The Lancet Countdown on health and climate change: from 25 years of inaction to a global transformation for public health

The Lancet, Journal Year: 2017, Volume and Issue: 391(10120), P. 581 - 630

Published: Oct. 30, 2017

Language: Английский

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Aerosol Health Effects from Molecular to Global Scales

Environmental Science & Technology, Journal Year: 2017, Volume and Issue: 51(23), P. 13545 - 13567

Published: Nov. 7, 2017

Poor air quality is globally the largest environmental health risk. Epidemiological studies have uncovered clear relationships of gaseous pollutants and particulate matter (PM) with adverse outcomes, including mortality by cardiovascular respiratory diseases. Studies impacts aerosols are highly multidisciplinary a broad range scales in space time. We assess recent advances future challenges regarding aerosol effects on from molecular to global through epidemiological studies, field measurements, health-related properties PM, multiphase interactions oxidants PM upon deposition. Global modeling combined exposure-response functions indicates that ambient pollution causes more than four million premature deaths per year. usually refer mass concentrations, but some may relate specific constituents such as bioaerosols, polycyclic aromatic compounds, transition metals. Various analytical techniques cellular assays applied redox activity formation reactive oxygen species. Multiphase chemical lung antioxidants atmospheric crucial mechanistic understanding oxidative stress The role distinct components needs be clarified integrated research various spatiotemporal for better evaluation mitigation public Anthropocene.

Language: Английский

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The need for clean air: The way air pollution and climate change affect allergic rhinitis and asthma

Allergy, Journal Year: 2020, Volume and Issue: 75(9), P. 2170 - 2184

Published: Jan. 9, 2020

Abstract Air pollution and climate change have a significant impact on human health well‐being contribute to the onset aggravation of allergic rhinitis asthma among other chronic respiratory diseases. In Westernized countries, households experienced process increasing insulation individuals tend spend most their time indoors. These sequelae implicate high exposure indoor allergens (house dust mites, pets, molds, etc), tobacco smoke, pollutants, which an health. Outdoor air derived from traffic activities not only has direct negative effect but also enhances allergenicity some plants contributes global warming. Climate modifies availability distribution plant‐ fungal‐derived increases frequency extreme events. This review summarizes effects pollution, outdoor subsequent in children adults addresses policy adjustments lifestyle changes required mitigate deleterious effects.

Language: Английский

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Climate Change, Fossil-Fuel Pollution, and Children’s Health

New England Journal of Medicine, Journal Year: 2022, Volume and Issue: 386(24), P. 2303 - 2314

Published: June 15, 2022

Language: Английский

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Air pollution: a global problem needs local fixes

Nature, Journal Year: 2019, Volume and Issue: 570(7762), P. 437 - 439

Published: June 1, 2019

Language: Английский

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Designing vegetation barriers for urban air pollution abatement: a practical review for appropriate plant species selection

npj Climate and Atmospheric Science, Journal Year: 2020, Volume and Issue: 3(1)

Published: March 26, 2020

Vegetation can form a barrier between traffic emissions and adjacent areas, but the optimal configuration plant composition of such green infrastructure (GI) are currently unclear. We examined literature on aspects GI that influence ambient air quality, with particular focus vegetation barriers in open-road environments. Findings were critically evaluated order to identify principles for effective design, recommendations regarding selection established reference relevant spatial scales. As an initial investigation into viable species UK urban GI, we compiled data 12 influential traits 61 tree species, created supplementary framework. found if scale intervention, context conditions site target pollutant type appreciated, plants exhibit certain biophysical enhance pollution mitigation. For super-micrometre particles, advantageous leaf micromorphological include presence trichomes ridges or grooves. Stomatal characteristics more significant sub-micrometre particle gaseous uptake, although comparative dearth studies pollutants. Generally macromorphological small size high complexity, height, density depend planting respect immediate physical environment. Biogenic volatile organic compound pollen be minimised by appropriate selection, their significance varies context. While this review assembled evidence-based practitioners, several important areas future research identified.

