diversity,
reduce
malnutrition,
enhance
human
health
well-being
is
demonstrated.
main
barriers
obstacles
reintroducing
foods
reviewed
recommendations
for
overcoming
dietary-related
challenges
re-establishing
into
presented.
expansion
use
paramount
importance.
exceptional
properties,
bioactive
potential,
proven
benefits
indicate
that
these
should
be
strongly
supported.
Besides
benefits,
marginalized
improve
people’s
lives
many
ways,
retain
biodiversity,
develop
local
economies.
Therefore,
broader
context
well-balanced
healthy
diets.