Language: Английский

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External exposome and allergic respiratory and skin diseases

Journal of Allergy and Clinical Immunology, Journal Year: 2018, Volume and Issue: 141(3), P. 846 - 857

Published: March 1, 2018

Language: Английский

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Contributions of City-Specific Fine Particulate Matter (PM_2.5) to Differential In Vitro Oxidative Stress and Toxicity Implications between Beijing and Guangzhou of China

Environmental Science & Technology, Journal Year: 2019, Volume and Issue: 53(5), P. 2881 - 2891

Published: Feb. 7, 2019

Growing literature has documented varying toxic potencies of source- or site-specific fine particulate matter (PM2.5), as opposed to the practice that treats particle toxicities independent composition given incomplete understanding toxicity constituents. Quantifying component-specific contribution is key unlocking geographical disparities from a mixture perspective. In this study, we performed integrated mixture–toxicity experiments and modeling quantify metals polycyclic aromatic hydrocarbons (PAHs), two default culprit component groups PM2.5 toxicity, in vitro oxidative stress caused by wintertime Beijing Guangzhou, megacities China. exhibited greater at equal mass concentrations. The targeted chemical analysis revealed higher burden PAHs per unit Beijing. These chemicals together explained 38 24% on average PM2.5-induced reactive oxygen species respectively, while >60% effects remained be resolved terms contributing chemicals. contributed approximately twice share metals. Fe, Cu, Mn were dominant metals, constituting >80% metal-shared proportion effects. Dibenzo[a,l]pyrene alone >65% PAH-shared significant coal combustion vehicular emissions suggested major source toxicologically active between cities. Our study provided novel quantitative insights into role profiles shaping differential city-specific pollution.

Language: Английский

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Bibliometric analysis of peer-reviewed literature on climate change and human health with an emphasis on infectious diseases

Globalization and Health, Journal Year: 2020, Volume and Issue: 16(1)

Published: May 8, 2020

Abstract Background Assessing research activity is important for planning future protective and adaptive policies. The objective of the current study was to assess on climate change health with an emphasis infectious diseases. Method A bibliometric method applied using SciVerse Scopus. Documents human were called “health-related literature” while documents diseases “infection-related literature”. period from 1980 2019. Results search query found 4247 in health-related literature 1207 infection-related literature. growth publications showed a steep increase after 2007. There four themes literature: (1) diseases; (2) change, public food security; (3) heat waves, mortality, non-communicable (4) air pollution, allergy, respiratory health. most frequently encountered pathogens/infectious malaria dengue. had higher h -index than top-cited focused security, health, those water-, vector-, mosquito-borne European region highest contribution ( n = 1626; 38.3%) 497; 41.2%). USA led 1235 (29.1%) 365 (30.2%) Australian National University ranked first London School Hygiene & Tropical Medicine International collaboration inadequate. published Environmental Health Perspectives journal received citations per document. total 1416 (33.3%) funded 419 (34.7%) funded. Conclusion Research rise issues making good share. should be supported. Future needs focus impact psychosocial, mental, innovations, policies, preparedness systems.

Language: Английский

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Defining the Scope of Exposome Studies and Research Needs from a Multidisciplinary Perspective

Environmental Science & Technology Letters, Journal Year: 2021, Volume and Issue: 8(10), P. 839 - 852

Published: Sept. 7, 2021

The concept of the exposome was introduced over 15 years ago to reflect important role that environment exerts on health and disease. While originally viewed as a call-to-arms develop more comprehensive exposure assessment methods applicable at individual level throughout life course, scope has now expanded include associated biological response. In order explore these concepts, workshop hosted by Gunma University Initiative for Advanced Research (GIAR, Japan) discuss exposomics from an international multidisciplinary perspective. This Global Perspective is summary discussions with emphasis (1) top-down, bottom-up, functional approaches exposomics, (2) need integration standardization LC- GC-based high-resolution mass spectrometry untargeted analyses, (3) design study, (4) requirement open science workflows including spectral libraries public databases, (5) necessity large investments in infrastructure sequence exposome, (6) precision medicine nutrition create personalized environmental profiles. Recommendations are made key issues encourage continued advancement cooperation exposomics.

Language: Английский

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